Amaphuzu avelele
I-Curcumin evela ku-spice Turmeric ithuthukise ukusabela kwe-FOLFOX chemotherapy ezigulini ezinomdlavuza we-colorectal njengoba kuqokonyiswe ukuhlolwa komtholampilo kwesigaba II. Ukusinda sekukonke ezigulini ezithatha i-FOLFOX ngokuhlanganiswa nezithako ze-Curcumin kwakuphindwe kabili uma kuqhathaniswa neqembu elithatha kuphela i-FOLFOX: ikhambi lemvelo elingaba khona lomdlavuza we-colorectal. Kuhlanganisa Curcumin njengengxenye ye-colorectal Ukudla kweziguli ezinomdlavuza ngenkathi ukwelashwa kwe-FOLFOX kungasiza.
Izithako zemvelo zomdlavuza ocacile
Njengoba sikhula, umthelela oqoqayo wakho konke ukukhetha kwethu empilweni kubandakanya ukudla, ukuzivocavoca umzimba, indlela esiphila ngayo, ukuthi sikusingatha kanjani ukucindezeleka, izindlela zokulala, nokunye okuningi, kuthintana nokwakheka kofuzo lwethu futhi siphonsa inqwaba yezinselelo ezihlobene nempilo esizidingayo ukubhekana. Esinye isimo esinjalo esivela kakhulu kubantu abadala asebekhulile abaneminyaka engaphezu kwengu-50 ubudala ngumdlavuza obala, othinta amathumbu / amathumbu amakhulu. Isihlava sokuxilongwa ngumdlavuza yisigameko esiqeda impilo futhi umuntu uzama ukwenza konke okusemandleni embusweni wabo ukwenza ngcono amathuba abo okusinda. Enye yalezi zinto ezenziwa yiziguli ukushintsha ekudleni kwazo kudle ukudla okunempilo, okwemvelo nokwezitshalo (njengekhambi lemvelo lomdlavuza kubandakanya umdlavuza we-colorectal); futhi ukuthatha izithako zemvelo ezingahleliwe kutholakale ukuthi banezindawo ezilwa nomdlavuza ngokuseshwa kwabo noma ukuhanjiswa emndenini, kubangani noma kwezinye iziguli. Kodwa-ke, lokhu kusetshenziswa okungahleliwe kwezithako zemvelo ngaphandle kokwazi ukuthi kuhlangana kanjani nokwelashwa kwabo okuqhubekayo komdlavuza kuhlobo oluthile lomdlavuza kungasiza noma kulimaze imbangela yabo, ngakho-ke kufanele kwenziwe ngokunakekela nangokubonisana nochwepheshe babo bezokunakekelwa kwempilo.
Izimpawu zakuqala zomdlavuza we-colorectal zihlanganisa izimpawu ezivamile ngezinye izikhathi zokungahambi kahle kwamathumbu okungenzeka ukuthi ngokuvamile azinakwa. Ukuba khona kwama-polyps kukholoni noma igazi esitulweni nakho kuyizimpawu zalokhu umdlavuza. Ama-polyp amaningi kukholoni uma etholwa kungenzeka awanawo umdlavuza, kodwa amanye angase abonakale eyingozi. Uma itholwe futhi ilashwa kusenesikhathi ngenkathi isimila sitholakala endaweni, sinesimo esihle kakhulu sokubikezela kanye nezinga lokusinda leminyaka engu-5 lama-90% kodwa uma kutholakala lapho isimila sesisakazekele kuma-lymph nodes nezinye izitho (i-metastatic), izinga lokusinda lingaba kakhulu. zihluka phakathi kuka-14-71% (Amaqiniso Esibalo Somdlavuza Wokubona: I-Colorectal Cancer, i-NCI, i-2019).
Ukudla Okufanele Ukudla Ngemuva Kokuxilongwa Komdlavuza!
Akukho mdlavuza owodwa ofanayo. Dlulela ngale kwemihlahlandlela ejwayelekile yokudla kuwo wonke umuntu futhi wenze izinqumo ezenziwe ngezifiso ngokudla nezithasiselo ngokuzethemba.
Ngabe iCurcumin ingayithuthukisa impendulo ye-FOLFOX Chemotherapy kuColorectal Cancer?
ICurcumin, umkhiqizo wemvelo okhishwe ku-spice Turmeric osetshenziswa kakhulu uphenywe kakhulu ngawo Izici ze-anticancer. Ucwaningo lwakamuva lomtholampilo lwesigaba IIa esivulwe ngolaka esivivinywa esilawulwa ngokungahleliwe esenziwe ezigulini ezinomdlavuza we-metastatic colorectal (NCT01490996) siqhathanisa ukusinda okuphelele kweziguli ezithola i-chemotherapy yenhlanganisela ebizwa nge-FOLFOX (folinic acid / 5-FU / OXA) neqembu elitholayo I-FOLFOX kanye nama-gramu ama-2 wezithako zomlomo ze-curcumin / usuku (i-CUFOX). Ukungezwa kweCurcumin kuya ku-FOLFOX kutholakale kuphephile futhi kubekezeleleka kwiziguli ezinomdlavuza ongaconsi phansi futhi akuzange kubhebhethekise imiphumela emibi ye-chemotherapy. Ngokuya ngamazinga okuphendula, iqembu le-CUFOX libe nomphumela wokusinda ongcono kakhulu ngokusinda kwamahhala okuqhubekayo okuyizinsuku eziyi-120 ubude kuneqembu le-FOLFOX futhi ukusinda okuphelele kuphindwe kabili ku-CUFOX ngezinsuku ezingama-502 (ngaphezu konyaka nohhafu) kuqhathaniswa nama-200 kuphela izinsuku (ngaphansi konyaka) eqenjini le-FOLFOX (UHowells LM et al, J Nutriti, 2019).
Isiphetho
Kafushane, izithako ze-Curcumin noma ukudla/umsoco okucebile ku-Curcumin kungathuthukisa impendulo ye-FOLFOX chemotherapy ezigulini ezinomdlavuza we-colorectal. Izifundo ezinjalo naphezu kwamasayizi amasampula amancane, ziwusizo kakhulu futhi ziyakhuthaza ekusekeleni ukusetshenziswa kwemikhiqizo ethile yemvelo ngemithi ethile yokwelapha ngamakhemikhali. Izidakamizwa ze-FOLFOX chemotherapy zisebenza ngokudala ukulimala kwe-DNA umdlavuza amaseli futhi edala ukufa kwamaseli. Amangqamuzana omdlavuza asebenzisa izindlela zokuphunyuka ezihlukene ukuze agweme i-chemo ukuze ingabhubhi. I-Curcumin ngezenzo zayo eziningi kanye nemigomo ingasiza ekunciphiseni izindlela zokumelana ne-FOLFOX, ngaleyo ndlela ithuthukise izinga lokuphendula kanye nezingqinamba zokusinda kwesiguli somdlavuza, ngaphandle kokwengeza umthwalo wobuthi. Kodwa-ke, ukuthatha i-Curcumin noma yimuphi omunye umkhiqizo wemvelo kanye ne-chemo kufanele kwenziwe kuphela ngokusekelwe ekusekelweni kwesayensi kanye nobufakazi ngokubonisana nodokotela.
Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.
Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.
Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.
Ukudla Okungokwakho Komdlavuza!
Umdlavuza uyashintsha ngokuhamba kwesikhathi. Enza ngendlela oyifisayo futhi uguqule umsoco wakho ngokusekelwe kunkomba yomdlavuza, ukwelashwa, indlela yokuphila, okuncamelayo kokudla, izinto ezingakuphathi kahle nezinye izici.
Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.