Amaphuzu avelele
Ucwaningo lwe-open-lebula, lwesikhungo esisodwa, lwesigaba I olwenziwa abacwaningi base-Japan luphakamise ukuthi umthamo wansuku zonke we-12 g ye-GBS-01, equkethe cishe i-4g burdock extract ecebile nge-arctigenin, ingase iphephe ngokomtholampilo futhi ingase ibe nezinzuzo ezingaba khona iziguli ezine-pancreas ethuthukisiwe umdlavuza i-refractory ekwelashweni kwe-Gemcitabine. Kodwa-ke, izivivinyo ezinkulu ezichazwe kahle ziyadingeka ukuze kutholwe le miphumela.
IBurdock nezakhi zayo ezisebenzayo
I-Arctium lappa, eyaziwa kakhulu njenge-burdock, isitshalo esingapheli esidabuka e-Asia naseYurophu. IBurdock manje isiyathandwa emhlabeni wonke futhi iyalinywa futhi isetshenziswe njengemifino ezingxenyeni eziningi zomhlaba. Izimpande, amaqabunga, nembewu yalesi sitshalo kusetshenziswa emithini yendabuko yamaShayina njengekhambi lezifo ezahlukahlukene. Izimpande zeBurdock zigcwele ama-antioxidants futhi kubhekwa nokuthi zinemiphumela yokulwa nomdlavuza.
Izifundo ezahlukahlukene zangaphambilini zaphakamisa ukuthi i-burdock ingaba nezakhi ezilwa nokuvuvukala, i-antibacterial, antidiabetic, antiulcerogenic, hepatoprotective, kanye ne-anticancer. Izakhi eziyinhloko zokukhishwa kwe-burdock zifaka okuphuma ku-caffeoylquinic acid, ama-lignans nama-flavonoid ahlukahlukene.
Amaqabunga e-burdock ikakhulukazi aqukethe izinhlobo ezimbili zama-lignans:
- I-Arctiin
- I-Arctigenin
Ngaphandle kwalokhu, i-phenolic acid, i-quercetin, i-quercitrin ne-luteolin nayo ingatholakala emaqabungeni e-burdock.
Imbewu yeBurdock iqukethe ama-phenolic acid afana neCaffeic acid, Chlorogenic acid kanye neCynarin.
Izakhi eziyinhloko ezisebenzayo ezimpandeni zeBurdock yi-Arctiin, i-Luteolin ne-Quercetin rhamnoside engabangelwa yimiphumela yabo yokulwa nomdlavuza.
Ukusetshenziswa Okusetshenzisiwe Kwezikhishwe zeBurdock
IBurdock isetshenziswe kabanzi kuMuthi Wendabuko WamaShayina ngezinhloso ezilandelayo, noma kungekho bufakazi bemitholampilo obusekela ukusetshenziswa kwayo kweziningi zalezi zimo:
- Ukuhlanza igazi
- Ukunciphisa umfutho wegazi ophezulu
- Ukunciphisa i-gout
- Ukunciphisa i-hepatitis
- Ukunciphisa izifo ezifakwayo
- Ukunciphisa ushukela wegazi ezigulini ezinesifo sikashukela
- Ukwelapha ukuphazamiseka kwesikhumba njenge-eczema ne-psoriasis
- Ukunciphisa imibimbi
- Ukwelapha ukuphazamiseka kokuvuvukala
- Ukwelapha i-AIDS
- Ukwelapha Umdlavuza
- Njengomchamo
- Njengeti le-antipyretic lokwelapha umkhuhlane
Ukudla Okufanele Ukudla Ngemuva Kokuxilongwa Komdlavuza!
Akukho mdlavuza owodwa ofanayo. Dlulela ngale kwemihlahlandlela ejwayelekile yokudla kuwo wonke umuntu futhi wenze izinqumo ezenziwe ngezifiso ngokudla nezithasiselo ngokuzethemba.
Ngabe iBurdock Extracts Izosiza iziguli ezinomdlavuza wePancreatic eziphikisa iGemcitabine?
Ngokusho kwe-American Cancer Society, umdlavuza we-pancreatic ungowesishiyagalolunye ovame kakhulu umdlavuza kwabesifazane kanye nomdlavuza weshumi ovame kakhulu kwabesilisa futhi ubangela u-7% wabo bonke ababulawa umdlavuza.
Futhi kuyimbangela yesine ehamba phambili yokufa komdlavuza kwabesilisa nabesifazane.
IGemcitabine iyi-ejenti yokuqala ejwayelekile yamakhemikhali yokwelashwa komdlavuza wepancreatic. Kodwa-ke, i-pancreatic cancer microenvelo yaziwa kahle ukuthi ibonakaliswa yi-hypoxia ebucayi, isimo lapho umzimba uncishwa ukutholakala okwanele komoya-mpilo ezingeni lezicubu, nokuncishwa kwezakhi, ikakhulukazi i-glucose. I-Hypoxia ithuthukisa ukuphikiswa kwe-chemoressa ngokumelene ne-gemcitabine, ngaleyo ndlela kunciphise izinzuzo zale chemotherapy.
Ngakho-ke, abacwaningi abavela eNational Cancer Center Hospital East, Meiji Pharmaceutical University, National Cancer Center, Kracie Pharma, Ltd. eToyama, naseTokyo University of Science, eJapane bahlolisise izinto ezahlukahlukene ezinganciphisa ukubekezelelana kwamangqamuzana omdlavuza kube yindlala yeglucose futhi i-hypoxia, ne-arctigenin ekhonjiwe, okuyinhlanganisela eyisihluthulelo etholakala ezikhishwe eBurdock, njengenhlanganisela engcono kakhulu yokhetho lokuvivinywa komtholampilo, ngenxa yomsebenzi wayo we-antitumor obonwe ezinhlobonhlobo eziningi zomdlavuza namaphrofayli anele okuphepha lapho unikezwa ngemithamo kuze kube izikhathi eziyi-100 nsuku zonke umthamo odingekayo ekusebenzeni kwe-antitumor kumagundane. (UMasafumi Ikeda et al, Cancer Sci., 2016)
Abacwaningi basebenzise isidakamizwa somlomo i-GBS-01, isithelo se-Burdock, esicebile nge-arctigenin, ezigulini eziyi-15 ezine-pancreatic ethuthukisiwe. umdlavuza i-refractory ku-gemcitabine. Ocwaningweni, baphenya umthamo omkhulu obekezeleleke we-GBS-01 futhi babheka ubuthi obukhawulela Umthamo. I-Dose-limiting toxicities (DLTs) ibhekisela ekubonakaleni kwebanga lesi-4 lobuthi be-hematological/blood kanye nobuthi bebanga lesi-3 noma le-4 obungeyona eye-hematological/igazi phakathi nezinsuku zokuqala ezingama-28 zokwelashwa.
Ocwaningweni, bathole ukuthi azikho izimpawu zokuthi ubuthi begazi bebanga lesi-4 no-grade 3 noma 4 onobuthi obungelona igazi kunoma yiziphi iziguli ezibhalisile, kunoma yimiphi imithamo emithathu esetshenzisiwe (nsuku zonke u-3.0 g, 7.5 g noma u-12.0 g) . Kodwa-ke, ubuthi obuncane babonwa njengokukhuphuka kwe-serum γ ‐ glutamyl transpeptidase, ukwanda kweglucose yegazi, kanye nokwanda kwe-serum total bilirubin.
Ucwaningo lunqume umthamo onconyiwe we-GBS-01, okukhishwe okunothe ku-arctigenin kusuka eBurdock, ukuthi kube yi-12.0 g nsuku zonke, ngoba awekho ama-DLTs abonwe kunoma yimaphi amazinga amathathu omthamo. Umthamo wansuku zonke we-12.0 g GBS-01 wawucishe ulingane no-4.0 g we-burdock wezithelo.
Ngaphandle kweziguli ezidle okukhishwe eBurdock, iziguli ezi-4 zinezifo ezizinzile kanti i-1 ikhombise ukuphendula okuyingxenye ngesikhathi sokubuka. Ukucacisa, izinga lokuphendula lalingu-6.7% kanti izinga lokulawulwa kwezifo lalingu-33.3%. Ucwaningo luphinde lwathola ukuthi ukuqhubeka kokuphila okuphakathi nokukhululekile kweziguli kwakuyizinyanga eziyi-1.1 nezinyanga eziyi-5.7, ngokulandelana.
Isiphetho
Ama-extracts nezimpande ze-Burdock abhekwa njenge-anti-inflammatory, antibacterial, antidiabetic, antiulcerogenic, hepatoprotective, and anti-cancer properties. Ucwaningo lwango-2016 lwesigaba I somtholampilo olwenziwa abacwaningi baseJapan luphakamise ukuthi umthamo wansuku zonke we-GBS-12 (oqukethe cishe u-01 g wezithelo ze-burdock ocebile nge-arctigenin) ungase uphephe ngokomtholampilo futhi ube nezinzuzo ezingaba khona ezigulini ezine-pancreas ethuthukisiwe. zomdlavuza i-refractory ekwelashweni kwe-Gemcitabine. Kodwa-ke, izivivinyo ezinkulu ezichazwe kahle ziyadingeka ukuthola lokhu okutholakele, ngaphambi kokuncoma ukusetshenziswa kwe-arctigenin ezigulini ezinomdlavuza we-pancreatic.
Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.
Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.
Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.
Ukudla Okungokwakho Komdlavuza!
Umdlavuza uyashintsha ngokuhamba kwesikhathi. Enza ngendlela oyifisayo futhi uguqule umsoco wakho ngokusekelwe kunkomba yomdlavuza, ukwelashwa, indlela yokuphila, okuncamelayo kokudla, izinto ezingakuphathi kahle nezinye izici.
Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.