Iimbalasane
I-Curcumin evela kwi-spice Turmeric iphucule impendulo ye-FOLPOX chemotherapy kwizigulana ezinomhlaza we-colorectal njengoko kugxininiswe kwisigaba sesi-II solingo lwezonyango. Ukusinda ngokubanzi kwizigulane ezithatha i-FOLFOX ngokudibanisa ne-Curcumin supplements kwakuphindwe kabini xa kuthelekiswa neqela elithatha kuphela i-FOLFOX: unyango lwendalo olunokubakho kumhlaza we-colorectal. Kubandakanywa Curcumin njengenxalenye ye-colorectal Ukutya kwabaguli abanomhlaza ngelixa unyango lwe-FOLFOX lunokuba luncedo.
Izibonelelo zendalo zoMhlaza oColorectal
Njengokuba sikhula, iimpembelelo ezongezelekayo zazo zonke iinketho zobomi bethu kubandakanya ukutya, imithambo, indlela yokuphila, indlela esijamelana ngayo noxinzelelo, iindlela zokulala, kunye nezinye ezininzi, zinxibelelana nobume bethu bemvelo kunye nokuphosa uninzi lwemiceli mngeni enxulumene nempilo esiyifunayo ukujongana. Enye yeemeko ezinokuthi zivele ngaphezulu kubantu abadala abadala ngaphezulu kweminyaka engama-50 ubudala ngumhlaza obala, ochaphazela ikholoni / amathumbu amakhulu. Isibetho sokuchongwa komhlaza sisiganeko esiphazamisa ubomi kwaye umntu uzama ukwenza konke okusemandleni kwindawo yabo ukuphucula amathuba abo okusinda. Enye yezinto ezenziwa zizigulana lutshintsho ekudleni kwabo kukutya ukutya okunempilo, okunezinto eziphilayo kunye nezityalo (njengeyeza lendalo lomhlaza kubandakanya umhlaza wecolorectal); kwaye ukuthatha izongezo zendalo kufunyaniswe ukuba baneepropathi ezichasene nomhlaza ngokusetsha kwabo okanye ukuhanjiswa kusapho, izihlobo okanye ezinye izigulana. Nangona kunjalo, olu setyenziso lusebenzayo lwezongezo zendalo ngaphandle kokwazi ukuba lunxibelelana njani nonyango lwabo oluqhubekayo lomhlaza kuhlobo oluthile lomhlaza lunokunceda okanye lonzakalise unobangela wabo, yiyo loo nto kufuneka lwenziwe ngononophelo kwaye ngokubonisana neengcali zononophelo lwempilo.
Iimpawu zakwangoko zomhlaza womlomo wesibeleko ziquka iimpawu eziqhelekile ngamanye amaxesha zezitenxo zamathumbu ezinokuthi zingahoywa. Ubukho beepolyps kwikholoni okanye igazi kwisitulo nazo ziyimpawu zoku umhlaza. Uninzi lweepolyps kwikholoni xa zifunyenwe zingenawo umhlaza, kodwa ezinye zinokujika zibe zibi. Ukuba ifunyenwe kwaye inyangwe kwangoko ngelixa i-tumor ibekwe kwindawo, ine-prognosis enhle kakhulu kunye ne-5-year-survival rate ye-90% kodwa ukuba ifunyenwe xa i-tumor isasazeke kwii-lymph nodes kunye namanye amalungu (metastatic), izinga lokusinda linokuthi kakhulu. yahluka phakathi kwe-14-71% (Iinyani zeCancer Cancer Stat: Umhlaza weColorectal, NCI, 2019).
Ukutya okuTyiwa emva kokuChongwa koMhlaza!
Akukho mhlaza mibini ifanayo. Yiya ngaphaya kwezikhokelo zesondlo esiqhelekileyo kuwo wonke umntu kwaye wenze izigqibo ezizezakho malunga nokutya kunye nezongezo ngokuzithemba.
Ngaba iCurcumin ingayiphucula impendulo ye-FOLFOX Chemotherapy kwiColorectal Cancer?
I-Curcumin, imveliso yendalo ekhishwe kwi-spice Turmeric esetyenziswa rhoqo iphandwe kakhulu kuyo iipropathi anticancer. Uphononongo lwakutsha nje lweklinikhi yesigaba IIa esivulekileyo esinelebheli esilawulwa ngokungahleliwe esenziwe kwizigulana ezinomhlaza we-metastatic colorectal cancer (NCT01490996) xa kuthelekiswa ukusinda okupheleleyo kwezigulana ezifumana indibaniselwano ye-chemotherapy ebizwa ngokuba yi-FOLFOX (folinic acid / 5-FU / OXA) kunye neqela elifumana I-FOLFOX kunye ne-2 gram yomlomo we-curcumin supplements / day (CUFOX). Ukongezwa kweCurcumin ukuya kwi-FOLFOX kwafunyanwa kukhuselekile kwaye kuyanyamezeleka kwizigulana ezinomhlaza kwaye azizenzakalisi iziphumo ebezingalindelekanga zekhemotherapy. Ngokwamazinga okuphendula, iqela le-CUFOX lalinesiphumo esingcono kakhulu sokusinda kunye nokuqhubeka nokusinda simahla kwiintsuku ezingama-120 ngaphezulu kweqela le-FOLFOX kunye nokusinda ngokubanzi kukuphindaphindwe kabini kwi-CUFOX ngeentsuku ezingama-502 (ngaphezulu konyaka onesiqingatha) kuthelekiswa nama-200 kuphela iintsuku (ngaphantsi konyaka) kwiqela le-FOLFOX (I-Howell LM okqhubekayo, J Nutriti, 2019).
isiphelo
Isishwankathelo, izongezelelo ze-Curcumin okanye ukutya / ukutya okunesondlo kwi-Curcumin kunokuphucula impendulo ye-FOLFOX chemotherapy kwizigulane zomhlaza. Izifundo ezinjalo ngaphandle kobukhulu besampulu ezincinci, ziluncedo kakhulu kwaye ziyakhuthaza ekuxhaseni ukusetyenziswa kweemveliso ezithile zendalo ngonyango oluthile lwechemotherapy. Amachiza e-FOFOX e-chemotherapy asebenza ngokubangela umonakalo we-DNA kwindawo umhlaza iiseli kunye nokufa kweeseli. Iiseli zomhlaza zisebenzisa iindlela zokubaleka ezahlukeneyo ukuze ziphephe i-chemo ekuyibangele ukuba itshabalale. I-Curcumin kunye nezenzo zayo ezininzi kunye neethagethi zinokunceda ukunciphisa iindlela zokumelana ne-FOLFOX, ngaloo ndlela iphucula izinga lokuphendula kunye neengxaki zokusinda kwisigulane somhlaza, ngaphandle kokongeza kumthwalo wetyhefu. Nangona kunjalo, ukuthatha i-Curcumin okanye nayiphi na enye imveliso yendalo kunye ne-chemo kufuneka yenziwe kuphela ngokusekelwe kwinkxaso yesayensi kunye nobungqina ngokubonisana nodokotela.
Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.
Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.
Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.
ISondlo esiSiqu soMhlaza!
Umhlaza uyatshintsha ngokuhamba kwexesha. Yenza ngokwezifiso kwaye uguqule isondlo sakho ngokusekwe kwisalathiso somhlaza, unyango, indlela yokuphila, ukhetho lokutya, i-allergies kunye nezinye izinto.
Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) sesona sixhobo sendalo somhlaza kunye neziphumo ebezingalindelekanga zonyango.