Amaphuzu avelele
Ucwaningo lwangaphambi komtholampilo kumangqamuzana omdlavuza wesibeletho, wesibeletho kanye nomdlavuza webele lubonise ukuthi ukukhishwa kwesitshalo se-neem (izithako ze-neem extract), ngokuvamile esetshenziswa emithini ye-Ayurvedic, kunezakhiwo/izinzuzo zokulwa nomdlavuza. Ngokuhlanganiswa ne-Cisplatin, izithasiselo zokukhishwa kwe-neem zathuthukisa i-cytotoxicity futhi zakwazi nokunciphisa ubuthi obuphakathi kwe-cisplatin bezinso nesibindi kumamodeli ezilwane. Izifundo zomtholampilo zokukhishwa kwe-neem ezigulini ezinomdlavuza ziyashoda, kodwa izithasiselo ze-neem extract zibonakala ziyikhambi lemvelo elingase libe khona umdlavuza.
Umdlavuza Wabesifazane
Umdlavuza we-gynecological uhlanganisa owomlomo wesibeletho, we-ovary nowebele zomdlavuza okuyizimbangela ezinkulu zokugula nokufa kwabesifazane emhlabeni jikelele. Umdlavuza Womlomo wesibeletho uhlotshaniswa kakhulu nesifo se-human papilloma virus (HPV), ngaphandle kwezinye izici eziyingozi, futhi uhlasela abesifazane abasebasha phakathi kweminyaka engama-30 nengama-40. Umdlavuza wesibeletho uhlasela abesifazane abangaphezu kuka-200,000 emhlabeni jikelele futhi unesimo esibi lapho uvame ukutholakala ngokuhamba kwesikhathi lesi sifo esisabalele kwezinye izingxenye zomzimba. Umdlavuza webele umdlavuza ovame kakhulu kwabesifazane abanesimo esingcono kancane kunomdlavuza wesibeletho nowomlomo wesibeletho. Kodwa-ke, noma yikuphi ukuxilongwa komdlavuza kuza nokwesaba nokukhathazeka ngemiphumela ezayo kanye nesifiso sokwenza konke okusemandleni ukulwa nesifo.
Inketho eyodwa iziguli eziningi ezinomdlavuza kanye nabathandekayo bazo abakubukayo ukuthatha izithasiselo zemithi nezemvelo ezinezakhiwo zokulwa nomdlavuza, ezingaqinisa amasosha omzimba, futhi zisize ukubhekana nemiphumela engemihle yemithi yokwelapha ngamakhemikhali enqunyiwe. Ucwaningo oluningi lwe umdlavuza iziguli kuzo zonke izikhungo zezokwelapha ezahlukene zinqume ukuthi u-60-80% weziguli ezinomdlavuza nabasindile basebenzisa uhlobo oluthile lwesithasiselo semvelo. (UJudson PL et al, I-Integrated Cancer Ther., 2017; I-Cancer Research UK) Isengezo esisodwa sesitshalo esinemininingwane eminingi yesayensi kuzakhiwo zaso zokulwa nomdlavuza yisicashunwa I-Azadirachta indica (Neem), isitshalo somuthi esidabuka eNdiya (UMoga MA et al, Int. UJ Mol Sci, 2018; UHao F et al, Biochim Biophys Acta, 2014). Okukhishwa kumagxolo, imbewu, amaqabunga, izimbali kanye nezithelo zesitshalo se-neem kusetshenziswe ngokwesiko emithini ye-Ayurveda, i-Unani kanye ne-homeopathic ngezindawo zayo eziningi zokwelapha.
Ukudla Okufanele Ukudla Ngemuva Kokuxilongwa Komdlavuza!
Akukho mdlavuza owodwa ofanayo. Dlulela ngale kwemihlahlandlela ejwayelekile yokudla kuwo wonke umuntu futhi wenze izinqumo ezenziwe ngezifiso ngokudla nezithasiselo ngokuzethemba.
Izakhiwo Zokulwa Nomdlavuza / Izinzuzo Zezithasiselo Zokukhishwa Kwe-Neem
Izindlela ezibalulekile zomsebenzi wokulwa nomdlavuza wezithako ezisebenzayo ekukhishweni kwe-neem zibandakanya ukukhulisa ubuthi bengqamuzana lomdlavuza ngokulawula indawo ezungezile ezungezile, kanye nokulawula ukunikezwa kwezakhi kuthumba ngokuvimbela imithambo yegazi emisha ukuthi yakhe isimila esikhulayo. Ucwaningo lwesayensi lubonise ukuthi ukukhishwa kwe-neem kungavimba i-vascular endothelial growth factor (VEGF) edingekayo ukuze kuhlume imithambo yegazi emisha edingekayo ekukhuleni kwesimila (Mahapatra S et al, Evid. Based Complement Alternat. Med., 2012). Izifundo ezinhlotsheni eziningi ezahlukene ze umdlavuza amaseli abonise umsebenzi we-cytotoxic we-neem ekhishwe kanye nezinhloso eziningi nezindlela ezilamula umthelela wokwelapha we-neem (Hao F et al, Biochim Biophys Acta, 2014).
Izithasiselo ze-Neem Extract zingagcwalisa i-Cisplatin Chemotherapy ku-Gynecologic Cancer:
Ucwaningo lokuhlola luhlolisise umphumela wezithasiselo ze-neem ezikhipha amangqamuzana omdlavuza we-ovarian, webele nowesibeletho, okukhombisa ukuthi i-neem ayikhiphanga nje kuphela ukwanda kwamaseli omdlavuza, kepha ngokuhlangana neCisplatin, i-chemotherapy esetshenziswa kakhulu kulezi umdlavuza, izengezo zokukhishwa kwe-neem zithuthukise i-cytotoxicity yeCisplatin (Kamath SG et al, Int. J Gynecol. Cancer, 2009; Sharma C et al, J Oncol. 2014). Ngokwengeziwe izifundo ezinhlobonhlobo zezilwane zale mdlavuza (i-ovarian, ibele kanye nomdlavuza womlomo wesibeletho) zikhombisile nokuthi izithasiselo zokukhishwa kwe-neem zinganciphisa ubuthi bezinso nesibindi obudalwa yiCisplatin (Moneim, AEA et al, Biol. Med. Res. Int. Int. , 2014; Shareef M et al, Matrix Sci. Med., 2018). Lezi zifundo ziphakamisa ukuthi ukukhishwa kwe-neem kunganikeza izinzuzo zokwenza ngcono impendulo yamakhemikhali kuGynecological Cancer.
Isexwayiso ngokusebenzisa i-Neem Extract Supplements
Ngemiphumela ezuzisayo yesengezo sokukhishwa kwe-neem, umuntu futhi kudingeka aqaphele ngokusebenzisa lokhu ngaphandle kokubonisana nodokotela. E-US, i-azadirachtin, isithako esisebenzayo sokukhishwa kwe-neem, isetshenziswa njengesibulala-zinambuzane esingesona ubuthi. Umthamo nokwakheka kwezithako zokukhishwa kwe-neem kubalulekile ekutholeni inzuzo efanele, futhi umthamo ophakeme kakhulu we-15 mg / kg kubantu ungaba nobuthi (UBoeke SJ et al, Ethnopharmacol, 2004).
Ngokufingqa, izinzuzo zokusebenzisa izithasiselo ze-neem zokukhipha umdlavuza we-gynecological zisekelwa yizifundo eziningi zokuhlola ezinhlobonhlobo zezifo ezifanayo njengoba zisetshenziselwa ukuhlola imithi evunyelwe. Ukuqondwa kwesayensi ngezindlela zayo zokulwa nomdlavuza kunqunyiwe. Kepha igebe elilodwa elibalulekile elilahlekile ukungabi khona kwemininingwane yomtholampilo ezifundweni zabantu ezingasivumela ukuthi sisebenzise isengezo sokukhishwa kwe-neem njengengxenye ye- Ukudla kweziguli ezinomdlavuza, ikhambi lemvelo elingase libe khona umdlavuza, ngokuzethemba okwengeziwe nangokukhululeka.
Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.
Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.
Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.
Ukudla Okungokwakho Komdlavuza!
Umdlavuza uyashintsha ngokuhamba kwesikhathi. Enza ngendlela oyifisayo futhi uguqule umsoco wakho ngokusekelwe kunkomba yomdlavuza, ukwelashwa, indlela yokuphila, okuncamelayo kokudla, izinto ezingakuphathi kahle nezinye izici.
Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.