Amaphuzu avelele
Ekuhlaziyweni kwakamuva kwedatha evela kwabesilisa nabesifazane e-United States, ababambe iqhaza ocwaningweni olukhulu, lwesikhathi eside, abacwaningi bahlole ukuhlobana phakathi kwe-retinoid yemvelo ye-Vitamin A (Retinol) kanye nobungozi be-cutaneous squamous cell carcinoma (SCC) , uhlobo lwesibili oluvame kakhulu lwesikhumba umdlavuza phakathi kwabantu abanesikhumba esimhlophe. Ukuhlaziywa kwagqamisa ingozi encishisiwe yomdlavuza wesikhumba ngokwanda kwe-Vitamin A (Retinol) (iningi elitholakala emithonjeni yokudla hhayi izithasiselo).
Uvithamini A (Retinol) - I-Retinoid Yemvelo
I-Vitamin A, i-retinoid yemvelo encibilika ngamafutha, iyisakhi esibalulekile esisekela umbono ojwayelekile, isikhumba esinempilo, ukukhula nokukhula kwamangqamuzana, ukwenza ngcono ukusebenza kwamasosha omzimba, ukuzala nokukhula kwengane. Ukuba isakhi esibalulekile, Vitamin A ayikhiqizwa umzimba womuntu futhi itholakala ekudleni kwethu okunempilo. Ngokuvamile kutholakala emithonjeni yezilwane ezifana nobisi, amaqanda, ushizi, ibhotela, isibindi namafutha e-fish-isibindi ngendlela ye-retinol, uhlobo olusebenzayo lwe-Vitamin A, nasemithonjeni yezitshalo ezifana nesanqante, i-broccoli, ubhatata, obomvu. upelepele, isipinashi, upopo, umango kanye nethanga ngendlela yama-carotenoids, aguqulwa abe yi-retinol ngumzimba womuntu ngesikhathi sokugaya. Le bhulogi ichaza kabanzi ucwaningo oluhlaziye ukuhlobana phakathi kokuthatha i-Vitamin A yemvelo ye-retinoid kanye nengozi yomdlavuza wesikhumba.
Uvithamini A Nomdlavuza Wesikhumba
Yize ukudla kukaVitamin A kusiza impilo yethu ngezindlela eziningi, izifundo ezahlukahlukene phambilini zakhombisa ukuthi ukudla kakhulu i-retinol ne-carotenoids kungakhuphula ubungozi bemidlavuza njengomdlavuza wamaphaphu kubantu ababhemayo nakumdlavuza wendlala yabesilisa. Kodwa-ke, ngenxa yedatha elinganiselwe nengahambelani, ukuhlangana kokudla kweVitamin A kanye nengozi yomdlavuza wesikhumba akuzange kusungulwe ngokucacile.
Ukudla Okufanele Ukudla Ngemuva Kokuxilongwa Komdlavuza!
Akukho mdlavuza owodwa ofanayo. Dlulela ngale kwemihlahlandlela ejwayelekile yokudla kuwo wonke umuntu futhi wenze izinqumo ezenziwe ngezifiso ngokudla nezithasiselo ngokuzethemba.
Ukuhlangana phakathi kuka-Vitamin A (Retinol) kanye Nengozi Ye-Cutaneous Squamous Cell Carcinoma- Uhlobo Lomdlavuza Wesikhumba
Abacwaningi abavela eWarren Alpert Medical School yaseBrown University e-Providence, Rhode Island; Isikole Sezokwelapha saseHarvard eBoston, Massachusetts; kanye neNyuvesi yase-Inje eSeoul, eNingizimu Korea; ihlole idatha ehlobene nokuthathwa kwe-Vitamin A kanye nengozi ye-cutaneous squamous cell carcinoma (SCC), uhlobo lwesikhumba umdlavuza, kusukela kubahlanganyeli ezifundweni ezimbili ezinkulu, zesikhathi eside eziqanjwe ngokuthi I-Nurses' Health Study (NHS) kanye ne-Health Professionals Follow-Up Study (HPFS)(Kim J et al, JAMA Dermatol., 2019). I-Cutaneous squamous cell carcinoma (SCC) wuhlobo lwesibili oluvame kakhulu lomdlavuza wesikhumba ngezinga elilinganiselwe lesigameko elibikwe njengo-7% kuya ku-11% e-US. Lolu cwaningo lufake idatha evela kwabesifazane abangu-75,170 base-US ababambe iqhaza ocwaningweni lwe-NHS, abaneminyaka yobudala engama-50.4, namadoda angama-48,400 ase-US abambe iqhaza ocwaningweni lwe-HPFS, aneminyaka yobudala eyi-54.3. Idatha ibonise inani labantu abangu-3978 abanomdlavuza wesikhumba we-squamous cell phakathi neminyaka engu-26 neminyaka engu-28 yezikhathi zokulandelela ezifundweni ze-NHS ne-HPFS ngokulandelana.UKim J et al, JAMA Dermatol., 2019).
Imiphumela esemqoka yocwaningo ibhalwe ngezansi:
a. Kukhona ukuhlangana okuphambene phakathi kokudla kwe-vitamin A ye-retinoid yemvelo kanye nobungozi bokuthi i-squamous cell carcinoma (uhlobo lomdlavuza wesikhumba).
b. Abahlanganyeli baqoqwe ngaphansi kwesigaba sokusetshenziswa okuphezulu kakhulu kwansuku zonke kukavithamini A babe nengozi encishisiwe engu-17% ye-squamous cell carcinoma eqhathaniswa neqembu elidle ivithamini A.
c. Uvithamini A utholakale kakhulu emithonjeni yokudla hhayi kwizithasiselo zokudla kulezi zimo ngengcuphe encishisiwe ye-squamous cell carcinoma / cancer.
d. Ukudla okuphezulu kwe-vitamin A ephelele, i-retinol, ne-carotenoids efana ne-beta cryptoxanthin, i-lycopene, i-lutein ne-zeaxanthin, okuvame ukutholakala kwizithelo nemifino ehlukahlukene njenge-papaya, umango, amapentshisi, amawolintshi, ama-tangerines, i-pepper pepper, ummbila, ikhabe, utamatisi nemifino enamaqabunga aluhlaza, yayihlotshaniswa nengozi ephansi ye-squamous cell carcinoma / umdlavuza.
e. Le miphumela ibigqame kakhulu kubantu abanezimvukuzane nalabo ababenokuphendula kokushiswa yilanga njengezingane noma intsha.
Isiphetho
Ngamafuphi, lolu cwaningo olungenhla luphakamisa ukuthi ukusetshenziswa okwandisiwe kwe-retinoid yemvelo i-Vitamin A / Retinol (etholakala ikakhulu emithonjeni yokudla hhayi kwizithasiselo) kunganciphisa ubungozi bohlobo lomdlavuza wesikhumba obizwa nge-cutaneous squamous cell carcinoma. Kukhona ezinye izifundo eziqokomisa ukuthi ukusetshenziswa kwama-retinoid okwenziwa kukhombisile umthelela omubi emdlavuzeni wesikhumba onobungozi obukhulu. (URenu George et al, Australas J Dermatol., 2002) Ngakho Ukuba nokudla okulinganiselayo, okunempilo okunenani elifanele le-retinol noma i-carotenoids kuthathwa njengokuzuzisa. Yize le miphumela ibukeka ithembisa i-SCC yesikhumba, ucwaningo aluzange luhlole umphumela wokudla kukavithamini A kwezinye izinhlobo zesikhumba. zomdlavuza, okungukuthi, i-basal cell carcinoma ne-melanoma. Ucwaningo olwengeziwe luyadingeka ukuze kuhlolwe ukuthi ingabe i-vitamin (Retinol) A supplementation inendima ekuhlolweni kwe-chemoprevention ye-SCC.
Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.
Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.
Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.
Ukudla Okungokwakho Komdlavuza!
Umdlavuza uyashintsha ngokuhamba kwesikhathi. Enza ngendlela oyifisayo futhi uguqule umsoco wakho ngokusekelwe kunkomba yomdlavuza, ukwelashwa, indlela yokuphila, okuncamelayo kokudla, izinto ezingakuphathi kahle nezinye izici.
Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.