Mfundo
Kafukufuku wamankhwala wochitidwa ndi magulu osiyanasiyana ofufuza adasanthula zomwe zimachitika pakumwa zakumwa za glutamine, amino acid wosafunikira, pamlingo wambiri kupweteka kwapadera komwe kumayambitsa matendawa kapena kumeza zovuta komanso kuchepa thupi kwa Odwala khansa ya m'mapapo. Zotsatira za kafukufukuyu zikuwonetsa kuti kuwonjezereka kwapakamwa kwa glutamine kungathandize mapapu khansa odwala pochepetsa kuchuluka kwa kutupa kwa esophagus, kumeza zovuta / zovuta & kuonda komwe kumakhudzana.
Esophagitis mu Odwala Khansa Yam'mapapo
Khansara ya m'mapapo ndiyo yomwe imayambitsa kufa kwa khansa mwa amuna ndi akazi padziko lonse lapansi ndipo imawerengera opitilira 18% mwa onse omwe amafa ndi khansa (GLOBOCAN, 2018). Ndi chithandizo chaposachedwa chamankhwala, kuchuluka kwa mapapo atsopano khansa milandu yakhala ikuchepera zaka zingapo zapitazi (American Cancer Society, 2020). Kutengera mtundu ndi gawo la khansayo, momwe mapapu amagwirira ntchito komanso thanzi la wodwalayo, chithandizo cha wodwala khansa ya m'mapapo chimasankhidwa kuchokera kunjira zosiyanasiyana kuphatikiza radiotherapy, chemotherapy, immunotherapy, chithandizo chomwe chalunjika komanso opaleshoni. Komabe, ambiri mwa mankhwalawa amalumikizidwa ndi zotsatira zanthawi yayitali komanso zazifupi. Chimodzi mwazowopsa, zosasangalatsa komanso zowawa zomwe zimawonedwa mwa odwala khansa ya m'mapapo omwe adalandira chithandizo cha radiation pachifuwa ndi esophagitis.
Esophagitis ndikutupa kwa kholingo, chubu chopindika chomwe chimalumikiza pakhosi ndi m'mimba. Nthawi zambiri, kuyambika kwa ma radiation-induced esophagitis (ARIE) kumachitika mkati mwa miyezi itatu pambuyo pa radiotherapy ndipo nthawi zambiri kumabweretsa mavuto akumeza. Chifukwa chake, kafukufuku wambiri adachitika kuti apeze njira zopewera ndikuwongolera ma esophagitis omwe amachititsa odwala khansa. Kafukufuku wambiri wofalitsidwa posachedwa adanenanso zakugwiritsa ntchito zowonjezera zowonjezera monga glutamine popewa kapena kuchedwetsa radiation yotulutsa esophagitis. L-Glutamine, yemwe amadziwika kuti Glutamine ndi amino acid wosafunikira omwe amapangidwa ndi thupi ndipo amathanso kupezeka kuchokera kuzakudya zosiyanasiyana zomwe zimaphatikizapo nyama monga mkaka, zopangira mkaka, mazira ndi nyama, ndi magwero azomera monga monga kabichi, nyemba, sipinachi, parsley ndi masamba a beet. Komabe, glutamine, yomwe imapanga 3% ya ma aminoacid omwe amapezeka muminyewa yathu ya mafupa, nthawi zambiri imachepetsedwa ndi odwala khansa omwe amatsogolera kuonda ndi kutopa.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Kafukufuku wokhudzana ndi Oral Glutamine Supplements & Radiation-Induction Swallowing zovuta mu Cancer Lung
Kuphunzira ndi Chipatala cha Far Eastern Memorial, ku Taiwan
Kafukufuku wam'chipatala waposachedwa wochitidwa ndi ofufuza ku Far Eastern Memorial Hospital, ku Taiwan pakati pa Seputembara 2014 mpaka Seputembara 2015, zomwe zapezeka kuchokera kwa odwala 60 omwe ali ndi khansa ya m'mapapo osakhala yaying'ono kuphatikiza amuna 42 ndi akazi 18, azaka zapakati pa 60.3, adayesedwa . (Chang SC et al, Medicine (Baltimore), 2019) Odwalawa adalandira ma regimens opangidwa ndi platinamu ndi ma radiotherapy nthawi yomweyo, ndi othandizira kapena osapatsa mkamwa glutamine wowonjezera chaka chimodzi. Ofufuzawa adapeza kuti patadutsa miyezi 1, glutamine supplementation yachepetsa kuchuluka kwa magiredi 26.4/2 oyambitsa ma radiation-omwe amachititsa esophagitis / mavuto akumeza mpaka 3% poyerekeza ndi 6.7% mwa odwala omwe sanalandire zowonjezera za glutamine. Zinawonetsanso kuti kuchuluka kwa kuchepa thupi kunatsika mpaka 53.4% mwa odwala omwe amapatsidwa glutamine poyerekeza ndi 20% mwa odwala omwe sanalandire glutamine. Glutamine supplementation yachedwetsanso kuyambika kwa radiation-indophagitis kwamasiku 73.3 (Chang SC et al, Medicine (Baltimore), 5.8).
Phunziro la Necmettin Erbakan University Meram Medicine School, Turkey
Mu kafukufuku wina wachipatala wochitidwa ndi ofufuza ochokera ku Necmettin Erbakan University Meram Medicine School, Turkey, pakati pa 2010 ndi 2014, deta yochokera ku 122 Stage 3 mapapu omwe sanali ang'onoang'ono. khansa odwala adawunikidwa (Kanyilmaz Gul et al, Zakudya Zachipatala., 2017). Odwalawa adalandira chemotherapy yanthawi yomweyo (ndi Cisplatin / carboplatin + pactitaxel kapena Cisplatin + Etoposide, kapena Cisplatin + Vinorelbine) ndi radiotherapy, popanda kapena pakamwa supplementation. Odwala onse 56 (46%) adawonjezeredwa ndi glutamine ya m'kamwa. Ofufuzawa adapeza kuti patadutsa miyezi 13.14, glutamine supplementation yachepetsa kuchuluka kwa kalasi ya 2-3 yoopsa yochokera ku radiation / esophagitis / kumeza zovuta mpaka 30% poyerekeza ndi 70% mwa iwo omwe sanalandire zowonjezera za glutamine. Adawunikiranso kuti kuchuluka kwa kuchepa kwa thupi kudatsika mpaka 53% mwa odwala omwe amathandizidwa ndi glutamine poyerekeza ndi 86% mwa odwala omwe sanalandire glutamine. Kafukufukuyu adawonetsanso kuti kuphatikiza kwa glutamine sikunayambitse kuwonongeka kwa chotupa ndi zotsatira zopulumuka (Kanyilmaz Gul et al, Clin Nutr., 2017).
Kodi Oral Glutamine supplementation Angachepetse Esophagitis kapena Kumeza Mavuto Odwala Khansa Yam'mapapo?
Mwachidule, kafukufukuyu akuwonetsa kuti kudya kwapakamwa kwa glutamine kumatha kupindulitsa odwala omwe ali ndi khansa ya m'mapapo omwe si ang'onoang'ono pochepetsa zovuta za esophagitis / kumeza komanso kuchepa thupi, motero amawongolera moyo wawo. Komabe, popeza kafukufuku wam'mbuyomu wa in vitro adawonetsa kuti glutamine ikhoza kuthandizira kukula kwa maselo a khansa, akatswiri a oncologists nthawi zambiri sankafuna kupereka glutamine mu khansa odwala pofuna kupewa zovuta zilizonse (Kanyilmaz Gul et al, Asian Pacific Journal of Cancer Prevention, 2015), ngakhale maphunziro aposachedwa azachipatala sanawonetse zotsatira zoyipa pakuwongolera chotupa ndi zotsatira za kupulumuka ndi glutamine supplementation. (Kanyilmaz Gul et al, Clin Nutr., 2017) Chifukwa chake, ngakhale maphunziro omwe afotokozedwa mwachidule mubulogu ino akuwonetsa ubwino wa glutamine mu khansa ya m'mapapo, odwala ayenera kukambirana ndi dokotala wawo asanamwe mankhwala aliwonse a khansa yawo.
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.