Muchidimbu
Radiation therapy inowanzo shandiswa kurapa gomarara rezamu, asi nguva zhinji maseru egomarara anogona kusawirirana neradiation therapy. Kudya/kushandiswa kweEllagic Acid kubva muzvokudya zvakaita sema berries, pomegranate uye walnuts (yakapfuma mune iyi phenolic compound) kana ma supplements ane zvakawanda zvingangobatsira pautano zvinosanganisira anti-cancer madhara. Ellagic acid zvakare inovandudza radiotherapy mhinduro mumasero egomarara rezamu panguva imwe chete iri redhiyo-inodzivirira kune akajairwa maseru: mushonga unogoneka wemazamu. kenza.
Chii chinonzi Ellagic Acid?
Ellagic Acid chinhu chinowanzoitika chinonzi polyphenol ine yakasimba antioxidant zvivakwa, inowanikwa mumichero yakawanda nemiriwo. Izvo zvakare zvinotengeswa zviripo nenzira yezvokudya zvinowedzera. Ellagic acid ine anti-kupisa uye anti-kuwanda mhedzisiro uye ine zvakawanda zvakanaka zvehutano.
Kudya Kwakapfuma muEllagic Acid: Ellagic acid inowanzo kuwanikwa muzvikafu zvakasiyana zvinosanganisira michero yakadai semazibheri, mahabhurosi, mabheribheri, cranberries uye matamba. Zvimwe zvekudya zvinosanganisira mamwe nzungu dzemuti senge walnuts uye pecans zvakare akapfuma muEllagic acid.
Hutano Makomborero eEllagic Acid
Zvimwe zvehutano zvinogona kubatsirwa neEllagic acid zvinowedzera zvinosanganisira anti-gomarara mhedzisiro, kudzikamisa zviratidzo zvechirwere chisingaperi chemetabolism kusanganisira dyslipidemia, kufutisa (nekushandisa ellagic acid kubva padamba redamba) uye kufutisa kwakanangana ne metabolic matambudziko akadai se insulin kuramba, mhando 2 chirwere cheshuga, uye isina-doro doro mafuta chiropa chirwere. (Inhae Kang et al, Adv Nutriti., 2016) Zvimwe zvehutano zvinobatsira zvekushandisa Ellagic Acid zvakare inosanganisira kukanganisa ganda kuunyana uye kuzvimba zvine chekuita nekusingaperi kweiyo UV kuratidzwa. (Ji-Muduku Bae et al, Exp Dermatol., 2010)
Radiotherapy yeCancer yeCancer
Kansa yepabonde ndiyo inonyanya kuzivikanwa kenza mumadzimai pasi rose (https://www.wcrf.org). Kubva munaNdira 2019, kune vakadzi vanopfuura mamirioni e3.1 vane nhoroondo yekenza yemazamu muUS chete, izvo zvinosanganisira vakadzi vari kuramba vachirapwa kana kupedzwa. (Statistics yeCancer yeCancer. https://www.breastcancer.org) Radiation therapy kana Radiotherapy imwe yenzira dze kenza kurapwa kunze kwekuvhiyiwa uye chemotherapy uye inoshandiswa nguva nenguva kurapa nhanho dzekutanga dzegomarara rezamu semushonga wenzvimbo mushure mekuvhiyiwa, kubatsira kudzikisa mukana wekuti kenza idzoke. Radiation therapy inoshandiswa zvakare kana gomarara radzoka uye richipararira kune dzimwe nhengo dzakaita seuropi nemabhonzo, pamwe chete nemamwe marapirwo akadai sechemotherapy kana immunotherapy.
Chikafu chekudya Mushure meKenza Kuongorora!
Hapana kanzura mbiri dzakafanana. Enda pamusoro peyakajairwa nhungamiro yemunhu wese uye utore sarudzo dzakagadzirirwa nezve chikafu uye zvinowedzerwa uine chivimbo.
Ellagic Acid uye Radiotherapy muCancer yeCancer
Radiation therapy inoshanda nekukonzera kukanganisa kuDNA ye kenza masero kuburikidza nepamusoro simba ionizing particles. Nekudaro, zvakare inokonzeresa kukuvadzwa kwechibatiso kune akatenderedza akajairwa, asiri ekenza maseru, zvichikonzera zvimwe zvisingadiwe uye zvakakomba mhedzisiro. Pamusoro pezvo, nekukurumidza kushanduka kwemaitiro emaseru egomarara, vanogara vachigadzirisa michina yavo yemukati uye vanokwanisa kupona neradiotherapy uye kuva kurwisa radiation. Kuvandudza mikana yekubudirira kweradiation therapy kwave nekutsvagisa kwakawanda pamakomisheni eradiosensitizer ayo kana akasanganiswa neradiation therapy inogona kubatsira kuwana kukuvara kukuru kwebundu ukuwo ichive radioprotective yeasiri-kenza maseru. Imwe yakadai yakasikwa komputa yakaedza kuratidza iyi mbiri pfuma yekuve radiosensitizer kumaseru egomarara rezamu uye radioprotective kumaseru akajairwa ndeye phenolic compound inonzi Ellagic Acid.
Zvidzidzo mumasero egomarara rezamu MCF-7 zvakaratidza kuti Ellagic Acid yakasanganiswa nemwaranzi inowedzera cancer cell kufa ne50-62% ukuwo musanganiswa mumwe chete waidzivirira mumasero akajairwa NIH3T3. Iyo nzira yakashandiswa neEllagic Acid kusimudzira kushanda kwemwaranzi pamasero egomarara rezamu yaive kuburikidza nekukanganisa mitochondria - mafekitori emagetsi emaseru; nekuwedzera pro cell-kufa; uye kuderedza zvinhu zvepro-kupona mu kenza sero. Ongororo dzakadai dzinoratidza kuti maumbirwo echisikigo akadai seEllagic Acid anogona kushandiswa “kuvandudza cancer radiotherapy nekuwedzera bundu toxicity uye kuderedza kukuvara kwesero kunokonzerwa neradiation.” (Ahire V. et al, Nutrition uye Cancer, 2017)
mhedziso
Pamusoro peiyo radiosensitization inokanganisa maseru ekenza, huwandu hwakawanda hwezvidzidzo zvesainzi hwakaratidzawo zvimwe zvakawanda zvinopesana nekenza zvimiro zveEllagic Acid (inowanzo kuwanikwa mumapomegranati), kubva mukukwanisa kumisa kuwanda kwemasero ekenza, kubatsira kukurudzira gomarara sero kufa kunonzi apoptosis, kudzivirira kupararira kwegomarara nekuvharira kukura kwemitsipa yeropa nyowani uye kutama nekupinda kwemasero egomarara kune mamwe mativi emuviri (Ceci C et al, Nutrients, 2018; Zhang H et al, Cancer Biol Med., 2014) Kune miedzo yekiriniki irikuenderera mberi mune dzakasiyana zviratidzo zvegomarara (gomarara rezamu (NCT03482401), colorectal cancer (NCT01916239), kenza yeprostate (NCT03535675) uye vamwe) kusimbisa chemopreventive uye kurapa mabhenefiti eEllagic Acid muvarwere vekenza, sezvinoonekwa mumhando dzekuyedza dze. kenza. Kunyangwe ichi chiwedzeredzo chechisikigo chisina chepfu uye chakachengeteka, Ellagic acid inofanirwa kungoshandiswa mukubvunzana nenyanzvi dzehutano, sezvo ichikwanisa kudyidzana nemimwe mishonga nekuda kwekuvharirwa kwezvinodhaka metabolizing enzymes muchiropa. Zvakare, kusarudza iyo chaiyo Ellagic acid yekuwedzera dosi uye kuumbwa kune yakagadziridzwa solubility uye bioavailability inodiwa kuti uwane iyo yakazara yekurapa maitiro.
Chikafu chipi chaunodya uye chinowedzera iwe kutora chisarudzo chaunoita. Sarudzo yako inofanirwa kusanganisira kutarisisa kwecancer genes shanduko, iyo kenza, kurapwa kuri kuenderera uye zvinowedzerana, chero mairigeji, ruzivo rwemararamiro, huremu, kukwirira uye maitiro.
Kurongeka kwehutano kwekenza kubva kuAddon hakubvi pakutsvaga kweinternet. Iyo inoshandura sarudzo kuitirwa iwe zvichibva pane samorekuru sainzi inoitwa nemasayendisiti edu uye mainjiniya esoftware. Zvisinei kuti une hanya here nekunzwisisa iyo yepasi biochemical molecular pathways kana kwete - yekuronga kudya kwemukenza kunzwisiswa kunodiwa.
Tanga IZVOZVO nekuronga kwako kudya kunovaka muviri nekupindura mibvunzo pazita rekenza, majini masayendisiti, kurapwa kuri kuenderera uye zvinowedzerana, chero kurwara, tsika, mararamiro, boka rezera uye murume kana murume.
Hunhu Hwakakosheswa Nekamwe Kenza!
Gomarara rinoshanduka nekufamba kwenguva. Gadzirisa uye gadzirisa chikafu chako zvichibva pachiratidzo chegomarara, marapirwo, mararamiro, zvaunofarira zvekudya, allergies uye zvimwe zvinhu.
Varwere veCancer kazhinji vanofanirwa kubata zvakasiyana chemotherapy mhedzisiro izvo zvinokanganisa kwavo hupenyu hwehupenyu uye kutarisa kune dzimwe nzira dzokurapa kenza. Kutora iyo kudya kwakakwana uye zvekuwedzera zvinoenderana nesainzi (Kudzivirira kufungidzira uye kusarudzika kusarudza) ndiyo yakanyanya kurongeka mushonga wekenza uye kurapwa kwakanangana nemhedzisiro.