Muchidimbu
Zvokudya zvesoya zvakakosha zvekudya zve isoflavones senge genistein, daidzein uye glycitein, iyo inoshanda se phytoestrogens (miti yakagadzirwa nemakemikari ane chimiro chakafanana neesrogen). Vazhinji Gomarara remuzamu ari estrogen receptor (hormone receptor) yakanaka uye nekudaro munhu anogona kutya kana kudya kwesoya kwakabatana nenjodzi yakawedzera yegomarara rezamu. Iyi blog inopfupikisa zvidzidzo zvakasiyana zvinoongorora kushamwaridzana pakati pekudya soy negomarara rezamu. Zvakawanikwa zveongororo idzi zvinoratidza kuti kudya chikafu chesoya zvine mwero hachiwedzere njodzi yegomarara rezamu, asi kutora soya yekuwedzera inogona kunge isiri sarudzo yakachengeteka.
Chikafu cheSoy chave chiri chikamu cheyakajairwa chikafu cheAsia kubvira makore mazhinji uye zvigadzirwa zvesoya zvichangobva kuwana mukurumbira pasirese. Nekuda kwehuwandu hwayo hwakawanda hweprotein, zvigadzirwa zve soya zvinoshandiswa zvakare seanalogy yakagwinya yenyama uye senzira dzakajairika dzekugadzirisa zvinovaka nyama. Mhando dzakasiyana dzezvikafu zve soy zvinosanganisira zvisina kuviriswa sosi zvekudya senge ma soya akazara, tofu, edamame uye mukaka we soya uye zvigadzirwa zvakaviriswa sosi sosi muto, yakaviriswa bhinzi, miso, nattō, uye tempeh.
Pamusoro pezvo, zvikafu zvesoya zvakare zvakakosha zvekudya masosi e-isoflavones senge genistein, daidzein uye glycitein. Isoflavones zvimiro zvezvirimwa zvinowira pasi pechikamu cheflavonoids chinoratidza antioxidant, anticancer, antimicrobial, uye anti-inflammatory properties. Isoflavones inoshanda se phytoestrogens, iyo isiri chinhu kunze kwemiti yakagadzirwa nemakemikari ane chimiro chakafanana neesrogen. Kubatanidzwa kwekudya kwesoya negomarara rezamu kwakadzidzwa zvakanyanyisa kwemakore mazhinji. Iyi blog inotarisana nezvidzidzo zvakasiyana izvo zvakaongorora kusangana kwechikafu chesoya nemazamu kenza.
Sangano pakati peSoy Foods neCancer Breast
Kansa yepabonde ndiyo yechipiri inotungamira kukonzera kufa kwekenza muvakadzi muna 2020. Zviitiko zvecancer yemazamu zvakawedzera zvishoma ne0.3% pagore mumakore achangopfuura (American Cancer Society). Inowanzoitika kune vakadzi vane makore ari pakati pe20-59 makore. Uye zvakare, kenza yemazamu inokwana makumi matatu kubva muzana evose vakadzi vegomarara (Kanzera Statistics, 2020). Makenza mazhinji emuzamu ane estrogen receptor (hormone receptor) yakanaka kenza yemazamu uye sezvakambotaurwa, zvekudya zve soy zvine maoflavones anoita se phytoestrogens. Nekudaro, mumwe anogona kutya kuti kudya kwesoy kunosanganisirwa nenjodzi yakawedzera yekenza yemazamu (inosanganisira estrogen receptor kenza yemazamu). Ngatitsvakei izvo zvinotaurwa nezvidzidzo!
Zviwanikwa kubva kuZvidzidzo zveSoy Chikafu uye Gomarara repazamu
1. Soy Intake uye Breast Cancer Risk muvakadzi vechiChinese
Imwe ongororo ichangoburwa yakaburitswa muEuropean Zvinyorwa zveEpidemiology yakaongorora hukama pakati pesoy kudya uye nengozi yekenza yemazamu. Vatsvagiridzi vakashandisa dhata kubva kuhukuru-hukuru hunotarisirwa hweboka rekudzidza hunodaidzwa kuti China Kadoorie Biobank (CKB) cohort chidzidzo chekuongorora. Chidzidzo ichi chaisanganisira vakadzi vanodarika mazana matatu ezviuru vane makore ari pakati pe300,000-30 kubva kumatunhu gumi nenzvimbo dzeupfumi muChina. Vakadzi ava vakanyoreswa pakati pa79 na10, uye vakateverwa-chiitiko checancer yemazamu kweanenge makore gumi. Pamusoro pezvo, vaongorori vakawana ruzivo rwekushandisa kwesoy kubva pamabvunzo emagetsi ezvekutanga, maviri akamutswa uye gumi nemaviri e2004-h yekudya inorangarira. (Wei Y et al, Eur J Epidemiol. 2019)
Zvinoenderana nedhata rakaunganidzwa, zvinoreva kuti soy kudya kwevakadzi ava yaive 9.4 mg / zuva. Vakadzi mazana maviri nemakumi masere nepfumbamwe vakagadzira kanzura yemazamu panguva yekutevera yemakore gumi. Yakadzama ongororo yedata haina kuwana chakakosha kusangana pakati pesoy kudya uye nekenza yemazamu zviitiko zvakazara.
Zvichakadaro, ivo vaongorori vakatsvaga uye vakawana zvisungo zvisere zvaitarisirwa zveboka kubva kuruzhinji rwevanhu uye vakaita mosi-yekuongorora mitezo. Iko kuongorora kwakaratidza kuti kune yega yega 8 mg / zuva rinowedzera mukudya kwe soy, pakanga paine 10% kudzikira mukenza yemazamu njodzi. (Wei Y et al, Eur J Epidemiol. 2019)
Makiyi Ekutora-aways:
Vatsvagiridzi vakagumisa kuti zvine mwero kudya sosi hakubatanidzwe kenza yemazamu panjodzi mune vakadzi veChinese. Ivo zvakare vakakurudzira kuti huwandu hwakawanda hwekudya kwesoy kudya hunogona kupa zvakaringana mabhenefiti ekuderedza kenza yemazamu njodzi.
2. Soy isoflavone Intake uye Menopausal Zviratidzo (MPS) pakati pevakadzi vechiChinese vane gomarara repazamu rekutanga
Mune ongororo ichangoburwa, vaongorori vakaferefeta kushamwaridzana kuri pakati soy isoflavone kunwa uye menopausal zviratidzo (MPS) pakati pevakadzi veChinese vanoonekwa kuti vane gomarara repazamu rekutanga. Chidzidzo ichi chakaburitswa muBreast Cancer Research and Treatment Journal muna Kubvumbi 2020. Yakashandisa remibvunzo yakavakirwa data kubva ku1462 veChinese varwere vekenza yemazamu. Paive nematatu ekutevera-nguva-nguva mukati memakore mashanu ekutanga mushure mekuongororwa. (Lei YY et al, Gomarara reMazamu Res Regedza. 2020)
Makiyi Ekutora-aways:
Zvakawanikwa zvakaratidza kusabatana pakati pesoy isoflavone kudya uye zviratidzo zvekumwedzi pakati pevarwere veChinese vekenza yemazamu.
3. Soy isoflavones uye Breast Cancer muPre- uye Post-Menopausal Vakadzi vanobva kuAsia nekuMadokero nyika
Meta-ongororo yakaburitswa muPLoS Imwe magazini muna 2014 yaisanganisira makumi matatu ezvidzidzo zvekutarisa zvinosanganisira premenopausal vakadzi uye makumi matatu neshanu anosanganisira postmenopausal vakadzi kuti vaongorore kusangana kwesoy isoflavone kudya nekenza yemazamu. Pakati pezvidzidzo zvinosanganisira vakadzi vasati vambomira kuenda kumwedzi, zvidzidzo gumi neshanu zvakaitwa munyika dzeAsia uye gumi nemana zvakaitwa munyika dzekuMadokero. Pakati pezvidzidzo zvinosanganisira vakadzi vanopera kuenda kumwedzi, zvidzidzo gumi nesere zvakaitwa munyika dzeAsia uye gumi nezvina zvakaitwa munyika dzekuMadokero. (Chen M et al, PLoS Mumwe. 2014)
Makiyi Ekutora-aways:
Vatsvakurudzi vakaona kuti soy isoflavone kudya kunogona kuderedza njodzi yekenza yemazamu kune vese premenopausal uye post-menopausal vakadzi munyika dzeAsia. Nekudaro, ivo havana kuwana humbowo hunoratidza kusangana pakati pesoy isoflavone kudya uye kenza yemazamu ye premenopausal kana post-menopausal vakadzi munyika dzekuMadokero.
4. Soy Kudya Kudya uye Chiitiko chekutyorwa kwepfupa muVanopona neCancer yeCancer
Muchidzidzo chikuru chinotarisirwa chinodaidzwa kuti "The Shanghai Breast Cancer Survival Study", vaongorori vakaongorora chiitiko chekutyoka kwemapfupa uye kushamwaridzana kwayo nekudya kwesoya mune vakapona kenza yemazamu. Chidzidzo ichi chaisanganisira data kubva ku4139 nhanho 0-III mazamu kenza varwere, 1987 pre-menopausal uye 2152 postmenopausal varwere. Soy chikafu chekudya chakaongororwa pa6 uye 18 mwedzi mushure mekuongororwa. Uyewo, kuputsika kwakaongororwa pamwedzi we18 uye pa3, 5, uye makore gumi mushure mekuongororwa.Zheng N et al, JNCI Kenza Spectr. 2019)
Kiyi kutora-aways:
Zviwanikwa kubva kuongororo zvinoratidza kuti kuwedzerwa kudyiwa kwesoy isoflavone kunogona kudzora njodzi yekutyoka kwemapfupa mune pre-menopausal varwere asi kwete mumashure-emamopaopausal varwere.
5. Soy isoflavones Kudya uye Kenza Yezamu Kudzokororazve
Muchidzidzo chakaitwa naKang X et al., vakaongorora hukama pakati pe soy isoflavones kutora uye kudzokorora kenza yemazamu uye kufa. Chidzidzo chakashandisa bvunzo-yakavakirwa data kubva ku524 mazamu kenza varwere kuti vaongororwe. Ongororo iyi yakaitwa pavarwere vakavhiyiwa gomarara rezamu pakati paNyamavhuvhu 2002 naChikunguru 2003. Varwere ava vakawanawo adjuvant endocrine therapy paCancer Hospital yeHarbin Medical University kuChina. Nguva yekutevera yaive makore 5.1. Chidzidzo chacho chakawedzera kuongororwa nehomoni receptor mamiriro uye endocrine therapy. (Kang X et al, CMAJ. 2010).
Makiyi Ekutora-aways:
Zviwanikwa kubva kuongororo zvakaratidza kuti kuwanda kwesoy isoflavones sechikamu chekudya kunogona kudzora njodzi yekudzokororazve mumashure-menopausal kenza yemazamu varwere vaive netariro kune estrogen receptor uye progesterone receptor, uye avo vaigamuchira endocrine kurapwa.
Chikafu chekudya Mushure meKenza Kuongorora!
Hapana kanzura mbiri dzakafanana. Enda pamusoro peyakajairwa nhungamiro yemunhu wese uye utore sarudzo dzakagadzirirwa nezve chikafu uye zvinowedzerwa uine chivimbo.
6. Dietary Soy Supplements uye Bele Cancer Risk mune vakadzi veFrance
Chidzidzo chakaburitswa nguva pfupi yadarika muAmerican Journal yeClinical Nutrition mu2019, chakaferefeta kushamwaridzana kuri pakati pezvekudya soy yekuwedzera kudya uye kenza yemazamu njodzi. Chidzidzo ichi chaisanganisira data revakadzi ve76,442 veFrance vanobva kuINSERM (French National Institutes for Health and Medical Research) Etude Epidemiologique aupres de Femmes de la Mutuelle Generale de l'Education Nationale (E3N) cohort. Vakadzi vakasanganisirwa muchidzidzo ichi vaive zera rinopfuura makore makumi mashanu uye vakazvarwa pakati pa50 na1925. Vakateverwa kubva muna1950 kusvika2000 paine avhareji yekutevera nguva yemakore 2011. Uye zvakare, iyo yekuwedzera yekuwedzera yekushandisa yakaongororwa yega yega 11.2-2 makore. (Touillaud M et al, Am J Kliniki Nutriti. 2019)
Vatsvakurudzi vakaona kuti pakanga pasina kubatana kwakawanda pakati pekushandisa kwazvino kana kwekare kwekudya kwesosi zvinowedzera (zvine isoflavones) uye njodzi yekenza yemazamu. Nekudaro, pavakaongorora iyo data neestrogen receptor (ER) chinzvimbo, zvakaonekwa kuti paive nenjodzi yakaderera yesrogen receptor positive (ER +) kenza yemazamu uye nenjodzi yakakwira yesrogen receptor negative (ER-) kenza yemazamu parizvino dhayeti soy kuwedzera vashandisi. Dhata zvakare yakaratidza kuti vakadzi vane nhoroondo yemhuri yekenza yemazamu vaive panjodzi yakanyanya yeEER- gomarara repazamu. Premenopausal, munguva pfupi yapfuura vakadzi uye vakadzi vane postmenopausal vasina nhoroondo yemhuri yekenza yemazamu vaive nenjodzi yakaderera yekenza yemazamu yeEER.
Makiyi Ekutora-aways:
Zvakawanikwa zvechidzidzo ichi zvinoratidza kuti kune mapato anopikisa ezvekudya zveyadhi zvinowedzera neestrogen receptor yakanaka uye ER-isina njodzi kenza yemazamu. Uye zvakare, vakadzi vane nhoroondo yemhuri yekenza yemazamu vanofanirwa kungwarira pavanotora zvekudya zveyadhi zvinowedzera.
7. Mhedzisiro yeSoy Kuwedzeredza paMazamu Kenza Njodzi Maki dzakadai seMammographic / Chipfuva Kuwanda
Chidzidzo chakaburitswa muna2015 chakaongorora mhedzisiro yesoyosi yekuwedzera pane mammographic / kuwanda kwemazamu mu66 vakamborapwa varwere vekenza yemazamu uye vakadzi makumi maviri nevatatu vane njodzi. Mammographic density, inozivikanwawo seyakawandisa mazamu, ndiyo muzana yezvinyama zvakaomarara zvezamu rese. Icho chimwe chezvinhu zvine njodzi zvakanyanya mukenza wemazamu. Chidzidzo chemakiriniki chaisanganisira vakadzi vane makore makumi matatu kusvika makumi manomwe nemashanu vaive:
- vakawanikwa vaine kenza yemazamu uye vaigona kurapwa kana kusarapwa neyakajairika yekuchengeta mahormone ekurapa kana aromatase inhibitor (AI) mwedzi mitanhatu zvisati zvaitika, pasina humbowo hwekudzokazve; kana
- vakadzi vane njodzi huru vane inozivikanwa BRCA1 / BRCA2 shanduko, kana nhoroondo yemhuri inoenderana nekenza yemazamu yenhaka.
Vatori vechikamu vakaiswa mumapoka maviri. Boka rekutanga rakagamuchira mahwendefa e soy ane 2 mg isoflavones uye boka rekutonga rakagamuchira mahwendefa e placebo ane microcrystalin cellulose. Dhijitari mammograms uye zamu MRI scans zvakawanikwa pane yekutanga (isati yawedzera) uye nemwedzi gumi nemaviri mushure mezuva nezuva 50 mg soy isoflavones piritsi kana placebo piritsi yekuwedzera. (Wu AH et al, Cancer Prev Res (Phila), 2015).
Makiyi Ekutora-aways:
Iko kuongorora kwakawana kuderera kudiki mumammographic density muzana (yakayerwa neyakaenzana yemwedzi wegumi nemaviri kusvika kumatanho ekutanga) muboka rakagamuchira soya yekuwedzera pamwe neboka rinodzora. Zvisinei, shanduko idzi hadzina kusiyana pakati pemishonga. Saizvozvowo, mhedzisiro yevarwere vegomarara repazamu uye vakadzi vane njodzi zvakanyanya vakafananidzwa. Mukupedzisa, ivo vaongorori vakataura kuti soy isoflavone yekuwedzera haina kukanganisa mammographic density.
8. Adolescent uye Adult Soy Kudya Kudya uye Bele Cancer Njodzi
Mune chidzidzo chakaburitswa muna 2009, vaongorori vakaongorora data kubva kuShanghai Vakadzi Hutano Kudzidza kuti vaongorore kusangana kwevechiri kuyaruka uye kwevakuru soy kudya kudya nekenza yemazamu njodzi. Chidzidzo ichi chaisanganisira vakadzi 73,223 veChinese vane makore ari pakati pe40-70 makore vakanyoreswa pakati pe1996 na2000. Dhata yemibvunzo-yakashandiswa kuongorora kudya kunodyiwa panguva yehukuru uye kuyaruka. 592 zviitiko zvekenza yemazamu zviitiko zvakataurwa mushure mekutevera angangoita makore manomwe. (Lee SA et al, Am J Kliniki Nutriti. 2009)
Kiyi kutora-aways:
Zvakawanikwa pakutsvagurudza zvakaratidza kuti kudya kwakawanda kwesoyy kudya kunogona kudzora njodzi yekenza yemazamu pakati pevakadzi ve premenopausal. Vakadzi vaidya huwandu hwakawanda hwezvikafu zve soy nguva dzese panguva yekuyaruka kwavo uye kuva munhu mukuru vaive nenjodzi yakadzikira yekenza yemazamu. Nekudaro, ivo havana kuwana chero hukama ne soy chikafu chinodyiwa che postmenopausal kenza yemazamu.
Chii chatinofanira kupa kubva kuZvidzidzo izvi?
Ongororo idzi dzinoratidza kuti kudya soya chikafu muhuwandu hwepakati hakuwedzere njodzi yezamu kenza. Mukuwedzera, zvishoma zvezvidzidzo zvinoratidza kuti zvokudya zve soya zvinogona kuderedza ngozi yekenza yemazamu, kunyanya muChinese / Asia vakadzi. Imwe ongororo inoratidzawo kuti mabhenefiti aya akanyanya muvakadzi vanodya chikafu chesoya nguva dzose panguva yekuyaruka kwavo uye kukura. Zvokudya zveSoy zvinogonawo kuderedza cholesterol uye kuderedza ngozi yezvirwere zvemoyo. Zvisinei, zvingasava zvakachengeteka kutora zvekudya soy zvinowedzera, kunyanya nevakadzi vane nhoroondo yemhuri yekenza yemazamu. Mukupfupisa, zvakachengeteka uye zvine hutano kutora zvine mwero zvikafu zesoya sechikamu chekudya kwedu / chikafu pane kutora zvokuwedzera. Dzivisa soy yekuwedzera yekutora kunze kwekunge yakurudzirwa nevarapi vako vezvehutano.
Chikafu chipi chaunodya uye chinowedzera iwe kutora chisarudzo chaunoita. Sarudzo yako inofanirwa kusanganisira kutarisisa kwecancer genes shanduko, iyo kenza, kurapwa kuri kuenderera uye zvinowedzerana, chero mairigeji, ruzivo rwemararamiro, huremu, kukwirira uye maitiro.
Kurongeka kwehutano kwekenza kubva kuAddon hakubvi pakutsvaga kweinternet. Iyo inoshandura sarudzo kuitirwa iwe zvichibva pane samorekuru sainzi inoitwa nemasayendisiti edu uye mainjiniya esoftware. Zvisinei kuti une hanya here nekunzwisisa iyo yepasi biochemical molecular pathways kana kwete - yekuronga kudya kwemukenza kunzwisiswa kunodiwa.
Tanga IZVOZVO nekuronga kwako kudya kunovaka muviri nekupindura mibvunzo pazita rekenza, majini masayendisiti, kurapwa kuri kuenderera uye zvinowedzerana, chero kurwara, tsika, mararamiro, boka rezera uye murume kana murume.
Hunhu Hwakakosheswa Nekamwe Kenza!
Gomarara rinoshanduka nekufamba kwenguva. Gadzirisa uye gadzirisa chikafu chako zvichibva pachiratidzo chegomarara, marapirwo, mararamiro, zvaunofarira zvekudya, allergies uye zvimwe zvinhu.
Varwere veCancer kazhinji vanofanirwa kubata zvakasiyana chemotherapy mhedzisiro izvo zvinokanganisa kwavo hupenyu hwehupenyu uye kutarisa kune dzimwe nzira dzokurapwa kwekenza kudya kwakakwana uye zvekuwedzera zvinoenderana nesainzi (Kudzivirira kufungidzira uye kusarudzika kusarudza) ndiyo yakanyanya kurongeka mushonga wekenza uye kurapwa kwakanangana nemhedzisiro.