Amaphuzu avelele
I-Vitamin E iyi-antioxidant etholakala ekudleni okuhlanganisa amafutha ommbila, amafutha emifino, amafutha esundu, ama-alimondi, ama-hazelnuts, amantongomane kaphayini kanye nembewu ye-sunflower. Izazi ze-oncologists zivame ukusebenzisa i-Avastin (Bevacizumab) njengokwelashwa kwe-ovarian umdlavuza. Ucwaningo oluhlukahlukene lubonise ukuthi ukudla ukudla okufanele okuhlanganisa ukudla okufanele kanye nezithako ezisizayo kungasiza ekuthuthukiseni imiphumela yokwelashwa ezigulini ezinomdlavuza. Olunye ucwaningo lomtholampilo olunjalo olwenziwa eDenmark lubonise ukuthi ukusebenzisa i-Vitamin E (tocotrienol) kanye ne-Avastin (Bevacizumab) kuphinde kabili izinga lokusinda futhi kwazinzisa lesi sifo ku-70% weziguli ezinomdlavuza we-ovarian ezimelana nokwelashwa ngamakhemikhali. Lokhu kubonisa ukuthi ukudla okunothe nge-Vitamin E kungase kube usizo ezigulini ezinomdlavuza wesibeletho, njengoba kungase kuthuthukise impendulo yokwelapha ye-Avastin/Bevacizumab. Kubalulekile ukwenza ukudla okunomsoco kuye ngohlobo oluthile lomdlavuza kanye nokwelashwa okuqhubekayo ukuze uthole izinzuzo zokudla okunomsoco kanye nokuphepha.
IVitamin E kanye Nemithombo Yayo Yokudla
I-Vitamin E yisakhi somzimba esine-antioxidant esitholakala ezinhlotsheni ezahlukahlukene zokudla kubandakanya uwoyela wommbila, uwoyela wemifino, uwoyela wesundu, ama-alimondi, ama-hazelnut, uphayini-amantongomane nembewu ye-sunflower, ngaphandle kwezinye izithelo nemifino. Itholakala futhi njengesengezo sokudla futhi yaziwa njengokuningi izinzuzo zezempilo esukela ekunakekelweni kwesikhumba kuya enhliziyweni nasemphefumulweni othuthukisiwe. Izici ze-antioxidant zika-Vitamin E zisiza ukuvikela amaseli emonakalweni odalwe ama-radicals wamahhala asebenzayo nokucindezela kwe-oxidative.
Cancer wesibeletho
Isizathu esenza umdlavuza we-ovari ubulale kakhulu abesifazane abaningi emhlabeni wonke kungenxa yokuthi izigaba zokuqala zalo mdlavuza azivami ukudala izimpawu. Phakathi nezigaba zakamuva zalo mdlavuza, izimpawu ezifana nokwehlisa isisindo nobuhlungu besisu, okungajwayelekile okungaqondile, ziqala ukubonakala futhi lokhu akuvami ukuphakamisa inhlabamkhosi enkulu. Ngenxa yalokhu, abesifazane batholakala benomdlavuza we-ovarian ngokuhamba kwesikhathi, okuholele ezingeni lokuphila elisondele eminyakeni emihlanu lama-47% (American Cancer Society).
Ukwelashwa kwe-Bevacizumab Komdlavuza we-Ovarian
Enye yezindlela zokwelashwa eziqondiswe kakhulu ezisetshenziselwa umdlavuza we-ovari yi-bevacizumab, eyaziwa nangokuthi igama lomkhiqizo elithi "Avastin". I-Bevacizumab ayisebenzi ngomqondo wendabuko we-chemo ngokuhlasela nokubulala amangqamuzana omdlavuza kepha isebenza ngokubulala izicubu ngendlala esikhundleni salokho. Esimweni sempi, lokhu kungafana nokuzungeza nokuhlukanisa idolobha ngokusika zonke izinto zabo ezibalulekile nezinsizakusebenza esikhundleni sokuhlasela ngokungenangqondo. Lokhu ikwenza ngokuvimba iprotheni eyaziwa ngokuthi yi-vascular endothelial growth factor (VEGF). Amaseli womdlavuza andise amazinga e-VEGF futhi ukuvimba le protein kusiza ukuvimbela ukukhula kwemithambo yegazi emisha ebalulekile ekuhanjisweni kwezakhamzimba kwizicubu zomdlavuza.
Ukudla Okufanele Ukudla Ngemuva Kokuxilongwa Komdlavuza!
Akukho mdlavuza owodwa ofanayo. Dlulela ngale kwemihlahlandlela ejwayelekile yokudla kuwo wonke umuntu futhi wenze izinqumo ezenziwe ngezifiso ngokudla nezithasiselo ngokuzethemba.
Vitamin E Ukwengezwa kanye neBevacizumab ngomdlavuza we-Ovarian
Nakuba ukwelashwa kwe-Bevacizumab kanye ne-chemotherapy kuvunyiwe ukwelashwa komdlavuza we-ovarian, ukukhetha ukudla okulungile okuzohambisana ne-avastin kumdlavuza we-ovarian kubalulekile. Ucwaningo lwakamuva olwenziwe abacwaningi besibhedlela saseDenmark lubonise ukusebenza kwesengezo esingasebenzisana ne-Bevacizumab futhi sithuthukise amathuba okusinda kweziguli ezinomdlavuza wesibeletho. I-Delta-tocotrienols iyiqembu elithile lamakhemikhali angatholakala kuVithamini E. Ngokuyisisekelo, uVithamini E wakhiwe amaqembu amabili amakhemikhali- tocopherols kanye ne-tocotrienols. UMnyango Wezempilo Esibhedlela saseVejle, eDenmark, uhlole umphumela weqembu elincane le-tocotrienol likavithamini E lihlanganiswe ne-bevacizumab kumdlavuza we-ovarian we-chemo refractory. Lesi bekuyisilingo sokuqala somtholampilo esenziwa kusetshenziswa le nhlanganisela ye-ovarian engazweli okuningi umdlavuza futhi imiphumela ibonakala ithembisa.
Uma kuqhathaniswa nokusinda kwamahhala kwe-Progression Free Survival kwezinyanga ezi-2 kuya kwezi-4 kanye nokusinda okumaphakathi kwezinyanga eziyi-5-7, ukwelashwa okuhlangene kwe-bevacizumab ne-delta-tocotrienol kucishe kwakuphinda kabili ukusinda, kanti iziguli zifinyelela kwi-median PFS yezinyanga eziyi-6.9 kanye ne-OS ephakathi wezinyanga eziyi-10.9, ukugcina izinga lokuqina kwezifo kuma-70% ngobuthi obuncane (I-Thomsen CB et al, i-PharmacolRes. 2019). Ukudla okunomsoco / Ukudla okunothe kuVitamin E kungahle kube lusizo (ikhambi lemvelo) leziguli ezinomdlavuza we-chemo ezingamelana ne-ovarian eziphathwe nge-Avastin ngokwenza ngcono izinga lokuphendula.
Isiphetho
Lolu cwaningo lubonise umphumela wokulwa nomdlavuza we-delta-tocotrienol kumdlavuza we-ovarian ongazweli, kodwa okufanayo akusungulwa kuma-tocopherols. Izithako eziningi ze-Vitamin E ziphezulu kuma-tocopherol kune-tocotrienols. Uma iphuzwa ngenani elifanele, i-tocotrienol ibonakala inezinye izinzuzo eziningi zezempilo kusukela ekunakekelweni kwesikhumba kuya ekuthuthukisweni kwenhliziyo nempilo yobuchopho. Ukudla okungokwemvelo kuhlala kungcono futhi kungatholakala ku-rice bran, amafutha esundu, i-rye, oats, nebhali. Ngokuphathelene nokudla i-tocotrienol supplements for umdlavuza ukwelashwa, umuntu kufanele ahlale exoxa okufanayo nodokotela wabo ngaphambi kokuyisebenzisa ngoba kuhlale kungcono ukuphepha kunokuzisola.
Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.
Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.
Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.
Ukudla Okungokwakho Komdlavuza!
Umdlavuza uyashintsha ngokuhamba kwesikhathi. Enza ngendlela oyifisayo futhi uguqule umsoco wakho ngokusekelwe kunkomba yomdlavuza, ukwelashwa, indlela yokuphila, okuncamelayo kokudla, izinto ezingakuphathi kahle nezinye izici.
Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.