Lintlha-khōlō Tsa
Kalafo ea radiation e sebelisoa hangata ho phekola mofetše oa matsoele, empa hangata lisele tsa mofetše li ka hana kalafo ea radiation. Ho ja / ho sebelisoa ha Ellagic Acid ho tsoa lijong tse kang monokotsoai, kharenate le walnuts (tse ruileng ka motsoako ona oa phenolic) kapa li-supplement li na le melemo e mengata ea bophelo bo botle e kenyeletsang liphello tse khahlanong le kankere. Ellagic acid e boetse e ntlafatsa karabelo ea radiotherapy liseleng tsa mofetše oa matsoele ka nako e ts'oanang e le ts'ireletso ea radio ho lisele tse tloaelehileng: pheko ea tlhaho e ka bang teng bakeng sa sefuba. tsoaroa ke kankere.
Ellagic Acid ke eng?
Ellagic Acid ke ntho e hlahang ka tlhaho e bitsoang polyphenol e nang le thepa e matla ea antioxidant, e fumanoang litholoana le meroho e mengata. E boetse e fumaneha khoebong ka mokhoa oa li-supplement. Ellagic acid e na le litlamorao tse khahlano le ho ruruha ebile e na le litlamorao tse ngata bophelong bo botle.
Lijo tse ruileng ka Ellagic Acid: Ellagic acid e fumaneha hangata lijong tse fapaneng ho kenyeletsoa litholoana tse kang tse tala, fragole, monokotšoai o motšo, cranberries le likharenate. Lijo tse ling ho kenyelletsa linate tse ling tsa lifate tse kang walnuts le pecans le tsona li ruile ka Ellagic acid.
Melemo ea bophelo bo botle ba Ellagic Acid
Melemo e meng e ka bang teng ea bophelo bo botle ba litlatsetso tsa asiti ea Ellagic e kenyelletsa litlamorao tse khahlanong le mofets'e, ho fokotsa matšoao a mafu a sa foleng a ts'oaetso ho kenyelletsa le dyslipidemia, botenya (ka ts'ebeliso ea ellagic acid e tsoang ho kharenate) le mathata a amanang le botenya joalo ka insulin ho hanyetsa, mofuta oa 2 lefu la tsoekere, le lefu la sebete se mafura. (Inhae Kang et al, Adv Nutr., 2016Melemo e meng ea bophelo bo botle ea ho ja Ellagic Acid e boetse e kenyelletsa ho sitisa ho sosobana ha letlalo le ho ruruha ho amanang le ho pepeseha ha UV ho sa foleng. (Ji-Young Bae et al, Exp Dermatol., 2010)
Radiotherapy bakeng sa mofetše oa matsoele
Kankere ea matsoele ke mofuta o atileng haholo oa mofets'e ho basali lefats'eng ka bophara (https://www.wcrf.org). Ho tloha ka Pherekhong 2019, ho na le basali ba fetang limilione tse 3.1 ba nang le nalane ea mofets'e oa matsoele US feela, ho kenyeletsang basali ba ntseng ba tsoela pele kalafo kapa ba phethetsoe. (Lipalo-palo tsa Kankere ea Lebese ea Amerika; https://www.breastcancer.org). Kalafo ea mahlaseli kapa Radiotherapy ke o mong oa mekhoa ea tsoaroa ke kankere kalafo ntle le opereishene le chemotherapy mme e sebelisoa ka tloaelo ho alafa mekhahlelo ea pele ea mofetše oa matsoele joalo ka kalafo ea lehae kamora ho buuoa, ho thusa ho theola monyetla oa hore mofetše o khutle. Kalafo ea radiation e boetse e sebelisoa ha mofetše o khutletse hape ’me o nametse lithong tse ling tse kang boko le masapo, hammoho le liphekolo tse ling tse kang chemotherapy kapa immunotherapy.
Lijo Tseo U ka li Jang Kamora Ho Khetholla Kankere!
Ha ho kankere tse peli tse tšoanang. Fetela ka n the'ane ho tataiso e tloaelehileng ea phepo bakeng sa motho e mong le e mong 'me u etse liqeto tse ikhethileng mabapi le lijo le li-supplement ka kholiseho.
Ellagic Acid le Radiotherapy Kankere ea Lebele
Kalafo ea mahlaseli e sebetsa ka ho baka tšenyo ho DNA ea tsoaroa ke kankere lisele ka matla a phahameng a ionizing likaroloana. Leha ho le joalo, e boetse e baka tšenyo ea tebeletso ho lisele tse potolohileng tse tloaelehileng, tseo e seng tsa mofetše, tse bakang litla-morao tse sa batleheng le tse matla. Ho feta moo, ka tlhaho e ntseng e fetoha ka potlako ea lisele tsa mofetše, li lula li kopanya mochini oa tsona o kahare mme li khona ho phela ka radiotherapy le ho hanyetsa mahlaseli. Ho ntlafatsa menyetla ea katleho ea kalafo ea radiation ho bile le lipatlisiso tse ngata mabapi le metsoako ea radiosensitizer eo ha e kopantsoe le kalafo ea radiation e ka thusang ho fihlela tšenyo e kholo ea hlahala ha ka nako e ts'oanang e le radioprotective ea lisele tse se nang mofetše. Motsoako o mong o joalo oa tlhaho o bontšitseng ka liteko thepa ena e 'meli ea ho ba radiosensitizer ho lisele tsa mofetše oa matsoele le radioprotective ho lisele tse tloaelehileng ke motsoako oa phenolic o bitsoang Ellagic Acid.
Liphuputso tsa lisele tsa kankere ea matsoele MCF-7 li bontšitse hore Ellagic Acid hammoho le mahlaseli a kotsi a eketsa lefu la lisele tsa kankere ka 50-62% ha motsoako o tšoanang o ne o sireletsa liseleng tse tloaelehileng tsa NIH3T3. Mochine oo Ellagic Acid e ileng ea sebetsa ka oona ho matlafatsa matla a mahlaseli liseleng tsa mofetše oa matsoele e bile ka ho ama mitochondria hampe - lifeme tsa matla tsa lisele; ka ho eketsa pro cell-death; le ho fokotsa lintlha tsa pro-pholoha ho tsoaroa ke kankere sele. Liphuputso tse joalo li bontša hore metsoako ea tlhaho e kang Ellagic Acid e ka ’na ea sebelisoa ho “ntlafatsa radiotherapy ea mofetše ka ho eketsa chefo ea hlahala le ho fokotsa tšenyo e tloaelehileng ea lisele e bakoang ke mahlaseli.” (Ahire V. et al, Nutrition le Cancer, 2017)
fihlela qeto e
Ntle le tšusumetso ea radiosensitization liseleng tsa mofets'e, palo e kholo ea lithuto tsa mahlale e boetse e totobalitse likarolo tse ling tse ngata tsa anti-cancer tsa Ellagic Acid (eo hangata e fumanoang likharenate), ho tloha ho khona ho emisa ho ata ha lisele tsa mofetše, ho thusa ho hlohlelletsa lefu la lisele tsa mofetše le bitsoang apoptosis, thibelo ea ho ata ha mofets'e ka ho thibela kholo ea methapo e mecha ea mali le ho falla le tlhaselo ea lisele tsa mofetše likarolong tse ling tsa 'mele (Ceci C et al, Metsoako, 2018; Zhang H et al, Mofuta oa Kankere ea Kankere., 2014). Ho na le liteko tsa tleliniki tse ntseng li tsoela pele ka matšoao a fapaneng a mofets'e (monkere oa matsoele (NCT03482401), mofets'e oa colorectal (NCT01916239), mofets'e oa senya (NCT03535675) le tse ling) ho netefatsa melemo ea chemopreventive le kalafo ea Ellagic Acid ho bakuli ba mofets'e, joalo ka ha e bonoa mefuteng ea liteko ea tsoaroa ke kankere. Ho sa tsotellehe hore tlatsetso ena ea tlhaho ha e na chefo ebile e bolokehile, Ellagic acid e lokela ho sebelisoa feela ka ho buisana le litsebi tsa tlhokomelo ea bophelo, kaha e na le monyetla oa ho sebelisana le lithethefatsi tse ling ka lebaka la ho thibela li-enzyme tsa metabolizing sebeteng. Hape, ho khetha tekanyo e nepahetseng ea Ellagic acid e tlatselletsang le tlhahiso e nang le solubility e ntlafalitsoeng le bioavailability ea hlokahala ho fumana phello ea eona e felletseng ea kalafo.
Lijo tseo u li jang le tse u tlatsetsang ke qeto eo u e etsang. Qeto ea hau e lokela ho kenyelletsa ho nahanisisa ka liphetoho tsa liphatsa tsa lefutso tsa mofetše, e leng mofetše, kalafo e tsoelang pele le litlatsetso, ho kula hohle, leseli la bophelo, boima, bolelele le litloaelo.
Morero oa phepo e nepahetseng bakeng sa mofets'e ho tsoa addon ha o ea ipapisa le lipatlisiso tsa inthanete. E iketsetsa liqeto bakeng sa hau e ipapisitse le mahlale a limolek'hule a kentsoeng tšebetsong ke bo-rasaense ba rona le lienjineri tsa software. Ho sa tsotelehe hore na o tsotella ho utloisisa metheo ea limolek'hule kapa che - bakeng sa moralo oa phepo ea mofets'e kutloisiso ea hlokahala.
Qala hona joale ka moralo oa hau oa phepo e nepahetseng ka ho araba lipotso lebitsong la mofetše, phetoho ea lefutso, kalafo e tsoelang pele le litlatsetso, ho kula hohle, litloaelo, mokhoa oa bophelo, sehlopha sa lilemo le bong.
Phepo e ikhethileng bakeng sa Kankere!
Kankere e fetoha ha nako e ntse e ea. Iketsetse 'me u fetole phepo ea hau ho latela sesupo sa mofets'e, kalafo, mokhoa oa bophelo, khetho ea lijo, lintho tse allergy le lintlha tse ling.
Bakuli ba mofets'e hangata ba tlameha ho sebetsana le tse fapaneng litla-morao tsa chemotherapy tse amang boleng ba bona ba bophelo le ho batla mekhoa e meng ea kalafo ea mofets'e. Ho nka phepo e nepahetseng le litlatsetso ho latela maikutlo a mahlale (ho qoba ho inahanela le ho khetha ka mokhoa o sa reroang) ke pheko ea tlholeho bakeng sa mofets'e le litla-morao tse amanang le kalafo