Hoʻonui i ka makaʻu o nā maʻi puʻuwai i nā mea ola maʻi umauma

o ka Naauao

Aia ka nui o ka makaʻu ʻole o ka puʻuwai / maʻi i nā mea i pakele i ka maʻi ʻaʻai umauma, mau makahiki ma hope o ka ʻike mua a me ka mālama ʻana i kā lākou maʻi ʻaʻa (hopena hopena chemotherapy lōʻihi). ʻO ka maʻi kanulau Pono e aʻo ʻia nā mea maʻi i nā hopena maikaʻi ʻole Ka maʻi 'aʻai ʻO nā lāʻau lapaʻau e like me ka radiotherapy a me ka chemotherapy hiki ke loaʻa i ko lākou olakino cardiovascular.

Hoʻohālikelike ʻia ka maʻi ʻaʻai umauma ke kumu ʻelua o ke kumu o ka make ʻana o ka maʻi ʻaʻai i nā wahine ma 2020. Me nā holomua o ka mālama ʻana i nā lāʻau lapaʻau a me ka ʻike mua ʻana, ua iho mai ka nui o ka make ʻana o ka maʻi ʻaʻai umauma e 40% mai 1989 a 2017 a hoʻonui nui i ka helu -ʻo nā mea pakele o ka maʻi kanesa maʻi (American Cancer Society, 2020). Eia nō naʻe, hōʻike nā noiʻi ʻokoʻa i ka hoʻonui ʻia o ka makaʻu o ka ola e pili ana i ka mālama ʻana e hoʻoweliweli nei i nā maʻi i nā mea ola i ka maʻi ʻaʻai, he mau makahiki ma hope o ka ʻike mua a me ka lāʻau. Nui nā hōʻike o nā maʻi maʻi ʻole e like me ka maʻi puʻuwai a me ka maʻi cerebrovascular e hāʻawi ana i ka nui o nā make o nā maʻi maʻi maʻi maʻi / nā mea ola, i mālama mua ʻia me radiotherapy a chemotherapy (Bansod S et al, Nānā i ka maʻi ʻaʻai Res. 2020; Ahmed M. Afifi et al, Ka maʻi ʻaʻai, 2020).

ʻO nā haʻawina e hōʻike ana i ka hoʻonui ʻia o nā maʻi puʻuwai ma nā mea ola maʻi umauma

Me ka hoʻonui nui ʻana o ka umauma Ka maʻi 'aʻai ʻO nā mea noiʻi Korea mai ka SMARTSHIP Group (Study of Multi-Disciplinary Teamwork for Breast Cancer Survivorship), ua alakaʻi i ka ʻāina holoʻokoʻa, kahi noiʻi retrospective e nānā i ke alapine o ka hanana a me nā mea pilikia e pili ana me ka congestive heart failure (CHF) i nā maʻi maʻi maʻi umauma i ola. ʻoi aku ma mua o 2 mau makahiki ma hope o ka ʻike ʻana i ka maʻi kanesa (Lee J et al, Ka maʻi ʻaʻai, 2020). ʻO ke kūpikipiki ʻole o ka puʻuwai kahi kūlana maʻi mau i hiki ke hiki ʻole i ka puʻuwai ke pauma pono i ke koko a puni ke kino. Ua mālama ʻia ke aʻo ʻana me ka National Health Data Database o Kōlea Hema a ua hoʻopili ʻia ka ʻikepili mai ka nui o nā maʻi i loaʻa i ka maʻi umauma 91,227 a me nā kaohi 273,681 ma waena o Ianuali 2007 a me Kekemapa 2013. nā mea pakele, keu hoʻi i nā mea pakele o ka poʻe ʻōpio ma mua o 50 mau makahiki, ma mua o nā kaohi. Ua ʻike pū lākou i nā mea pakele maʻi i mālama mua ʻia me nā lāʻau chemotherapy e like me anthracyclines (epirubicin a i ʻole doxorubicin) a me nā taxan (docetaxel a i ʻole paclitaxel) i hōʻike i kahi kiʻekiʻe o ka maʻi puʻuwai (Lee J et al, Ka maʻi ʻaʻai, 2020).

I loko o kahi noi ʻē aʻe i paʻi ʻia e nā mea noiʻi mai ka Paulista State University (UNESP), Sao Paulo, Brazil, ua hoʻohālikelike lākou i ka umauma 96 postmenopausal nā mea pakele maʻi ʻaʻai ʻoi aku ka ʻelemakule ma mua o 45 mau makahiki me 192 mau wahine postmenopausal i loaʻa ʻole i ka maʻi ʻaʻai umauma, e loiloi ai i nā pilikia e pili ana i nā pilikia puʻuwai i nā poʻe i loaʻa i ka maʻi ʻaʻai umauma hope. Ua hoʻoholo nā kānaka noiʻi he ʻoi aku ka ikaika o ka hui ʻana o nā wahine postmenopausal ka mea i pakele i ka maʻi ʻaʻai umauma me nā mea pilikia no ka maʻi puʻuwai a hoʻonui i ka momona o ka ʻōpū i ka hoʻohālikelike ʻia me nā wahine postmenopausal me ka ʻole o ka mōʻaukala umauma (Buttros DAB et al, Menopause, 2019).

Wahi a kahi noiʻi i paʻi ʻia e Dr Carolyn Larsel a me ka hui mai Mayo Clinic, Rochester, ʻAmelika Hui Pū ʻIa, e pili ana i ka maʻi ʻaʻai umauma 900+ a i ʻole nā ​​mea maʻi lymphoma mai Olmsted County, MN, ʻAmelika Hui Pū ʻIa, ua ʻike ʻia ka maʻi nui ʻana o ka maʻi ʻaʻai a me nā maʻi lymphoma. hoʻonui i ka makaʻu ʻole o ka puʻuwai ma hope o ka makahiki mua o ka hōʻoia ʻana i hoʻomau ʻia a 20 mau makahiki. Hoʻohui ʻia, ua pālua ka poʻe maʻi i mālama ʻia me Doxorubicin i ka hopena o ka puʻuwai puʻuwai ke hoʻohālikelike ʻia me nā ʻano lāʻau ʻē aʻe (Carolyn Larsen et al, Ka Nūpepa o ka American College of Cardiology, Malaki 2018).

Hoʻokumu kēia mau ʻike i ka ʻoiaʻiʻo hiki i kekahi mau lāʻau lapaʻau maʻi maʻi umauma ke hoʻonui i ka pilikia o ka ulu ʻana i nā pilikia o ka naʻau a hiki i kekahi mau makahiki ma hope o ka mālama ʻana (ka hopena ʻaoʻao chemotherapy lōʻihi). ʻO ka laina lalo, pono e aʻo ʻia nā poʻe maʻi maʻi maʻi umauma e pili ana i nā hopena maikaʻi ʻole o ka nui o nā lāʻau lapaʻau i kēia manawa i ko lākou olakino cardiovascular. ʻO nā lāʻau chemo like ʻole i hoʻohana ʻia no ka maʻi maʻi umauma hiki ke ʻona i ka puʻuwai a hoʻemi i ka hiki ʻana o ka puʻuwai puʻuwai aʻo ka radiation a me nā lāʻau lapaʻau ʻē aʻe hiki ke alakaʻi i ka ʻeha o ka ʻiʻo o ka puʻuwai, i ka hopena i nā pilikia puʻuwai koʻikoʻi. No laila, i ka wā a ma hope o ka mālama ʻana i ka maʻi kanesa o ka umauma, pono e nānā mau i ke olakino ākea o nā wahine i ʻike ʻia me ka umauma. Ka maʻi 'aʻai a e nānā i nā hōʻailona o ka pau ʻole o ka naʻau.

He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.

ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.

E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.

ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy kahi e hoʻopili ai i ko lākou ola o ke ola a nānā i nā hoʻoponopono ʻokoʻa no ka maʻi ʻaʻai. Lawe ana i ka ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.

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