Kuopsa kwa Khansa Yotsatira Omwe Amapulumuka Khansa Yaubwana

Mfundo

Khansa za ana monga khansa ya m'magazi yomwe imathandizidwa ndi kuchuluka kwa chemotherapy monga cyclophosphamides ndi anthracyclines, imakumana ndi chiopsezo chowonjezeka chokhala ndi khansa yotsatira / yachiwiri. Khansa Yachiwiri / Yachiwiri mwa omwe adapulumuka khansa ndiofala mankhwala a chemotherapy a nthawi yayitali.

Khansa Za Ana

Khansara ya ubwana imapezeka mwa ana, achinyamata ndi achinyamata. Khansara yofala kwambiri mwa ana ndi leukemia, khansa ya m'magazi. Mitundu ina ya khansa monga lymphoma, zotupa za muubongo, sarcoma ndi zotupa zina zolimba zimathanso kuchitika. Chifukwa cha chithandizo chowongolera, pali opitilira 80% a khansa yaubwana ku US. Chithandizo chimadalira mtundu wa khansara koma zingaphatikizepo opaleshoni, mankhwala amphamvu, chithandizo cha radiation komanso posachedwapa ngakhale immunotherapy. Komabe, malinga ndi National Pediatric Cancer Foundation, akuyerekeza kuti opitilira 95% opulumuka khansa ali ana adzakhala ndi vuto lalikulu lokhudzana ndi thanzi akafika zaka 45, zomwe zitha kukhala zotsatira za chithandizo chawo choyambirira cha khansa.https://nationalpcf.org/facts-about-childhood-cancer/).

Khansa Yachiwiri mwa Omwe Amapulumuka Khansa Yaubwana

Pokhala ndi anthu ambiri opulumuka khansa, ofufuza ochokera ku Yunivesite ya Minnesota Medical School adasanthula kuyanjana kwa omwe adapulumuka khansa omwe amathandizidwa ndi chemotherapy ndimatenda a zilonda zoyipa (SMN) ngati gawo la omwe adapulumuka khansa yophunzira (Turcotte LM et al, J Clin Oncol., 2019). Adawunika ma SMN mwa omwe adapulumuka omwe adapezeka ndi khansa asanakwanitse zaka 21, pakati pa 1970-1999. Mfundo zazikuluzikulu za anthu owerengerawa ndi zomwe apeza pakuwunika kwawo ndi izi:

• Zaka zapakati pazomwe amapezeka ndi zaka 7ye ndipo zaka zapakatikati pomaliza kutsatira zinali zaka 31.8.
• Adasanthula opulumuka ali mwana opitilira 20,000 omwe amathandizidwa ndi chemotherapy yokha, chemotherapy limodzi ndi radiation radiation, radiation radiation yokha kapena ayi.
• Omwe adapulumuka paubwana omwe amathandizidwa ndi chemotherapy okha anali ndi chiopsezo chowonjezeka cha SMN 2.8.
• Kuchuluka kwa kuchuluka kwa SMN kunali kwakukulu mwa omwe anapulumuka paubwana omwe amalandila mankhwala a platinamu. Kuphatikiza apo, kwa alkylating agents (Mwachitsanzo. Cyclophosphamide) ndi anthracyclines (mwachitsanzo. Doxorubicin), panali ubale woyankha pakati pa kuchuluka kwa mankhwala a chemotherapy ndi kuchuluka kwa khansa ya m'mawere.

Kuopsa kwa Khansa Yachifuwa Yachiwiri Yoyamba M'magazi a m'magazi kapena Opulumuka a Sarcoma

Kuwunikanso kwina koyambirira ngati gawo la omwe adapulumuka khansa yapabanja omwe adaphatikizira 3,768 azimayi khansa ya m'magazi kapena khansa ya sarcoma Opulumuka omwe amathandizidwa ndi kuchuluka kwa chemotherapy monga cyclophosphamide kapena anthracyclines, zidapezeka kuti zimalumikizidwa kwambiri ndi chiopsezo chokhala ndi khansa ya m'mawere yachiwiri / yachiwiri. Panali khola la 5.3 ndi khola la 4.1 chiopsezo chowonjezeka chokhala ndi khansa yachiwiri yapachiyambi / sekondale m'ma sarcoma ndi omwe adapulumuka khansa ya m'magazi motsatana. (Henderson TO et al., J Clin Oncol., 2016)

Kuopsa kwa Khansa Yapakhungu Yapafupipafupi Omwe Amapulumuka Khansa ya Ana omwe nthawi ina adalandira Radiotherapy

Malinga ndi zomwe zapeza kuchokera ku kafukufuku wina wotchedwa DCOG-LATER cohort study yomwe inaphatikizapo 5843 Dutch opulumuka khansa ya ana omwe adapezeka ndi mitundu yosiyanasiyana ya khansa. khansa Pakati pa 1963 ndi 2001, opulumuka omwe adachiritsidwapo ndi radiotherapy anali ndi chiopsezo chowonjezereka cha khansa yapakhungu yachiwiri Kafukufukuyu adapeza kuti pafupifupi 30 kuchuluka kwa chiopsezo cha basal cell carcinomas mwa opulumukawa. Izi zinkadaliranso kukula kwa khungu lomwe limawonekera panthawi ya chithandizo. (Jop C Teepen et al, J Natl Cancer Inst., 2019)

Kutsiliza

Mwachidule, opulumuka khansa yaubwana omwe adalandira mankhwala ochulukirapo a chemotherapy monga cyclophosphamide kapena anthracyclines a khansa ngati khansa ya m'magazi ali pachiwopsezo chotenga khansa yachiwiri / yachiwiri (zotsatira zanthawi yayitali ya chemotherapy). Choncho, kusanthula chiopsezo-phindu la khansa Chithandizo cha ana ndi achichepere chiyenera kulimbikitsa chithandizo chochepa cha mankhwala amphamvu a chemotherapy ndi kuganizira za njira zina zochizira pofuna kuchepetsa chiopsezo chotenga khansa yoopsa mtsogolomo.

Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.

Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.

Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.

Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.

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