Iimbalasane
Uphononongo lwakutsha nje olwenziwe e-China kwizigulana ezindala ze-Acute Myeloid Leukemia (AML) lubonise oko Ukongezwa kweVitamin C/ ukunyuswa kwandisa ukuphendula kweziyobisi ze-hypomethylating i-Decitabine (i-Dacogen) ukusuka kwi-44% ukuya kwi-80% kwezi umhlaza izigulane. Ngenxa yoko, ukudibanisa umthamo ophezulu we-Vitamin C kunye / okanye ukutya okucebileyo kwi-Vitamin C kunye ne-Decitabine ingaba yinto efanelekileyo yokuphucula amazinga okuphendula kwizigulane ze-Leukemia (AML) ezikhulileyo.
I-Vitamin C / iAccorbic Acid
I-Vitamin C yi-antioxidant eyomeleleyo kunye ne-booster immune efanelekileyo. Kwakhona kwaziwa ngokuba yi-ascorbic acid. UVitamin C yivithamini ebalulekileyo, yiyo ke loo nto ifunyanwa ngokutya okusempilweni. I-Vitamin C ifumaneka kakhulu kwiziqhamo nakwimifuno. Ukunqongophala kokutya iVitamin C kunokubangela ukunqongophala kweVitamin-C ebizwa ngokuba siscurvy.
Imithombo yokutya yeVitamin C
Oku kulandelayo kukutya okunotyebileyo kwiVitamin C:
- Iziqhamo zeCitrus kubandakanya iiorenji, iilamuni, iidiliya, iipomelos, kunye nealam.
- guava
- Ipepile eluhlaza
- Ipelepele ebomvu
- Ierberberries
- Isiqhamo se-Kiwi
- Ipapaya
- Ipanapula
- Ijusi yetamatisi
- Iipatata
- Ibrokholi
- I-Cantaloupes
- Iklabishi ebomvu
- Ispinatshi
I-Acute Myeloid Leukemia (AML) kunye neDecitabine / iDacogen
Kukho amachiza athile e-chemo asetyenziselwa izibonakaliso ezahlukeneyo zomhlaza. I-Decitabine/Dacogen lelinye ichiza le-chemo elisetyenziselwa ukunyanga i-acute myeloid leukemia (AML), enqabileyo kodwa ebaluleke kakhulu. umhlaza egazini kunye nomongo wethambo. I-leukemia ibangela ukuba iiseli ezimhlophe zegazi zikhule ngokukhawuleza nangokungaqhelekanga, kwaye zixinanisela ngaphandle kwezinye iindidi zeeseli zegazi ezifana neeseli ezibomvu zegazi ezithwala ioksijini kunye neeplatelet ezinceda ekubambeni igazi. Kwaneeseli ezimhlophe zegazi ezingaqhelekanga azikwazi ukwenza umsebenzi wazo wesiqhelo wokulwa usulelo kwaye ukwanda kwazo okungaqhelekanga kuqale kuchaphazele amanye amalungu. 'Acute AML' ichaza ukukhula ngokukhawuleza kolu hlobo lomhlaza. Ke le meko iqhubela phambili ngokukhawuleza kwaye ineziphumo ezibi kunye nokusinda okuphakathi konyaka nje omnye (I-Klepin HD, iklinikhi yeGeriatr Med. Ngo-2016).
Esinye sezizathu ezisisiseko zophuhliso lwe i cancer ngokubanzi kunye ne-leukemias ngokukodwa kukuba ukhuselo, iindlela zokulungisa iimpazamo ngaphakathi kweseli, phantsi kolawulo lwe-tumor suppressor genes kwi-DNA, zicinywa ngokutshintshwa kokuguqulwa okubizwa ngokuba yi-methylation. Olu tshintsho lwe-methylation lusetyenziswa kwindalo ukuprinta imemori ekhethekileyo yeyiphi imfuza kunye nemisebenzi yokuvula okanye ukucima kwizigaba ezahlukeneyo zokukhula kweeseli ezenza imisebenzi ekhethekileyo. Iiseli zomhlaza zikhetha oku kutshintsha kwe-methylation kwaye ziyisebenzise ngokugqithisileyo ukucima i-tumor suppressor gene ezivumela ukuba ziqhubeke ziphindaphinda zingajongwa kwaye zingathintelwa.
Ukutya okuTyiwa emva kokuChongwa koMhlaza!
Akukho mhlaza mibini ifanayo. Yiya ngaphaya kwezikhokelo zesondlo esiqhelekileyo kuwo wonke umntu kwaye wenze izigqibo ezizezakho malunga nokutya kunye nezongezo ngokuzithemba.
UVitamin C uphucula impendulo yeDecitabine kwizigulana ezinomhlaza wegazi
Enye ye-chemotherapy ye-AML yiklasi leziyobisi ezibizwa ngokuba yi-'hypomethylating agents 'i-HMA ethintela olu tshintsho lwe-methylation ukwenza ukuba kusebenze kwakhona i-tumor suppressor genes ukulawula i-leukemia. I-Decitabine yenye yeziyobisi ze-HMA ezisetyenziselwa i-AML. Amachiza e-HMA asetyenziselwa abaguli abakhulileyo be-AML abangaphezulu kweminyaka engama-65 kwaye abanakho ukumelana nokunyanga okunyanga ngamayeza okusetyenziselwa i-AML. Amaxabiso okuphendula kula machiza aphantsi ngokubanzi, kuphela malunga ne-35-45% (UWelch JS okqhubekayo, uEngl J Med omtsha. Ngo-2016). Uphononongo lwakutsha nje olwenziwe e-China, kuvavanye ifuthe lokufaka i-Vitamin C infusions kunye ne-Decitabine kwizigulana ezinomhlaza zabantu abadala abane-Acute Myeloid Leukemia phakathi kweqela elithatha kuphela i-Decitabine kunye nelinye iqela elithatha i-Decitabine kunye ne-Vitamin C. Iziphumo zabo zibonise ukuba ukumiliselwa kwe-Vitamin C Ngokwenyani baneziphumo zokunxibelelana neDecitabine njengoko abaguli abanomhlaza be-AML abathathe unyango oludibeneyo banomgangatho opheleleyo wokuxolelwa nge-79.92% xa kuthelekiswa ne-44.11% kwabo babengenayo i-Vitamin C eyongezelelweyo (UZhao H et al, Leuk Res. Ngo-2018). Isizathu sesayensi sendlela uVitamin C ayiphucule ngayo impendulo yeDecitabine yagqitywa kwaye yayingengomphumela nje wamathuba. Ukutya okutyebileyo kwiVitamin C kunokuba kuhle ekuphuculeni impendulo kunyango kwizigulana zeLeukemia eziphathwe ngeDecitabine.
isiphelo
Ngelixa iVitamin C isetyenziswa ngokubanzi njengenxalenye yokutya okunezondlo, olu phononongo lubonakalisile ukuba indibaniselwano yedosi ephezulu kakhulu yeVitamin C kunye neDecitabine inokubutshintsha ubomi kwizigulana esele zikhulile ezine-Acute Myeloid Leukemia. I-Vitamin C inokufumaneka ngokwendalo kwiziqhamo ze-citrus kunye nemifuno eyahlukeneyo enje ngesipinatshi kunye neletisi okanye ifunyenwe kwizongezo zeVitamin ezinokuthengwa phezu kwekhawuntari. Ukubandakanya uVitamin C njengenxalenye yokutya kunokuba luncedo kwizigulana ezinomhlaza ngokuphucula unyango (iDititabine) impendulo. Oku kugxininisa ukuba iimveliso zendalo ezikhethiweyo zinokuncedisa i-chemotherapy ukuphucula amathuba okuphumelela kunye nokuba sempilweni kwesigulana.
Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.
Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.
Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.
ISondlo esiSiqu soMhlaza!
Umhlaza uyatshintsha ngokuhamba kwexesha. Yenza ngokwezifiso kwaye uguqule isondlo sakho ngokusekwe kwisalathiso somhlaza, unyango, indlela yokuphila, ukhetho lokutya, i-allergies kunye nezinye izinto.
Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) sesona sixhobo sendalo somhlaza kunye neziphumo ebezingalindelekanga zonyango.