Ukungeniswa kweMaminerali kunye neengozi zomhlaza

Iimbalasane

Uphononongo olwahlukeneyo lucebisa ukuba ukuthathwa okuphezulu kweeminerali zezondlo ezifana neCalcium, iPhosphorus kunye neCopper; kunye namanqanaba anqongopheleyo eeminerali anje ngeMagnesium, iZinc kunye neSelenium, anxulunyaniswa nomngcipheko wokwanda komhlaza. Kufuneka sithathe ukutya/isondlo esiphakamileyo kwiZinc, iMagnesium kunye neSelenium ngokwemiyinge elungileyo kwaye sinciphise ukuthathwa kweminerali yezondlo ezifana neCalcium, Phosphorus kunye neCopper ukuya kwizixa ezicetyiswayo zokunciphisa umngcipheko umhlaza. Ngelixa ukhetha izongezo, umntu akufanele abhide i-magnesium stearate yezongezelelo ze-magnesium. Ukutya okunempilo okunokulinganisela kokutya kwendalo yindlela efanelekileyo yokugcina amanqanaba acetyiswayo ezondlo zeminerali ebalulekileyo emzimbeni wethu kunye nokunciphisa ingozi yezifo ezibandakanya umhlaza. 

Zininzi izimbiwa esizityayo kunye nokutya kunye nesondlo esibalulekile kwimisebenzi yethu esisiseko yomzimba. Kukho izimbiwa eziyinxalenye yeemfuno ezinkulu ezifana neCalcium (Ca), iMagnesium (Mg), iSodium (Na), iPotassium (K), iPhosphorus (P), ezifunekayo ngokwexabiso elikhulu kwimpilo yethu. Kukho izimbiwa ezifumaneka kukutya / kwisondlo ezifunekayo kulandelwa izixa njengenxalenye yemfuno encinci kwaye zibandakanya izinto ezinje ngeZinc (Zn), Iron (Fe), Selenium (Se), Iodine (I), Copper (Cu), Manganese (Mn), iChromium (Cr) kunye nezinye. Uninzi lwezondlo zethu zezimbiwa lufunyanwa ngokutya ukutya okusempilweni nokunesondlo. Nangona kunjalo, ngenxa yezizathu ezahlukeneyo zokuphila ngendlela esempilweni kunye nokutya, intlupheko kunye nokunqongophala kokufikelela, kukho ukungalingani okuxhaphakileyo ekufumanekeni kwezi zimbiwa zibalulekileyo kunye nokusilela okanye ukugqitha okunokuthi kube nefuthe elibi kwimpilo yethu. Ngaphandle kwemisebenzi ephambili yezi zimbiwa kwimisebenzi eyahlukeneyo yomzimba, siza kuvavanya ngokuthe ngqo uncwadi ngefuthe lamanqanaba agqithisileyo okanye asweleyo ezinye zeeminerali eziphambili ngokunxulumene nomngcipheko womhlaza.

Isondlo samaminerali - iCalcium (Ca):

I-calcium, enye yezona zimbiwa ezininzi emzimbeni, ibalulekile ekwakheni amathambo omeleleyo, amazinyo kunye nokusebenza kwemisipha. Inani lokulandela umkhondo leCalcium liyafuneka nakweminye imisebenzi enje ngokuchasene nemithambo yegazi, ukuhanjiswa kwemithambo-luvo, ukutyikitywa kwe-intracellular signaling kunye ne-hormone secretion.  

Isibonelelo esinconywayo semihla ngemihla seCalcium siyahluka kubudala kodwa sikuluhlu lwe-1000-1200 mg kubantu abadala abaphakathi kweminyaka eli-19 ukuya kwengama-70.  

Imithombo yokutya eneCalcium:  Ukutya kobisi kubandakanya ubisi, itshizi, iyogathi yimithombo yendalo etyebileyo yeCalcium. Ukutya okusekwe kwizityalo ezityebile kwiCalcium kubandakanya imifuno enje ngeklabishi yaseTshayina, i-kale, i-broccoli. Isipinatshi siqulathe iCalcium kodwa ukungafumaneki kwayo kubi.

Ukutya kweCalcium kunye nomngcipheko womhlaza:  Izifundo ezininzi zangaphambili zifumanise ukuba ukutya okuphezulu kwe-calcium yamaminerali ekutyeni (kwimithombo yobisi ephantsi) okanye izongezo zinxulunyaniswa nokwehla komngcipheko womhlaza wekolon. (Slattery M et al, Am J Epidemiology, 1999; Kampman E et al, Umhlaza ubangela ulawulo, 2000; Biasco G kunye noPaganelli M, Ann NY Acad Sci, 1999) Kwisifundo seCalcium Polyp Prevention, ukongezwa kweCalcium carbonate kukhokelele ekunciphiseni ekuphuhliseni i-pre-cancerous, non-malignant, adenoma tumors kwi-colon (eyandulela umhlaza wekolon). (UGrau MV okqhubekayo, J Natl Cancer Inst., 2007)

Nangona kunjalo, uphononongo lwamva nje olwenziwe kwizigulana ezinomhlaza we-1169 ezisandula ukufunyanwa (inqanaba I-III) alibonisanga mbutho ukhuselayo okanye izibonelelo zokutya kweCalcium kunye nayo yonke into ebangela ukufa. (Wesselink E et al, Am J weKlinikhi yeSondlo, i-2020) Zininzi izifundo ezinje ezifumene imibutho engafakwanga yokutya kweCalcium kunye nokwehla komngcipheko womhlaza. Kungoko kungekho bungqina baneleyo bokuncoma ukusetyenziswa kwesiqhelo kweCalcium supplements ukuthintela umhlaza ongalunganga.  

Kwelinye icala, olunye uphononongo lwakutsha nje oludibene ne-National Health and Nutrition Examination Survey (NHANES) yedatha ukusuka ngo-1999 ukuya ku-2010 kwiqela elikhulu kakhulu labantu abadala abangama-30,899 base-US, iminyaka engama-20 okanye ngaphezulu, lafumanisa ukuba ukungeniswa kakhulu kweCalcium kunxulunyaniswa nokwanda ukubulawa ngumhlaza. Umanyano lokufa komhlaza kubonakala ngathi kunxulumene nokutya okungaphezulu kweCalcium engaphezulu kwe-1000 mg / ngosuku ngokuchasene nokungezelelwa. (UChen F okqhubekayo, iiAnnals zeInt Int., 2019)

Kukho izifundo ezininzi ezifumanise ubudlelwane phakathi kokutya okuphezulu kweCalcium enkulu kune-1500 mg / ngosuku kunye nomngcipheko okhulayo wokuba nomhlaza webala. (UChan JM okqhubekayo, Am J weKlinikhi yeNutr., 2001; URodriguez C et al, Cancer Epidemiol Biomarkers Prev., 2003; Mitrou PN okqhubekayo, Int J Cancer, 2007)

Ukuthatha okubalulekileyo:  Sidinga ukuba sibe nokutya okwaneleyo kweCalcium kwimpilo yethu yethambo kunye nezihlunu, kodwa ukongezwa okugqithileyo kweCalcium engaphaya kwesibonelelo esicetyiswayo semihla ngemihla se-1000-1200 mg / ngemini akunakuba luncedo, kwaye kunokuba nomanyano olubi kunye nokufa kwabantu abanomdlavuza. Ikhalsiyam evela kwimithombo yokutya yendalo njengenxalenye yokutya okusempilweni kuyacetyiswa ngaphezulu kokusebenzisa idosi ephezulu yokuncedisa iCalcium ukuya.

Isondlo samaminerali - iMagnesium (Mg):

I-Magnesium, ngaphandle kwendima yayo ekusebenzeni kwethambo kunye nemisipha, yeyona nto iphambili ekwenziweni kwenani elikhulu lee-enzyme ezichaphazelekayo kwiimpawu ezahlukeneyo zebhayoloji emzimbeni. I-Magnesium iyafuneka kwimetabolism, imveliso yamandla, ukudityaniswa kwe-DNA, i-RNA, iiproteni kunye ne-antioxidants, ukusebenza kwemisipha kunye ne-nerve, ulawulo lweglucose yegazi kunye nommiselo woxinzelelo lwegazi.

Isibonelelo semihla ngemihla esinconywayo seMagnesium siyahluka kubudala kodwa sikuluhlu lwe-400-420 mg yamadoda amadala, kwaye malunga ne-310-320 mg yabantu abadala ababhinqileyo, abaphakathi kweminyaka eyi-19 ukuya kuma-51 yeminyaka. 

Imithombo yokutya ene-Magnesium: Faka imifuno enamagqabi aluhlaza njengesipinatshi, imidumba, amandongomane, iimbewu kunye neenkozo ezipheleleyo, kunye nokutya okuqukethe ifayibha yokutya. Iintlanzi, iimveliso zobisi kunye nenyama engenamafutha nayo iyimithombo elungileyo yeMagnesium.

Ukutya kweMagnesium kunye nomngcipheko womhlazaUmbutho wokutya okutyayo kunye nomngcipheko womhlaza obala ngokungathandabuzekiyo uye wavavanywa kwizifundo ezininzi ezinokubakho kodwa kufunyaniswe okungahambelaniyo. Uhlalutyo lwe-meta lokuphononongwa kwe-7 yeqela lamaqela kuqhutywa kwaye kwafunyanwa umbutho obalulekileyo wokunciphisa umngcipheko womhlaza wecolorectal kunye nokutya kwamaminerali eMagnesium kuluhlu lwe-200-270mg / ngosuku. (Qu X okqhubekayo, Eur J Gastroenterol Hepatol, 2013; Chen GC okqhubekayo, Eur J Clin Nutr., 2012) Olunye uphononongo lwamva nje lufumanise ukwehla kwabo bonke oonobangela bokufa kwabantu kwizigulana ezinomhlaza onomdla wokutya okuphezulu kweMagnesium kunye amanqanaba aneleyo eVitamin D3 xa kuthelekiswa nezigulana ezazineVitamin D3 ezazinesiphene kwaye zinokutya okuncinci kweMagnesium. (UWesselink E, u-Am J weKlinikhi yeNutr., 2020) Olunye uphononongo olwalujongana nolwalamano olunokubakho lwe-serum kunye ne-Magnesium yokutya enezehlo ezinomdlavuza, zafumana umngcipheko ophezulu womhlaza we-cololoal kunye ne-serum engezantsi Magnesium phakathi kwabasetyhini, kodwa hayi abesilisa. (IPolter EJ okqhubekayo, iCancer Epidemiol Biomarkers Prev, 2019)

Olunye uphononongo olukhulu olwenziweyo luphanda umanyano lokutya kweMagnesium kunye nomngcipheko womhlaza wepancreatic kumadoda nabasetyhini abangama-66,806, abaneminyaka engama-50-76. Uphononongo lufumanise ukuba yonke i-100 mg / yemihla yokuncipha kokutya kweMagnesium yayihambelana nokunyuka kwama-24% kumhlaza wepancreatic. Ke ngoko, ukutya ngokwaneleyo kweMagnesium kunokuba luncedo ekunciphiseni umngcipheko womhlaza wepancreatic. (UDibaba D okqhubekayo, Br J Cancer, 2015)

Ukususwa kweqhoshaUkutya ukutya okune-Magnesium njengenxalenye yokutya okunempilo, okunesondlo kubalulekile ekufumaneni amanqanaba acetyiswayo eMagnesium emizimbeni yethu. Ukuba iyafuneka, inokuncediswa ngezongezo zeMagnesium. Izifundo zeklinikhi zibonisa ukuba amanqanaba asezantsi eMagnesium ayanyaniswa nomngcipheko ophezulu womhlaza wecolorectal kunye neepancreatic cancer. Ngelixa ukutya kweMagnesium kokutya kuluncedo, ukuxhaswa ngokugqithileyo kweMagnesium ngaphaya kwamanqanaba afunekayo kunokuba yingozi.

Yintoni iMagnesium Stearate? Ngaba sisongezelelo?

Umntu akufuneki adideke iMagnesium stearate kunye neMagnesium supplement. I-Magnesium stearate sisongezo sokutya esisetyenziswa ngokubanzi. I-Magnesium stearate yityuwa yemagniziyam ye-asidi enamafutha ebizwa ngokuba yi-stearic acid. Isetyenziswa ngokubanzi kwishishini lokutya njengearhente yokuhamba, i-emulsifier, ibinder kunye ne-thickener, i-lubricant kunye ne-antifoaming agent.

Imagnesium stearate isetyenziselwa ukuvelisa izongezo zokutya kunye namacwecwe amayeza, iifomsile kunye neepowder. Iyasetyenziswa kwimveliso ezininzi zokutya ezinje ngesekile, iziqholo kunye nezinto zokubhaka kunye nezithambiso. Xa ifakiwe, i-magnesium stearate iyaqhekeka kwi-ion yayo yecandelo, i-magnesium kunye ne-stearic kunye ne-acicicic acid. I-Magnesium stearate ine-GRAS (Ngokubanzi yamkelwe njengoKhuseleko) e-United States nakwilizwe liphela. Ukungeniswa kwe-Magnesium stearate, ukuya kuthi ga kwi-2.5g ngekg nganye ngosuku kuthathwa njengokukhuselekileyo. Ukutya kakhulu iMagnesium stearate kunokubangela ukuphazamiseka kwamathumbu kunye nohudo. Ukuba uthathwe phantsi kweedosi ezinconyelwayo, iMagnesium stearate ayinakho ukukhokelela kwiziphumo ezingafunekiyo.

Isondlo samaminerali - iPhosphorus / Phosphate (Pi):

I-Phosphorus isondlo samaminerali esibalulekileyo yinxalenye yokutya okuninzi, ubukhulu becala ikwimo yeephosphates (Pi). Eli candelo lamathambo, amazinyo, iDNA, iRNA, inwebu yeseli ngohlobo lwephospholipids kunye nomthombo wamandla we-ATP (adenosine triphosphate). Ii-enzymes ezininzi kunye nee-biomolecule emzimbeni wethu zenziwe ngephosphorylated.

Isibonelelo esinconywayo semihla ngemihla sePhosphorus sikuluhlu lwe-700-1000 mg yabantu abadala abangaphezulu kweminyaka eli-19 ubudala. Kuqikelelwa ukuba amaMelika athabatha phantse kabini isixa esinconywayo ngenxa yokusebenzisa kakhulu ukutya okucutshungulwayo.

Imithombo yokutya ene-phosphate: Ngokwendalo ikhona ekutyeni okuluhlaza kubandakanya imifuno, inyama, intlanzi, amaqanda, iimveliso zobisi; I-Phosphate ikwafunyanwa njengesongezo kwinani elikhulu lokutya okucutshungulwayo kubandakanya i-burger, ipitsa kunye notywala. Ukongezwa kwePhosphate kunceda ngokwanda komgangatho wokutya okucutshungulwayo, kodwa akudweliswanga njengesixhobo ngasinye. Ke ngoko, ukutya okunezongezo zePhosphate akukho kuphela i-70% ephezulu yePhosphate kunokutya okuluhlaza kwaye kunegalelo kwi-10-50% yokutya kwe-phosphorus kumazwe aseNtshona. (Iphepha leNIH.gov)

Ukutya kwePhosphorus kunye nomngcipheko womhlaza:  Kwisifundo sokulandelwa seminyaka engama-24 kumadoda angama-47,885 asekwe kuhlalutyo lwedatha yokutya exeliweyo, kwafunyaniswa ukuba ukutya okuninzi kwe-phosphorus kunxulunyaniswa nomngcipheko owandileyo wenqanaba lokuqhubela phambili kunye nomhlaza webanga le-Prostate. (UWilson KM okqhubekayo, Am J Clin Nutr., 2015)  

Olunye uphononongo olukhulu lwabemi eSweden lufumene umngcipheko womhlaza ophakamileyo kunye namanqanaba okwanda kwePhosphates. Emadodeni, umngcipheko womhlaza wepancreas, imiphunga, idlala lengqula kunye nethambo wawuphezulu ngelixa kwabasetyhini, kukho umngcipheko owandileyo onxulunyaniswa nomhlaza womhlaza wesifo somhlaza, semiphunga kunye nomhlaza wesikhumba somhlaza. (UWulaningsih W okqhubekayo, Umhlaza weBMC, 2013)

Uvavanyo oluvavanyiweyo lubonise ukuba xa kuthelekiswa neempuku ezazityiswa ukutya okuqhelekileyo, iigundane zondla ukutya okuphezulu e-Phosphates ziye zonyusa ukuqhubela phambili kokukhula kwamathumbu emiphunga kunye nokukhula, oko ke kudibanisa i-Phosphate ephezulu kumngcipheko ophezulu womhlaza wemiphunga. (UJin H et al, NdinguJ J wokuphefumla kunye noKhathalelo oluBalulekileyo, 2008)

Ukuthatha okubalulekileyo:  Iingcebiso zesondlo kunye neengcebiso malunga nokutya ukutya kwendalo kunye nemifuno kunye nokutya okuncinci okucutshungulwayo kunceda ekugcineni amanqanaba ePhosphate kuluhlu olufunekayo olusempilweni. Amanqanaba angaqhelekanga e-Phosphate ahambelana nokwanda komngcipheko womhlaza.

Isondlo samaminerali - iZinc (Zn):

I-Zinc sisimbiwa esifanelekileyo samaminerali esikhona kwindalo ethile ekutyeni kwaye siyabandakanyeka kwimimandla emininzi yemetabolism yeselula. Kuyimfuneko ukuba umsebenzi wokunyusa ii-enzymes ezininzi. Idlala indima ekusebenzeni komzimba, kwiprotein synthesis, kwi-DNA synthesis kunye nokulungisa, ukuphilisa amanxeba kunye nokwahlula iiseli. Umzimba awunayo inkqubo ekhethekileyo yeZinc yokugcina, yiyo loo nto kufuneka igcwaliswe ngokutya yonke imihla iZinc ngokutya.

Isibonelelo esinconywayo semihla ngemihla seZinc ngokutya ukutya / izongezo zikuluhlu lwe-8-12mg yabantu abadala abangaphezulu kweminyaka eli-19 ubudala. (NIH.gov sheetheet) Ukusilela kwe-Zinc yingxaki yezempilo yehlabathi echaphazela abantu abangaphezulu kwezigidi ezi-2 kwihlabathi liphela. (UWessell KR okqhubekayo, PLoS One, 2012; UBrown KH okqhubekayo, Ukutya okunesondlo. IBull., 2010) Ukuthatha iZinc ukutya okutyebileyo kumanani afanelekileyo kungoko kubalulekile.

Imithombo yokutya ene-zinc: Iintlobo ngeentlobo zokutya zineZinc, kubandakanya iimbotyi, amandongomane, iintlobo ezithile zokutya kwaselwandle (njengenkala, ilobster, oyster), inyama ebomvu, iinkukhu, iinkozo ezigcweleyo, ukutya okuziinkozo kwasekuseni okuqinileyo, kunye neemveliso zobisi.  

Ukutya kweZinc kunye nomngcipheko womhlaza:  Iziphumo zomhlaza ezichasene ne-Zn ikakhulu zinxulunyaniswa ne-anti-oxidant kunye nepropathi yokuthintela ukudumba. (Wessels I et al, Nutrients, 2017; Skrajnowska D et al, Nutrients, 2019) Kukho izifundo ezininzi ezichaze umbutho wokusilela kweZinc (ngenxa yokutya kancinci ukutya okunezityebi zeZinc) ngomngcipheko owandileyo womhlaza, njengoko kudwelisiwe ngezantsi :

• Icandelo elilawulwa yimeko yophando ePhononongo lwaseYurophu kwiCancer and Nutrition cohort ifumene umbutho wamanqanaba anyukayo e-Zinc amaminerali kunye nokwehla komngcipheko wesifo somhlaza wesibindi (hepatocellular carcinoma). Abazange bafumane nxu lumano lwamazinga e-Zinc kunye ne-bile duct kunye ne-cancer ye-gall bladder. (Stepien M wt al, Br J Umhlaza, 2017)
• Kwakukho ukwehla okubonakalayo kumanqanaba e-serum Zinc afunyanwa kwizigulana ezinomhlaza wamabele xa zisanda kuthelekiswa namavolontiya asempilweni. (UKumar R okqhubekayo, J Umhlaza Res. Ther., 2017)
• Kwiqela laseIran, bafumene inqanaba lokuncipha kwe-Zum ye-serum kwizigulana ezinomhlaza ngokungafaniyo nolawulo olusempilweni. (Khoshdel Z okqhubekayo, Biol. Trace Elem. Res., 2015)
• Uhlalutyo lwe-meta luxele amanqanaba e-Zinc asezantsi kakhulu kwizigulana ezinomhlaza wemiphunga nolawulo olusempilweni. (UWang Y okqhubekayo, Ilizwe J oSurg. IOncol., 2019)

Imikhwa efanayo yamanqanaba asezantsi eZinc axeliwe kwezinye iisifo somhlaza kubandakanya intloko nentamo, isibeleko, idlala lengqula, iprostate kunye nabanye.

Ukuthatha okubalulekileyo:  Ukugcina amanqanaba afunekayo e-Zinc ngokutya / ukutya okutyayo kwaye ukuba kufuneka ukongezwa okubalulekileyo ekuxhaseni inkqubo yomzimba yokuzikhusela kunye ne-antioxidant eyomeleleyo, ngoyena ndoqo wokuthintela umhlaza. Akukho nkqubo yogcino zinki emizimbeni yethu. Ke ngoko iZinc kufuneka ifumaneke ngokutya / ukutya. Ukuxhaswa okugqithisileyo kweZinc ngaphaya kwamanqanaba afunekayo kunokuba neziphumo ezibi ngokucinezela amajoni omzimba. Ukuthatha isixa esifunekayo se-Zn ngokutya ukutya okune-Zinc etyebileyo endaweni yokutya kakhulu izongezo kunokuba luncedo.

Isondlo seSelenium (Se):

I-Selenium yinto elandelwayo ebalulekileyo kwisondlo sabantu. Idlala indima enkulu ekukhuseleni umzimba kumonakalo we-oxidative kunye nosulelo. Ukongeza, ikwadlala indima ebalulekileyo ekuzaleni kwakhona, kwi-thyroid metabolism metabolism kunye ne-DNA synthesis.

Isibonelelo semihla ngemihla esicetyiswayo seSelenium ngokusebenzisa isondlo ngama-55mcg kubantu abadala abangaphezulu kweminyaka eli-19 ubudala. (Iphepha leenkcukacha ze-NIH.gov) 

Imithombo etyebileyo yokutya / kwemithombo yesondlo:  Isixa seSelenium esifunyenwe kukutya kwendalo / isondlo sixhomekeke kubungakanani beSelenium ekhoyo emhlabeni ngexesha lokukhula, ke ngoko iyahluka kukutya okwahlukeneyo okuvela kwimimandla eyahlukeneyo. Nangona kunjalo, umntu uyakwazi ukuzalisekisa iimfuno zeselenium ngokutya amantongomane eBrazil, isonka, igwele labapheki, igalikhi, amatswele, iinkozo, inyama, iinkukhu, intlanzi, amaqanda kunye neemveliso zobisi.

Isondlo seSelenium kunye nomngcipheko womhlaza:  Amanqanaba asezantsi eSelenium emzimbeni adityaniswa nomngcipheko okhulayo wokufa kunye nokusebenza kakubi komzimba. Izifundo ezininzi zibonise izibonelelo zamanqanaba aphezulu e-Selenium amaminerali kumngcipheko we-Prostate, lung, cololoalal kunye nomhlaza wesinyi. (URayman MP, uLancet, 2012)

Izongezo zeSelenium ze-200mcg / ngemini zinciphisa izehlo zomhlaza webala le-Prostate ngama-50%, izehlo zomhlaza wemiphunga nge-30%, kunye neziganeko zomhlaza obalaseleyo nge-54% (Reid ME et al, Nutrition & Cancer, 2008) Kubantu abasempilweni abangafumaniswanga ukuba banomhlaza, kubandakanya ne-Selenium njengenxalenye yesondlo kwaxelwa ukomeleza ukhuseleko lwabo ngokwandisa umsebenzi weeseli zombulali zendalo. (UBüntzel J et al, iAnticancer Res., 2010)

Ukongeza, ukutya okutyebileyo kwi-selenium kuyanceda umhlaza izigulana ngokunciphisa ubuthi obunxulumene nechemotherapy. Ezi zongezo zaboniswa zisezantsi kakhulu amazinga osulelo kwizigulane ezingezizo iHodgkin's Lymphoma. (Asfour IA et al, Biol. Trace Elm. Res., 2006) Isondlo se-selenium siye saboniswa ukunciphisa i-chemo ethile ebangela ubutyhefu bezintso kunye nokunciphisa umongo wamathambo (Hu YJ et al, Biol. Trace Elem. Res., 1997), kunye nokunciphisa ubuthi obubangelwa yimitha yobunzima bokuginya. (Büntzel J et al, i-Anticancer Res., 2010)

Ukuthatha okubalulekileyo:  Zonke izibonelelo ezichasene nomhlaza zeSelenium zinokusebenza kuphela ukuba amanqanaba eSelenium kuloo mntu sele ephantsi. Ukongezwa kwe-Selenium kubantu esele benayo ngokwaneleyo i-Selenium emzimbeni wabo kunokukhokelela kumngcipheko wohlobo lweswekile 2. (I-Rayman MP, i-Lancet, i-2012) Kwezinye i-cancer ezifana ne-mesothelioma tumors, i-Selenium supplementation iboniswe ukuba ibangele ukuqhubela phambili kwezifo. (URose AH okqhubekayo, Am J Pathol, 2014)

Isondlo samaminerali - iCopper (Cu):

I-Copper, into ebalulekileyo yokulandela umkhondo wezimbiwa, iyabandakanyeka kwimveliso yamandla, imetabolism yentsimbi, ukusebenza kwe-neuropeptide, ukudityaniswa kwezicubu kunye ne-neurotransmitter synthesis. Iyabandakanyeka kwiinkqubo ezininzi ze-physiologic kubandakanya i-angiogenesis (eyenza imithambo yegazi emitsha), ukusebenza kwamajoni omzimba, ukhuselo lwe-antioxidant, ukulawulwa kwembonakalo yemfuza nabanye. 

Isibonelelo semihla ngemihla seCopper esinconywayo siyi-900-1000mcg yabantu abadala abangaphezulu kweminyaka eli-19 ubudala. (NIH.gov sheetheet) Sinokufumana isixa esifunekayo seCopper kwizidlo zethu.

Imithombo yokutya ecebile ngeCopper: Ubhedu bungafunyanwa kwiimbotyi ezomisiweyo, iiamangile, enye imbewu kunye namandongomane, i-broccoli, igalikhi, iimbotyi zesoya, ii-ertyisi, iinkozo ze-ngqolowa, iimveliso zeenkozo, itshokholethi kunye nokutya kwaselwandle.

Ukutya ubhedu kunye nomngcipheko womhlaza: Kukho izifundo ezininzi ezibonise ukuba uxinzelelo lweCopper kwi-serum kunye neetissue tishu luphezulu kakhulu kunolo lwezifundo ezisempilweni. (Gupta SK okqhubekayo, J Surg. Oncol., 1991; UWang F et al, uCurr Med. Chem, 2010) Uxinzelelo oluphezulu lwezimbiwa zeCopper kwizihlunu zethumba kungenxa yendima yalo kwi-angiogenesis, inkqubo ephambili efunekayo ukuxhasa iiseli zomhlaza ezikhula ngokukhawuleza.

Uhlalutyo lwe-meta lwezifundo ezili-14 luxele ubungqina obubonakalayo bamanqanaba aphezulu obhedu be-serum kwizigulana ezinomhlaza womlomo wesibeleko kunolawulo lwezifundo ezisempilweni, ukuxhasa umbutho wamanqanaba aphezulu e-serum Copper njengomngcipheko womhlaza womlomo wesibeleko. (UZhang M, Biosci. Rep., 2018)

Olunye uphononongo olupapashwe kwi-Proceedings of the National Academy of Science e-United States, luchaze indlela amanqanaba aguqukayo eCopper kwi-tumor microenvelo, eguqula isisu semetabolism kwaye akhuthaze ukukhula kwethumba. (UIshida S okqhubekayo, PNAS, 2013)

Ukuthatha okubalulekileyo:  ICopper yinto ebalulekileyo esiyifumana kwizidlo zethu. Nangona kunjalo, amanqanaba agqithisileyo ezimbiwa zeCopper ngenxa yamanqanaba aphakamileyo emanzini okusela okanye ngenxa yesiphene kwiCopper metabolism, anokunyusa umngcipheko womhlaza.

isiphelo  

Imithombo yokutya kwindalo isinika isixa esifunekayo sezondlo zeminerali kwimpilo yethu nokuba sempilweni. Kunokubakho ukungalingani ngenxa yokutya okungenamsoco, ukutya okucutshungulwayo, ukuhluka komxholo womhlaba ngokusekelwe kwiindawo zendawo, ukuhluka kwamanqanaba amaminerali kumanzi okusela kunye nezinye izinto zokusingqongileyo ezinokubangela ukuhluka kwimixholo yamaminerali. Iqondo eligqithisileyo leeminerali ezithathwa njengeCalcium, iPhosphorus kunye neCopper; kunye namanqanaba anqongopheleyo eeminerali anje ngeMagnesium, iZinc (ukutya okuphantsi kweZinc ukutya okutyebileyo) kunye neSelenium, anxulunyaniswa nomngcipheko owongeziweyo. umhlaza. Kufuneka sijonge ukutya okuphezulu kweZinc, Magnesium kunye neSelenium kwaye sikuthathe ngokwemiyinge efanelekileyo. Omnye akufanele adide i-magnesium stearate yezongezelelo ze-magnesium. Kwakhona, nciphisa ukuthathwa kweeminerali zezondlo ezifana neCalcium, iPhosphorus kunye neCopper ukuya kwizixa ezicetyiswayo zokunciphisa umngcipheko womhlaza. Ukutya okunempilo okunokulinganisela kokutya kwendalo liyeza lokugcina amanqanaba acetyiswayo ezondlo zeminerali ezibalulekileyo emzimbeni wethu ukuze uhlale kude nomhlaza.

Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.

Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.

Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.

Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) lolona nyango lwendalo olungcono lomhlaza kunye nokunxulumene nonyango imiphumela.

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