Chemotherapy ndi zoyipa zake mu khansa

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Chemotherapy ndiye njira yayikulu yothandizira khansa komanso njira yoyamba yosankhira khansa yambiri mothandizidwa ndi malangizo azachipatala komanso umboni. Komabe, ngakhale kupita patsogolo kwachipatala ndikusintha kwa chiwerengero cha opulumuka khansa pazaka makumi angapo zapitazi, zotsatira zazifupi komanso zoyipa za chemotherapy zimakhalabe zofunika kwambiri kwa onse odwala ndi azachipatala. Kusankha zakudya zoyenera komanso zowonjezera pazakudya zitha kuthandizira kuthana ndi zovuta zina.

Chemotherapy ndi chiyani?

Chemotherapy ndi mtundu wa khansa mankhwala omwe amagwiritsa ntchito mankhwala kuti awononge maselo a khansa omwe akugawanika mofulumira. Ilinso njira yoyamba yothandizira odwala khansa ambiri mothandizidwa ndi malangizo azachipatala ndi umboni.

Chemotherapy sikunatanthauzidwe koyambirira kuti igwiritsidwe ntchito pakadali pano pochiza khansa. M'malo mwake, zidapezeka panthawi ya nkhondo yachiwiri yapadziko lonse pomwe ofufuzawo adazindikira kuti mpweya wa mpiru wa nayitrogeni wapha ma cell oyera ambiri. Izi zidalimbikitsa kafukufuku wowonjezera ngati zingaletse kukula kwa magulu ena a khansa omwe amagawika mwachangu komanso osintha. Kupyolera mu kufufuza kwina, kuyesa, ndi kuyesa kwachipatala, chemotherapy yasintha momwe iliri lero.

Mankhwala osiyanasiyana a chemotherapy ali ndi njira zosiyanasiyana zomwe zimagwiritsidwa ntchito polimbana ndi mitundu ina ya khansa. Mankhwalawa amafunsidwa motere:

• mwina asanamuchite opaleshoni kuti achepetse kukula kwa chotupa chachikulu;
• kungochepetsa kukula kwamaselo a khansa;
• kuchiza khansa yomwe yasintha ndikufalikira mbali zosiyanasiyana za thupi; kapena
• kuthetseratu ndikuyeretsa maselo onse omwe ali ndi khansa yomwe ikukula mofulumira kuti tipewe kubwerera m'tsogolo.

Masiku ano, pali mankhwala opitilira 100 omwe amalandila komanso kupezeka pamsika wama khansa osiyanasiyana. Magulu osiyanasiyana a mankhwala a chemotherapy amaphatikizapo ma alkylating agents, antimetabolites, plant alkaloids, antitumor antibiotics ndi topoisomerase inhibitors. Odwala oncologist amasankha mankhwala omwe angagwiritsidwe ntchito pochiza wodwala khansa potengera zinthu zosiyanasiyana. Izi zikuphatikiza:

• mtundu ndi gawo la khansa
• khansa
• matenda omwe alipo kale a wodwalayo
• msinkhu wa wodwala komanso thanzi labwino

Chemotherapy zoyipa

Ngakhale kupita patsogolo kwamankhwala ndikusintha kwa chiwerengero cha opulumuka khansa mzaka makumi angapo zapitazi, zoyipa zake anti-khansa chemotherapy imakhalabe vuto lalikulu kwa onse odwala komanso azachipatala. Kutengera mtundu wa mankhwalawo, chemotherapy imatha kuyambitsa zovuta zoyipa. Zotsatirazi zimatha kukhudza kwambiri moyo wa wodwala khansa.

Zotsatira Zazifupi

Chemotherapy imawononga kwambiri ma cell omwe akugawana mwachangu. Mbali zosiyanasiyana za thupi lathu momwe maselo abwinobwino amagawika pafupipafupi zimakhudzidwa kwambiri ndi chemotherapy. Tsitsi, pakamwa, khungu, matumbo ndi mafupa amakhudzidwa kwambiri ndi mankhwala a chemotherapy.

Zotsatira zakanthawi kochepa za chemotherapy zomwe zimawoneka mwa odwala khansa ndi monga:

• kupweteka tsitsi
• kunyoza ndi kusanza
• kusowa kwa njala
• kudzimbidwa kapena kutsegula m'mimba
• kutopa
• kusowa tulo 
• vuto la kupuma
• khungu limasintha
• zizindikiro ngati chimfine
• ululu
• esophagitis (kutupa kwa kum'mero ​​komwe kumayambitsa mavuto)
• zilonda mkamwa
• mavuto a impso ndi chikhodzodzo
• kuchepa kwa magazi (kuchepa kwa maselo ofiira amwazi)
• matenda
• mavuto otseka magazi
• kuchuluka kwa magazi ndi mabala
• neutropenia (chikhalidwe chifukwa cha ma neutrophils ochepa, mtundu wa maselo oyera amwazi)

Zotsatirazi zimatha kusiyanasiyana pakati pa munthu ndi munthu komanso kuchokera ku chemo kupita ku chemo. Kwa wodwala yemweyo, zotsatirapo zake zimatha kusiyanasiyana panthawi yamankhwala awo am'thupi. Zambiri mwa zotsatirazi zimakhudza thanzi komanso thanzi la odwala khansa. 

Zotsatira Zakale Zakale

Ndi kugwiritsa ntchito kwambiri mankhwala a chemotherapy m'magulu osiyanasiyana a odwala khansa, ma poizoni omwe amapezeka ndimankhwala okhazikikawa monga chemotherapies yochokera ku platinamu pitirizani kuwonjezeka. Chifukwa chake, ngakhale atapita patsogolo kwambiri kuchipatala, ambiri mwa omwe adapulumuka khansa amatha kuthana ndi zovuta zomwe zimakhalapo pambuyo pothandizidwa ndi chemotherapy, ngakhale zaka zingapo chithandizocho chitachitika. Malinga ndi National Pediatric Cancer Foundation, akuti pafupifupi 95% ya omwe adzapulumuke khansa adzakhala ndi vuto lalikulu pofika zaka 45, zomwe zitha kukhala zotsatira za chithandizo chawo choyambirira cha khansa (https: //nationalpcf.org/facts-about-childhood-cancer/). 

Kafukufuku wosiyanasiyana wazachipatala adachitidwa kwa odwala khansa ndi omwe adapulumuka mitundu yosiyanasiyana ya khansa monga khansa ya m'mawere, kansa ya Prostate ndi lymphoma kuti awone kuwopsa kwa zoyipa zomwe zingachitike chifukwa cha khansa. Kafukufuku wamankhwala akuwunika zoyipa za mankhwala a chemotherapy mwa omwe adapulumuka khansa afotokozedwa mwachidule pansipa.

Zofufuza pazotsatira zoyipa za Chemotherapy

Kuopsa kwa Khansa Yachiwiri

Ndi chithandizo chamakono cha khansa pogwiritsa ntchito chemotherapy kapena radiotherapy, ngakhale kuchuluka kwa zotupa zolimba kwasintha, chiwopsezo cha khansa yothandizidwa ndi mankhwala (imodzi mwazomwe zimachitika nthawi yayitali) zawonjezekanso. Kafukufuku wosiyanasiyana akuwonetsa kuti mankhwala ochulukirapo a chemotherapy amachulukitsa chiopsezo chopeza khansa yachiwiri atakhala opanda khansa kwakanthawi. 

Kafukufuku wopangidwa ndi National Cancer Institute adasanthula kwambiri za odwala opitilira 700,000 omwe ali ndi zotupa za khansa. Odwalawa adalandira chemotherapy kuyambira 2000-2013 ndipo adapulumuka kwa chaka chimodzi atapezeka. Anali azaka zapakati pa 1 ndi 20. Ofufuzawo adapeza kuti chiwopsezo cha chithandizo chokhudzana ndi myelodysplastic syndrome (tMDS) ndi acute myeloid leukemia (AML) "chinawonjezeka kuchoka pa 84-fold mpaka pa 1.5-fold kwa 10 mwa mitundu 22 ya khansa yolimba yomwe anafufuza" . (Morton L et al, JAMA Oncology. Disembala 20, 2018) 

Kafukufuku wina adachitidwa posachedwa ndi ofufuza ochokera ku University of Minnesota Medical School mwa opitilira khansa yaubwana ya 20,000. Omwe apulumuka adapezeka ndi khansa ali ndi zaka zosakwana 21, pakati pa 1970-1999 ndipo adalandira mankhwala a chemotherapy / radiotherapy kapena chemotherapy limodzi ndi radiation radiation. Kafukufukuyu adawonetsa kuti opulumuka omwe amathandizidwa ndi chemotherapy okha, makamaka omwe amathandizidwa ndi kuchuluka kwa platinamu ndi othandizira ma alkylating, amakhala ndi ziwopsezo za 2.8 zomwe zimawonjezera khansa yoyipa poyerekeza ndi anthu ambiri. (Turcotte LM et al, J Clin Oncol., 2019) 

Kafukufuku wina adachitidwanso ndikufalitsidwa mu 2016 omwe adayesa zambiri kuchokera kwa 3,768 azimayi khansa ya m'magazi kapena omwe adatsala ndi khansa ya sarcoma popanda mbiri ya radiotherapy pachifuwa. Omwe adapulumuka khansa amathandizidwa kale ndi kuchuluka kwa cyclophosphamide kapena anthracyclines. Kafukufukuyu adawona kuti opulumukawa adalumikizidwa kwambiri ndi chiopsezo chokhala ndi khansa ya m'mawere. (Henderson TO et al., J Clin Oncol., 2016)

Kafukufuku wina, zidapezeka kuti anthu omwe ali ndi Hodgkin's Lymphoma ali pachiwopsezo chachikulu chotenga khansa yachiwiri atalandira radiotherapy. Lymphoma ya Hodgkin ndi khansa yamitsempha yamagazi yomwe ndi gawo limodzi lama chitetezo chamthupi. (Petrakova K et al, Int J Clin Pract. 2018)

Komanso, ngakhale kuli kwakukula kwambiri koyambirira kwa azimayi omwe ali ndi khansa ya m'mawere, chiopsezo chokhala ndi zotupa zoyambilira zoyipa pambuyo pake chawonjezekanso (Wei JL et al, Int J Clin Oncol. 2019).

Kafukufukuyu akuwonetsa kuti khansa yaubwana yomwe imalandira mankhwala owonjezera a chemotherapy monga cyclophosphamide kapena anthracyclines amakumana ndi chiopsezo chowopsa cha zotsatira za khansa yotsatira.  

Kuopsa kwa Matenda a Mtima

Chotsatira china cha chemotherapy ndimatenda amtima kapena amtima. Kafukufuku wosiyanasiyana akuwonetsa kuti pali chiopsezo chowonjezeka chakulephera kwa mtima mwa omwe adapulumuka khansa ya m'mawere, zaka zitadwala koyamba khansa yawo. Congestive mtima kulephera ndichikhalidwe chomwe chimachitika pomwe mtima sungathe kupopa magazi mozungulira thupi moyenera.

Kafukufuku waposachedwa, ofufuza aku Korea adasanthula pafupipafupi zomwe zimachitika komanso zoopsa zomwe zimayambitsidwa ndi congestive mtima kulephera (CHF) mwa odwala khansa ya m'mawere omwe adapulumuka zaka zopitilira 2 atapezeka ndi khansa. Kafukufukuyu adachitika ndi National Health Information Database yaku South Korea ndipo adaphatikizapo zambiri kuchokera kwa anthu 91,227 omwe adapulumuka khansa yapakati pakati pa 2007 ndi 2013. Ofufuzawo adapeza kuti:

• Zowopsa zakulephera kwa mtima zinali zazikulu mwa omwe adapulumuka khansa ya m'mawere, makamaka kwa omwe apulumuka azaka zosakwana zaka 50, kuposa kuwongolera. 
• Opulumuka khansa omwe kale amathandizidwa ndi mankhwala a chemotherapy monga anthracyclines (epirubicin kapena doxorubicin) ndi ma taxi (docetaxel kapena paclitaxel) adawonetsa chiopsezo chachikulu cha matenda amtima (Lee J et al, Khansa, 2020). 

Pakafukufuku wina wopangidwa ndi University of Paulista State University (UNESP), ku Brazil, ofufuzawo adawunika zomwe zimawopsa chifukwa cha mavuto amtima mwa omwe adapulumuka khansa ya m'mawere. Iwo anayerekezera deta kuchokera kwa opulumuka 96 omwe anapulumuka khansa ya m'mawere omwe anali azaka zopitilira 45 ndi azimayi 192 omwe atha msambo omwe analibe khansa ya m'mawere. Kafukufukuyu adatsimikiza kuti azimayi omwe amapezeka pambuyo pa khansa ya m'mawere omwe apulumuka khansa ya m'mawere adalumikizana kwambiri ndi zoopsa zamatenda am'mimba komanso kunenepa kwambiri m'mimba poyerekeza ndi azimayi omwe atha msambo omwe alibe mbiri ya khansa ya m'mawere (Buttros DAB et al, Menopause, 2019).

Pakafukufuku wofalitsidwa ndi Dr Carolyn Larsel ndi gulu lochokera ku Mayo Clinic, United States, adasanthula zambiri kuchokera ku 900+ khansa ya m'mawere kapena odwala lymphoma ochokera ku Olmsted County, United States. Ofufuzawa adapeza kuti khansa ya m'mawere ndi odwala lymphoma anali pachiwopsezo chachikulu chakulephera kwamtima pambuyo pa chaka choyamba chodziwika chomwe chidapitilira zaka 20. Kafukufukuyu adapezanso kuti odwala omwe amathandizidwa ndi Doxorubicin anali ndi chiopsezo chowirikiza kawiri cha kulephera kwa mtima poyerekeza ndi mankhwala ena. (Carolyn Larsen et al, Journal of the American College of Cardiology, Marichi 2018)

Zotsatira izi zatsimikizira kuti mankhwala ena a khansa atha kukulitsa chiopsezo cha zovuta zoyambitsa matenda amtima mwa omwe adapulumuka khansa ngakhale zaka zingapo atapezeka ndi chithandizo.

Kuopsa kwa Matenda a M'mapapo

Matenda am'mapapo kapena zovuta zam'mapapo zimakhazikitsanso ngati zotsatira zoyipa za chemotherapy. Kafukufuku wosiyanasiyana akuwonetsa kuti opulumuka khansa ya ana amakhala ndi matenda opitilira m'mapapo / zovuta monga kukhosomola kosalekeza, mphumu komanso chibayo chobwerezabwereza akamakula ndipo chiopsezo chimakhala chachikulu akamalandira mankhwala a radiation ali aang'ono.

Pakafukufuku wofalitsidwa ndi American Cancer Society, ofufuzawo adasanthula zomwe adafufuza kuchokera ku Study Cancer Survivor Study yomwe idasanthula anthu omwe adapulumuka zaka zosachepera zisanu atapezeka ndi khansa monga khansa ya m'magazi, malignancies apakati komanso ma neuroblastomas. Kutengera ndi chidziwitso cha odwala opitilira 14,000, ofufuzawo adapeza kuti pofika zaka 45, kuchuluka kwamapapo m'mapapo kunali 29.6% ya omwe adapulumuka khansa ndi 26.5% ya abale awo. Anatsimikiza kuti zovuta zam'mapapo / m'mapapo ndizofunikira pakati pa omwe adapulumuka khansa yaubwana ndipo zimatha kukhudza zochitika zatsiku ndi tsiku. (Dietz AC et al, Khansa, 2016).

Pakafukufuku wina wopangidwa ndi ofufuza aku University of Columbia ku New York, adayesanso chimodzimodzi potengera zomwe ana 61 adakumana ndi radiation ya m'mapapo ndipo adayesedwa m'mapapo. Adapeza kulumikizana kwachindunji komwe kumawonetsa kuti kukanika kwa m'mapapo / m'mapapo kumafala pakati pa omwe apulumuka khansa ya ana omwe amalandila radiation m'mapapo ngati gawo la mankhwala awo. Ofufuzawo adawonanso kuti panali chiwopsezo chachikulu chokhala ndi vuto la m'mapapo mwanga / m'mapapo pomwe chithandizocho chidachitika ali achichepere chifukwa chakukula msinkhu (Fatima Khan et al, Advances in Radiation Oncology, 2019).

Podziwa kuopsa kwa chithandizo champhamvu ngati chemotherapy, azachipatala atha kupititsa patsogolo chithandizo cha khansa mwa ana kuti apewe zovuta zoyambazi mtsogolo. Zizindikiro za zovuta zam'mapapo zimayenera kuyang'aniridwa mosamala ndipo njira ziyenera kutetezedwa. 

Kuopsa kwa Sitiroko Yotsatira

Kufufuza kwa chidziwitso kuchokera ku kafukufuku wodziyimira payokha akuwonetsa kuti opulumuka khansa omwe adalandira mankhwala a radiation kapena mankhwala a chemotherapy atha kukhala ndi chiopsezo chowopsa cha zotsatirapo za sitiroko. 

Pakafukufuku omwe ochita kafukufuku ku South Korea adachita, adasanthula za odwala 20,707 a khansa ochokera ku Korea National Health Insurance Service National Sample Cohort database pakati pa 2002-2015. Adapeza mgwirizano wabwino wokhala ndi chiopsezo chachikulu cha odwala khansa poyerekeza ndi omwe siomwe ali ndi khansa. Chithandizo cha Chemotherapy chimagwirizanitsidwa palokha ndi chiwopsezo chowonjezeka cha sitiroko. Vutoli linali lalikulu mwa odwala khansa ya ziwalo zam'mimba, khansa yopuma komanso ena monga khansa ya m'mawere ndi khansa ya ziwalo zoberekera za abambo ndi amai. Kafukufukuyu adatsimikiza kuti chiwopsezo cha sitiroko mwa odwala khansa chinawonjezeka patatha zaka zitatu atapezeka ndi vutoli ndipo izi zidapitilira mpaka zaka 3 zotsatira. (Jang HS et al, Kutsogolo. Neurol, 7)

Kafukufuku wopangidwa ndi Xiangya School of Public Health, Central South University, China, adachita meta-kafukufuku wazaka 12 omwe adasankhidwa odziyimira payokha pakati pa 1990 mpaka 2017, ndi odwala 57,881 onse, omwe adalandira mankhwala a radiation. Kuwunikaku kunawonetsa chiopsezo chachikulu chakupwetekedwa pambuyo pake kwa omwe adapulumuka khansa omwe amalandila chithandizo cha radiation poyerekeza ndi omwe sanalandire mankhwala a radiation. Adapeza kuti chiwopsezo chake chinali chachikulu pochiza odwala omwe ali ndi Hodgkin's lymphoma ndi mutu, khosi, ubongo kapena khansa ya nasopharyngeal. Mgwirizanowu wa radiation ndi sitiroko udapezeka kuti ndiwokwera kwambiri kuposa azaka 40 poyerekeza ndi achikulire. (Huang R, et al, Front Neurol., 2019).

Zotsatira zamaphunziro azachipatala awa awonetsa chiwopsezo chachikulu chotsatira sitiroko mwa omwe adapulumuka khansa omwe kale amathandizidwa ndi radiation radiation kapena chemotherapy.

Kuopsa kwa kufooka kwa mafupa

Osteoporosis ndi njira ina yanthawi yayitali yomwe imawonekera mwa odwala khansa ndi opulumuka omwe alandila chithandizo monga chemotherapy ndi mankhwala a mahomoni. Osteoporosis ndimatenda am'mafupa omwe amachepetsedwa, ndikupangitsa fupa kukhala lofooka komanso lofooka. Kafukufuku wambiri akuwonetsa kuti odwala ndi opulumuka mitundu ya khansa monga khansa ya m'mawere, khansa ya prostate ndi lymphoma ali pachiwopsezo chowonjezeka cha kufooka kwa mafupa.

Kafukufuku wotsogozedwa ndi ofufuza ochokera ku Johns Hopkins Bloomberg School of Public Health, Baltimore, United States, adawunika kuchuluka kwa kufooka kwa mafupa monga osteoporosis ndi osteopenia mwa omwe adapulumuka khansa ya m'mawere 211. Omwe apulumuka khansa ya m'mawere amapezeka ndi khansa ali ndi zaka pafupifupi 47. Ofufuzawo anayerekezera zomwe zidapulumuka ndi omwe adapulumuka khansa ya m'mawere ndi azimayi 567 opanda khansa. Kuwunikaku kunapeza kuti panali 68% chiwopsezo chachikulu cha kufooka kwa mafupa mwa omwe adapulumuka khansa ya m'mawere poyerekeza ndi azimayi omwe alibe khansa. (Cody Ramin et al, Kafukufuku wa Khansa ya M'mawere, 2018)

Pakafukufuku wina wamankhwala, kafukufuku wochokera kwa odwala 2589 aku Danish omwe adapezeka kuti ali ndi vuto lalikulu la B-cell lymphoma kapena follicular lymphoma adasanthula. Odwala a lymphoma amathandizidwa kwambiri ndi ma steroids monga prednisolone pakati pa 2000 ndi 2012. Zambiri kuchokera kwa odwala khansa zimafaniziridwa ndi maphunziro olamulira a 12,945 kuti awunikire zomwe zimachitika pakutha kwa mafupa monga zochitika za osteoporotic. Kuwunikaku kunawonetsa kuti odwala lymphoma anali ndi chiopsezo chowonjezeka cha kutayika kwa mafupa poyerekeza ndi kuwongolera, ali ndi zaka 5 ndi zaka 10 zowerengera zowopsa zomwe akuti ndi 10.0% ndi 16.3% ya odwala lymphoma poyerekeza ndi 6.8% ndi 13.5% pakuwongolera. (Baech J et al, Leuk Lymphoma., 2020)

Zotsatira izi zikusonyeza kuti odwala khansa ndi opulumuka omwe alandila chithandizo monga aromatase inhibitors, chemotherapy, mankhwala a mahomoni ngati Tamoxifen kapena kuphatikiza awa, ali pachiwopsezo chowonjezeka chotaya mafupa.

Kuwongolera kwa Chemotherapy zoyipa posankha Zakudya Zoyenera / Zowonjezera Zakudya

Zotsatira zoyipa za chemotherapy zitha kuchepetsedwa kapena kuyang'aniridwa ndikutenga zakudya zoyenera / zowonjezera zakudya pamodzi ndi mankhwala. Zowonjezera komanso zakudya, ngati asankhidwa mwasayansi, atha kusintha mayankho a chemotherapy ndikuchepetsa zovuta zoyipa mwa odwala khansa. Komabe, kusankha kosasintha kwa zakudya ndi zowonjezera mavitamini zitha zimawonjezera zoyipa zake.

Kafukufuku wosiyanasiyana wazachipatala / maumboni omwe amathandizira phindu la chakudya / chowonjezera china pochepetsa chemo mbali zoyipa zamtundu wina wa khansa afotokozedwa mwachidule pansipa. 

1. Phunziro lachiwiri lachipatala lomwe ochita kafukufuku ku Shandong Cancer Hospital ndi Institute ku China adachita adatsimikiza kuti kuwonjezera kwa EGCG kumachepetsa kumeza zovuta / esophagitis popanda kuwononga mphamvu ya chemoradiation kapena radiation poizoni ya khansa ya m'mimba. (Xiaoling Li et al, Journal of Medicinal Food, 2019)
2. Kafukufuku wosawona omwe adachitika odwala khansa ya mutu ndi khosi adawonetsa kuti poyerekeza ndi gulu lolamulira, pafupifupi 30% ya odwala sanapeze kalasi ya 3 ya m'kamwa mucositis (zilonda mkamwa) ataphatikizidwa ndi Royal Jelly. (Miyata Y et al, Int J Mol Sci., 2018).
3. Kafukufuku wopangidwa ndi ofufuza ochokera ku Shahrekord University of Medical Science ku Iran adawonetsa kuti lycopene itha kukhala yothandiza pochepetsa zovuta chifukwa cha nephrotoxicity (mavuto a impso) a cisplatin chifukwa chokhudza zina mwa impso. (Mahmoodnia L et al, J Nephropathol., 2017)
4. Kafukufuku wamankhwala ochokera ku Yunivesite ya Tanta ku Egypt adawonetsa kugwiritsidwa ntchito kwa Mkaka waminga yogwira Silymarin pamodzi ndi Doxorubicin imathandiza ana omwe ali ndi khansa ya m'magazi (ALL) pochepetsa mtima wa Doxorubicin. (Hagag AA et al, Infect Disord Drug Target., 2019)
5. Kafukufuku m'modzi wopangidwa ndi chipatala cha Rigshospitalet ndi Herlev, ku Denmark pa 78 odwala adapeza kuti Mannitol amagwiritsa ntchito odwala khansa yamutu ndi khosi omwe amalandila mankhwala a cisplatin amatha kuchepetsa kuvulala kwa impso kwa Cisplatin (Hagerstrom E, et al, Clin Med Kuzindikira Oncol., 2019).
6. Kafukufuku wopangidwa ku Yunivesite ya Alexandria ku Egypt adapeza kuti kutenga mbewu zakuda zolemera mu Thymoquinone Pamodzi ndi chemotherapy imatha kuchepa kwa febrile neutropenia (maselo oyera oyera) mwa ana omwe ali ndi zotupa zamaubongo. (Mousa HFM et al, Child's Nervous Syst., 2017)

Kutsiliza

Mwachidule, chithandizo chaukali ndi chemotherapy chikhoza kuonjezera chiopsezo chokhala ndi zotsatira za nthawi yochepa komanso zazitali kuphatikizapo mavuto a mtima, matenda a m'mapapo, kutaya mafupa, kachiwiri. khansa ndi zikwapu ngakhale patapita zaka zingapo mankhwala. Chifukwa chake, musanayambe chithandizo, ndikofunikira kuphunzitsa odwala khansa za zovuta zomwe chithandizochi chingakhale nacho pa thanzi lawo lamtsogolo komanso moyo wawo. Kuwunika kwa chiopsezo ndi phindu la chithandizo cha khansa kwa ana ndi achinyamata kuyenera kukomera chithandizo Kuchepetsa kuchepa kwa chemotherapy ndikuganizira njira zina kapena zochiritsira zochiritsira zochepetsera zovuta zoyipa mtsogolo. Kusankha zakudya zoyenera komanso zowonjezera zowonjezera kumathandizanso kuchepetsa zovuta zina.

Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.

Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.

Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.

Odwala khansa nthawi zambiri amatha kuthana ndi zovuta zina zamankhwala am'magazi zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.

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