Iimbalasane
Ileyibhile evulekileyo, iziko elinye, isifundo sesigaba soku-I esenziwe ngabaphandi abavela eJapan bacebise ukuba idosi yemihla ngemihla ye-12 g ye-GBS-01, equlathe malunga ne-4g yesiqhamo se-burdock esityebileyo kwi-arctigenin, inokukhuseleka ngokwezonyango kwaye inokuba neenzuzo ezinokwenzeka izigulane ezine-pancreatic pancreatic umhlaza refractory kunyango lweGemcitabine. Nangona kunjalo, amalingo amakhulu achazwe kakuhle ayafuneka ukuseka ezi ziphumo.
IBurdock kunye neeComputer zayo ezisebenzayo
I-Arctium lappa, eyaziwa ngokuba yi-burdock, isityalo esingapheliyo esivela e-Asia naseYurophu. IBurdock ngoku ithandwa kwihlabathi liphela kwaye iyalinywa kwaye isetyenziswa njengemifuno kwiindawo ezininzi zehlabathi. Iingcambu, amagqabi, kunye nembewu yesi sityalo zisetyenziswa kunyango lwesiTshayina njengeyeza lokunyanga izifo ezahlukeneyo. Iingcambu zeBurdock zigcwele ii-antioxidants kwaye zikwajongwa njengezineziphumo zokulwa nomhlaza.
Izifundo ezahlukeneyo zangaphambi kokuba zivelise ukuba i-burdock inokuba ne-anti-inflammatory, antibacterial, antidiabetic, antiulcerogenic, hepatoprotective, kunye ne-anticancer. Iimpawu eziphambili zezicatshulwa ze-burdock ziquka i-caffeoylquinic acid derivatives, i-lignans kunye ne-flavonoids ezahlukeneyo.
Amagqabi e-burdock ikakhulu aneentlobo ezimbini ze-lignans:
- IArctiin
- IArctigenin
Ngaphandle kwezi, i-phenolic acid, i-quercetin, i-quercitrin kunye ne-luteolin zinokufumaneka kumagqabi e-burdock.
Imbewu yeBurdock iqulethe ii-phenolic acid ezinje ngeCaffeic acid, iChlorogenic acid kunye neCynarin.
Ezona zinto ziphambili ezisebenzayo kwiingcambu zeBurdock ziArctiin, Luteolin kunye neQuercetin rhamnoside enokuthi ibe nefuthe kwiziphumo ezichasene nomhlaza.
Ukusetyenziswa okuThunyelweyo kweBurdock Extracts
IBurdock isetyenziswe ngokubanzi kwiMveli yeMveli yaseTshayina kwezi njongo zilandelayo, nangona kungekho bungqina beklinikhi bokuxhasa ukusetyenziswa kwayo kwezi meko zininzi:
- Ukucoca igazi
- Ukunciphisa uxinzelelo lwegazi
- Ukunciphisa igawuthi
- Ukunciphisa i-hepatitis
- Ukunciphisa izifo ezosulelayo
- Ukunciphisa iswekile yegazi kwizigulana ezineswekile
- Ukunyanga ukuphazamiseka kolusu njenge-eczema kunye ne-psoriasis
- Ukunciphisa imibimbi
- Ukunyanga ukuphazamiseka kokudumba
- Ukunyanga uGawulayo
- Ukunyanga uMhlaza
- Njenge-diuretic
- Njengeti ye-antipyretic yokunyanga umkhuhlane
Ukutya okuTyiwa emva kokuChongwa koMhlaza!
Akukho mhlaza mibini ifanayo. Yiya ngaphaya kwezikhokelo zesondlo esiqhelekileyo kuwo wonke umntu kwaye wenze izigqibo ezizezakho malunga nokutya kunye nezongezo ngokuzithemba.
Ngaba iBurdock Extracts izakuxhamla kwizigulana ezinomhlaza wePancreatic ezinokuphikisa kwiGemcitabine?
Ngokutsho kwe-American Cancer Society, umhlaza we-pancreatic ngowona wesithoba uxhaphakileyo umhlaza kwabasetyhini kunye nomhlaza weshumi uxhaphake kakhulu emadodeni kwaye wenze i-7% yabo bonke ababulawa ngumhlaza.
Ikwangunobangela wesine ophambili wokusweleka komhlaza emadodeni nakwabasetyhini.
I-Gemcitabine yinkqubo esemgangathweni yokuqala ye-chemotherapeutic arhente yomhlaza wepancreatic. Nangona kunjalo, umhlaza wepancreatic umhlaza womoya waziwa kakuhle ukuba ubonakaliswa yihypoxia ebukhali, imeko apho umzimba uvinjelwa ukubonelelwa ngokwaneleyo kweoksijini kwinqanaba lezicubu, kunye nokususwa kwezondlo, ngakumbi iswekile. I-Hypoxia inyusa ukunganyangeki ngokuchasene ne-gemcitabine, ngaloo ndlela kuthintelwe izibonelelo zale chemotherapy.
Yiyo loo nto, abaphandi abavela kwiSibhedlele seSizwe seCancer Centre East, Meiji Pharmaceutical University, National Cancer Centre, Kracie Pharma, Ltd. eToyama, kunye neTokyo University of Science, eJapan bavavanye iikhompawundi ezahlukileyo ezinokuphelisa ukunyamezelana kweeseli zomhlaza kubundlala glucose kwaye i-hypoxia, kunye ne-arctigenin echongiweyo, eyona nto iphambili ifunyenwe kwizicatshulwa zeBurdock, njengeyona ndawo ilungileyo yokuvavanywa kuvavanyo lweklinikhi, ngenxa yomsebenzi wayo wokuchasana oqwalaselweyo kwiimodeli ezininzi zomhlaza kunye neeprofayili ezaneleyo zokhuselo xa zinikwa idosi ukuya kuthi ga kwikhulu lemihla ngemihla idosi efunekayo kwimisebenzi ye-antitumor kwiimpuku. (UMasafumi Ikeda okqhubekayo, iCancer Sci., 2016)
Abaphandi basebenzise ichiza lomlomo i-GBS-01, isicatshulwa kwisiqhamo seBurdock, esisityebi kwi-arctigenin, kwizigulana ezili-15 ezine-pancreatic pancreatic. umhlaza refractory ukuba gemcitabine. Kulingo, baphanda ngedosi ephezulu enyanyezelweyo ye-GBS-01 kwaye bajonga ubutyhefu bokunciphisa iDose. I-Dose-limiting toxicities (DLTs) ibhekiselele kwinkangeleko yebakala lesi-4 lwe-hematological/blood toxicity kunye nebakala lesi-3 okanye lesi-4 letyhefu engeyiyo eyehematological/yegazi ngeentsuku ezingama-28 zokuqala zonyango.
Kolu phando, bafumanise ukuba akukho zimpawu zetyhefu yegazi yebanga lesi-4 kunye nebakala lesi-3 okanye lesi-4 ezingezizo ezetyhefu kuzo naziphi na izigulana ezibhalisileyo, nakweyiphi na idosi ezintathu ezisetyenzisiweyo (mihla le i-3.0 g, 7.5 g okanye i-12.0 g) . Nangona kunjalo, iityhefu ezinqabileyo ziye zajongwa njengokunyuka kwe-serum γ ‐ glutamyl transpeptidase, ukonyuka kweglucose yegazi, kunye nokwanda kwe-bilirubin iyonke yeserum.
Uphononongo luchaze idosi ekhuthazwayo ye-GBS-01, isicatshulwa esityebileyo kwi-arctigenin evela eBurdock, ukuba ibe yi-12.0 g yonke imihla, kuba akukho zi-DLTs zabonwa kuwo nawaphi na amanqanaba edosi amathathu. Idosi yemihla ngemihla ye-12.0 g GBS-01 yayimalunga ne-4.0 g ye-burdock yeziqhamo.
Ngaphandle kwabaguli abatya isicatshulwa seBurdock, izigulana ezi-4 zinezifo ezizinzileyo kwaye i-1 ibonise ukuphendula okwethutyana ngexesha lokujonga. Ukuchaneka, inqanaba lokuphendula lalingama-6.7% kwaye inqanaba lokulawulwa kwezifo lalingama-33.3%. Uphononongo lufumanise ukuba ukuqhubela phambili kokuma kunye nokusinda kwabaguli zizinyanga eziyi-1.1 kunye neenyanga ezi-5.7 ngokwahlukeneyo.
isiphelo
I-Burdock extracts kunye neengcambu zibhekwa njenge-anti-inflammatory, antibacterial, antidiabetic, antiulcerogenic, hepatoprotective, kunye ne-anti-cancer properties. Uphononongo lwekliniki luka-2016 lwesigaba I senziwe ngabaphandi abavela eJapan bacebise ukuba idosi yemihla ngemihla ye-GBS-12 (equlathe malunga ne-01 g yesiqhamo se-burdock esityebileyo kwi-arctigenin) inokukhuseleka ngokwaseklinikhi kwaye inokuba neenzuzo ezinokwenzeka kwizigulana ezine-pancreatic pancreatic. i cancer refractory kunyango lweGemcitabine. Nangona kunjalo, ulingo olukhulu oluchazwe kakuhle luyimfuneko ukuseka ezi ziphumo, ngaphambi kokucebisa ukusetyenziswa kwe-arctigenin kwizigulana ezinomhlaza wepancreatic.
Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.
Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.
Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.
ISondlo esiSiqu soMhlaza!
Umhlaza uyatshintsha ngokuhamba kwexesha. Yenza ngokwezifiso kwaye uguqule isondlo sakho ngokusekwe kwisalathiso somhlaza, unyango, indlela yokuphila, ukhetho lokutya, i-allergies kunye nezinye izinto.
Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) sesona sixhobo sendalo somhlaza kunye neziphumo ebezingalindelekanga zonyango.