o ka Naauao
ʻO kēia blog kahi hōʻuluʻulu o nā noiʻi lapaʻau a me nā hopena e hōʻike i ka hui ʻana o ka lawe ʻana i ka huaora/multivitamin a me ka pilikia maʻi kanesa a me kekahi mau ʻike kumu e pili ana i nā kumu meaʻai kūlohelohe o nā huaora like ʻole. ʻO ka hopena koʻikoʻi mai nā haʻawina like ʻole, ʻo ka lawe ʻana i nā huaora mai nā kumu meaʻai kūlohelohe he mea maikaʻi ia no mākou a hiki ke hoʻohui ʻia i ʻāpana o kā mākou meaʻai / meaʻai i kēlā me kēia lā, ʻoiai ʻaʻole kōkua ka hoʻohana ʻana i ka multivitamin supplementation nui a ʻaʻole hoʻohui i ka waiwai nui i ka hāʻawi ʻana i nā anti- nā pōmaikaʻi ola kino. Hiki ke hoʻopili ʻia ka hoʻohana nui ʻana o nā multivitamins me ka hoʻonui Ka maʻi 'aʻai pilikia a hiki ke hoʻopilikia. No laila pono e hoʻohana wale ʻia kēia mau mea hoʻohui multivitamin no ka mālama ʻana a i ʻole ka pale ʻana ma muli o ka ʻōlelo a nā kauka lapaʻau - no ke ʻano kūpono a me ke kūlana.
ʻO nā huaora nā meaola kūpono mai nā meaʻai a me nā kumuwaiwai kūlohelohe e pono ai i ko mākou kino. Hiki i ka hemahema o nā wikamina kikoʻī ke hana i nā hemahema koʻikoʻi i hōʻike ʻia ma ke ʻano he ʻano ʻokoʻa. Hoʻopili ʻia kahi papaʻai kaulike, olakino me ka lawa kūpono o nā meaʻai a me nā wikamina me ka hoʻemi ʻia o ka make o nā maʻi maʻi maʻi a me nā maʻi ʻaʻai. Pono ke kumu waiwai no nā meaʻai a mākou e ʻai ai, akā i nā manawa wikiwiki e noho nei mākou, ʻo kahi lā o ka multivitamin kahi pani no kahi papaʻai momona maikaʻi.
ʻO kahi mea multivitamin supplement i ka lā i lilo i mea maʻamau no nā poʻe he nui ma ka honua holoʻokoʻa ma ke ʻano he ala kūlohelohe e hoʻonui ai i ko lākou olakino a maikaʻi a pale i nā maʻi e like me ka maʻi ʻaʻai. Ke piʻi nei ka hoʻohana o Multivitamins i ka hanauna pēpē pēpē boomer no nā pono olakino a me ke kākoʻo ʻana i ka olakino maʻamau. Manaʻo ka hapanui o ka lawe ʻana i ka wikamina kiʻekiʻe he anti-ʻelemakule, hoʻonui ʻana i ka palekana a me ka pale ʻana i ka maʻi elixir, ʻoiai inā ʻaʻole maikaʻi, ʻaʻole hiki ke hana ʻino. Aia ka manaʻoʻiʻo ʻoiai nā huaʻai mai nā kumuwaiwai kūlohelohe a paipai i ke olakino maikaʻi, ʻoi aku ka nui o kēia mau mea i lawe ʻia ma ke ʻano he mea hoʻohui pono e pōmaikaʻi wale ai kāua. Me ka laulā a me ka nui o ka hoʻohana ʻia ʻana o nā wikamina a me nā multivitamins a puni nā heluna o ka honua, ua nui nā loiloi hoʻokolohua retrospective observational i nānā i nā hui o nā wikamina like ʻole me kā lākou hana pale maʻi ʻaʻai.
Nā Kumuwaiwai vs.
ʻO kahi noiʻi hou na ke Kula ʻo Friedman a me ke Kula Lapaʻau o ke Kulanui ʻo Tufts i nānā i nā pono kūpono a me nā hōʻino o ka hoʻohana ʻana i ka huaora. Nānā nā kānaka noiʻi i ka ʻikepili mai ka 27,000 mau mākua olakino i 20 mau makahiki a ʻoi paha. Ua loiloi ʻia ke aʻo ʻana i ka lawe ʻana o ka huaora momona a i ʻole nā meaʻai kūlohelohe a i ʻole nā mea hoʻohui a me ka hui pū ʻana me nā mea make āpau āpau, ka make e ka maʻi maʻi maʻi a maʻi a maʻi paha. (Chen F et al, Nā Annals o Int. Med, 2019)
Ua loaʻa ka noiʻi i nā pōmaikaʻi ʻoi aku ka nui o ka loaʻa ʻana o ka huaora momona mai nā kumuwaiwai kūlohelohe ma kahi o nā mea hoʻopiha. ʻO ka lawa kūpono o ka Vitamin K a me ka Magnesium mai nā meaʻai i pili me ka haʻahaʻa o ka make. ʻO ka lawe nui ʻana o ka calcium mai nā mea hoʻopihapiha, ʻoi aku ma mua o 1000 mg / lā, ua pili pū me ka nui o ka make o ka maʻi ʻaʻai. Hoʻohana ʻia nā mea hoʻohui Vitamin D i kēlā me kēia kanaka i ʻole nā hōʻailona o ka hemahema ʻo Vitamin D e pili pū me ka hoʻonui ʻana i ka make o ka maʻi ʻaʻai.
Aia kekahi mau noiʻi hoʻokolohua ʻē aʻe i loiloi i ka hui o ka hoʻohana ʻana i nā huaola kikoʻī a i ʻole nā multivitamin supplement and pilikia o ka maʻi ʻaʻai. E hōʻuluʻulu mākou i kēia ʻike no nā wikamina kikoʻī a i ʻole multivitamins me kā lākou kumuwaiwai kūlohelohe, a me nā hōʻike ʻepekema a me nā lāʻau lapaʻau no kā lākou pono a me nā pilikia me ka maʻi ʻaʻai.
ʻO ka wikamina A - nā kumuwaiwai, nā pono a me nā pilikia i ka maʻi ʻaʻai
Nā kumuhana: ʻO ka Wikamina A, kahi huaola momona hiki ke hoʻoheheʻe ʻia, kahi mea pono nui e kākoʻo i ka ʻike maʻamau, ka ʻili olakino, ka ulu a me ka hoʻomohala ʻana o nā hunaola, hoʻomaikaʻi i ka hana pale a me ka ulu ʻana o ka fetal. ʻOiai he mea waiwai nui, ʻaʻole hana ʻia ka Wikamina A e ke kino o ke kanaka a loaʻa ʻia mai kā mākou papaʻai olakino. ʻIke ʻia ia i nā kumuwaiwai holoholona e like me ka waiū, nā hua manu, ka ate a me nā aʻa iʻa-akepa i ke ʻano o retinol, ke ʻano o Vitamin A. Loaʻa ʻia i nā kumuwaiwai e like me kāloka, ʻuala, spinach, papaya, mango a me ka paukena i ke ʻano o carotenoids, nā mea provitamin A i hoʻohuli ʻia e retinol e ke kino o ke kanaka i ka wā o ka digestion. ʻOiai ʻo ka loaʻa ʻana o ka Vitamin A i ke olakino i ko mākou olakino ma nā ʻano he nui, ua nānā ʻia nā noiʻi lapaʻau he nui i ka hui ma waena o ka wikamina A a me nā ʻano ʻano maʻi ʻaʻai like ʻole.
Ka hui o ka wikamina A me ka hoʻonui i ka makaʻu o ka maʻi ʻaʻai
Ua hōʻike ʻia kekahi o nā noiʻi hoʻokolohua retrospective retrospective hou i hiki i nā mea hoʻopihapiha e like me beta-carotene ke hoʻonui hou aʻe i ka makaʻu o ka maʻi ʻaʻai pūpū ʻoi loa i nā mea puhipaka a me nā poʻe i loaʻa ka mōʻaukala koʻikoʻi.
I hoʻokahi noiʻi, ua noiʻi nā kānaka noiʻi mai ka papahana Thoracic Oncology ma Moffitt Cancer Center ma Florida, i ka pilina ma o ka nānā ʻana i ka ʻikepili ma nā mea he 109,394 a ua hoʻoholo ʻia "ma waena o nā poʻe puhipaka o kēia manawa, ua ʻike nui ʻia ka hoʻopili beta-carotene me ka hoʻonui nui ʻana o ka maʻi maʻi ʻaʻai '(Tanvetyanon T et al, maʻi ʻaʻai, 2008).
Ma waho o kēia noi ʻana, ua hana pū kekahi nā noiʻi ma mua i nā kāne puhipaka, e like me CARET (Carotene a me Retinol Efficacy Trial) (Omenn GS et al, New Engl J Med, 1996), a me ka ATBC (Alpha-Tocopherol Beta-Carotene) Study Prevent Cancer. (Pūʻulu Haʻawina Kālepa Kālepa o ATBC, New Engl J Med, 1994), ua hōʻike pū ʻia ka lawe ʻana i nā kaha kiʻekiʻe o ka Huaora A ʻaʻole wale i pale aku i ka maʻi ʻaʻa maʻi, akā ua hōʻike i ka piʻi nui ʻana o ka hopena o ka maʻi ʻaʻa maʻi ma waena o ka poʻe i hoʻopaʻa haʻawina.
I loko o kahi loiloi ʻē aʻe o 15 ʻokoʻa noiʻi noiʻi i paʻi ʻia i ka puke pai ʻAmelika o Clinical Nutr i 2015, ma kahi o 11,000 mau hihia i kālailai ʻia, e hoʻoholo ai i ka hui o nā pae o nā Vitamins a me ka maʻi ʻaʻai. I loko o kēia laʻana nui loa, ua hoʻopili maikaʻi ʻia nā pae o retinol me ka maʻi maʻi ʻaʻai prostate. (ʻO Key TJ et al, ʻo Am J Clin. Nutr., 2015)
ʻO kahi anamanaʻo nānā ma luna o nā mea komo o 29,000 i hōʻiliʻili ʻia ma waena o 1985-1993 mai ke aʻo ʻana i ka maʻi ʻaʻai ATBC, ua hōʻike ʻia ma ka ukali ʻia ʻana o 3 makahiki, ua hoʻonui ʻia ka makaʻu o ka maʻi ʻaʻai prostate (Menul AM et al, Am ʻO J Epidemiol, 2011). ʻO kahi loiloi hou loa o ka NCI like i kipaku ʻia i ka mālama ʻana i ka maʻi ʻaʻai ATBC me ka ukali ʻana i 2012, ua hōʻoia i nā ʻike mua o ka hui o ke kiʻekiʻe o ka serum retinol konsentration me ka hoʻonui ʻana i ka makaʻu o ka maʻi ʻaʻai prostate (Hada M et al, Am J Epidemiol, 2019).
No laila, ʻoiai he mea nui ka beta-carotene maoli no ka papaʻai kaulike, hiki ke lilo i mea nui loa i ka lawe ʻana i loko o nā mea kōkua multivitamin i mea weliweli a ʻaʻole paha e kōkua pinepine i ka pale ʻana i ka maʻi ʻaʻai. E like me ka hōʻike ʻana o nā noiʻi, hiki i ka lawe nui ʻana o retinol a me carotenoid nā mea hoʻohui ke hiki ke hoʻonui i ka makaʻu o nā maʻi ʻino e like me ka maʻi ʻaʻa maʻi ma nā poʻe puhipaka a me nā maʻi ʻaʻai prostate i nā kāne.
Nā Mea ʻai e ʻAi ai Ma hope o ka ʻike maʻi ʻaʻai!
ʻAʻohe ʻelua maʻi ʻaʻai. E hele i waho o nā kulekele meaʻai maʻamau no kēlā me kēia kanaka a hoʻoholo i nā koho pilikino e pili ana i ka meaʻai a me nā mea hoʻopihapiha me ka hilinaʻi.
Ka hui o ka wikamina A me ka hōʻemi o ka maʻi ʻaʻai
Ua nānā ʻia kahi noiʻi hoʻokolohua i ka ʻikepili e pili ana i ka lawe ʻana o ka Vitamin A a me ka makaʻu o ka camona squamous cell carcinoma (SCC), kahi ʻano maʻi ʻaʻai o ka ʻili, mai nā mea komo i ʻelua mau noiʻi nānā lōʻihi lōʻihi. ʻO nā haʻawina i hoʻopaʻa ʻia i ka Haʻawina Ola Haumāna (NHS) a me ka Haʻawina Hoʻomau Haumāna Ola (HPFS). ʻO Cutaneous squamous cell carcinoma (SCC) ka lua o nā ʻano maʻamau o ka maʻi ʻaʻai ʻili me ka helu o ka helu o 7% a 11% i United States. Ua komo ka noiʻi i ka ʻikepili mai nā wahine 75,170 US i komo i loko o ka noiʻi NHS, me ka makahiki o 50.4 mau makahiki, a me 48,400 US mau kāne i komo i ke aʻo ʻana i ka HPFS, me ka makahiki 54.3 mau makahiki. (Kim J et al, JAMA Dermatol., 2019).
ʻO nā ʻike nui o ke aʻo ʻana ua pili ka lawe ʻana o ka Vitamin A me ka haʻahaʻa o ka maʻi ʻaʻai (SCC). ʻO ka hui i loaʻa ka awelika kiʻekiʻe loa o kēlā me kēia lā Vitamin A ʻai he 17% hoʻemi i ka makaʻu o ka cccueus SCC ke hoʻohālikelike ʻia me ka hui i hoʻopau i ka mea liʻiliʻi ʻo Vitamin A. Loaʻa ka hapanui mai nā kumuʻai a ʻaʻole nā papaʻai papaʻai. ʻO ke kiʻekiʻe o ka loaʻa ʻana o ka wikamina A, retinol, a me nā carotenoids, i loaʻa maʻamau mai nā huaʻai a me nā mea kanu like ʻole, i pili me ka haʻahaʻa o ka SCC.
ʻO nā kumuwaiwai, nā pono a me nā pilikia o ka Vitamin B6 a me B12 i ka maʻi ʻaʻai
kumu : ʻO ka Vitamin B6 a me B12 nā wikamina hiki ke hoʻoheheʻe wai i ʻike pinepine ʻia i nā meaʻai he nui. ʻO ka Vitamin B6 he pyridoxine, pyridoxal a me nā hui pyridoxamine. He mea pono nui ka nutrient a he coenzyme no nā hopena metabolic he nui i loko o kā mākou kino, he hana i ka hoʻomohala ʻike, hoʻokumu hemoglobin a me ka hana pale. ʻO nā meaʻai momona a ka Vitamin B6 e komo pū me nā iʻa, moa, tofu, pipi, uala, maiʻa, ʻuala, avocados a me pistachios.
ʻO ka Vitamin B12, ka mea i ʻike ʻia ʻo cobalamin, kōkua i ka mālama ʻana i nā aʻalolo a me nā huna koko a pono no ka hana ʻana iā DNA. ʻIke ʻia kona hemahema o ka huaʻai B12 e hoʻokumu i ka anemia, nāwaliwali a me ka luhi a no laila he mea nui ia i kā mākou papaʻai i kēlā me kēia lā me nā meaʻai i loaʻa ka Vitamin B12. ʻOkoʻa, hoʻohana ka poʻe wikamina B a i ʻole nā B-complex a i ʻole nā multivitamin e hoʻopili i kēia mau huaora. ʻO nā kumuwaiwai o ka wikamina B12 nā iʻa a me nā huahana holoholona e like me ka waiū, ka ʻiʻo a me nā hua a me nā mea kanu a me nā mea kanu e like me ka tofu a me nā huahana soy fermented a me nā limu.
Ka hui o ka Vitamin B6 me ka maʻi ʻaʻai maʻi ʻaʻai
ʻAʻole hōʻike ʻia kahi helu liʻiliʻi o nā hoʻokolohua hoʻokolohua i pau a hiki i kēia lā i hiki i ka huakino B6 ke hoʻemi i ka make a kōkua i ka pale ʻana i ka maʻi ʻaʻai. ʻO kahi kālailai o ka ʻikepili mai ʻelua mau noiʻi hoʻokolohua nui ma Nolewai i loaʻa kahi pilina ma waena o ka huaʻai B6 supplementation a me ka maʻi ʻaʻai a me ka make ʻana. (Ebbing M, et al, JAMA, 2009) No laila, ʻo nā hōʻike no ka hoʻohana ʻana o ka wikamina B6 e pale a mālama ʻana paha i ka maʻi ʻaʻai a hōʻemi paha ʻino e pili ana i ka chemotherapy ʻaʻole maopopo a paʻa paha. ʻOiai, 400 mg o ka wikamina B6 hiki ke hoʻokō i ka hōʻemi ʻana i ka hanana o ka maʻi lima wāwae, kahi hopena chemotherapy. (Chen M, et al, PLoS Hoʻokahi, 2013) ʻO ka supplementation o ka wikamina B6, ʻaʻole i hōʻike ʻia e hoʻonui i ka makaʻu o nā maʻi ʻaʻai.
Ka hui o ka Vitamin B12 me ka maʻi ʻaʻai maʻi ʻaʻai
Teia ke piʻi aʻe nei nā hopohopo e pili ana i ka hoʻohana lōʻihi o ka lāʻau Vitamin B12 kiʻekiʻe a me kona hui pū ʻana me ka makaʻu o ka maʻi ʻaʻai. Ua lawe ʻia nā noiʻi like ʻole a me nā kālailai e noiʻi i ka hopena o ka lawe ʻana o ka Vitamin B12 i ka maʻi ʻaʻai.
ʻO kahi hoʻokolohua hoʻokolohua hoʻokolohua, i kapa ʻia ka B-PROOF (B Vitamins no ka Prevent o Osteoporotic Fractures) i hoʻāʻo ʻia, i hana ʻia ma Netherlands e nānā i ka hopena o ka hoʻopili ʻana i kēlā me kēia lā me ka wikamina B12 (500 μg) a me ka folic acid (400 μg), no 2 i nā makahiki 3, ma ka hanana haʻi. Ua hoʻohana ʻia ka ʻikepili mai kēia noiʻi e nā kānaka noiʻi e noiʻi hou i ka hopena o ka hoʻoliʻiliʻi wā lōʻihi o ka Vitamin B12 i ka maʻi ʻaʻai. Hoʻopili ʻia ka ʻikepili me ka ʻikepili mai nā poʻe komo 2524 o ka hoʻāʻo B-PROOF a ua ʻike ʻia ua pili ka lōʻihi o ka waikawa folic a me ka huaʻai B12 me ka pilikia nui o ka maʻi ʻaʻai āpau a me ka nui o ka makaʻu o ka maʻi ʻaʻa kala. Eia nō naʻe, ʻōlelo nā kānaka noiʻi e hōʻoia ana i kēia loaʻa ʻana i nā noi nui aku, i mea e hoʻoholo ai inā e kaupalena ʻia ka hoʻoliʻiliʻi Vitamin B12 i nā mea wale nō me ka hemahema B12 i ʻike ʻia (Oliai Araghi S et al, Cancer Epidemiol Biomarkers Prev., 2019).
I loko o kahi noiʻi ʻē aʻe i paʻi ʻia i hala koke aku nei, ua kālailai nā kānaka noiʻi i nā hopena mai ka 20 heluna kanaka i hoʻopaʻa ʻia a me nā ʻikepili mai 5,183 mau maʻi ʻaʻa puʻupuʻu a me kā lākou kūlike i nā mana o 5,183, e loiloi ai i ka hopena o ka nui o ka vitamini B12 i ka hopena o ka maʻi ʻaʻai ma o nā ana pono o ka hoʻolaha ʻana i ka wikamina B12 i nā laʻana koko pre-diagnostic. Ma muli o kā lākou kālailai ʻana, ua hoʻoholo lākou e pili ana nā kiʻekiʻe o ka vitamona B12 me ka nui o ka hopena o ka maʻi ʻaʻai a no nā pae pālua o ka Vitamin B12, ua hoʻonui ʻia ka pilikia e ~ 15% (Fanidi A et al, Int J Cancer., 2019).
Hōʻike nā ʻike nui mai kēia mau noiʻi āpau i ka hoʻohana wā lōʻihi o ka lāʻau kiʻekiʻe ʻO ka Vitamin B12 e pili pū me ka hoʻonui ʻia o nā maʻi ʻaʻai e like me ka maʻi ʻaʻa kala a me ka maʻi ʻaʻa maʻi. ʻOiai ʻaʻole ia he manaʻo e hemo loa iā mākou ka Vitamin B12 mai kā mākou papaʻai, ʻoiai mākou e pono ai i ka nui o ka Vitamin B12 ma ke ʻano he ʻāpana o ka papaʻai maʻamau a i ʻole he hemahema B12. ʻO ka mea a mākou e pono ai e hōʻalo i ka nui o ka huaora B12 supplement (ma ʻō aku o ka pae kūpono).
Nā Kumuwaiwai, Nā Pōmaikaʻi a me nā pilikia o ka Vitamin C i ka maʻi ʻaʻai
kumu : Vitamin C, ʻo ia hoʻi ʻo ascorbic acid, kahi wai hiki ke hoʻoheheʻe ʻia i ka wai, nā mea waiwai nui i loaʻa i nā kumu meaʻai he nui. Loaʻa iā ia nā waiwai antioxidant e kōkua i ka pale ʻana i kā mākou pūnaewele mai ka hōʻino ʻia e nā radical manuahi. ʻO nā radical manuahi kahi mea hoʻohui i hana ʻia i ka wā e metabolize ai ko mākou kino i ka meaʻai a hana ʻia hoʻi ma muli o ke kaiapuni e like me ka uahi paka ʻana, ka haumia ea a me nā kukuna ultraviolet i ka lā. Pono ʻia ka Vitamin C e ke kino e hana i collagen e kōkua i ka hōʻeha ʻana i ka ʻeha; a kōkua pū i ka mālama ʻana i ka ikaika a ikaika hoʻi ka pale pale. ʻO nā kumuwaiwai waiwai i loko o ka Vitamin C me nā hua citrus e like me ka ʻalani, ka huaʻakai a me ka lemona, nā pepa ʻulaʻula a me nā ʻōmaʻomaʻo, nā hua kiwi, nā cantaloupe, nā strawberry, nā mea kanu kolio, mango, pepaya, nā pineapa a me nā hua a me nā mea kanu ʻē aʻe.
ʻO ka ʻAhahui Pono o ka Wikamina C me ka Pilikia Ka maʻi ʻaʻai
Ua nui nā noiʻi hoʻokolohua e noiʻi ana i nā hopena maikaʻi o ka hoʻohana ʻana i ka lāʻau kiʻekiʻe Vitamin Vitamin i nā ʻano maʻi ʻaʻai. ʻO nā hoʻokolohua hoʻokolohua hoʻolālā maikaʻi o ka Vitamin C e hoʻohana ai i ke ʻano o kahi kōkua waha i loaʻa ʻole nā pono no ka poʻe me ka maʻi ʻaʻai. Eia nō naʻe, i kēia mau lā, ua loaʻa ʻia ka Vitamin C me ka intravenous e hōʻike i ka hopena maikaʻi e like ʻole me ka mahele ma ka waha. Ua loaʻa ka palekana o kā lākou infusions intravenous a me ka hoʻomaikaʻi ʻana i ka efficacy a me ka hoʻohaʻahaʻa haʻahaʻa ke hoʻohana ʻia me nā radiation a me nā chemotherapy.
Ua hana ʻia kahi noiʻi noiʻi i nā mea maʻi maʻi maʻi glioblastoma (GBM) hou, e loiloi ai i ka palekana a me ka hopena o ka lāʻau lāʻau ascorbate (Vitamin C) infusion, hāʻawi ʻia me ke kūlana o ka mālama mālama ʻana i ka radiation a me temozolomide (RT / TMZ) no GBM. (ʻO Allen BG et al, ʻo Clin Cancer Res., 2019) Hōʻike nā hopena o kēia noi i ka hoʻokomo ʻana i ka lāʻau kiʻekiʻe C Vitamin a ascorbate paha i nā mea maʻi maʻi ʻaʻai GBM i hoʻonui i ko lākou ola āpau mai 12 mau mahina a 23 mau mahina, keu hoʻi i nā kumuhana i ʻike ʻia kahi māka o ka wānana maikaʻi ʻole. 3 o nā kumuhana 11 e ola nei i ka manawa o ke kākau ʻana i kēia noi ma 2019. ʻO nā hopena maikaʻi ʻole i ʻike ʻia e nā kumuhana he waha maloʻo a me nā haʻalulu e pili ana i ka inforbate infusion, ʻoiai nā hopena ʻē aʻe i ʻoi aku ka nui o ka luhi, nausea a ʻo nā hanana hopena hematological e pili ana me TMZ a me RT i hoʻemi ʻia.
Ua hōʻike pū kekahi ka lāʻau Vitamin C i kahi hopena synergistic me kahi lāʻau hypomethylating (HMA) Decitabine, no ka leukemia myeloid koʻikoʻi. He haʻahaʻa ka pane no ka lāʻau HMA, ma kahi o 35-45% (Welch JS et al, New Engl. J Med., 2016). Ua hoʻokolohua kahi noiʻi hou i hana ʻia ma Kina i ka hopena o ka hoʻohui ʻana i ka Wikamina C me Decitabine i nā maʻi maʻi ʻaumākua me AML. Ua hōʻike ʻia kā lākou hopena ua loaʻa nā maʻi maʻi ʻaʻai i lawe iā Decitabine i hui pū ʻia me ka Vitamin C i kahi kiʻekiʻena remission 79.92% kiʻekiʻe me 44.11% o ka poʻe i lawe wale iā Decitabine (Zhao H et al, Leuk Res., 2018) ʻO ke kumu ʻepekema ma hope o ka hoʻomaikaʻi ʻana o ka Vitamin C i ka Decitabine pane i nā mea maʻi maʻi ʻaʻa ʻaʻole ia he hopena wale nō.
Hōʻike kēia mau noiʻi ʻaʻole hiki i nā lāʻau nui Vitamin C infusions ke hoʻomaikaʻi wale i ka hoʻomanawanui therapeutic o ka maʻi ʻaʻai chemotherapy, akā he hiki no ka hoʻonui ʻana i ke ola o nā mea maʻi a me ka hōʻemi ʻana. nā meaʻona o ka hoʻoponopono radiation a me ka chemotherapy. ʻAʻole i lawe maikaʻi ʻia ka lāʻau huaola C i ka waha no ka hoʻokō ʻana i nā kiʻekiʻe kiʻekiʻe me ka infusion vitamin C intravenous, no laila ʻaʻole i hōʻike ʻia nā pōmaikaʻi. Hōʻike ka infusion vitamin C (ascorbate) kiʻekiʻe i ka hoʻohiki i ka hoʻohaʻahaʻa ʻana i nā mea ʻino o nā chemotherapies e like me gemcitabine, carboplatin a me paclitaxel i nā maʻi pancreatic a me ovarian. (Welsh JL et al, Cancer Chemother Pharmacol., 2013; Ma Y et al, Sci. Unuhi. Med., 2014)
Nā Kumuwaiwai, Nā Pōmaikaʻi a me nā pilikia o ka Vitamin D i ka maʻi ʻaʻai
kumu : ʻO ka Vitamin D kahi meaʻai e pono ai i ko mākou kino e mālama i nā iwi ikaika ma ke kōkua ʻana i ka omo ʻana i ka calcium mai nā meaʻai a me nā mea hoʻohui. Pono pū ʻia hoʻi no nā hana o ke kino ʻē aʻe e like me ka neʻe ʻana o nā mākala, hōʻailona neura a me ka hana ʻana o kā mākou ʻōnaehana pale kaua e hakakā i nā maʻi. ʻO nā kumuwaiwai waiwai i loko o ka Wikamina D he mau iʻa momona e like me ka salemona, tuna, mackerel, ʻiʻo, nā hua manu, nā hua waiū, nā mea kanu. Hana pū ko mākou kino i ka Vitamin D ke hōʻike pololei ʻia ka ʻili i ka lā.
Ka hui o ka wikamina D me ka maʻi ʻaʻai maʻi ʻaʻai
Ua hana ʻia kahi noiʻi hoʻokolohua prospective e hoʻoponopono i ka nīnau inā kōkua ka mea kōkua Vitamin D i ka pale ʻana i ka maʻi ʻaʻa. ʻO ka hoʻokolohua hoʻokolohua VITAL (VITamin D a me omegA-3 hoʻokolokolo) (NCT01169259) kahi hoʻokolohua āpau, prospective, randomized, me nā hopena i paʻi ʻia ma ka New England Journal of Medicine (Manson JE et al, New Engl J Med., 2019).
Aia he 25,871 i komo i loko o kēia noi i hui pū ʻia me nā kāne 50 makahiki a ʻoi a me nā wahine 55 a ʻoi paha makahiki. Hoʻokaʻawale ʻokoʻa ʻia nā mea komo i kahi hui e lawe ana i ka lāʻau Vitamin D3 (cholecalciferol) o 2000 IU i kēlā me kēia lā, ʻo ia ka 2-3 mau manawa i hāʻawi ʻia i ka papaʻai papaʻai. ʻAʻole i lawe ka hui placebo i kekahi mea kōkua Vitamin D. ʻAʻohe o nā poʻe i kākau inoa ʻia i loaʻa ka moʻolelo mua o ka maʻi ʻaʻai.
ʻO nā hopena o ka noi VITAL ʻaʻole i hōʻike i ka ʻokoʻa helu nui i ka ʻike maʻi ʻaʻai ma waena o nā hui ʻo Vitamin D a me placebo. No laila, ʻaʻole pili ka lāʻau kūpona Vitamin D me ka haʻahaʻa o ka maʻi ʻaʻai a i ʻole ka hopena haʻahaʻa o ka maʻi ʻaʻai. No laila, ke hōʻike ākea nei kēia ana ākea, ʻike maʻamau ʻia hiki ke kōkua ʻia ka lāʻau kō Vitamin D kiʻekiʻe me nā kūlana pili i ka iwi akā ʻaʻole e hoʻohui ka hoʻonui nui ʻana i ka waiwai mai kahi kuana pale maʻi maʻi maʻi.
Nā Kumuwaiwai, Nā Pōmaikaʻi a me nā pilikia o ka Wikamina E i ka maʻi ʻaʻai
kumu : Vitamin E kahi hui o nā momona momona momona i loaʻa i loko o nā meaʻai he nui. Hana ʻia ia i nā hui ʻelua o nā kemika: tocopherols a me tocotrienols, me ka mea i lilo i kumu nui no ka wikamina E i kā mākou papaʻai. ʻO nā waiwai antioxidant o ka wikamina E kōkua i ka pale ʻana i kā mākou mau pūnaewele mai ka hōʻino ʻana i hopena ʻia e nā radical free reactive a me ka stress oxidative. Pono ʻia no nā pono olakino lehulehu mai ka mālama ʻana i ka ʻili i ka olakino o ka puʻuwai a me ka lolo. ʻO nā meaʻai e waiwai ana i ka Wikamina E, ʻo ia ka aila kulina, nā aila mea kanu, ka aila pāma, nā ʻalemona, nā hazelnut, nā pinenuts, nā ʻano pua sunflower me nā hua ʻē aʻe a me nā mea kanu. ʻO nā meaʻai kiʻekiʻe aʻe ma tocotrienols pākī laiki, ʻoka, rai, bale a me ka aila pāma.
Ka hui o ka wikamina E me ka maʻi ʻaʻai maʻi ʻaʻai
Ua hōʻike ʻia nā noiʻi lapaʻau lehulehu i ka hoʻonui ʻia o ka maka maʻi ʻaʻai me nā kiʻina kiʻekiʻe o ka Vitamin E.
ʻO kahi noiʻi e pili ana i nā neuro oncology a me nā neurosurgery ʻokoʻa ma waena o nā haukapila ʻo US i kālailai ʻia i ka ʻikepili ninaninau ʻia mai nā maʻi he 470 i mālama ʻia ma hope o ka ʻike ʻia ʻana o ka maʻi ʻaʻai lolo glioblastoma multiforme (GBM). Ua hōʻike ʻia nā hopena i loaʻa i nā mea hoʻohana Vitamin E a kiʻekiʻe make ke hoʻohālikelike ʻia i kēlā mau maʻi maʻi ʻaʻai ʻole i hoʻohana i ka Wikamina E. (Mulphur BH et al, Neurooncol Pract., 2015)
I loko o kahi noi ʻē aʻe mai Suetena a me Ke Keʻena Kanaka maʻi o Norewai, ua hana nā mea noiʻi i kahi ala ʻokoʻa i ka hoʻoholo ʻana i nā kumu pilikia no ka maʻi ʻaʻai lolo, glioblastoma. Lawe lākou i nā hōʻailona serum a i 22 mau makahiki ma mua o ka hōʻike glioblastoma a hoʻohālikelike i nā metabolite concentrations o nā sample serum o nā mea i hoʻomohala i ka maʻi ʻaʻai mai ka poʻe i ʻole. Ua loaʻa iā lākou ka nui o ke kiʻekiʻe o ke kahe o ka Vitamin E isoform alpha-tocopherol a me gamma-tocopherol i nā hihia i ulu i ka glioblastoma. (Bjorkblom B et al, Oncotarget, 2016)
Ua hana ʻia kahi Selenium nui loa a me ka Vitamin E Cancer Prevent Trial (SELECT) ma luna o 35,000 mau kāne e loiloi ai i ka pilikia o ke kōkua o Vitamin E. Hana ʻia kēia hoʻokolokolo ma luna o nā kāne he 50 a ʻoi paha makahiki a ʻoi paha nā pae o ka antigen kikoʻī prostate haʻahaʻa (PSA) o 4.0 ng / ml a ʻoi iki paha. Hoʻohālikelike ʻia i ka poʻe i lawe ʻole i nā mea hoʻohui Vitamin E (Placebo a i ʻole ka hui kūmole), ua loaʻa kahi noiʻi i ka hoʻonui loa ʻana i ka makaʻu o ka maʻi ʻaʻai prostate i kēlā mau mea e lawe nei i nā huaora E. No laila, pili ka papa ʻaʻai me ka Vitamin E me ka hoʻonui ʻana o ka maʻi ʻaʻai prostate ma waena o nā kāne olakino. (Klein EA et al, JAMA, 2011)
I loko o ka alpha-tocopherol, beta-carotene ATBC noiʻi kāohi ʻana i ka maʻi ʻaʻai i hana ʻia i nā kāne puhipaka ma mua o 50 mau makahiki, ʻaʻole i loaʻa iā lākou kahi hōʻemi o ka maʻi ʻaʻa pūhae ma hope o ʻelima a ʻewalu mau makahiki o ke kākoʻo papaʻai me ka alpha-tocopherol. (New Engl J Med, 1994)
Nā pono o ka Wikamina E i ka maʻi ʻaʻai Ovarian
I ka pōʻaiapili o ka ovarian Ka maʻi 'aʻai, Ua hōʻike ka Vitamin E compound tocotrienol i nā pōmaikaʻi ke hoʻohana pū ʻia me ka maʻamau o ka lāʻau mālama mālama bevacizumab (Avastin) i nā maʻi i kū i ka lāʻau chemotherapy. Ua aʻo nā mea noiʻi ma Denmark i ka hopena o ka tocotrienol subgroup o Vitamin E i hui pū me ka bevacizumab i nā maʻi maʻi maʻi ovarian i pane ʻole i ka mālama ʻana i ka chemotherapy. ʻO ka haʻawina he 23 mau maʻi. ʻO ka hui pū ʻana o ka Vitamin E/tocotrienol me ka bevacizumab i hōʻike i ka haʻahaʻa haʻahaʻa loa i ka poʻe maʻi maʻi maʻi a loaʻa iā 70% ka maʻi stabilization rate. (Thomsen CB a me al, Pharmacol Res., 2019)
ʻO nā kumuwaiwai, nā pono a me nā pilikia o ka Vitamin K i ka maʻi ʻaʻai
kumu : ʻO ka Vitamin K kahi mea waiwai nui e pono ai no ke kāpili ʻana i ke koko a me nā iwi olakino, me nā hana ʻē aʻe i ke kino. Hiki i kona hemahema ke kumu i nā palapū a me nā pilikia kahe. ʻIke maoli ia i nā meaʻai he nui e like me nā lau lau ʻōmaʻomaʻo e like me ka milo, kale, broccoli, lettuce; i nā aila mea kanu, nā huaʻai e like me nā blueberry a me nā fiku a i loko hoʻi o ka ʻiʻo, ka tī, nā hua a me nā soybeans. I kēia manawa ʻaʻohe hōʻike hōʻoia o ka hui o Vitamin K me ka hoʻonui a hoʻemi ʻia paha o ka maʻi ʻaʻai.
Panina
Hōʻike nā ʻano noiʻi lapaʻau like ʻole āpau i ka lawe ʻia ʻana o ka wikamina a me ka nutrient i ke ʻano o nā meaʻai maoli, nā huaʻai, nā mea kanu, nā ʻiʻo, nā hua manu, nā hua waiū, nā hua, nā aila ma ke ʻano he papaʻai olakino, kaulike ka mea e pono nui ai no mākou. ʻO ka hoʻohana nui ʻana o nā multivitamins a i ʻole nā huina huamine pākahi i hōʻike ʻole ʻia e hoʻohui i ka waiwai nui i ka pale ʻana i ka hopena o ka maʻi ʻaʻai, a hiki ke loaʻa ka hopena i ka ʻeha. I ka hapanui o nā hihia, ua loaʻa nā noiʻi i kahi hui o nā kiʻina kiʻekiʻe o nā wikamina a i ʻole multivitamins me ka hoʻonui ʻana i ka maʻi ʻaʻai. Wale i kekahi mau ʻike kikoʻī e like me ke ʻano o ka hoʻopili ʻana o Vitamin C i nā maʻi maʻi ʻaʻai me GBM a i ʻole Leukemia a i ʻole hoʻohana ʻia o tocotrienol / vitamin E i nā mea maʻi maʻi ʻaʻa ovarian i hōʻike i ka hopena maikaʻi i ka hoʻomaikaʻi ʻana i nā hopena a me ka hōʻemi ʻana i nā hopena ʻaoʻao.
No laila, ke hōʻike nei nā hōʻike ʻepekema he kōkua ʻole kahi hana maʻamau a me ka lōkahi o ka nui o ka vitamina a me nā multivitamin no ka hōʻemi ʻana i ka maʻi ʻaʻai. Pono e hoʻohana i kēia mau mea hoʻohui multivitamin no ka maʻi ʻaʻai ma luna o nā ʻōlelo aʻoaʻo mai nā kauka loea i ka pōʻaiapili a me ke kūlana kūpono. No laila nā hui e like me ka Academy of Nutrition and Dietetics, ka American Cancer Society, ka American Institute of Cancer Research a me ka American Heart Association ʻaʻole e hoʻolaha i ka hoʻohana ʻana i ka papaʻai. kumukanawai a aiʻole multivitamins e pale aku i ka maʻi ʻaʻai a i ʻole nā maʻi puʻuwai.
He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.
ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.
E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.
Mea 'ai pilikino no ka ma'i 'a'ai!
Hoʻololi ka maʻi kanesa me ka manawa. Hoʻopilikino a hoʻololi i kāu meaʻai e pili ana i ka hōʻailona maʻi maʻi, ka mālama ʻana, ke ʻano o ka nohona, nā makemake meaʻai, nā allergies a me nā mea ʻē aʻe.
ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy e pili ana i ko lākou ola a nānā aku no nā hoʻoponopono ʻē aʻe no ka maʻi ʻaʻai ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.