Iimbalasane
Izifundo ezincinci zeklinikhi ziye zafumanisa ukuba i-Coenzyme Q10 / CoQ10 / ubiquinol supplementation inokuba neenzuzo ezinokubakho kwiindidi ezahlukeneyo zomhlaza ezinje ngomhlaza wamabele, i-leukemia, i-lymphoma, i-melanoma kunye nomhlaza wesibindi ngokunciphisa amanqanaba ee-cytokine markers egazini, ukuphucula umgangatho ubomi, ukunciphisa iziphumo ebezingalindelekanga zonyango ezinje nge-cardiotoxicity, ukunciphisa ukubuyela kwakhona okanye ukuphucula ukusinda. Yiyo loo nto ukuthatha i-Coenzyme Q10 / CoQ10 yokutya okutyebileyo kunokuba luncedo kwezi zigulana zinomhlaza. Iziphumo zifuna ukungqinisiswa kwizifundo ezikhulu.
Yintoni iCoenzyme Q10 / Co-Q10?
ICoenzyme Q10 (Co-Q10) yimichiza eyenziwe ngokwendalo ngumzimba wethu kwaye iyafuneka ekukhuleni nasekugcinweni. Inezinto ezinamandla zokulwa ne-antioxidant kwaye ikwanceda ukubonelela ngamandla kwiiseli. Ifom esebenzayo yeCo-Q10 ibizwa ngokuba yi-ubiquinol. Ngobudala, imveliso ye-Co-Q10 emzimbeni wethu iyancipha. Umngcipheko wezifo ezininzi, ngakumbi ngexesha lokuguga sele ufunyenwe unxulunyaniswa nokwehla kwamanqanaba eCoenzyme Q10 (Co-Q10).
ICoenzyme Q10 / Coq10 Imithombo yokutya
ICoenzyme Q10 okanye iCoQ10 inokufumaneka kukutya okufana:
- Iintlanzi ezinamanqatha ezinje nge salmon kunye ne mackerel
- Iinyama ezinje ngenyama yenkomo kunye nehagu
- Imifuno enje nge-broccoli kunye nekholifulawa
- Amantongomane afana namandongomane kunye neepistachios
- Imbewu yeSesame
- Inyama yomzimba efana nesibindi senkukhu, intliziyo yenkukhu, isibindi senyama yenkomo njl.
- Iziqhamo ezinje ngamaqunube
- Iimbotyi zesoya
Ngaphandle kwemithombo yokutya kwendalo, iCoenzyme-Q10 / CoQ10 ikwafumaneka njengezongezo zokutya ngohlobo lwee-capsules, iipilisi ezihlafunwayo, iisiraphu zamanzi, iifers kunye nenjeksi efakwa ngaphakathi.
Izibonelelo eziBanzi zezeMpilo zeCoenzyme Q10 / Co-Q10 / Ubiquinol
ICoenzyme Q10 (CoQ10) yaziwa ngokuba nezibonelelo ezininzi zezempilo Ukulandela ezinye zezibonelelo zezempilo ngokubanzi zeCoenzyme Q10 (Co-Q10):
- Ngamana unokunceda ukunciphisa umngcipheko wezifo zentliziyo
- Ngamana unokunceda ukunciphisa i-migraine
- Ngaba ingayilungela ingqondo kwaye incede ukunciphisa iimpawu ze-Alzheimer's kunye nezifo zika-Parkinson
- Ngamana unokunceda ukunyanga ukungachumi
- Ngamana unokunceda ukunciphisa i-cholesterol
- Ngamana unokunceda ukuphucula ukusebenza komzimba kwabanye abantu abane-muscular dystrophy (iqela lezifo ezibangela ubuthathaka obuqhubekayo kunye nokulahleka kwemisipha).
- Ngamana unokunceda ukuthintela isifo seswekile
- Ngamana unokuvuselela amajoni omzimba
- Ngamana ingakhusela intliziyo kumonakalo obangelwe ngamachiza athile e-chemotherapy
Olunye uphononongo lukwabonisa ukuba amanqanaba aphezulu eCoenzyme Q10 anokubonelela ngezibonelelo ezinxulumene nomngcipheko oncitshisiweyo wezifo ezithile kubandakanya ezinye umhlaza iintlobo.
Ukutya okuTyiwa emva kokuChongwa koMhlaza!
Akukho mhlaza mibini ifanayo. Yiya ngaphaya kwezikhokelo zesondlo esiqhelekileyo kuwo wonke umntu kwaye wenze izigqibo ezizezakho malunga nokutya kunye nezongezo ngokuzithemba.
Iziphumo ebezingalindelekanga zeCoenzyme Q10 / Ubiquinol
Ukuthatha ukutya kweCoenzyme Q10 / CoQ10 kukhuselekile ngokubanzi kwaye kuyanyamezeleka. Nangona kunjalo, ukusetyenziswa gwenxa kweCoenzyme Q10 kunokubangela iziphumo ebezingalindelekanga kubandakanya:
- I sizathu
- Utywala
- Uhudo
- Ukuguquka
- Intlungu yesisu
- Ukulala
- Ukuphelelwa kwesidlo
Abanye abantu baphinde baxela ezinye iziphumo ebezingalindelekanga zeCoenzyme Q10 ezinje ngokuthamba kolusu.
ICoenzyme Q10 / Ubiquinol kunye neCancer
I-Coenzyme Q10 ifumene umdla kuluntu lwezenzululwazi njengabantu abadala kunye nabantu abaneemeko zonyango ngokubanzi babenamanqanaba aphantsi e-CoQ10. Ukusukela oko umhlaza yayixhaphakile phakathi kwabantu abadala kwaye umngcipheko womhlaza wonyuka ngokuya ngeminyaka, kukhokelele kwizifundo ezahlukeneyo zokuvavanya ukuba yeyiphi imiphumo le enzyme enokuba nayo emzimbeni. Apha ngezantsi kukho imizekelo yezinye izifundo ezenziwayo ukuvavanya umanyano phakathi kweCoenzyme Q10 kunye nomhlaza. Masijonge ngokukhawuleza kwezi zifundo kwaye sifumanise ukuba ukutya okutyebileyo kweCoenzyme Q10/CoQ10 kunokubanceda abaguli abanomhlaza okanye hayi.
Ukusetyenziswa kwe-Co-Q10 / i-Ubiquinol kwizigulana ezinomhlaza wamabele
Ukusetyenziswa kwe-Co-Q10 / i-Ubiquinol kunokuba nezibonelelo zokunciphisa amaNqaku aVuthayo kwizigulana ezinomhlaza webele.
Kwi-2019, uphononongo lwenziwe ngabaphandi abavela kwiYunivesithi yase-Ahvaz Jundishapur yezeNzululwazi e-Iran ukuvavanya iziphumo ezinokubakho / izibonelelo ezinokubakho kwi-Co-enzyme Q10 (CoQ10) / ubiquinol yokuxhasa enokuba nayo kwizigulana ezinomhlaza wamabele. Ukudumba okungapheliyo kuyaziwa ngokwandisa ukukhula kwethumba. Yiyo loo nto, baqala ukuvavanya ifuthe / isibonelelo seCoQ10 / ubiquinol yokuxhasa kumanqaku athile okudumba anje ngee-cytokines Interleukin-6 (IL6), Interleukin-8 (IL8) kunye ne-vascular endothelial growth factor (VEGF) egazini lezigulana ezingama-30 zomhlaza wamabele. ukufumana unyango lwe-tamoxifen kunye nezifundo ze-29 eziphilileyo. Iqela ngalinye lahlulwa lababini ngeseti enye yezigulana ezinomhlaza wamabele kunye nezifundo ezisempilweni ezifumana i-placebo kwaye elinye iseti lifumana i-100 mg CoQ10 kanye ngemini kangangeenyanga ezimbini.
Uphononongo lufumanise ukuba ukuxhaswa kweCoQ10 kunciphise amanqanaba e-IL-8 kunye ne-IL-6 serum kodwa hayi amanqanaba e-VEGF xa kuthelekiswa ne-placebo. (Zahrooni N et al, Ther Clin Risk Manag., 2019) Ngokusekwe kwiziphumo zeli qela lincinci kakhulu lezigulana, ukuxhaswa kweCoQ10 kunokuba nokusebenza ekunciphiseni amanqanaba e-cytokine, kwaye ke kunciphise iziphumo zokudumba ezibangelwa zizigulana ezinomhlaza wamabele. .
Ukusetyenziswa kwe-Co-Q10 / i-Ubiquinol kunokuba nezibonelelo zoPhuculo loMgangatho woBomi beZigulana ezinomhlaza wamabele
Kweli qela linye labaguli abanomhlaza wamabele abangama-30 abaneminyaka eyi-19-49 ababekwiyeza leTamoxifen, bahlula phakathi kwamaqela ama-2, elinye lathatha i-100 mg / usuku lwe-CoQ10 iinyanga ezimbini kunye nelinye iqela kwi-placebo, abaphandi bavavanya ifuthe kumgangatho ubomi (iQoL) yezigulana ezinomhlaza wamabele. Emva kokuhlalutya idatha, abaphandi bagqiba kwelokuba i-CoQ10 yokuncedisa inefuthe elibonakalayo kwimeko yomzimba, yentlalontle kunye nengqondo yabasetyhini abanomhlaza wamabele. (IHosseini SA okqhubekayo, iPsychol Res Behav Manag., 2020 ).
Ukusetyenziswa kwe-Co-Q10 / i-Ubiquinol kunokuba nezibonelelo zokuphucula ukusinda kwizigulana ezinomhlaza kwinqanaba lokugqibela.
Uphononongo olwenziwe ngu-N Hertz kunye no-RE Lister wase-Denmark baphonononge ukusinda kwezigulana ezingama-41 ezinomhlaza wokugqibela ofumene izongezo ze-coenzyme Q (10) kunye nomxube wezinye i-antioxidants ezinjenge vithamin C, selenium, folic acid kunye ne beta-carotene . Owona mhlaza uphambili wezi zigulana ubekwe ebeleni, ebuchotsheni, emiphungeni, kwizintso, amanyange, umqala, isisu, ikholon, iprostate, amaqanda kunye nolusu. Uphononongo lufumanise ukuba ukusinda okwenyani okungaphezulu kunokuba ngaphezulu kwe-40% ngaphezulu kunokubikezela okusindileyo. (N Hertz kunye no-RE Lister, J Int Med Res, Nov-Dec)
Abaphandi bagqiba kwelokuba ukulawulwa kweCoenzyme Q10 kunye nezinye i-antioxidants kunokuba nezibonelelo ezinokubakho zokuphucula ukusinda kwabaguli abanomhlaza kwinqanaba lokugqibela kwaye bacebise izilingo ezinkulu zeklinikhi zokuqinisekisa ezi zibonelelo.
ICoenzyme Q10 / Ubiquinol inokuba nezibonelelo zokunciphisa iAntracyclines-eyenzelwe iCardiotoxicity Iziphumo ebezingalindelekanga kubantwana abaneLeukemia neLymphoma
Uphononongo olwenziwe ngabaphandi kwiZiko loNyango lwezoNyango lweCardiology, iYunivesithi yesi-2 yaseNaples e-Italiya kuvavanye ifuthe lonyango lweCoenzyme Q10 kwi-cardiotoxicity kubantwana abangama-20 abane-Acute Lymphoblastic Leukemia okanye i-Non-Hodgkin Lymphoma ephathwe nge-Anthracyclines. Uphononongo lufumene umphumo okhuselayo weCoenzyme Q10 ekusebenzeni kwentliziyo ngexesha lonyango kunye ne-ANT kwezi zigulana. (D Iarussi okqhubekayo, Mol Izinto kwiMed., 1994)
Sebenzisa i-Recombinant interferon alpha-2b kunye ne-coenzyme Q10 njengonyango olusebenzayo lwonyango lwe-melanoma lunokunciphisa ukubuyela kwakhona
Uphononongo olwenziwa ngabaphandi abavela kwiYunivesithi yamaKatolika ye-Sacred Heart, eRoma, eItali bavavanya umphumo wonyango lwe-3 iminyaka kunye ne-dose ephantsi ye-interferon alpha-2b kunye ne-coenzyme Q10 ngokuphindaphindiweyo emva kweminyaka eyi-5 kwizigulane ezinesigaba I kunye ne-II. melanoma (uhlobo lwesikhumba umhlaza) kunye nezilonda ezisuswe ngotyando. (Luigi Rusciani et al, Melanoma Res., 2007)
Uphononongo lufumanise ukuba ukusetyenziswa kwexesha elide kwethamo elincomekayo le-interferon alpha-2b kunye ne-coenzyme Q10 kunciphise kakhulu amaqondo okuphinda-phinda kwaye kwaba neziphumo ezibi.
Amanqanaba eSerum asezantsi eCoenzyme Q10 anokudityaniswa noPhawu oluPhezulu lokuDumba emva kokuhlinzwa kwiCancer Cancer
Kwisifundo esenziwe ngabaphandi besibhedlele iTaichung Veterans General Hospital kunye neYunivesithi yaseChung Shan Medical, eTaichung eTaiwan, bavavanya umbutho phakathi kwamanqanaba e-coenzyme Q10 kunye nokudumba kwizigulana ezine-hepatocellular carcinoma (umhlaza wesibindi) emva kotyando. Uphononongo lufumanise ukuba abaguli abanomhlaza wesibindi banamanqanaba asezantsi kakhulu e-coenzyme Q10 kunye namanqanaba aphezulu kakhulu wokudumba emva kotyando. Yiyo loo nto abaphandi bagqiba kwelokuba i-coenzyme Q10 inokuthi ithathelwe ingqalelo njengonyango lwe-antioxidant kwizigulana ezinomhlaza wesibindi ezinokuhlinzwa okungaphezulu. (UHsiao-Tien Liu okqhubekayo, Izondlo., 2017)
Amanqanaba asezantsi eCoenzyme Q10 anokunyusa umngcipheko weeCancer ezithile
Isifundo esenziwe ngabaphandi abasuka kwiYunivesithi yaseYuzuncu Yil, eVan eTurkey bafumanisa ukuba izigulana ezinomhlaza wemiphunga zinamanqanaba asezantsi eCoenzyme Q10. (Ufuk Cobanoglu et al, I-Asia Pac J yeCrev Prev., 2011)
Olunye uphononongo olwenziwe ngabaphandi abasuka kwiDyunivesithi yaseHawaii eManoa kuvavanye ukudibana kwamanqanaba e-plasma CoQ10 ngomngcipheko womhlaza wamabele, kuphando lokulawula imeko yabasetyhini baseTshayina kwi-Shanghai Women's Health Study (SWHS), kwaye bafumanisa ukuba abo Amanqanaba asezantsi e-CoQ10 ayanyaniswa nomngcipheko okhulayo womhlaza wamabele. (URobert V Cooney okqhubekayo, iCancer Epidemiol Biomarkers Prev., 2011)
isiphelo
Umgangatho wempembelelo yobomi ngummandla obalulekileyo wophando kuba uchaphazela phantse yonke imiba yobomi bezigulane. Abaninzi abasindileyo bomhlaza banomgangatho ophantsi wobomi kwaye bajongene nemiba yokukhathala, ukudandatheka, i-migraines, iimeko ezivuthayo njl. Ukuthatha ukutya okutyebileyo kwe-Coenzyme Q10 / CoQ10 / ubiquinol kunokuba luncedo ngokuvuselela i-metabolism ye-oxidative yesigulana ngaloo ndlela inika isigulane amandla angakumbi ngexesha. inqanaba leselula. Izilingo ezincinci zeklinikhi ezahlukeneyo zavavanya impembelelo yeCoenzyme Q10/CoQ10/ubiquinol supplementation kwizigulane ezineentlobo ezahlukeneyo i cancer. Baye bafumanisa ukuba i-CoQ10 / ubiquinol supplementation ineenzuzo ezinokubakho kwiintlobo ezahlukeneyo zomhlaza ezifana nomhlaza webele, i-leukemia, i-lymphoma, i-melanoma kunye nomhlaza wesibindi. I-CoQ10 ibonise imiphumo emihle (iinzuzo) ngokunciphisa amanqanaba eempawu ze-cytokine ezivuthayo egazini kunye nokuphucula umgangatho wobomi kwizigulane zomhlaza webele, ukunciphisa iziphumo ezichaphazelekayo zonyango ezifana ne-anthracycline-induced cardiotoxicity kubantwana abane-leukemia kunye ne-lymphoma, ukunciphisa ukuphindaphinda izigulane ze-melanoma okanye ukuphucula ukusinda kwizigulane ezinomhlaza wokugqibela. Nangona kunjalo, izilingo ezinkulu zeklinikhi ziyafuneka ukwenza isigqibo sokwenyani malunga nokusebenza / iinzuzo zeCoenzyme Q10/CoQ10/ubiquinol.
Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.
Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.
Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.
ISondlo esiSiqu soMhlaza!
Umhlaza uyatshintsha ngokuhamba kwexesha. Yenza ngokwezifiso kwaye uguqule isondlo sakho ngokusekwe kwisalathiso somhlaza, unyango, indlela yokuphila, ukhetho lokutya, i-allergies kunye nezinye izinto.
Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) sesona sixhobo sendalo somhlaza kunye neziphumo ebezingalindelekanga zonyango.