Mfundo
Pakadali pano pamankhwala okwera mtengo a khansa, mankhwala ambiri a khansa a FDA ndi EMA adalowa mumsika potengera malo omaliza, popanda umboni wopindulitsa pakupulumuka konse kapena moyo wabwino, monga akunenedwa ndi kafukufuku wazachipatala akuwunika kuvomerezedwa ndi mankhwala a khansa pakati 2008-2013: Kusanthula kopindulitsa kwa Mankhwala a Khansa.
Ngakhale efficacy watsopano khansa mankhwala akungoyenda pang'onopang'ono, mtengo wake ukukwera kwambiri kuposa kale. Pali kuyitanidwa komwe kukukulirakulira kuti mabungwe olamulira akweze chiwopsezo cha sayansi kuti avomereze mankhwala atsopano a khansa omwe pakali pano amatha kuwonetsa umboni wosamveka wogwira ntchito ndikulowa mumsika popanda umboni weniweni woti mankhwalawa athandizadi wodwalayo pakuwongolera. kupulumuka ndi khalidwe la moyo metrics. Pali njira zatsopano zowongolera zopangidwa ndi FDA, monga kuzindikirika, kuthamangitsa kapena kuthamangitsa njira, kuti apeze mankhwala oyika moyo pachiwopsezo kapena matenda osowa pamsika mwachangu kutengera zomwe zachitika; koma pali maphunziro otsatila omwe adalamulidwa kuti awonetse umboni wakuchita bwino. Lipoti la 2009 Government Accountability Office (GAO) lidadzudzula US FDA chifukwa cholephera kutsatira zomwe amalonjeza potsatsa malonda pamankhwala omwe amavomerezedwa pazifukwa zodziyimira pawokha (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)61932 -2/mawu onse). Choncho lero, kutengera kusanthula kwa mankhwala ovomerezeka m'zaka khumi zapitazi, pali nkhawa yowonjezereka yoyika mankhwala okwera mtengo kwambiri, omwe ali ndi zida zachipatala zomwe sizimapangitsa kuti kupulumuka kukhale bwino.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Kupulumuka Phindu la Mankhwala Ovomerezeka a Khansa
Pali maphunziro awiriwa, imodzi yoyang'ana mankhwala omwe amavomerezedwa pakati pa 2008-2012 ndi US FDA (Kim ndi Prasad, JAMA Intern Med., 2015) ndi pakati pa 2009-2013 ndi EMA (European Medical agency) (Davis C et al, BMJ., 2017), onse akuwonetsa za pamwambapa. Kafukufuku wa FDA adati 36 ya 54 (67%) yavomerezedwe ya mankhwala a khansa idakhazikitsidwa pomalizira pake monga kuchepa kwa chotupa kapena masiku omwe wodwala amakhalabe wopanda matenda (kupitiriza kupulumuka kwaulere). Pambuyo pazaka 4.4 zakutsata mankhwala a khansa ovomerezeka a FDA, 5 yokha mwa 36 (14%) yomwe idavomerezedwa idawonetsa kupulumuka konse, pomwe 31 (86%) mwa awa adalephera kapena alibe chidziwitso chilichonse chokhudza kupulumuka. Pakuwunika kwa EMA mankhwala a khansa omwe adavomerezedwa pakati pa 2009-2013, panali mankhwala 48 omwe adavomerezedwa kuti apite kumsika kwa zisonyezo za khansa 68 ndipo 35 (51%) mwa awa adawonetsa kusintha pakukhala ndi moyo kapena moyo wabwino. Phindu lopulumuka komanso tanthauzo la mankhwalawa lidaweruzidwa pogwiritsa ntchito ESMO-MCBS (European Society for Medical Oncology Magnitude of Clinical Benefit Scale), yomwe ndi njira yokhayo yomwe imagwiritsidwa ntchito poyesa kukula kwa kufunika kwamankhwala komanso kuvomerezeka kwa mankhwala a khansa. Chomwe chiri chodetsa nkhawa kwambiri ndikuti ngakhale kuthekera kokayikitsa kwamankhwala ambiri ovomerezeka a khansa pamsika, mitengo yake imapitilizabe kukwera modetsa nkhawa.
Chitsanzo chapadera cha izi ndi mankhwala a Regorafenib omwe amapatsidwa mankhwala kuti azitha mochedwa khansa yoyipa, khansa ya m'matumbo kapena rectum yomwe ndi khansa yachitatu ku United States (American Cancer Society). Regorafenib adapatsidwa kalasi ya 1 ndi chida cha ESMO-MCBS chomwe chimatanthawuza kuti chimakhala ndi maubwino azachipatala kapena phindu lililonse pamoyo wawo (Davis C et al, BMJ., 2017). Kuphatikiza apo, mankhwalawa ndi okwera mtengo kwambiri osagwira ntchito pamitengo yokwera kwambiri komanso phindu lochulukirapo lazachipatala (Cho SK et al, Khansa Yachipatala Yachipatala., 2018). Ndipo komabe, idayambitsidwa pamsika ngati mankhwala 'opambana' a khansa yoyipa yam'mimba mochedwa.
Kwenikweni, blog iyi idapangidwa kuti ipangitse odwala ndi okondedwa awo kudziwa zenizeni zenizeni khansa mankhwala ndi kuwalimbikitsa kuti afufuze mtengo wa phindu lake, aganizire njira zawo zonse za chithandizo ndi kusankha mwanzeru m'malo motsatira mwachimbulimbuli msika wamakono womwe umalimbikitsa njira zatsopano komanso zodula.
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.