Lintlha-khōlō Tsa
Liphuputso tse 'maloa tse fokolang tsa bongaka li fumane hore Coenzyme Q10 / CoQ10 / ubiquinol supplementation e ka ba le melemo ho mefuta e fapaneng ea mofets'e joalo ka mofets'e oa matsoele, leukemia, lymphoma, melanoma le mofetše oa sebete ka ho fokotsa maemo a tšoaetso ea cytokine maling, ho ntlafatsa boleng ba bophelo, ho fokotsa litla-morao tsa kalafo tse kang cardiotoxicity, ho fokotsa ho ipheta kapa ho ntlafatsa ho phela. Kahoo, ho nka lijo tse ruileng tsa Coenzyme Q10 / CoQ10 ho ka ba molemo ho bakuli bana ba mofets'e. Liphetho li hloka ho netefatsoa lithutong tse kholo.
Coenzyme Q10 / Co-Q10 ke eng?
Coenzyme Q10 (Co-Q10) ke k'hemik'hale e entsoeng ka tlhaho ke 'mele ea rona mme ea hlokahala bakeng sa kholo le tlhokomelo. E na le thepa e matla ea antioxidant hape e thusa ho fana ka matla liseleng. Sebopeho se sebetsang sa Co-Q10 se bitsoa ubiquinol. Ka lilemo, tlhahiso ea Co-Q10 'meleng ea rona ea fokotseha. Kotsi ea mafu a mangata, haholo nakong ea botsofali le eona e fumanoe e amana le ho theoha ha maemo a Coenzyme Q10 (Co-Q10).
Mehloli ea Lijo ea Coenzyme Q10 / Coq10
Coenzyme Q10 kapa CoQ10 le eona e ka fumanoa lijong tse kang:
- Litlhapi tse mafura tse kang saalmon le mackerel
- Lijo tse kang nama ea khomo le nama ea kolobe
- Meroho e kang broccoli le cauliflower
- Linate tse kang makotomane le li-pistachio
- Peo ea Sesame
- Lijo tsa nama tse kang sebete sa kana, pelo ea kana, sebete sa nama ea khomo jj.
- Litholoana tse kang fragole
- Li-soya
Ntle le mehloli ea lijo tsa tlholeho, Coenzyme-Q10 / CoQ10 e boetse e fumaneha e le li-supplement tsa phepo e le li-capsules, matlapa a chewable, li-syrups tse metsi, liphaphatha hape e le liente tse kenang methapong.
Melemo e akaretsang ea bophelo bo botle ba Coenzyme Q10 / Co-Q10 / Ubiquinol
Coenzyme Q10 (CoQ10) e tsejoa e na le melemo e mengata e fapaneng ea bophelo bo botle Ho latela tse ling tsa melemo ea bophelo bo botle ba Coenzyme Q10 (Co-Q10):
- E ka thusa ho fokotsa kotsi ea mafu a pelo
- E ka thusa ho fokotsa migraine
- E kanna ea thusa bokong mme ea thusa ho fokotsa matšoao a mafu a Alzheimer's le Parkinson
- E ka thusa ho phekola thari
- E ka thusa ho fokotsa k'holeseterole
- E ka thusa ho ntlafatsa ts'ebetso ea 'mele ho batho ba bang ba nang le lefu la ho senyeha ha mesifa (sehlopha sa mafu se bakang bofokoli bo tsoelang pele le tahlehelo ea mesifa).
- E ka thusa ho thibela lefu la tsoekere
- E kanna ea matlafatsa sesole sa 'mele
- E ka sireletsa pelo ho tsoa tšenyo e bakiloeng ke lithethefatsi tse ling tsa chemotherapy
Liphuputso tse ling li boetse li bontša hore maemo a phahameng a Coenzyme Q10 a ka fana ka melemo e amanang le ho fokotsa kotsi ea mafu a itseng ho kenyeletsa le a mang tsoaroa ke kankere mefuta.
Lijo Tseo U ka li Jang Kamora Ho Khetholla Kankere!
Ha ho kankere tse peli tse tšoanang. Fetela ka n the'ane ho tataiso e tloaelehileng ea phepo bakeng sa motho e mong le e mong 'me u etse liqeto tse ikhethileng mabapi le lijo le li-supplement ka kholiseho.
Litla-morao tsa Coenzyme Q10 / Ubiquinol
Ho nka lijo tse ruileng tsa Coenzyme Q10 / CoQ10 ka kakaretso ho bolokehile ebile hoa mamelleha. Leha ho le joalo, ts'ebeliso e fetelletseng ea Coenzyme Q10 e ka baka litla-morao tse ling ho kenyelletsa:
- Nausea
- Sehlōhō
- Letšollo
- Ho senya
- Bohloko ba mpa
- Ho hloka boroko
- Ho lahleheloa ke takatso ea lijo
Batho ba bang ba boetse ba tlaleha litla-morao tse ling tsa Coenzyme Q10 joalo ka makhopho a letlalo.
Coenzyme Q10 / Ubiquinol le Kankere
Coenzyme Q10 e hapile thahasello e itseng sechabeng sa mahlale kaha batho ba baholo le batho ba nang le maemo a bongaka ka kakaretso ba ne ba e-na le maemo a tlase a CoQ10. Ho tloha tsoaroa ke kankere e ne e boetse e atile har'a batho ba baholo mme kotsi ea mofets'e e eketseha ka lilemo, e lebisitse lithutong tse fapaneng ho lekola hore na enzyme ena e ka ba le litlamorao life 'meleng. Ka tlase ke mehlala ea lithuto tse ling tse entsoeng ho lekola kamano lipakeng tsa Coenzyme Q10 le mofets'e. Ha re shebeng lithuto tsena kapele 'me re fumane hore na ho ja lijo tse ruileng tsa Coenzyme Q10/CoQ10 ho ka tsoela bakuli ba mofetše molemo kapa che.
Co-Q10 / Ubiquinol e sebelisoa ho bakuli ba kankere ea matsoele
Ts'ebeliso ea Co-Q10 / Ubiquinol e kanna ea ba le melemo ea ho fokotsa matšoao a ho ruruha ho bakuli ba mofets'e oa matsoele.
Ho 2019, phuputso e entsoe ke bafuputsi ba Univesithi ea Ahvaz Jundishapur ea Saense ea Bongaka Iran ho lekola litlamorao le melemo eo Co-enzyme Q10 (CoQ10) / ubiquinol supplementation e ka bang le eona ho bakuli ba mofets'e oa matsoele. Ho ruruha ho sa foleng ho tsejoa ho eketsa kholo ea hlahala. Kahoo, ba ile ba qala ho leka tšusumetso le molemo oa CoQ10 / ubiquinol supplementation ho li-marker tse ling tsa ho ruruha tse kang cytokines Interleukin-6 (IL6), Interleukin-8 (IL8) le factor vasot endothelial growth factor (VEGF) maling a bakuli ba 30 ba mofets'e oa mofets'e. ho amohela kalafo ea tamoxifen le lithuto tse 29 tse phetseng hantle. Sehlopha ka seng se arotsoe habeli ka sete e le 'ngoe ea bakuli ba mofets'e oa matsoele le lithuto tse phetseng hantle tse fumanang placebo' me sehlopha se seng se amohela 100 mg CoQ10 hang ka letsatsi likhoeli tse peli.
Phuputso e fumane hore tlatsetso ea CoQ10 e fokolitse li-serum tsa IL-8 le IL-6 empa eseng maemo a VEGF ha a bapisoa le placebo. (Zahrooni N et al, Ther Clin Risk Manag., 2019) Ho ipapisitsoe le sephetho sa sehlopha sena se senyenyane sa bakuli, tlatsetso ea CoQ10 e ka sebetsa hantle ho fokotsa maemo a ts'oaetso a cytokine, ka hona ea fokotsa litlamorao tsa ho ruruha ho bakoang ke bakuli ba mofets'e oa matsoele. .
Tšebeliso ea Co-Q10 / Ubiquinol e kanna ea ba le melemo ea ho ntlafatsa boleng ba bophelo ba bakuli ba mofets'e oa matsoele
Bakeng sa sehlopha sena sa bakuli ba nang le kankere ea matsoele ba 30 ba lilemo li 19-49 ba neng ba le kalafo ea Tamoxifen, ba arohane pakeng tsa lihlopha tse 2, e mong a nka 100 mg / letsatsi la CoQ10 ka likhoeli tse peli le sehlopha se seng sebakeng sa placebo, bafuputsi ba ile ba lekola phello ea boleng ba bophelo (QoL) ba bakuli ba mofets'e oa matsoele. Kamora ho sekaseka tlhaiso-leseling, bafuputsi ba fihletse qeto ea hore tlatsetso ea CoQ10 e na le phello e kholo maemong a 'mele, sechaba le kelellong ea basali ba nang le mofetše oa matsoele. (Hosseini SA et al, Psychol Res Behav Motsamaisi., 2020 ).
Ts'ebeliso ea Co-Q10 / Ubiquinol e kanna ea ba le melemo ea ho Ntlafatsa ho Pholoha ho bakuli ba nang le mofetše oa ho qetela.
Phuputso e entsoeng ke N Hertz le RE Lister ba tsoang Denmark ba hlahlobile ho pholoha ha bakuli ba 41 ba nang le mofetše oa ho qetela ba ileng ba fuoa li-supplement tsa coenzyme Q (10) le motsoako oa li-antioxidants tse ling tse kang vithamine C, selenium, folic acid le beta-carotene . Kankere ea mantlha ea bakuli bana e ne e le ka letsoeleng, bokong, matšoafo, liphio, manyeme, 'metso, mpa, kolone, tšoelesa ea senya, mae a bomme le letlalo. Phuputso e fumane hore pholoho ea sebele e bohareng e ne e le bolelele bo fetang ba 40% ho feta kamoo ho boletsoeng esale pele ho pholoha. (N Hertz le RE Lister, J Int Med Res., Nov-Dec)
Bafuputsi ba fihletse qeto ea hore tsamaiso ea Coenzyme Q10 le li-antioxidants tse ling e ka ba le melemo ea ho ntlafatsa pholo ea bakuli ba nang le mofetše oa ho qetela mme ba fana ka maikutlo a liteko tse kholo tsa kliniki bakeng sa ho netefatsa melemo ena.
Coenzyme Q10 / Ubiquinol e kanna ea ba le melemo ea ho fokotsa litlamorao tse bakoang ke Cardiotoxicity ho bana ba nang le Leukemia le Lymphoma
Phuputso e entsoeng ke bafuputsi ba Setsi sa Bongaka sa Bongaka sa Bongaka sa Bongaka, Univesithi ea 2 ea Naples naheng ea Italy e hlahlobile phello ea kalafo ea Coenzyme Q10 ho lefu la pelo ho bana ba 20 ba nang le Acute Lymphoblastic Leukemia kapa Non-Hodgkin Lymphoma e alafshoang ke Anthracyclines. Phuputso e fumane tšireletso ea Coenzyme Q10 mabapi le ts'ebetso ea pelo nakong ea kalafo le ANT ho bakuli bana. (D Iarussi et al, Mol Aspects Med., 1994)
Ho sebelisa Recombinant interferon alpha-2b le coenzyme Q10 e le kalafo ea kalafo ea adjuvant ea melanoma e ka fokotsa ho ipheta
Phuputso e entsoeng ke bafuputsi ba Univesithi ea K'hatholike ea Sacred Heart, Roma, Italy e ile ea hlahloba phello ea phekolo ea lilemo tsa 3 ka tekanyo e tlaase ea interferon alpha-2b le coenzyme Q10 ka ho khutla ka mor'a lilemo tse 5 ho bakuli ba nang le sethaleng sa I le II. melanoma (mofuta oa letlalo tsoaroa ke kankere) le diso tse tlositsweng ka ho buwa. (Luigi Rusciani et al, Melanoma Res., 2007)
Phuputso e fumane hore ts'ebeliso ea nako e telele ea lethal dose e ntlafalitsoeng ea interferon alpha-2b hammoho le coenzyme Q10 e fokolitse haholo sekhahla sa ho ipheta hape mme e bile le litlamorao tse mpe.
Mefuta e tlase ea Serum ea Coenzyme Q10 e kanna ea amahanngoa le Phekolo e Phahameng ea Ts'oaetso ho Kankere ea Sebete
Phuputsong e entsoeng ke bafuputsi ba Sepetlele sa Taichung Veterans General le Chung Shan Medical University, Taichung naheng ea Taiwan, ba ile ba lekola botsoalle pakeng tsa maemo a coenzyme Q10 le ho ruruha ho bakuli ba nang le hepatocellular carcinoma (mofetše oa sebete) kamora ho buuoa. Phuputso e fumane hore bakuli ba mofetše oa sebete ba na le maemo a tlase haholo a coenzyme Q10 le maemo a phahameng haholo a ho ruruha kamora ho buuoa. Kahoo, bafuputsi ba fihletse qeto ea hore coenzyme Q10 e kanna ea nkuoa e le kalafo ea antioxidant bakeng sa bakuli ba mofets'e ba sebete ba nang le ts'oaetso e phahameng ea ts'oaetso. (Hsiao-Tien Liu et al, Metsoako., 2017)
Maemo a tlase a Coenzyme Q10 a ka eketsa kotsi ea likankere tse ikhethileng
Phuputso e entsoeng ke bafuputsi ba tsoang Yuzuncu Yil University, Van naheng ea Turkey e fumane hore bakuli ba mofets'e ba matšoafo ba na le maemo a tlase haholo a Coenzyme Q10. (Ufuk Cobanoglu et al, Pele ea Cancer ea Pac Pac, 2011)
Phuputso e 'ngoe e entsoeng ke bafuputsi ba tsoang Univesithing ea Hawaii ho Manoa e lekotse botsoalle ba maemo a plasma CoQ10 le kotsi ea mofets'e oa matsoele, phuputsong ea taolo ea linyeoe ea basali ba China hara Study of Health ea Basali ba Shanghai (SWHS), mme ba fumana hore ba nang le boiphihlelo bo ikhethang. maemo a tlase a CoQ10 a ne a amahanngoa le kotsi e eketsehileng ea mofets'e oa matsoele. (Robert V Cooney et al, Kankere ea Epidemiol Biomarkers Prev., 2011)
fihlela qeto e
Tšusumetso ea boleng ba bophelo ke karolo ea bohlokoa ea lipatlisiso hobane e ama likarolo tsohle tsa bophelo ba bakuli. Batho ba bangata ba phonyohileng mofetše ba na le bophelo bo bobe 'me ba sebetsana le mathata a mokhathala, khatello ea maikutlo, migraine, maemo a ho ruruha joalo-joalo. Ho ja lijo tse nang le Coenzyme Q10/CoQ10/ubiquinol ho ka rua molemo ka ho susumetsa mokuli hore a be le oxidative metabolism, kahoo a fa mokuli matla a eketsehileng. boemo ba cellular. Liteko tse fapaneng tse nyane tsa kliniki li ile tsa lekola phello ea tlatsetso ea Coenzyme Q10 / CoQ10 / ubiquinol ho bakuli ba nang le mefuta e fapaneng ea kalafo. kankere. Ba fumane hore CoQ10/ubiquinol supplementation e na le melemo e ka bang teng mefuteng e fapaneng ea mofetše joalo ka mofetše oa matsoele, leukemia, lymphoma, melanoma le mofetše oa sebete. CoQ10 e bontšitse liphello tse ntle (melemo) ka ho fokotsa litekanyetso tsa matšoao a cytokine maling le ho ntlafatsa boleng ba bophelo ho bakuli ba kankere ea matsoele, ho fokotsa litla-morao tsa phekolo tse kang anthracycline-induced cardiotoxicity ho bana ba nang le kankere ea mali le lymphoma, ho fokotsa ho khutla hape. bakuli ba melanoma kapa ho ntlafatsa ho phela ho bakuli ba nang le mofetše oa ho qetela. Leha ho le joalo, liteko tse kholoanyane tsa kliniki lia hlokahala ho etsa qeto ea 'nete mabapi le katleho / melemo ea Coenzyme Q10/CoQ10/ubiquinol.
Lijo tseo u li jang le tse u tlatsetsang ke qeto eo u e etsang. Qeto ea hau e lokela ho kenyelletsa ho nahanisisa ka liphetoho tsa liphatsa tsa lefutso tsa mofetše, e leng mofetše, kalafo e tsoelang pele le litlatsetso, ho kula hohle, leseli la bophelo, boima, bolelele le litloaelo.
Morero oa phepo e nepahetseng bakeng sa mofets'e ho tsoa addon ha o ea ipapisa le lipatlisiso tsa inthanete. E iketsetsa liqeto bakeng sa hau e ipapisitse le mahlale a limolek'hule a kentsoeng tšebetsong ke bo-rasaense ba rona le lienjineri tsa software. Ho sa tsotelehe hore na o tsotella ho utloisisa metheo ea limolek'hule kapa che - bakeng sa moralo oa phepo ea mofets'e kutloisiso ea hlokahala.
Qala hona joale ka moralo oa hau oa phepo e nepahetseng ka ho araba lipotso lebitsong la mofetše, phetoho ea lefutso, kalafo e tsoelang pele le litlatsetso, ho kula hohle, litloaelo, mokhoa oa bophelo, sehlopha sa lilemo le bong.
Phepo e ikhethileng bakeng sa Kankere!
Kankere e fetoha ha nako e ntse e ea. Iketsetse 'me u fetole phepo ea hau ho latela sesupo sa mofets'e, kalafo, mokhoa oa bophelo, khetho ea lijo, lintho tse allergy le lintlha tse ling.
Bakuli ba mofets'e hangata ba tlameha ho sebetsana le tse fapaneng litla-morao tsa chemotherapy tse amang boleng ba bona ba bophelo le ho batla mekhoa e meng ea kalafo ea mofets'e. Ho nka phepo e nepahetseng le litlatsetso ho latela maikutlo a mahlale (ho qoba ho inahanela le ho khetha ka mokhoa o sa reroang) ke pheko ea tlholeho bakeng sa mofets'e le litla-morao tse amanang le kalafo