Lintlha-khōlō Tsa
Phuputso e entsoeng ke bafuputsi ba Japane e entsoeng ke bafuputsi ba Japane, e bulehileng, e entsoeng ke setsi se le seng, e khothalelitse hore tekanyo ea letsatsi le letsatsi ea 12 g ea GBS-01, e nang le hoo e ka bang 4g ea litholoana tsa burdock e nang le arctigenin e ngata, e ka ba e sireletsehileng ea bongaka 'me e ka ba le melemo e ka bang teng. bakuli ba nang le pancreatic e tsoetseng pele tsoaroa ke kankere refractory ho kalafo ea Gemcitabine. Leha ho le joalo, liteko tse hlalositsoeng hantle li hlokahala ho fumana liphetho tsena.
Burdock le metsoako ea eona e sebetsang
Arctium lappa, eo ka tloaelo e tsejoang e le burdock, ke semela se sa feleng se tsoang Asia le Europe. Burdock e se e tsebahala lefatšeng ka bophara 'me ea lengoa le ho sebelisoa e le meroho libakeng tse ngata tsa lefats'e. Metso, makhasi le lipeo tsa semela sena li sebelisoa meriana ea setso ea China e le pheko ea maloetse a fapaneng. Metso ea Burdock e tletse li-antioxidants hape e nkuoa e na le litlamorao tse khahlanong le mofets'e.
Liphuputso tse fapaneng tse entsoeng pele ho nako li bontšitse hore burdock e ka ba le li-anti-inflammatory, antibacterial, antidiabetic, antiulcerogenic, hepatoprotective le anticancer. Metsoako ea bohlokoa ea lihlahisoa tsa burdock e kenyelletsa lihlahisoa tsa caffeoylquinic acid, lignans le li-flavonoids tse fapaneng.
Makhasi a burdock haholo-holo a na le mefuta e 'meli ea lignans:
- Arctiin
- Arctigenin
Ntle le tsena, phenolic acid, quercetin, quercitrin le luteolin le tsona li ka fumanoa makhasi a burdock.
Peo ea Burdock e na le li-phenolic acid tse kang Caffeic acid, Chlorogenic acid le Cynarin.
Metsoako ea mantlha e sebetsang metsong ea Burdock ke Arctiin, Luteolin le Quercetin rhamnoside e ka bang le lebaka la litlamorao tsa tsona tse ka bang khahlanong le mofets'e.
Ts'ebeliso ea lihlahisoa tsa Burdock
Burdock e sebelisitsoe haholo ho Meriana ea Setso ea China ka sepheo se latelang, leha ho se na bopaki ba bongaka bo tšehetsang ts'ebeliso ea eona maemong a mangata:
- Ho hloekisa mali
- Ho fokotsa khatello ea kelello
- Ho fokotsa gout
- Fokotsa lefu la sebete
- Ho fokotsa tšoaetso ea likokoana-hloko
- Ho fokotsa tsoekere ea mali ho bakuli ba nang le lefu la tsoekere
- Ho phekola mathata a letlalo a kang eczema le psoriasis
- Ho fokotsa wrinkles
- Ho phekola mathata a ho ruruha
- Ho phekola AIDS
- Ho Phekola Kankere
- Joaloka diuretic
- Joaloka tee ea antipyretic ea ho phekola feberu
Lijo Tseo U ka li Jang Kamora Ho Khetholla Kankere!
Ha ho kankere tse peli tse tšoanang. Fetela ka n the'ane ho tataiso e tloaelehileng ea phepo bakeng sa motho e mong le e mong 'me u etse liqeto tse ikhethileng mabapi le lijo le li-supplement ka kholiseho.
Na Burdock Extracts E Tla Thusa bakuli ba Kankere ea Pancreatic ba hanyetsang Gemcitabine?
Ho ea ka American Cancer Society, kankere ea pancreatic ke ea borobong e atileng haholo tsoaroa ke kankere ho basali le mofetše oa leshome o atileng haholo ho banna mme o baka 7% ea mafu ohle a mofetše.
Hape ke sesosa sa bone se ka sehloohong sa lefu la mofets'e ho banna le basali.
Gemcitabine ke moemeli oa maemo a pele oa chemotherapeutic bakeng sa mofetše oa pancreatic. Leha ho le joalo, microenvelo ea mofetše oa pancreatic e tsebahala haholo ka ho ba le hypoxia e matla, boemo boo 'mele o amohuoang phepelo e lekaneng ea oksijene maemong a lisele, le khaello ea limatlafatsi, haholo-holo tsoekere. Hypoxia e ntlafatsa chemoresistance khahlanong le gemcitabine, ka hona e fokotsa melemo ea chemotherapy ena.
Kahoo, bafuputsi ba National Cancer Center Hospital East, Meiji Pharmaceutical University, National Cancer Center, Kracie Pharma, Ltd. e Toyama, le Tokyo University of Science, Japane ba hlahlobile metsoako e fapaneng e ka fokotsang mamello ea lisele tsa mofets'e ho tlala tlala ea tsoekere le hypoxia, le arctigenin e tsebahalang, e leng motsoako oa bohlokoa o fumanoang likhechong tsa Burdock, e le setsi se hloahloa sa likhetho bakeng sa teko ea bongaka, ka lebaka la ts'ebetso ea eona ea antitumor e bonoang mefuteng e mengata ea mofets'e ea xenograft le lifaele tse lekaneng tsa polokeho ha e fanoa ka tekanyetso ho fihlela makhetlo a 100 letsatsi ka leng lethal dose hlokahala bakeng sa antitumor mosebetsi ka litoeba. (Masafumi Ikeda et al, Cancer Sci., 2016)
Bafuputsi ba sebelisitse sethethefatsi sa molomo GBS-01, e nkiloeng tholoaneng ea Burdock, e ruileng ka arctigenin, ho bakuli ba 15 ba nang le pancreatic e tsoetseng pele. tsoaroa ke kankere refractory to gemcitabine. Nyeoeng, ba ile ba batlisisa tekanyo e phahameng e mamelloang ea GBS-01 mme ba sheba chefo e fokotsang Tekanyetso. Dose-limiting toxicity (DLTs) e bolela ponahalo ea grade 4 hematological/blood toxicity le grade 3 kapa 4 non-hematological/blood toxicity matsatsing a 28 a pele a phekolo.
Phuputsong, ba fumane hore ha ho na matšoao a chefo ea mali ea grade 4 le grade 3 kapa 4 tseo e seng chefo ho bakuli ba ngolisitsoeng, ho efe kapa efe ea litekanyetso tse tharo tse sebelisitsoeng (letsatsi le leng le le leng 3.0 g, 7.5 g kapa 12.0 g) . Leha ho le joalo, ho ile ha bonoa chefo e bobebe joalo ka ho eketseha ha serum γ ‐ glutamyl transpeptidase, ho eketsa tsoekere ea mali le ho eketsa palo ea bilirubin ea serum.
Phuputso e bonts'itse tekanyetso e khothalletsoang ea GBS-01, sehlahisoa se nang le arctigenin e ngata e tsoang Burdock, hore e be 12.0 g ka letsatsi, hobane ha ho li-DLT tse bonoang maemong afe kapa afe a litekanyetso tse tharo. Tekanyo ea letsatsi le letsatsi ea 12.0 g GBS-01 e ne e batla e lekana le 4.0 g ea litholoana tsa litholoana.
Ho tsoa ho bakuli ba jeleng karolo ea Burdock, bakuli ba 4 ba ne ba na le mafu a tsitsitseng mme 1 a bontša karabelo e sa reroang nakong ea tlhokomelo. Ho nepahala, sekhahla sa karabelo e ne e le 6.7% mme sekhahla sa taolo ea mafu e le 33.3%. Phuputso e boetse e fumane hore tsoelo-pele ea mahala le pholoho ea bakuli e ne e le likhoeli tsa 1.1 le likhoeli tsa 5.7, ka ho latellana.
fihlela qeto e
Li-extracts le metso ea Burdock li nkoa li na le li-anti-inflammatory, antibacterial, antidiabetic, antiulcerogenic, hepatoprotective, le anti-cancer properties. Phuputso ea kliniki ea mohato oa 2016 e entsoeng ke bafuputsi ba Japane e khothalelitse hore tekanyo ea letsatsi le letsatsi ea 12 g ea GBS-01 (e nang le hoo e ka bang 4.0 g ea litholoana tsa burdock e ruileng ka arctigenin) e ka ba e sireletsehileng ea bongaka 'me e ka ba le melemo e ka bang teng ho bakuli ba nang le pancreatic e tsoetseng pele. kankere refractory ho kalafo ea Gemcitabine. Leha ho le joalo, liteko tse kholo tse hlalositsoeng hantle lia hlokahala ho fumana liphuputso tsena, pele ho khothaletsa tšebeliso ea arctigenin ho bakuli ba mofetše oa pancreatic.
Lijo tseo u li jang le tse u tlatsetsang ke qeto eo u e etsang. Qeto ea hau e lokela ho kenyelletsa ho nahanisisa ka liphetoho tsa liphatsa tsa lefutso tsa mofetše, e leng mofetše, kalafo e tsoelang pele le litlatsetso, ho kula hohle, leseli la bophelo, boima, bolelele le litloaelo.
Morero oa phepo e nepahetseng bakeng sa mofets'e ho tsoa addon ha o ea ipapisa le lipatlisiso tsa inthanete. E iketsetsa liqeto bakeng sa hau e ipapisitse le mahlale a limolek'hule a kentsoeng tšebetsong ke bo-rasaense ba rona le lienjineri tsa software. Ho sa tsotelehe hore na o tsotella ho utloisisa metheo ea limolek'hule kapa che - bakeng sa moralo oa phepo ea mofets'e kutloisiso ea hlokahala.
Qala hona joale ka moralo oa hau oa phepo e nepahetseng ka ho araba lipotso lebitsong la mofetše, phetoho ea lefutso, kalafo e tsoelang pele le litlatsetso, ho kula hohle, litloaelo, mokhoa oa bophelo, sehlopha sa lilemo le bong.
Phepo e ikhethileng bakeng sa Kankere!
Kankere e fetoha ha nako e ntse e ea. Iketsetse 'me u fetole phepo ea hau ho latela sesupo sa mofets'e, kalafo, mokhoa oa bophelo, khetho ea lijo, lintho tse allergy le lintlha tse ling.
Bakuli ba mofets'e hangata ba tlameha ho sebetsana le tse fapaneng litla-morao tsa chemotherapy tse amang boleng ba bona ba bophelo le ho batla mekhoa e meng ea kalafo ea mofets'e. Ho nka phepo e nepahetseng le litlatsetso ho latela maikutlo a mahlale (ho qoba ho inahanela le ho khetha ka mokhoa o sa reroang) ke pheko ea tlholeho bakeng sa mofets'e le litla-morao tse amanang le kalafo