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Pakafukufuku wocheperako yemwe anachitika ku China, ofufuza adayesa kugwiritsa ntchito Epigallocatechin-3-gallate (EGCG), flavonoid yomwe imapezeka mochulukira mu chakumwa chodziwika bwino - Tiyi wobiriwira, mwa odwala khansa yam'mero ndi chithandizo cha radiation chomwe chimayambitsa zovuta zakumeza (esophagitis). Iwo adapeza kuti EGCG ikhoza kukhala yopindulitsa pochepetsa chithandizo cha radiation chomwe chimayambitsa kumeza kwa odwala omwe amathandizidwa ndi mankhwala a chemoradiation kapena radiation popanda kuwononga mphamvu za mankhwalawa. Tiyi wobiriwira, yemwe nthawi zambiri amatengedwa ngati gawo lazakudya / zakudya zopatsa thanzi, atha kugwiritsidwanso ntchito kuchepetsa zotsatira zoyipa zomwe zimachitika chifukwa cha chemo mu esophageal. khansa.
Khansa ya Esophageal ndi Chithandizo cha Radiation Induced Esophagitis
Khansara yam'mimba ikuyerekezedwa kukhala yachisanu ndi chiwiri yomwe imayambitsa khansa Padziko lonse lapansi ndipo amawerengera 5.3% ya kufa kwa khansa padziko lonse lapansi (GLOOCAN, 2018). Ma radiation ndi chemoradiation (chemotherapy pamodzi ndi ma radiation) ndi mankhwala omwe amagwiritsidwa ntchito kwambiri pa khansa ya m'mimba. Komabe, mankhwalawa amalumikizidwa ndi zotsatira zoyipa zingapo kuphatikiza acute radiation induced esophagitis (ARIE). Esophagitis ndi kutupa kwa esophagus, minyewa yomwe imalumikiza pakhosi ndi m'mimba. Kuyambika kwa acute radiation-induced esophagitis (ARIE) nthawi zambiri kumachitika mkati mwa miyezi itatu pambuyo pa radiotherapy ndipo nthawi zambiri kumabweretsa zovuta / zovuta zomeza. Chifukwa chake, njira zosiyanasiyana zochepetsera zovuta zomeza zoyambitsidwa ndi ma radiation zikufufuzidwa chifukwa ndizofunikira kwa akatswiri a oncologist kuti azitha kuyang'anira bwino odwala omwe akhudzidwa.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Phunziro pa Impact ya Green Tea yogwira EGCG pa Radiation Treatment-Induced Esophagitis mu Khansa ya Esophageal
Epigallocatechin-3-gallate (EGCG) ndi flavonoid yokhala ndi antioxidant komanso anti-inflammatory properties ndipo imagwiritsidwanso ntchito pochepetsa chiopsezo cha khansa inayake. Ndi imodzi mwazinthu zambiri zomwe zimapezeka mu tiyi wobiriwira ndipo zimapezekanso mu tiyi woyera, oolong, ndi wakuda. Kafukufuku wachipatala wa gawo lachiwiri adachitidwa posachedwapa ndi ofufuza a ku Shandong Cancer Hospital ndi Institute ku China, kuti awone zotsatira za wobiriwira tiyi chigawo cha EGCG (kawirikawiri chimatengedwa ngati gawo la zakudya zopatsa thanzi) pa mankhwala a chemoradiation/radiation induced esophagitis (kumeza zovuta) mwa odwala khansa ya esophageal omwe adaloledwa pakati pa 2014 mpaka 2016 (Xiaoling Li et al, Journal of Medicinal Food, 2019). Odwala okwana 51 adaphatikizidwa mu kafukufukuyu, mwa odwala 22 adalandira chithandizo chamankhwala nthawi yomweyo (odwala 14 adalandira chithandizo ndi docetaxel + cisplatin ndikutsatiridwa ndi radiotherapy ndi 8 ndi fluorouracil + cisplatin wotsatiridwa ndi radiotherapy) ndipo odwala 29 adalandira chithandizo cha radiation ndipo adathandizidwa. kuyang'aniridwa mlungu uliwonse kwa acute radiation induced esophagitis (ARIE) / kumeza zovuta. Kuopsa kwa ARIE kudatsimikiziridwa pogwiritsa ntchito Radiation Therapy Oncology Group (RTOG) Score. Odwala omwe ali ndi giredi 1 RTOG adawonjezeredwa ndi 440 µM EGCG ndi ma RTOG atagwiritsa ntchito EGCG adafanizidwa ndi ziwerengero zoyambira (pamene adathandizidwa ndi ma radiation kapena chemoradiation).
Zotsatira zazikulu za kafukufukuyu zalembedwa pansipa (Xiaoling Li et al, Journal of Medicinal Food, 2019):
- Kuyerekeza kwa kuchuluka kwa RTOG mu sabata yoyamba, yachiwiri, yachitatu, yachinayi, yachisanu, ndi yachisanu ndi chimodzi pambuyo pa EGCG (tiyi yobiriwira yogwira) komanso sabata yoyamba ndi yachiwiri pambuyo pa radiotherapy ikuwonetsa kuchepa kwakukulu kwa zovuta zakumeza / ma radiation owopsa omwe amachititsa esophagitis. ARIE).
- Odwala 44 mwa 51 adawonetsa kuyankhidwa kwachipatala, ndi kuyankha kwa 86.3%, kuphatikiza 10 Kuyankha Kwathunthu ndi 34 Kuyankha Mwapang'ono.
- Pambuyo pa zaka 1, 2, ndi 3, chiwerengero cha kupulumuka chinapezeka kuti ndi 74.5%, 58%, ndi 40.5% motsatira.
Pomaliza: Tiyi Yobiriwira (EGCG) imachepetsa Kuvuta Kumeza mu Khansa ya Esophageal
Kutengera zomwe zapezedwa izi, ofufuzawo adatsimikiza kuti EGCG supplementation imachepetsa zovuta zomeza / esophagitis popanda kusokoneza mphamvu ya chithandizo cha radiation. Kumwa Tiyi yaukhondo monga gawo lazakudya zatsiku ndi tsiku zingathandize kuchepetsa vuto lakumeza, potero kuwongolera moyo wa odwala khansa yam'mero. Maphunziro azachipatala otere, ngakhale amachitidwa mwa odwala ochepa, akulonjeza ndikuthandizira kuzindikira njira zatsopano zothanirana ndi chemotherapy kapena radiation therapy yomwe imayambitsa zotsatirapo zake. Komabe, zotsatira za EGCG pakuchepetsa chithandizo cha radiation chomwe chinayambitsa esophagitis chiyenera kuyesedwa mowonjezereka ndikutsimikiziridwa mu phunziro lalikulu lachipatala lachisawawa ndi gulu lolamulira (gulu lolamulira linali likusowa mu phunziro lamakono) musanagwiritse ntchito ngati ndondomeko ya chithandizo.
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo komanso kuyang'ana njira zina zochiritsira khansa chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.