Muchidimbu
Mbeu nhema nemafuta embeu nhema zvinogona kuderedza mhedzisiro yechemotherapy marapirwo emhando dzakasiyana dzegomarara. Mbeu nhema dzine zvakasiyana-siyana zvinoshanda zvinovaka muviri seThymoquinone. Iwo anticancer mabhenefiti embeu nhema uye Thymoquinone akaedzwa muvarwere uye zvidzidzo zverabhu. Mienzaniso mishoma yemabhenefiti e thymoquinone, sekuratidzwa kwezvidzidzo izvi zvinosanganisira kuderedzwa kwefivha uye kutapukira kubva kuderera neutrophil kuverenga mukenza dzepfungwa dzevana, yakaderedzwa methotrexate (chemotherapy) inoenderana nemhedzisiro yehupfu muleukemia uye mhinduro iri nani muvarwere vekenza yemazamu vanobatwa netamoxifen. kurapwa. Nokuti mafuta emafuta madema anovava - anowanzotorwa neuchi. Kubva pane izvo kenza uye kurapwa, zvimwe zvekudya uye zvinovaka muviri zvinogona kunge zvisina kuchengeteka. Saka, kana murwere wegomarara rezamu ari kurapwa netamoxifen uye achidya mafuta embeu nhema - saka zvakakosha kudzivirira Parsley, Sipinachi uye Green Tea, uye chikafu chekuwedzera seQuercetin. Nekudaro, zvinonyanya kukosha kugadzirisa hutano kune chaiyo cancer uye kurapwa kuti uwane mabhenefiti kubva kune zvinovaka muviri uye kuve wakachengeteka.
Vaya chete vanobatwa nechirwere chegomarara chisingatarisirwi uye vadikani vavo vanonyatsoziva kupengereka kwazvinoita kuyedza kufunga nzira iri pamberi, mukuona vanachiremba vepamusoro, nzira dzekurapa dzepamusoro, uye chero imwe mararamiro, chikafu uye dzimwe sarudzo. vanogona kushandisa, kuti vawane mukana wekurwa wekusave nekenza. Zvakare, vazhinji vakaremerwa nemishonga yechemotherapy yavanozofanira kuita kunyangwe yakaomesesa-mhedzisiro uye vanotsvaga nzira dzekusimudzira chemotherapy yavo nemasikirwo ekuwedzera sarudzo kudzikamisa mhedzisiro uye kugadzirisa hutano hwavo. Imwe yemasikirwo ekuwedzera ane yakakwana preclinical data mukati kenza sero mitsara uye mhuka mhando mafuta nhema mbeu.
Nhema Mbeu Mafuta uye Thymoquinone
Mbeu nhema mafuta inowanikwa kubva kune nhema mbeu, mhodzi yemuti unonzi Nigella sativa ine ruvara rwepepuru, bhuruu kana chena maruva, anowanzozivikanwa se fennel maruva. Mbeu nhema dzinowanzo shandiswa muAsia neMediterranean chikafu. Mbeu nhema dzinozivikanwa zvakare sekuti nhema kumini, kalonji, nhema caraway uye nhema nhema hanyanisi.
Mbeu nhema dzakashandiswa kugadzira mishonga kwezviuru zvemakore. Imwe yeakakosha bioactive zvinoshandiswa zvembeu nhema mafuta ine antioxidant, anti-kupisa uye anti-kenza zvivakwa ndiThymoquinone.
General Hutano Kubatsirwa kweMutema Mbeu Oiri / Thymoquinone
Nekuda kweayo antioxidant uye inorwisa-kuzvimba zvinhu, Nhema mbeu mafuta / Thymoquinone inoonekwa seine zvakawanda zvehutano zvinobatsira. Mimwe yemamiriro ezvinhu angave anokwanisa mbeu yembeu nhema ndeaya:
- Asthma: Mbeu nhema inogona kudzora kukosora, kufema, uye kushanda kwemapapu kune vamwe vanhu vane asthma.
- Diabetes: Mbeu nhema inogona kusimudzira mashuga eropa uye cholesterol muzvikamu zvevanhu vane chirwere cheshuga.
- High blood pressure: Kutora mbeu nhema kunogona kudzikamisa kukwira kweropa nemari shoma.
- Kusabereka kwemurume: Kutora mafuta embeu nhema kunogona kuwedzera huwandu hwehurume uye nekukurumidza kuti vanofamba sei nevarume vasina mbereko.
- Kurwadziwa kwepabonde (mastalgia): Kuisa gel rine mafuta embeu nhema kumazamu panguva yekuenda kumwedzi kunogona kudzikamisa marwadzo kuvakadzi vane kurwadziwa nemuzamu.
Side-Mhedzisiro YeMutema Mbeu Oiri / Thymoquinone
Kana ikadyiwa muzvishoma seshonga mukudya, mbeu nhema nemafuta embeu nhema zvinogona kunge zvakachengeteka kuvanhu vazhinji. Nekudaro, kushandisa nhema mbeu yemafuta kana zvinowedzerwa mune zvinotevera mamiriro zvinogona kunge zvisina kuchengetedzeka.
- Kubata: Dzivisa kuwanda kwemafuta embeu nhema kana zvekutora panguva yekuzvitakura nekuti zvinogona kudzora chibereko kubva pakubatira.
- Kushungurudza Kubuda ropa: Mbeu nhema yemafuta inodya inogona kukanganisa kuvhara ropa uye kuwedzera njodzi yekubuda ropa. Nekudaro, pane mukana wekuti kudyiwa kwembeu nhema kunogona kuita kuti matambudziko ekubuda ropa awedzere.
- Hypoglycemia: Sezvo mbeu nhema yemafuta inogona kudzikisa mashuga eropa, varwere vane chirwere cheshuga vari kutora mishonga vanofanirwa kutarisa zviratidzo zveshuga muropa.
- Kuderera kweropa: Dzivisa mafuta embeu nhema kana uine yakaderera BP sezvo mbeu nhema inogona kudzikisa kuwedzera kweropa mberi.
Nekuda kweidzi njodzi dzinogona kuitika uye mhedzisiro, munhu anofanirwa kudzivirira kushandisa mafuta embeu nhema kana akarongerwa kuvhiya.
Chikafu chekudya Mushure meKenza Kuongorora!
Hapana kanzura mbiri dzakafanana. Enda pamusoro peyakajairwa nhungamiro yemunhu wese uye utore sarudzo dzakagadzirirwa nezve chikafu uye zvinowedzerwa uine chivimbo.
Thymoquinone / Nhema Mbeu Oiri Kushandisa yekuvandudza Chemotherapy Kubudirira kana Kuderedza Maseru-Mhedzisiro muCancer
Ongororo dzichangoburwa muvezera rakaongorora magazini esainzi akapfupikisa huwandu hwakawanda hwekuyedza pamasero kana mhando dzemhuka dzekenza dzakasiyana dzakaratidza akawanda anticancer zvivakwa zveThymoquinone kubva kuBlack mbeu yemafuta, kusanganisira nemabatiro aingaita kukurudzira mamota kune mamwe akajairwa chemotherapy uye radiation kurapwa (Mostafa AGM et al, Front Pharmacol, 2017; Khan MA et al, Oncotarget 2017).
Nekudaro, pane chete tsvakurudzo shoma uye zvidzidzo muvanhu zviripo izvo zvakaongorora mhedzisiro ye thymoquinone kana nhema mhodzi yemafuta mune zvakasiyana. kanzira kana ichirapwa kana pasina chaiyo chemotherapies. Nekenza dzakawanda, chemotherapy kana radiation therapy inopihwa mushure mekuvhiyiwa kubvisa chero asara maseru egomarara. Asi aya adjuvant kurapa haawanzo kubudirira uye anogona kukanganisa hupenyu hwemurwere. Mune ino blog, isu tichaongorora akasiyana ekiriniki zvidzidzo zvemafuta nhema mbeu kana thymoquinone mugomarara uye toona kana kushandiswa kwayo kunobatsira varwere vegomarara uye kunogona kushandiswa kukwirisa. kanzuru yevarwere chikafu.
Mbeu Dema / Thymoquinone pamwe neChemotherapy inogona Kuderedza Iyo Side-Mhedzisiro yeFebrile Neutropenia muVana vane Brain Tumors.
Chii chinonzi Febrile Neutropenia?
Imwe yemhedzisiro-mhedzisiro yekemotherapy kurapwa kudzvanywa kwemongo wemapfupa uye maseru ekudzivirira. Febrile neutropenia mamiriro apo nekuda kwenhamba shoma kwazvo yemautrophil, mhando yemasero machena eropa mumuviri, murwere anogona kukura hutachiona nefivha. Ichi chinowanzoitika-chikamu chinoonekwa muvana vane mamota europi avo vari kurapwa chemotherapy.
Kudzidza uye Kutsvaga Kwakakosha
Mune ongororo yekiriniki yakasarudzika, yakaitwa kuAlexandria University kuEjipitori, vaongorori vakaongorora mhedzisiro yekutora mbeu nhema nekemotherapy, padivi-mhedzisiro yefebrile neutropenia muvana vane mamota europi. Vana makumi masere vari pakati pemazera e80-2 makore vane mamota europi, vachirapwa chemotherapy, vakapiwa kumapoka maviri. Rimwe boka revana makumi mana rakagamuchira 18 g yembeu nhema zuva nezuva mukati mekurapwa kwavo kwemakemotherapy apo rimwe boka revana makumi mana rakagamuchira chemotherapy. (Mousa HFM et al., Yevana Yekutya Syst., 2017).
Mhedzisiro yenyaya iyi yakaratidza kuti chete 2.2% yevana vari muboka vanotora mhodzi nhema vaive nefebrile neutropenia vachiri muboka rinodzora, 19.2% vana vaive nefebrile neutropenia mhedzisiro. Izvi zvinoreva kuti kudyiwa kwembeu nhema pamwe nekemotherapy kwakadzora zviitiko zvefebrile neutropenia episodes ne88% zvichienzaniswa neboka rinodzora.
Nhema Mbeu Oiri / Thymoquinone inogona Kuderedza Methotrexate Chemotherapy-inokonzeresa Side-Mhedzisiro yeRopa / Hepato-huturu muvana vane Leukemia
Acute lymphoblastic leukemia ndeimwe yekenza dzevacheche dzinowanzozivikanwa. Methotrexate inowanzoitwa chemotherapy inoshandiswa kuwedzera mwero wekupona muvana vane leukemia. Nekudaro, kurapwa kwemethotrexate kunogona kukonzera kwakakomba chemotherapy mhedzisiro-mhedzisiro yehepatotoxicity kana chiropa chepfu, zvichidaro kudzikisira kukanganisa kwayo.
Kudzidza & Key Zviwanikwa
A kutongwa kwakaitwa nemaitiro kwakaitwa nevatsvagiri kubva kuYunivhesiti yeTanta kuEjipitori kwakayedza kurapa kweBlack mbeu yemafuta pane methotrexate yakakonzera hepatotoxicity muvana makumi mana veEjipitori vakawanikwa vaine acute lymphoblastic leukemia. Hafu yevarwere yaibatwa nemethotrexate therapy uye Nhema mbeu mafuta uye zororo hafu yakarapwa ne methotrexate therapy uye placebo (chinhu chisina kukosha kwekurapa). Chidzidzo ichi chaisanganisira vana makumi maviri vane hutano hwakaenzana nezera uye bonde uye vakashandiswa seboka rinodzora. (Adel A Hagag et al, Infect Disord Zvinodhaka Zvinangwa., 40)
Chidzidzo ichi chakawana kuti nhema mbeu yemafuta / thymoquinone yakadzora methotrexate chemotherapy inokonzeresa divi-mhedzisiro yehepatotoxicity uye yakawedzera muzana yevarwere vanowana kuregererwa kwakazara neinenge 30%, kudzikisira kudzokerazve neinenge 33%, uye nekuvandudza kupona-kusarwara kwezvirwere neinenge 60% zvichienzaniswa ne placebo muvana vane acute lymphoblastic leukemia; zvisinei, pakanga pasina kuvandudzwa kwakakosha muhupenyu hwese. Vatsvakurudzi vakagumisa kuti mbeu nhema mafuta / thymoquinone inogona kukurudzirwa semushonga unobatsira mune vana vane Leukemia vachirapwa methotrexate.
Kutora Thymoquinone pamwe neTamoxifen kunogona Kuvandudza Kushanda kwayo muVarwere veCancer yeCancer
Gomarara repazamu nderimwe reakawanda kanzira muvanhukadzi munyika yose. Tamoxifen ndiyo chiyero chekutarisira hormonal therapy inoshandiswa muestrogen receptor positive (ER+ve) kenza yemazamu. Zvisinei, kukura kwetamoxifen kuramba ndeimwe yezvipingamupinyi zvikuru. Thymoquinone, chinhu kiyi chinoshanda chemafuta embeu nhema, yakawanikwa iine cytotoxic mumhando dzinoverengeka dzemishonga inodzivirira kenza yemunhu.
Kudzidza uye Kutsvaga Kwakakosha
Mune ongororo yakaitwa nevatsvagiri kubva kuCentral University yeGujarat kuIndia, Tanta University kuEgypt, Taif University muSaudi Arabia neBenha University kuEjipitori, vakaongorora mashandisiro ekushandisa thymoquinone (chinhu chakakosha chemafuta embeu nhema) pamwe ne tamoxifen mune varwere vane kenza yemazamu. Chidzidzo ichi chaisanganisira vanosvika makumi masere evarwere vechikadzi vane gomarara repazamu avo vasina kurapwa, kurapwa netamoxifen chete, kurapwa ne thymoquinone (kubva pambeu nhema) chete kana kurapwa neese thymoquinone uye tamoxifen. (Ahmed M Kabel et al, J Unogona Sci Res., 80)
Chidzidzo chacho chakawana kuti kutora thymoquinone pamwe neTamoxifen kwakave nemhedzisiro iri nani pane yega yemishonga iyi yega kune varwere vane gomarara repazamu. Vatsvakurudzi vakagumisa kuti kuwedzerwa kwe thymoquinone (kubva kune yakasviba mbeu yemafuta) kune tamoxifen kunogona kumiririra nzira nyowani yekurapa yevatarisiri vegomarara repazamu.
Thymoquinone inogona kunge yakachengeteka kune Varwere vane Advanced Refractory Cancers, asi inogona kunge isina Therapeutic Impact
Kudzidza uye Kutsvaga Kwakakosha
Muchikamu chandakafunda chakaitwa muna2009, nevatsvagiri veKing Fahd Hospital yeUniversity uye King Faisal University muSaudi Arabia, vakaongorora kuchengetedzeka, huturu uye kurapwa kwehutachiona hwe thymoquinone mune varwere vane gomarara repamberi iro pakanga pasina mushonga unorapa. kana matanho ekunyaradza. Muchidzidzo ichi, varwere vakuru makumi maviri nevaviri vane mamota akasimba kana hematological malignancies avo vakakundikana kana kudzokazve kubva pakurapa kwakajairwa vakapihwa thymoquinone nemuromo padanho rekutanga reiyo 21, 3, kana 7mg / kg / zuva. Mushure mevhareji yenguva yenguva ye10 mavhiki, hapana mhedzisiro yakataurwa. Zvisinei, hapana zvinopesana nekenza zvakaonekwa zvakare muchidzidzo ichi. Kubva pane ongororo iyi vaongorori vakagumisa kuti thymoquinone yaibvumidzwa mushe kubva padanho re3.71mg / zuva kusvika 75mg / zuva isina huturu kana mhinduro dzekurapa dzakataurwa. (Ali M. Al-Amri naAbdullah O. Bamosa, Shiraz E-Med J., 2600)
mhedziso
Zvidzidzo zvakawanda zvepreclinical pamasero mitsara uye akasiyana kenza mamodheru masisitimu akambowana akawanda anticancer zvimiro zveThymoquinone kubva kune nhema mhodzi mafuta. Zvidzidzo zvishoma zvekiriniki zvakaratidzawo kuti kunwa kwemafuta embeu nhema/thymoquinone kunogona kuderedza chemotherapy induced side-effect yefebrile neutropenia muvana vane mazamu europi, Methotrexate inokonzera chiropa chepfu muvana vane leukemia uye inogona kuvandudza mhinduro kune tamoxifen kurapa mune varwere vekenza yemazamu. . Nekudaro, mafuta embeu nhema anowedzera kana thymoquinone anowedzera anofanirwa kutorwa sechikamu chekudya chete mushure mekubvunzana nemutarisiri wako wehutano kuti udzivise kupindirana kupi nekupi kwakashata nekuramba kuchirapa uye mhedzisiro nekuda kwemamwe mamiriro ehutano.
Chikafu chipi chaunodya uye chinowedzera iwe kutora chisarudzo chaunoita. Sarudzo yako inofanirwa kusanganisira kutarisisa kwecancer genes shanduko, iyo kenza, kurapwa kuri kuenderera uye zvinowedzerana, chero mairigeji, ruzivo rwemararamiro, huremu, kukwirira uye maitiro.
Kurongeka kwehutano kwekenza kubva kuAddon hakubvi pakutsvaga kweinternet. Iyo inoshandura sarudzo kuitirwa iwe zvichibva pane samorekuru sainzi inoitwa nemasayendisiti edu uye mainjiniya esoftware. Zvisinei kuti une hanya here nekunzwisisa iyo yepasi biochemical molecular pathways kana kwete - yekuronga kudya kwemukenza kunzwisiswa kunodiwa.
Tanga IZVOZVO nekuronga kwako kudya kunovaka muviri nekupindura mibvunzo pazita rekenza, majini masayendisiti, kurapwa kuri kuenderera uye zvinowedzerana, chero kurwara, tsika, mararamiro, boka rezera uye murume kana murume.
Hunhu Hwakakosheswa Nekamwe Kenza!
Gomarara rinoshanduka nekufamba kwenguva. Gadzirisa uye gadzirisa chikafu chako zvichibva pachiratidzo chegomarara, marapirwo, mararamiro, zvaunofarira zvekudya, allergies uye zvimwe zvinhu.
Varwere veCancer kazhinji vanofanirwa kubata zvakasiyana chemotherapy mhedzisiro izvo zvinokanganisa kwavo hupenyu hwehupenyu uye kutarisa kune dzimwe nzira dzokurapa kenza. Kutora iyo kudya kwakakwana uye zvekuwedzera zvinoenderana nesainzi (Kudzivirira kufungidzira uye kusarudzika kusarudza) ndiyo yakanyanya kurongeka mushonga wekenza uye kurapwa kwakanangana nemhedzisiro.