Liphello Tse Khahlanong le Kankere tsa "Apigenin"

Lintlha-khōlō Tsa

Apigenin, tlatsetso ea tlhaho e tlisoang ke semela e fumanoang meroho e tloaelehileng, litholoana, litlama le lino tse tahang e tsebahala ka ho ba le melemo e fapaneng ea bophelo bo botle ka lebaka la litlamorao tsa eona tse khahlano le mofets'e le lithibela-mafu. Liphuputso tse ngata tsa laboratori li bontšitse kamoo Apigenin e ka thusang ho thibela lisele tsa mofets'e le hore na e ka hokahana joang le chemotherapy e khethehileng mefuteng ea mofetše e kang prostate, pancreatic, gastric le mefuta e meng ea mofetše..

Lefu la seoa la tlhahlobo ea mofets'e ke ketsahalo e fetolang bophelo e lebisang motho ho botjha le ho fetola mokhoa oa hae oa bophelo le khetho ea lijo. Leha taba ea hore chemotherapy e ntse e le e 'ngoe ea mekhoa e metle ea kalafo ea ho alafa mofets'e, bakuli ba hlokolosi ka litaba tse ngata tse amanang le chemo haholo-holo litlamorao tse kholo le boleng ba bophelo. Mokuli oa mofets'e o batla mekhoa efe kapa efe ea kalafo ka chemotherapy, ho ntlafatsa "mathata a bona a katleho". E 'ngoe ea likhetho tse joalo ke ho eketsa litlatsetso tsa tlhaho le litlama tse sebelisitsoeng mekhoeng ea meriana ea setso lefats'eng ka bophara, bakeng sa matla a bona a ho itšireletsa mafung le ho folisa (pheko ea tlhaho bakeng sa mofets'e). The modus operandi bakeng sa ba bangata tsoaroa ke kankere bakuli ke khetho e sa reroang ea lihlahisoa tsa tlhaho tse tsoang ho limela tse nang le litlamorao tse khahlanong le mofets'e tseo ba qalang ho li nka, ka maikutlo a hore li tla ba thusa ho sebetsana hantle le litla-morao ntle le ho eketsa moroalo oa chefo le ho ntlafatsa menyetla ea bona ea ho se be le mofets'e. pholoho. E 'ngoe ea lihlahisoa tse joalo tsa tlhaho ke flavonoid e bitsoang Apigenin.

Apigenin le Mehloli ea eona ea Lijo

Apigenin ke flavonoid (flavone) ea lijo e fumanoang limeleng tse ngata, litholoana, meroho le lino tse kenyelletsang:

• Chamomile tee
• parsley
• Seleri
• Sepinichi
• letsatsi
• kharenate
• spearmint
• Basil
• oregano
• Fenugreek
• Konofolo
• Veine e khubelu

Apigenin e bapala karolo ea bohlokoa kalafong ea litlama ea China.

Ts'ebeliso e rehiloeng / Melemo ea bophelo ea Apigenin

Joalo ka lihlahisoa tse ngata tsa tlholeho tse sebelisoang moetlo, hoa tsebahala hore Apigenin e na le mesebetsi e matla e thibelang ho ruruha, antioxidant, antibacterial le antiviral mme ka hona e nkuoa e na le melemo e mengata ea bophelo bo botle. Melemo e meng ea tšebeliso ea bophelo / bophelo bo botle ba Apigenein e kenyelletsa:

• E ka fokotsa khatello ea maikutlo / matšoenyeho le boroko (ho hloka boroko)
• E kanna ea ba le litlamorao tse khahlano le lefu la tsoekere
• E kanna ea ba le phello ea ts'ireletso ea methapo
• E kanna ea ba le thepa ea anti-cancer
• E ka thusa ho fokotsa khatello ea mali

Liphello / Melemo ea Anti-Cancer / Apigenin

Lithuto tse pharaletseng tse entsoeng ka mefuta e mengata ea tsoaroa ke kankere mela ea lisele le mehlala ea liphoofolo tse sebelisang Apigenin li bontšitse liphello tsa eona tse khahlanong le mofetše. Botle ba li-flavonoids tse kang Apigenin ke hore ha e khone feela ho thusa mehatong ea thibelo ea mofetše ho fokotsa kotsi e ka bang teng ea ho ba le hlahala, empa hape e khona ho sebetsa ka tumellano le li-chemotherapies tse ling ho ntlafatsa katleho ea moriana.Yan le al, Cell Biosci., 2017).

Mehlala e fokolang ea litlamorao tsa kankere ea Apigenin

Mehlala e meng ea tsoaroa ke kankere liketso tsa thibelo ea Apigenin le likamano tsa eona le chemotherapy mefuteng e itseng ea mofetše li totobatsoa ka tlase.

Phello ea Apigenin ho Kankere ea mala

Tabeng ea mofetše oa mala, Apigenin e fumanoe e baka lefu la sele le ho sitisa kholo ea methapo e mecha ea mali e thusang hlahala ho hola. Ntle le moo, Apigenin o entse hore tikoloho ea hlahala e be bora le ho feta ka ho fokotsa ts'oaetso ea tsoekere ke lisele tsa mofetše, ho sitisa ntlafatso ea matrix kantle le ho potoloha sele ea mofets'e, le ho thibela lits'ebetso tse khothalletsang tsoelo-pele ea mofetše le ho ataLefort EC et al, Mol Nutr Food Res., 2013). 

Phello ea ho nka Apigenin hammoho le Gemcitabine Chemotherapy bakeng sa Kankere ea Pancreatic - Lithuto tsa liteko

• Phuputso e entsoeng ke bafuputsi ba tsoang Seoul National University College of Medicine Korea e fumane hore apigenin e ntlafatsa katleho ea anti-hlahala ea gemcitabine kankere ea pancreatic. (Lee SH et al, Kankere Lett., 2008)
• Phuputso e 'ngoe e entsoeng ke bafuputsi ba tsoang Feinberg School of Medicine e Chicago le eona e fumane hore ho sebelisa apigenin hammoho le gemcitabine ho thibela kholo ea lisele tsa mofetše oa pancreatic le ho baka lefu la kankere ea lefu (apoptosis). (Strouch MJ le al, Pancreas, 2009)

Ka bokhutšoanyane, lithuto tse ngata tse sebelisang setso le mefuta ea liphoofolo li fumane hore Apigenin e ka etsa hore matla a gemcitabine chemotherapy a be thata ho phekola mofets'e oa pancreatic.

Phello ea ho nka Apigenin hammoho le Cisplatin Chemotherapy - Boithuto ba Boiteko

Phuputsong e entsoeng ke bafuputsi ba tsoang Univesithing ea Trakya naheng ea Turkey, Apigenin ha e kopantsoe le chemo drug Cisplatin e ntlafalitse phello ea eona ea cytotoxic liseleng tsa mofetše oa senya (phello e khahlanong le mofets'e ea Apigenin), le mekhoa ea ts'ebetso ea limolek'hule ea Apigenin. (Erdogan S et al, Biomed Pharmacother., 2017).

fihlela qeto e

Lithuto tse fapaneng tsa liteko li fana ka maikutlo a matla a anti-mofets'e / melemo ea apigenin. Leha ho le joalo, liphetho tse tsoang lithutong tsena tsa liteko ha lia netefatsoa litekong tsa batho. Hape, ka tlhokomeliso, taba ea hore sehlahisoa sa tlhaho se kang Apigenin se khona ho ba le tšusumetso e tebileng joalo boemong ba lisele tsa cellular e boetse e bolela hore e ka ba le liphello tse mpe ho phekolo ea kankere ea motho haeba e sebelisoa ka motsoako o fosahetseng oa lithethefatsi tsa chemo. Ho feta moo, Apigenin ho ba antioxidant e ka kena-kenana le lithethefatsi tsa chemo tse sebelisang mochini oa ho eketsa tšenyo ea oxidative liseleng tsa mofetše ha e nkuoa ka nako e le 'ngoe le chemo, athe liphuputso li bonts'itse hore kalafo ea pele le Apigenin pele ho chemo e bile le phello e ntle. Ka hona, ho bohlokoa hore tsoaroa ke kankere Bakuli ba lula ba buisana le litsebi tsa bophelo bo botle mabapi le lijo tsa bona le tšebeliso ea li-supplement tsa tlhaho ha ba fuoa phekolo ea lik'hemik'hale ho e-na le ho khetha ka tšohanyetso ho latela likhothaletso tse tsoang ho ba lelapa le metsoalle.

Lijo tseo u li jang le tse u tlatsetsang ke qeto eo u e etsang. Qeto ea hau e lokela ho kenyelletsa ho nahanisisa ka liphetoho tsa liphatsa tsa lefutso tsa mofetše, e leng mofetše, kalafo e tsoelang pele le litlatsetso, ho kula hohle, leseli la bophelo, boima, bolelele le litloaelo.

Morero oa phepo e nepahetseng bakeng sa mofets'e ho tsoa addon ha o ea ipapisa le lipatlisiso tsa inthanete. E iketsetsa liqeto bakeng sa hau e ipapisitse le mahlale a limolek'hule a kentsoeng tšebetsong ke bo-rasaense ba rona le lienjineri tsa software. Ho sa tsotelehe hore na o tsotella ho utloisisa metheo ea limolek'hule kapa che - bakeng sa moralo oa phepo ea mofets'e kutloisiso ea hlokahala.

Qala hona joale ka moralo oa hau oa phepo e nepahetseng ka ho araba lipotso lebitsong la mofetše, phetoho ea lefutso, kalafo e tsoelang pele le litlatsetso, ho kula hohle, litloaelo, mokhoa oa bophelo, sehlopha sa lilemo le bong.

Bakuli ba mofets'e hangata ba tlameha ho sebetsana le tse fapaneng litla-morao tsa chemotherapy tse amang boleng ba bona ba bophelo le ho batla mekhoa e meng ea kalafo ea mofets'e. Ho nka phepo e nepahetseng le litlatsetso ho latela maikutlo a mahlale (ho qoba ho inahanela le ho khetha ka mokhoa o sa reroang) ke pheko ea tlholeho bakeng sa mofets'e le litla-morao tse amanang le kalafo

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