Amaphuzu avelele
Ucwaningo oluthile oluncane lwemitholampilo luthole ukuthi i-Coenzyme Q10 / CoQ10 / ubiquinol supplementation ingaba nezinzuzo ezinhlobonhlobo ezinhlobonhlobo zomdlavuza ezifana nomdlavuza webele, i-leukemia, i-lymphoma, i-melanoma nomdlavuza wesibindi ngokunciphisa amazinga wezimpawu zokuvuvukala ze-cytokine egazini, ukuthuthukisa ikhwalithi impilo, ukunciphisa imiphumela engemihle yokwelashwa njenge-cardiotoxicity, ukunciphisa ukuphindaphinda noma ukwenza ngcono ukusinda. Ngakho-ke, ukuthatha ukudla okunothile kweCoenzyme Q10 / CoQ10 kungahle kube lusizo kulezi ziguli ezinomdlavuza. Imiphumela idinga ukuqinisekiswa ezifundweni ezinkulu.
Yini iCoenzyme Q10 / Co-Q10?
ICoenzyme Q10 (Co-Q10) iyikhemikhali elenziwe ngokwemvelo ngumzimba wethu futhi liyadingeka ekukhuleni nasekulondolozeni. Inezinto ezinamandla zokulwa ne-antioxidant futhi isiza nokunikeza amandla kumaseli. Ifomu elisebenzayo le-Co-Q10 libizwa ngokuthi yi-ubiquinol. Ngokukhula, ukukhiqizwa kwe-Co-Q10 emzimbeni wethu kuyehla. Ingozi yezifo eziningi, ikakhulukazi ngenkathi yokuguga nayo itholakele ukuthi ihlotshaniswa nokwehla kwamazinga weCoenzyme Q10 (Co-Q10).
Imithombo yokudla yeCoenzyme Q10 / Coq10
ICoenzyme Q10 noma iCoQ10 nayo ingatholwa kokudla okufana nalokhu:
- Izinhlanzi ezinamafutha ezinjenge-salmon ne-mackerel
- Inyama enjengeyenkomo nengulube
- Imifino efana ne-broccoli ne-cauliflower
- Amantongomane afana namantongomane nama-pistachio
- Imbewu yeSesame
- Inyama yomzimba efana nesibindi senkukhu, inhliziyo yenkukhu, isibindi senkomo njll.
- Izithelo ezinjengama-strawberry
- AmaSoybe
Ngaphandle kwemithombo yokudla yemvelo, iCoenzyme-Q10 / CoQ10 iyatholakala njengezithasiselo zokudla ngendlela yamaphilisi, amaphilisi angahlaziyeki, ama-syrups ketshezi, amafers kanye nemijovo efakwa emithanjeni.
Izinzuzo Ezijwayelekile Zezempilo zeCoenzyme Q10 / Co-Q10 / Ubiquinol
ICoenzyme Q10 (CoQ10) yaziwa njengezinzuzo ezahlukahlukene zezempiloKulandela ezinye zezinzuzo ezijwayelekile zezempilo zeCoenzyme Q10 (Co-Q10):
- Kungasiza ukunciphisa ingozi yezifo zenhliziyo
- Kungasiza ukunciphisa i-migraine
- Kungaba kuhle ebuchosheni futhi kusize ekunciphiseni izimpawu ze-Alzheimer's kanye neParkinson's Diseases
- Kungasiza ekwelapheni ukungazali
- Kungasiza ukunciphisa i-cholesterol
- Kungasiza ekuthuthukiseni ukusebenza komzimba kwabanye abantu abane-muscular dystrophy (iqembu lezifo elibangela ubuthakathaka obuqhubekayo nokulahleka kwemisipha).
- Kungasiza ukuvimbela isifo sikashukela
- Kungashukumisa amasosha omzimba
- Kwangathi ingavikela inhliziyo ekulimaleni okubangelwe yimithi ethile yokwelashwa ngamakhemikhali
Olunye ucwaningo lubonisa nokuthi amazinga aphezulu e-Coenzyme Q10 angase anikeze izinzuzo ezihlobene nokunciphisa ingozi yezifo ezithile kuhlanganise nezinye umdlavuza izinhlobo.
Ukudla Okufanele Ukudla Ngemuva Kokuxilongwa Komdlavuza!
Akukho mdlavuza owodwa ofanayo. Dlulela ngale kwemihlahlandlela ejwayelekile yokudla kuwo wonke umuntu futhi wenze izinqumo ezenziwe ngezifiso ngokudla nezithasiselo ngokuzethemba.
Imiphumela emibi yeCoenzyme Q10 / Ubiquinol
Ukuthatha ukudla okunothile kweCoenzyme Q10 / CoQ10 ngokuvamile kuphephile futhi kuyabekezeleleka. Kodwa-ke, ukusetshenziswa ngokweqile kweCoenzyme Q10 kungadala imiphumela emibi kubandakanya:
- I-nausea
- isiyezi
- Uhudo
- isilungulela
- Ubuhlungu besisu
- Ukulala
- Ukulahlekelwa kwesifiso
Abanye abantu baphinde babika eminye imiphumela emibi yeCoenzyme Q10 efana nokuqubuka kwesikhumba komzimba.
ICoenzyme Q10 / Ubiquinol neCancer
I-Coenzyme Q10 izuze isasasa elithile emphakathini wesayensi njengoba abantu abadala kanye nabantu abanezimo zezokwelapha ngokuvamile babenamazinga aphansi e-CoQ10. Kusukela umdlavuza yayidlange kakhulu kubantu asebekhulile futhi ingozi yomdlavuza yanda ngokuya ngeminyaka, kwaholela ezifundweni ezehlukene zokuhlola ukuthi imiphi imiphumela le enzyme engaba nayo ngempela emzimbeni. Ngezansi kunezibonelo zocwaningo olwenziwe ukuhlola ukuhlangana phakathi kweCoenzyme Q10 nomdlavuza. Ake sibheke lezi zifundo ngokushesha futhi sithole ukuthi ukudla okucebile kwe-Coenzyme Q10/CoQ10 kungase kuzuze iziguli ezinomdlavuza noma cha.
Ukusetshenziswa kwe-Co-Q10 / Ubiquinol ezigulini zomdlavuza webele
Ukusetshenziswa kwe-Co-Q10 / Ubiquinol kungahle kube nezinzuzo Zokunciphisa Izimpawu Zokuvuvukala Ezigulini Zomdlavuza Webele
Ku-2019, kwenziwa ucwaningo ngabaphenyi abavela e-Ahvaz Jundishapur University of Medical Sciences e-Iran ukuhlola imiphumela / izinzuzo ezingaba khona i-Co-enzyme Q10 (CoQ10) / ubiquinol supplementation engaba nayo ezigulini zomdlavuza webele. Ukuvuvukala Okungapheli kuyaziwa ngokwandisa ukukhula kwesimila. Ngakho-ke, baqale bahlola umthelela / inzuzo ye-CoQ10 / ubiquinol supplementation kuzimpawu ezithile zokuvuvukala ezinjenge-cytokines Interleukin-6 (IL6), Interleukin-8 (IL8) kanye ne-vascular endothelial growth factor (VEGF) egazini leziguli ezingama-30 zomdlavuza webele. ukuthola ukwelashwa kwe-tamoxifen kanye nezifundo ezinempilo ezingama-29. Iqembu ngalinye lahlukaniswa kabili neqoqo elilodwa leziguli ezinomdlavuza webele nezifundo ezinempilo ezithola i-placebo kanti elinye isethi lithola i-100 mg CoQ10 kanye ngosuku izinyanga ezimbili.
Ucwaningo luthole ukuthi i-CoQ10 supplementation inciphise amazinga e-IL-8 ne-IL-6 serum kodwa hhayi amazinga e-VEGF uma kuqhathaniswa ne-placebo. (UZahrooni N et al, Therg Risk Manag., 2019) Ngokuya ngemiphumela yaleli cohort elincane kakhulu leziguli, ukwesekwa kweCoQ10 kungasebenza ekwehliseni amazinga okuvuvukala e-cytokine, ngaleyo ndlela kunciphise imiphumela yokuvuvukala okubangelwa iziguli zomdlavuza webele. .
Ukusetshenziswa kwe-Co-Q10 / Ubiquinol kungaba nezinzuzo zokwenza ngcono ikhwalithi yempilo yeziguli ezinomdlavuza webele
Kuleli qembu elifanayo leziguli ezinomdlavuza webele ezingama-30 ezineminyaka engu-19-49 ezazisemtholampilo weTamoxifen, zahlukana phakathi kwamaqembu ama-2, elilodwa lithatha u-100 mg / usuku lwe-CoQ10 izinyanga ezimbili nelinye iqembu eliku-placebo, abacwaningi bahlola umthelela wekhwalithi impilo (QoL) yeziguli ezinomdlavuza webele. Ngemuva kokuhlaziya imininingwane, abacwaningi baphetha ngokuthi ukwengezwa kweCoQ10 kube nomthelela omkhulu ezimeni zomzimba, zenhlalo nezengqondo zabesifazane abanomdlavuza webele. (UHosseini SA et al, iPsychol Res Behav Manag., 2020 ).
Ukusetshenziswa kwe-Co-Q10 / Ubiquinol kungaba nezinzuzo zokuThuthukisa ukusinda ezigulini ezinomdlavuza wokugcina
Ucwaningo olwenziwe nguN Hertz no RE Lister baseDenmark luhlolisise ukusinda kweziguli ezingama-41 ezinomdlavuza wokugcina othole izithasiselo ze-coenzyme Q (10) kanye nengxube yamanye ama-antioxidants afana no-vitamin C, selenium, folic acid kanye ne-beta-carotene . Umdlavuza oyinhloko walezi ziguli wawutholakala ebeleni, ebuchosheni, emaphashini, ezinsweni, amanyikwe, imiphimbo, isisu, ikholoni, i-prostate, amaqanda kanye nesikhumba. Ucwaningo luthole ukuthi ukusinda kwangempela okuphakathi kwakungaphezu kuka-40% ubude kunokuphila okucatshangwe kwangaphambili. (UN Hertz no-RE Lister, J Int Med Res., Nov-Dec)
Abaphenyi baphetha ngokuthi ukuphathwa kweCoenzyme Q10 namanye ama-antioxidants kungaba nezinzuzo ezingaba khona zokwenza ngcono ukusinda kweziguli ezinomdlavuza wesigaba sokuphela futhi baphakamisa izivivinyo ezinkulu zemitholampilo zokuqinisekisa lezi zinzuzo.
ICoenzyme Q10 / Ubiquinol ingaba nezinzuzo zokunciphisa imiphumela ye-Cardiotoxicity eyenzelwe i-Cardiotoxicity Side ezinganeni ezine-Leukemia neLymphoma
Ucwaningo olwenziwe ngabaphenyi be-Medical-Surgery Institute of Cardiology, i-2nd University yaseNaples e-Italy luhlolisise umthelela wokwelashwa kwe-Coenzyme Q10 ku-cardiotoxicity ezinganeni ezingama-20 ezine-Acute Lymphoblastic Leukemia noma i-Non-Hodgkin Lymphoma ephethwe nge-Anthracyclines. Ucwaningo luthole umphumela wokuvikela weCoenzyme Q10 ekusebenzeni kwenhliziyo ngesikhathi sokwelapha i-ANT kulezi ziguli. (D Iarussi et al, iMol Aspects Med., 1994)
Ukusebenzisa i-Recombinant interferon alpha-2b ne-coenzyme Q10 njenge-posturgical adjuvant therapy ye-melanoma kunganciphisa ukuphindaphinda
Ucwaningo olwenziwe abacwaningi abavela e-Catholic University of the Sacred Heart, e-Rome, e-Italy bahlole umphumela wokwelashwa kweminyaka engu-3 nge-dose ephansi ye-interferon alpha-2b kanye ne-coenzyme Q10 ekuphindaphindeni ngemva kweminyaka engu-5 ezigulini ezinesiteji I no-II. i-melanoma (uhlobo lwesikhumba umdlavuza) kanye nezilonda ezikhishwe ngokuhlinzwa. (Luigi Rusciani et al, Melanoma Res., 2007)
Ucwaningo luthole ukuthi ukusetshenziswa kwesikhathi eside komthamo owenziwe kahle we-interferon alpha-2b kanye ne-coenzyme Q10 kwehle kakhulu amazinga wokuphindeka futhi kwaba nemiphumela emibi kakhulu.
Amaleveli aphansi weSerum weCoenzyme Q10 angahle ahlotshaniswe Nokuhlinzwa Okumaketha Okuphezulu Kokuhlinzwa ku-Cancer Cancer
Ocwaningweni olwenziwe ngabaphenyi baseTaichung Veterans General Hospital naseChung Shan Medical University, eTaichung eTaiwan, bahlole ubudlelwane phakathi kwamazinga e-coenzyme Q10 nokuvuvukala kweziguli ezine-hepatocellular carcinoma (umdlavuza wesibindi) ngemuva kokuhlinzwa. Ucwaningo luthole ukuthi iziguli ezinomdlavuza wesibindi zinamazinga aphansi kakhulu e-coenzyme Q10 namazinga aphezulu kakhulu okuvuvukala ngemuva kokuhlinzwa. Ngakho-ke, abacwaningi baphetha ngokuthi i-coenzyme Q10 ingahle ibhekwe njengokwelashwa kwe-antioxidant kweziguli ezinomdlavuza wesibindi ezinokuhlinzwa okuphezulu kokuhlinzwa okuthe xaxa. (UHsiao-Tien Liu et al, Izakhi., 2017)
Izinga eliphansi leCoenzyme Q10 lingahle Lenyuse Ubungozi BamaCancer Akhethekile
Ucwaningo olwenziwe ngabaphenyi baseYuzuncu Yil University, eVan eTurkey luthole ukuthi iziguli ezinomdlavuza wamaphaphu zinamazinga aphansi kakhulu eCoenzyme Q10. (Ufuk Cobanoglu et al, I-Asian Pac J Cancer Prev., 2011)
Olunye ucwaningo olwenziwe ngabaphenyi abavela eNyuvesi yaseHawaii eManoa luhlolisise ukuhlangana kwamazinga e-plasma CoQ10 nengozi yomdlavuza webele, ocwaningweni lokulawulwa kwamacala kwabesifazane baseChina ngaphakathi kweShanghai Women's Health Study (SWHS), bathola ukuthi labo abane amazinga aphansi we-CoQ10 ahlotshaniswa nengozi eyengeziwe yomdlavuza webele. (URobert V Cooney et al, Cancer Epidemiol Biomarkers Prev., 2011)
Isiphetho
Ikhwalithi yomthelela wempilo iyindawo ebalulekile yocwaningo ngoba ithinta cishe zonke izici zempilo yeziguli. Abaningi abasinde emdlavuza banezinga eliphansi lempilo futhi babhekene nezinkinga zokukhathala, ukucindezeleka, imigraines, izimo ezivuthayo njll. Ukuthatha ukudla okucebile kwe-Coenzyme Q10/CoQ10/ubiquinol kungase kuzuze ngokuvuselela i-oxidative metabolism yesiguli ngaleyo ndlela kunikeze isiguli amandla engeziwe ngesikhathi. izinga lamaselula. Izivivinyo ezincane ezihlukene zemitholampilo zihlole umthelela we-Coenzyme Q10/CoQ10/ubiquinol ezigulini ezinezinhlobo ezahlukene ze zomdlavuza. Bathole ukuthi i-CoQ10/ubiquinol supplementation inezinzuzo ezingaba khona ezinhlotsheni ezihlukene zomdlavuza njengomdlavuza webele, i-leukemia, i-lymphoma, i-melanoma nomdlavuza wesibindi. I-CoQ10 ibonise imiphumela emihle (izinzuzo) ngokunciphisa amazinga ezimpawu ze-cytokine ezivuthayo egazini kanye nokuthuthukisa izinga lokuphila ezigulini ezinomdlavuza webele, ukunciphisa imiphumela emibi yokwelashwa efana ne-anthracycline-induced cardiotoxicity ezinganeni ezine-leukemia ne-lymphoma, ukunciphisa ukuphindaphinda iziguli ze-melanoma noma ukuthuthukisa ukusinda ezigulini ezinomdlavuza wesigaba sokuphela. Kodwa-ke, izivivinyo zomtholampilo ezinkulu kakhulu ziyadingeka ukwenza isiphetho sangempela ekusebenzeni/izinzuzo ze-Coenzyme Q10/CoQ10/ubiquinol.
Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.
Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.
Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.
Ukudla Okungokwakho Komdlavuza!
Umdlavuza uyashintsha ngokuhamba kwesikhathi. Enza ngendlela oyifisayo futhi uguqule umsoco wakho ngokusekelwe kunkomba yomdlavuza, ukwelashwa, indlela yokuphila, okuncamelayo kokudla, izinto ezingakuphathi kahle nezinye izici.
Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.