Flavonoid Foods da Amfanin su a Ciwon daji

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Karatuttukan daban daban sun nuna cewa flavonoids suna da tarin fa'idodi na kiwon lafiya wadanda suka hada da antioxidant, anti-inflammatory da cututtukan yaƙi da ciwon daji kuma ana samun su a cikin abinci iri-iri ciki har da fruitsa fruitsan itace (kamar su cranberries, blueberries, blackberries, bilberries, apples fiber rich etc), kayan lambu da abubuwan sha. Don haka, gami da abinci mai yawan flavonoid a matsayin wani ɓangare na abincinmu na yau da kullun zai zama mai amfani. Koyaya, kafin shan duk wani kari na flavonoid, masu cutar kansa yakamata koyaushe su tattauna da kwararrun likitocin su.

Menene flavonoids?

Flavonoids rukuni ne na abubuwan da ke haifar da sinadarai masu amfani da ƙwayoyin cuta da kuma tarin abubuwa masu rai waɗanda aka samo su da yawa a cikin abinci iri daban-daban. Flavonoids sun kasance a cikin nau'ikan 'ya'yan itace, kayan lambu, kwayoyi, iri, kayan yaji, hatsi, haushi, saiwoyi, mai tushe, furanni da sauran abincin tsirrai da abubuwan sha kamar shayi da ruwan inabi. Tare da yawan amfani da flavonoids ta hanyar shan fruitsa fruitsan itace da kayan lambu masu wadataccen kayan lambu, an gudanar da bincike daban-daban a duk faɗin duniya don kimanta fa'idodin kiwon lafiyar su da abubuwan yaƙar cutar kansa.

Classes daban-daban na Flavonoids da Tushen Abinci

Dangane da tsarin sunadarai na flavonoids, ana sanya su cikin ƙananan rukuni masu zuwa.

1. Anthocyanins
2. Kalubale
3. Flavanones
4. Flavones
5. Flavonols
6. Flavan-3-ol
7. isoflavones

Anthocyanins - Flavonoid Subclass & Tushen Abinci

Anthocyanins sune launukanda ke da alhakin samar da launuka ga furanni da fruitsa fruitsan tsire-tsire. An san su da kyawawan ƙwayoyin antioxidant. Ana amfani da flavonoid Anthocyanins a masana'antar abinci saboda fa'idodin lafiya da kwanciyar hankali. 

Wasu daga misalan anthocyanins sune:

• Delphinidin
• Cyanidin 
• Pelargonidin
• Malvidin 
• Peonidin da
• Petunidin

Tushen abinci na Anthocyanin flavonoids: Ana samun Anthocyanins da yawa a cikin fatar waje ta varietya fruitsan /a fruitsan itace / berriesa beran itace da kayayyakin Berry gami da:

• Red inabi
• 'Ya'yan inabi Merlot
• Red giya
• Cranberries
• Black currants
• Rasberi
• strawberries
• blueberries
• Bilberries da 
• Bishiyar Gashi

Chalcones - vananan Flavonoid & Tushen Abinci

Chalcones wani karamin rukuni ne na flavonoids. An kuma san su da suna flavonoids mai buɗewa. Chalcones da danginsu suna da fa'idodi da yawa da kuma ƙoshin lafiya. Abun ciki da alama suna da aiki a kan ƙwayoyin cutar kansa, suna ba da shawarar cewa suna da abubuwan mallakar cutar kansa. Chalcones an san su da antioxidative, antibacterial, anti-inflammatory, anticancer, cytotoxic, da immunosuppressive Properties. 

Wasu daga cikin misalan allon sune:

• Arbutin 
• Phloridzin 
• Phloretin da 
• Chalconaringenin

Flavonoids, Chalcones, ana samun su a cikin abinci iri-iri kamar:

• Lambun tumatir
• Shalolin
• Bean ta tsiro
• Pears
• strawberries
• Bishiya
• Licorice da
• wasu kayayyakin alkama

Flavanones - Flavonoid Subclass & Tushen Abinci

Flavanones, wanda aka fi sani da dihydroflavones, wasu ƙananan ƙananan ƙananan flavonoids ne tare da ƙwayoyin antioxidant masu ƙarfi da kuma kyawawan abubuwa masu sassauƙa. Flavanones yana ba da ɗanɗano mai ɗaci ga bawo da ruwan 'ya'yan itacen citrus. Wadannan citrus flavonoids kuma suna nuna abubuwan kare kumburi kuma suna aiki azaman saukar da jini da kuma rage yawan cholesterol.

Wasu daga cikin misalan flavanones sune:

• Eriodictyol
• Hesperetin da
• Narin

Flavonoids, Flavanones, galibi ana samunsu a cikin abinci irin su duk 'ya'yan itacen citrus gami da:

• lemu
• Limes
• Lemons da
• Inabi

Flavones- The Flavonoid Subclass & Tushen Abinci

Flavones sune ƙananan ƙananan flavonoids waɗanda suke da yawa a cikin ganye, furanni da fruitsa fruitsan itace azaman glucosides. Su ne launuka masu launuka masu shuɗi da fari masu shuke-shuke. Flavones kuma yana aiki azaman magungunan ƙwari na halitta a cikin tsirrai, suna ba da kariya daga kwari da cututtukan fungal. Flavones sananne ne yana da ƙarfin antioxidant da anti-inflammatory. 

Wasu daga misalan flavones sune:

• Apigenin
• luteolin
• Baicaleen
• chrysin
• Tangeritin
• Nobilatin
• Sinensetin

Flavonoids, Flavones, galibi suna cikin abinci irin su:

• seleri
• faski
• jan barkono
• chamomile
• ruhun nana
• ginkgo biloba

Flavonols - Flavonoid Subclass & Tushen Abinci

Flavonols, wani karamin rukuni na flavonoids da tubalin ginin proanthocyanins, ana samun su a cikin 'ya'yan itatuwa da kayan marmari da yawa. Flavonols sanannu ne da fa'idodin kiwon lafiya da yawa ciki har da ƙarfin antioxidant da rage haɗarin cutar jijiyoyin jini. 

Wasu daga misalan flavonols sun haɗa da:

• Fisetin 
• Quercetin
• myricetin 
• Rutin
• Kaempferol
• Isorhamnetin

Flavonoids, Flavonols, galibi suna cikin abinci irin su:

• albasarta
• Kale
• tumatir
• apples
• inabi
• berries
• Tea
• Red giya

Flavan-3-ols - Flavonoid Subclass & Tushen Abinci

Flavan-3-ols sune manyan flavonoids na shayi tare da fa'idodi da yawa na kiwon lafiya. Flavan-3-ols an san suna da antioxidant, anti-inflammatory da anti-cancer. 

Wasu daga misalan flavan-3-ols sun haɗa da:

• Catechins da kwatancen gallate su: (+) - Catechin, (-) - Epicatechin, (-) - Epigallocatechin, (+) - Gallocatechin
• Theaflavins, Thearubigins
• Proanthocyanidins

Flavonoids, Flavan-3-ols, galibi suna cikin abinci irin su:

• baƙar shayi
• kore shayi
• Farin shayi
• oolong shayi
• apples
• kayan koko
• inabi mai ruwan hoda
• jan inabi
• Red giya
• blueberries
• strawberries

Isoflavones - Flavonoid Subclass & Tushen Abinci

Isoflavonoids wani rukuni ne na flavonoids kuma wasu daga cikin danginsu ana kiran su phytoestrogens saboda aikin estrogenic nasu. Isoflavones suna da alaƙa da kayan magani ciki har da maganin ciwon daji, maganin antioxidant, da kuma cututtukan zuciya saboda aikin hana karɓar mai karɓar estrogen.

Wasu daga misalan isoflavones sune:

• Samarin
• Daidzein
• Glycitein
• Injin A
• Formononetin

Daga cikin waɗannan, isoflavones kamar genistein da daidzein sune mafi mashahuri phytoestrogens.

Flavonoids, isoflavones, galibi suna cikin abinci irin su:

• Waken soya
• Kayan waken soya da samfuran
• Tsirrai masu ban tsoro

Wasu isoflavonoids na iya kasancewa a cikin microbes. 

Ciwon Yaƙin Cancer na Flavonoids da ke cikin 'Ya'yan itãcen marmari, Kayan lambu & abubuwan sha

Flavonoids an san su da fa'idodi da yawa na kiwon lafiya saboda abubuwan antioxidant da anti-inflammatory. Wasu daga cikin fa'idodin lafiyar abinci mai wadataccen flavonoid an jera su a ƙasa.

• Ciki har da flavonoids a cikin abincinmu na iya taimakawa wajen sarrafa hawan jini.
• Flavonoids na iya taimakawa wajen rage aukuwar bugun zuciya ko bugun jini.
• Flavonoids na iya taimakawa wajen rage haɗarin ciwon sukari.
• Wasu nazarin sunyi rahoton cewa flavonoids na iya haɓaka ƙashi kuma ya hana haɓakar ƙashi.
• Flavonoids na iya haɓaka haɓaka a cikin tsofaffi.

Tare da duk fa'idodin kiwon lafiya da aka ambata, flavonoids da ake yawan samu a cikin abinci irin su 'ya'yan itace, kayan lambu da abubuwan sha duk an san su suna da kaddarorin yaƙi da cutar kansa. Flavonoids na iya yin maganin radicals na kyauta wanda zai iya lalata macromolecules kamar DNA. Hakanan waɗannan zasu iya taimakawa cikin gyaran DNA kuma suma hana angiogenesis da mamaye ƙari.

Yanzu zamu zurfafa zuwa wasu daga cikin karatun da aka gudanar don kimanta kaddarorin yaƙi da cutar kansa na canceran flavonoids / wadataccen abinci mai flavonoid gami da fruitsa fruitsan itace, kayan marmari da abubuwan sha. Bari mu ga abin da waɗannan nazarin suka ce!

Amfani da Soy Isoflavone Genistein tare da Chemotherapy a cikin Cancer na Cancer na Yanayi

Metastatic Colorectal Cancer yana da mummunan hangen nesa tare da rayuwa na shekaru 2 ƙasa da 40% da rayuwa na shekaru 5 ƙasa da 10%, duk da haɗarin haɗakar haɗakar zaɓuɓɓukan maganin cutar shan magani (AJCC Cancer Staging Handbook, 8th Edn). Karatu daban-daban sun nuna cewa mutanen gabashin Asiya waɗanda ke cin abinci mai yalwar Soy suna da alaƙa da ƙananan haɗarin cutar kansa. Yawancin binciken gwaji na yau da kullun sun kuma nuna alamun anti-cancer na soy isoflavone Genistein, da ikonsa na rage juriya na maganin cutar kansar cikin ƙwayoyin kansa.  

Masu bincike a Icahn Makarantar Magunguna a Dutsen Sinai, a New York, sun kimanta aminci da ingancin shan isoflavone Genistein tare da daidaitattun kulawar haɗuwa da cutar shan magani a cikin binciken asibiti mai zuwa a cikin cututtukan cututtukan cututtukan cututtukan cututtukan zuciya (NCT01985763) (Pintova S et al , Ciwon daji Chemotherapy & Pharmacol., 2019). Nazarin ya hada da marasa lafiya 13 da ke fama da cutar kansa ba tare da wani magani na farko ba, tare da marasa lafiya 10 da aka yi amfani da su tare da haɗin FOLFOX chemotherapy da Genistein da kuma marasa lafiya 3 da aka yi wa magani tare da FOLFOX + Bevacizumab da Genistein. Haɗuwa da Genistein tare da waɗannan magungunan sun sami aminci da haƙurin zama.

Akwai ci gaba a cikin mafi kyawun cikakkiyar amsa (BOR) a cikin waɗannan cututtukan cututtukan cututtukan cututtukan fata da ke shan maganin tare da Genistein, idan aka kwatanta da waɗanda aka ba da rahoto game da maganin ƙwaƙwalwar a cikin karatun farko. BOR ya kasance 61.5% a cikin wannan binciken idan aka kwatanta da 38-49% a cikin binciken da ya gabata tare da maganin jiyya guda ɗaya. (Saltz LB et al, J Clin Oncol, 2008) Ko da tsarin ci gaba na rayuwa kyauta, wanda ke nuna adadin lokacin da kumburin bai ci gaba ba tare da maganin, ya kasance tsaka-tsakin watanni 11.5 tare da haɗin Genistein a cikin wannan binciken idan aka kwatanta da 8 watanni don chemotherapy kadai bisa ga binciken da aka gabata. (Saltz LB et al, J Clin Oncol., 2008)

Nazarin ya nuna cewa zai iya zama lafiya don amfani da waken soy isoflavone Genistein tare da hadewar sinadarai na FOLFOX don maganin cutar kansa. Hada Genistein tare da chemotherapy yana da damar haɓaka sakamakon magani. Koyaya, waɗannan binciken, kodayake masu ba da tabbaci ne, ana buƙatar a kimanta su a cikin manyan karatun asibiti.

Amfani da flavonol Fisetin a Ciwon Cancer na Yanayi

Flavonol - Fisetin wakili ne mai canza launi wanda a dabi'ance ana samunsa a cikin shuke-shuke da kayan lambu da yawa ciki har da strawberries, tuffa mai yalwar fiber da inabi. An san cewa yana da fa'idodi daban-daban na kiwon lafiya irin su neuroprotective, anti-inflammatory, da anti-carcinogenic effects. An gudanar da karatu daban-daban don kimanta tasirin Fisetin akan sakamakon cutar shan magani a cikin masu cutar kansa.

An gudanar da bincike na asibiti a cikin 2018 daga masu bincike daga Iran don nazarin tasirin karin fisetin akan abubuwan da suka shafi kumburi da yaduwar cutar kansa (metastasis), a cikin marasa lafiya na Canrectal Cancer masu karɓar adjuvant chemotherapy (Farsad-Naeimi A et al, Abincin Abinci. 2018). Binciken ya hada da marasa lafiya 37 masu shekaru 55 ± 15, wadanda aka shigar da su Sashin ilimin Oncology na Tabriz University of Medical Sciences, Iran, tare da mataki na biyu ko na uku kansar kansa, tare da tsawon rai na fiye da watanni 3. Oxaliplatin da capecitabine sune tsarin kula da cutar sankara. Daga cikin marasa lafiya 37, marasa lafiya 18 suma sun sami 100 mg na fisetin na makonni 7 a jere. 

Binciken ya gano cewa rukunin da ke amfani da kari na fisetin yana da raguwa mai yawa game da cutar mai saurin kamuwa da cutar ta IL-8 idan aka kwatanta da rukunin sarrafawa. Binciken ya kuma nuna cewa karin Fisetin ya kuma rage matakan wasu daga cikin sauran kumburin da abubuwan da ke haifar da cutar kamar su hs-CRP da MMP-7.

Wannan ƙaramin gwajin na asibiti yana nuna fa'idodin fisetin a cikin rage alamun cututtukan cututtukan ƙwayoyin cuta a cikin masu fama da cutar kansa lokacin da aka ba su tare da ɗan adonsu na chemotherapy.

Amfani da Flavan-3-ol Epigallocatechin-3-gallate (EGCG) a cikin Esophageal Cancer Marasa lafiya da aka bi da tare da Radiation Far

Epigallocatechin-3-gallate (EGCG) shine flavonoid / flavan-3-ol tare da ƙwayoyin antioxidant masu ƙarfi da kuma abubuwan da ke da kumburi. Hakanan ana amfani dashi don rage haɗarin takamaiman sankara da kuma sauƙaƙa wasu cututtukan cututtukan chemotherapy. Yana daya daga cikin sinadarai mafiya yawa da ake samu a koren shayi sannan kuma ana samun shi cikin farin, oolong, da baƙin shayi.

A cikin binciken asibiti na lokaci na II da Shandong Cancer Hospital da Institute in China suka gudanar, bayanai daga jimillar marasa lafiya 51 sun hada da, daga cikinsu 22 marassa lafiya sun sami maganin kimiyyar bijirowa tare (an kula da marasa lafiya 14 da docetaxel + cisplatin tare da radiotherapy da 8 tare da fluorouracil + cisplatin wanda radiotherapy ya biyo baya) kuma marasa lafiya 29 sun sami maganin fuka-fuka. An lura da marasa lafiya a mako-mako don mummunan cututtukan da ke haifar da esophagitis (ARIE). (Xiaoling Li et al, Journal of Medicinal Food, 2019).

Binciken ya gano cewa ƙarin EGCG ya rage matsalolin esophagitis / haɗiye a cikin marasa lafiya masu fama da cutar kanjamau waɗanda aka kula da su ta hanyar maganin fuka-fuka ba tare da munanan tasirin tasirin maganin raɗaɗi ba. 

Ciwon Cancer na Abubuwan Apigenin

Ana samun apigenin ta halitta a cikin nau'ikan ganye iri daban-daban, kayan lambu da 'ya'yan itatuwa da suka hada da seleri, albasa,' ya'yan inabi, inabi, apples, chamomile, spearmint, basil, oregano. Apigenin yana da kayan antioxidant tare da anti-inflammatory da antibacterial properties. Nazarin pre-asibiti daban-daban da aka yi akan nau'ikan layin ƙwayoyin cuta da nau'ikan dabbobin da ke amfani da Apigenin sun kuma nuna tasirin cutar kansa. Flavonoids kamar Apigenin suna taimakawa cikin matakan hana kamuwa da cutar don rage yiwuwar haɗarin tasowa a nan gaba amma kuma yana iya yin aiki tare tare da wasu magunguna don haɓaka ingancin magani (Yan et al, Cell Biosci., 2017).

A cikin nazarin daban-daban ta amfani da al'adun tantanin halitta da nau'in dabba, Apigenin ya inganta ingantaccen maganin chemotherapy na gemcitabine a cikin in ba haka ba da wuya a magance ciwon daji na pancreatic (Lee SH et al, Cancer Lett., 2008; Strouch MJ et al, Pancreas, 2009). A wani binciken tare da prostate ciwon daji Kwayoyin, Apigenin lokacin da aka haɗa shi da maganin chemotherapy Cisplatin ya inganta tasirin cytotoxic sosai. (Erdogan S et al, Biomed Pharmacother., 2017). Wadannan binciken sun nuna cewa Apigenin da ake samu a cikin 'ya'yan itatuwa, kayan lambu da ganye daban-daban suna da damar yin yaki da ciwon daji.

Ciwon daji na Yarjejeniyar Canji na Flavonoid da Tuffa masu arzikin fiber 

Tuffa suna da wadata a cikin antioxidants iri-iri, ciki har da flavonoids kamar su quercetin da catechin. Tuffa kuma suna da yalwar fiber, bitamin, da kuma ma'adanai, waɗanda duk suna amfanar lafiya. Abubuwan antioxidant na waɗannan kwayoyin halittar jiki da zare a cikin tuffa na iya kare DNA daga lalacewar kumburi. An gudanar da karatu daban-daban don kimanta tasirin waɗannan flavonoid / bitamin / fiber mai amfani da apple akan haɗarin cutar kansa. 

Wani bincike-bincike na binciken bincike daban-daban da aka gano ta hanyar binciken wallafe-wallafe a cikin PubMed, Yanar Gizo na Kimiyya da bayanan Ofishin Jakadancin sun gano cewa yawan amfani da flavonoid/bitamin/ fiber apple yana da alaƙa da rage haɗarin huhu. ciwon daji.(Roberto Fabiani et al, Kiwon Lafiyar Jama'a Nutr., 2016) Kadan daga cikin binciken kula da shari'o'in kuma sun sami raguwar haɗarin launin fata, nono da kuma ciwon daji na tsarin narkewa gaba ɗaya tare da ƙara yawan amfani da apples. Abubuwan anti-cancer na apples, duk da haka, ba za a iya danganta su ga flavonoids kadai ba, saboda yana iya kasancewa saboda abubuwan gina jiki kamar bitamin, ma'adanai da fibers. Fiber ɗin abinci (wanda kuma ana samun su a cikin apples) an san su don rage haɗarin ciwon daji na hanji.(Yu Ma et al, Medicine (Baltimore), 2018)

Amfanin lafiya na Flavonoid mai wadatar Cranberries

Cranberries shine kyakkyawan tushen abubuwan da ke tattare da kwayoyin halitta ciki har da flavonoids kamar anthocyanins, bitamin da antioxidants kuma suna da fa'idodin kiwon lafiya iri-iri. Ofaya daga cikin mahimman fa'idodin Cranberry na fitar da hoda shine yana rage cututtukan fitsari (UTIs). Amfanin lafiyar Proanthocyanidin da ake samu a cikin cranberries sun hada da hana ci gaban kwayoyin cuta wadanda ke haifar da daskararrun abu, kofofi da matakan farko na cututtukan danko. ciwon daji na yaki da kaddarorin.

A cikin binciken binciken makafi na wuri biyu, masu binciken sun binciki fa'idodin lafiyar cranberries ta hanyar tantance tasirin shan kifin a kan dabi'un takamaiman antigen (PSA) da sauran alamomi a cikin maza masu fama da cutar kansar mafitsara a gabanin prostatectomy.Vladimir Student et al, Biomed Pap Med Fac Univ Palacky Olomouc Jamhuriyar Czech, 2016) Binciken ya gano cewa yawan cin 'ya'yan itacen cranberry na yau da kullum yana rage sinadarin PSA ga marasa lafiya da ke fama da cutar sankarar mafitsara da kashi 22.5%. Masu binciken sun yanke shawarar cewa wannan fa'idodin kiwon lafiyar na iya yiwuwa ne saboda kaddarorin sinadarai masu amfani da sinadarai na cranberries wadanda ke tsara bayyanar kwayoyin halitta masu amsa androgen, waɗanda ke taka muhimmiyar rawa a cikin ci gaba da ci gaba da cutar kansa ta prostate.

Kammalawa

Nazarin daban-daban sun nuna cewa flavonoids suna da fa'idodin kiwon lafiya da yawa ciki har da kaddarorin yaƙi da cutar kansa kuma ana samun su a cikin abinci iri-iri ciki har da 'ya'yan itatuwa (kamar fiber mai yawa). apples, inabi, cranberries, blueberries), kayan lambu (kamar tumatur, tsire-tsire na leguminous) da abubuwan sha (kamar shayi da jan giya). Shan abinci mai arzikin flavonoid a matsayin wani bangare na abincin mu na yau da kullun zai yi amfani. Koyaya, kafin bazuwar haɗawa da kowane ƙarin abubuwan flavonoid ko maida hankali azaman ɓangare na abincin mai haƙuri, ya kamata mutum ya tattauna shi tare da kwararrun likitocin kiwon lafiya. 

Abincin da kuke ci kuma wanne kari kuke ɗauka shine yanke shawara. Ya kamata shawararku ta haɗa da la'akari da maye gurbi na ciwon daji, wanda cutar kansa, jiyya da ci gaba da gudana, duk wani rashin lafiyan, bayanin salon rayuwa, nauyi, tsayi da halaye.

Tsarin abinci mai gina jiki don cutar kansa daga addon baya dogara ne akan binciken intanet. Yana sarrafa muku yanke shawara ta atomatik dangane da kimiyyar kwayoyin da masana kimiyya da injiniyoyin software suka aiwatar. Ba tare da la’akari da ko kuna kula da fahimtar hanyoyin hanyoyin kwayoyin halittar biochemical ko a'a - don shirin abinci mai gina jiki don cutar kansa wanda ake buƙatar fahimta.

Fara NOW tare da shirin abinci mai gina jiki ta hanyar amsa tambayoyi kan sunan cutar kansa, maye gurbi, jiyya mai gudana da kari, duk wani rashin lafiyan, halaye, salon rayuwa, ƙungiyar shekaru da jinsi.

Marasa lafiya masu cutar kansa sau da yawa dole su magance daban-daban illar illa na chemotherapy wanda ke shafar ingancin rayuwarsu da kuma neman wasu hanyoyin magance cutar kansa. Shan da madaidaicin abinci mai gina jiki da kari bisa la'akari na kimiyya (gujewa zato da zabin bazuwar) shine mafi kyawun maganin halitta don cutar kansa da cututtukan da suka shafi magani.

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