Mfundo
Mankhwala a Platinum chemotherapy kuphatikiza Cisplatin ndi Carboplatin, ngakhale mankhwala othandiza khansa, amadziwikanso kuti amayambitsa zovuta zoyipa, imodzi mwazo kukhala kuchepa kwakukulu kwa mchere wofunikira wa Magnesium m'thupi, womwe umabweretsa kuvulala kwa impso. Kafukufuku wazachipatala wanena kuti kugwiritsa ntchito Magnesium supplement pamodzi ndi Platinum therapy ndikothandiza polimbana ndi kuchepa komanso kuchepetsa zotsatira za chemotherapy za poizoni wa impso mu khansa.
Kugwiritsa Ntchito Platin Therapy mu Khansa
Chithandizo cha platinamu chokhala ndi mankhwala monga Cisplatin ndi Carboplatin ndi gawo la zida zolimbana ndi khansa yamakhansa ambiri kuphatikiza ovarian, khomo lachiberekero, mapapo, chikhodzodzo, testicular, khansa ya mutu ndi khosi ndi ena ambiri. Cisplatin anali mankhwala oyamba a platinamu kuvomerezedwa ngati a khansa mankhwala mu 1978 ndipo amagwiritsidwa ntchito payekha komanso kuphatikiza ndi mankhwala ena a chemotherapy. Mankhwalawa amatha kuthetsa ma cell a khansa omwe akukula mwachangu poyambitsa kupsinjika kwambiri kwa okosijeni komanso kuwonongeka kwa DNA, zomwe zimalepheretsa kubwereza ndi kukula kwawo. Komabe, kuwonongeka kwa DNA komwe kumachitika chifukwa cha mankhwala a platinamu kumakhudzanso maselo ena abwinobwino amthupi motero mankhwalawa amalumikizidwa ndi kuwonongeka komwe kumabweretsa zotsatirapo zoyipa komanso zosafunikira.
Kutha kwa Magnesium - Zotsatira zoyipa za Platinum Chemotherapy
Chimodzi mwazotsatira zoyipa zomwe zimakhudzana ndi mankhwala a Cisplatin kapena Carboplatin platinamu ndikowonongeka kwakukulu pamankhwala ofunikira a Magnesium (Mg) mthupi, zomwe zimayambitsa hypomagnesemia (Lajer H et al, Britain J Cancer, 2003). Vutoli limalumikizidwa ndi vuto la impso la cisplatin kapena carboplatin. Hypomagnesemia itha kuphatikizidwa ndi ziwonetsero zingapo zomwe zingawopseze moyo, mitsempha kapena machitidwe omwe chiwonetsero chowonjezeka cha omwe adapulumuka khansa akuwalimbana nawo, atangomaliza maphunziro awo a chemotherapy ndikukhala okhululukidwa (Velimirovic M. et al, Hosp. Yesetsani. (1995), 2017).
Phunzirani pa Mgwirizanowu pakati pa Zovuta za Magnesium mu Carboplatin Chemotherapy yathandizira Khansa ya Ovarian
Kafukufuku wochokera ku MD Anderson Cancer Center, USA, adasanthula kuphatikiza kwa zovuta za magnesium ndi hypomagnesemia mwa odwala khansa yamchiberekero omwe amathandizidwa ndi carboplatin. Adasanthula zolemba zofunikira komanso zoyeserera za labotale za 229 omwe adadwala khansa ya ovari omwe adachitidwa opareshoni ndi chithandizo cha carboplatin chemotherapy pakati pa Januware 2004 mpaka Disembala 2014 (Liu W et al, Oncologist, 2019). Adapeza kuti kupezeka kwa hypomagnesemia kwa odwala panthawi yamankhwala a carboplatin kunali kolosera zamtsogolo kwakanthawi kochepa. Izi zinali zodziyimira pawokha pakuchepa kwa chotupa mwa odwala khansa yapamwambayi.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Mankhwala a Magnesium Amagwiritsa Ntchito Platinum Chemotherapy
Kugwiritsa ntchito zowonjezera za Magnesium panthawi ya Platinum mankhwala mu khansa idawunikidwa m'maphunziro azachipatala ndipo yawonetsa phindu. Pakuyesa kofananira kosasinthika, kotseguka kochitidwa ku Iran University of Medical Science ku Tehran, oral magnesium oxide supplementation to Cisplatin therapy mwa odwala 62 achikulire omwe ali ndi khansa ya khansa ya m'magazi omwe adangopezeka kumene. Panali odwala 31 mu gulu lothandizira omwe anapatsidwa Mg supplementation pamodzi ndi Cisplatin ndi 31 mu gulu lolamulira popanda zowonjezera. Iwo adapeza kuti kuchepa kwa ma Mg mu gulu lolamulira kunali kofunika kwambiri. Hypomagnesemia inawoneka mu 10.7% yokha ya gulu lothandizira motsutsana ndi 23.1% mu gulu lolamulira (Zarif Yeganeh M et al, Iran J Zaumoyo Pagulu, 2016). Kafukufuku wina wopangidwa ndi gulu la ku Japan adatsimikiziranso kuti kuyambiranso ndi Mg supplementation isanakwane mankhwala a Cisplatin adachepetsa kwambiri Cisplatin yomwe idayambitsa poizoni wa impso (14.2 motsutsana ndi 39.7%) mwa odwala khansa ya thoracic. (Yoshida T. et al, Japan J Clin Oncol, 2014).
Kutsiliza
Khansara ikapanda kuthandizidwa ikhoza kupha, ndipo njira za chemotherapy ngakhale zili ndi zovuta zosiyanasiyana komanso zovuta zomwe zimakhala ndi zotsatirapo zoyipa, ziyenera kugwiritsidwa ntchito kuthana ndi matendawa. Chifukwa chake, limodzi ndi njira zochepetsera kuopsa kwa zotsatirapo za mankhwala a chemotherapy, monga kuwonjezera pa Mg isanayambe komanso panthawi ya platinamu, khansa Odwala amathanso kudya zakudya zomwe zili ndi Magnesium monga nthangala za Dzungu, ma almond, oatmeal, tofu, sipinachi, nthochi, mapeyala, chokoleti chakuda ndi zina kuti zithandizire kupititsa patsogolo michere ndi michere yomwe ikusowa ndi zachilengedwe, zomwe zimatengedwa mosavuta ndi thupi. Njira yophatikizira yophatikizira chithandizo chamankhwala a chemotherapy pamodzi ndi zowonjezera komanso zofananira mwasayansi, mchere, ndi mavitamini, komanso zakudya zopatsa thanzi, ndizofunikira kuti pakhale mwayi wopambana kwa odwala khansa!
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kulosera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe khansa ndi zotsatira zake zokhudzana ndi chithandizo.