Mfundo
Zakudya zopatsa thanzi monga Black Pepper zili ndi maubwino ambiri azaumoyo ndipo zikugwiritsidwa ntchito kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Koma, kodi ndizotetezeka kumwa zowonjezera za Black Pepper zamitundu yonse ya khansa osaganizira za chithandizo chilichonse chomwe akupitilabe komanso njira zina zamoyo? Chikhulupiriro chofala koma chongopeka ndichakuti chilichonse chachilengedwe chingangondipindulitsa kapena kusandipweteka. Monga chitsanzo chimodzi, kugwiritsa ntchito zipatso za manyumwa ndi mankhwala ena sikuvomerezeka. Chitsanzo china, kugwiritsa ntchito sipinachi ndi mankhwala ochepetsa magazi kumatha kuyambitsa mavuto ndipo kuyenera kupewedwa. Khansa, zakudya zomwe zimaphatikizira chakudya ndi zowonjezera zowonjezera zawonetsedwa kuti zimakhudza zotsatira. Chifukwa chake funso lofunsidwa kawirikawiri ndi odwala khansa kwa akatswiri azamankhwala ndi madotolo ndi "Ndiyenera Kudya Chiyani Ndipo Ndiyenera Kupewa Chiyani?".
Kutenga zakudya zowonjezera zakudya za Black Pepper kungathandize odwala khansa omwe ali ndi Primary Central Nervous System Lymphoma (PCNSL) pa chithandizo cha Epirubicin. Koma pewani zowonjezera Pepper ngati pa Paclitaxel chithandizo cha Adenoid Cystic/Adenocystic Carcinoma. Mofananamo, kutenga zakudya zowonjezera zakudya za Black Pepper kumatha kupindulitsa anthu athanzi omwe ali pachiwopsezo cha majini khansa chifukwa cha kusintha kwa jini SDHAF2. Koma pewani kudya zakudya zowonjezera tsabola wakuda mukakhala pachiwopsezo cha khansa chifukwa cha kusintha kwa gene TERT.
Kutenga - malingaliro anu payekha angakhudze chisankho chanu ngati chowonjezera chakuthupi cha Black Pepper chili bwino kapena ayi. Komanso kuti lingaliro ili lifunika kuwunikiridwa pafupipafupi momwe zinthu zimasinthira. Zinthu monga mtundu wa khansa, mankhwala omwe alipo pakadali pano ndi zowonjezera, zaka, jenda, kulemera, kutalika, moyo komanso kusintha kwa majini. Chifukwa chake funso lovomerezeka lomwe mungafunse kuti mulandireko chakudya ndi zowonjezera zachilengedwe ndi momwe zimakhudzira zomwe mumakonda.
Mwachidule
Zakudya zowonjezera mavitamini - mavitamini, zitsamba, mchere, maantibiotiki, ndi mitundu ina yapaderadera ikukula. Zowonjezera ndizowonjezera zazambiri zomwe zimapezekanso muzakudya zosiyanasiyana. Kusiyanitsa kukhala zakudya kumakhala ndi zinthu zopitilira chimodzi pazomwe zimasakanikirana pang'ono. Kumbukirani kuti chilichonse mwazipanganazi chili ndi sayansi yake komanso makina ake am'magulu - chifukwa chake sankhani kuphatikiza kwa zowonjezera monga Black Pepper kutengera momwe zinthu zilili.
Ndiye funso ndilakuti muyenera kumwa Pepper wakuda? Kodi muyenera kuzitenga mukakhala pachiwopsezo cha khansa pakusintha kwa gene TERT? Muyenera kumwa pamene chibadwa chiopsezo cha khansa kusintha kwa jini SDHAF2? Kodi muyenera kumwa mukapezeka ndi Adenoid Cystic/Adenocystic Carcinoma? Kodi muyenera kumwa Black Pepper supplement mukapezeka ndi Primary Central Nervous System Lymphoma (PCNSL)? Kodi muyenera kumwa mukamamwa mankhwala a Paclitaxel? Kodi muyenera kupitiriza kumwa ngati mutasintha mankhwala anu kuchoka pa Paclitaxel kukhala Epirubicin? Chifukwa chake kufotokozera mwachidule monga - mwachilengedwe kapena kumawonjezera chitetezo chokwanira sikungakhale kovomerezeka komanso kokwanira posankha Black Pepper.
Cancer
Khansa imakhalabe vuto losathetsedwa. Kupezeka kwabwino kwa chithandizo chamankhwala komanso kuwunika kwa khansa kudzera m'magazi ndi malovu zakhala zofunikira pakuwongolera zotsatira. Kulowererapo koyambirira - kumawongolera zotsatira zake. Kuyesedwa kwa majini kumatha kuyesa kuwopsa kwa khansa komanso kutengeka msanga. Koma kupatula kuwunika pafupipafupi nthawi zambiri palibe njira zochiritsira zomwe zingachitike. Pambuyo pozindikira kuti ali ndi khansa monga Adenoid Cystic Carcinoma kapena Primary Central Nervous System Lymphoma, mankhwalawa amadzipangira okha kukhala ndi zotupa zamatenda komanso zinthu monga matenda, zaka komanso jenda. Pakati pa kukhululukidwa kwa khansa (pambuyo poti mankhwala atha kumaliza) - kuwunika kumagwiritsidwa ntchito poyesa kubwereranso kulikonse ndikusankha njira zotsatirazi. Odwala khansa ambiri komanso omwe ali pachiwopsezo amatenga zowonjezera zowonjezera monga Black Pepper.
Ndiye funso ndiloti kodi mavuto onse amtundu wa khansa ndi mitundu ina ya khansa yomwe ingaganizidwe ngati imodzi posankha kugwiritsa ntchito Pepper Wakuda? Kodi njira ya biochemical yomwe imakhudzanso chiopsezo cha chibadwa cha khansa chifukwa cha kusintha kwa majini TERT ndi yofanana ndi kusintha kwa majini SDHAF2? Kodi tanthauzo lakutenga Tsabola Wakuda kwa Adenoid Cystic Carcinoma chimodzimodzi ndi Primary Central Nervous System Lymphoma (PCNSL)? Kodi ndi chimodzimodzi ngati mukumwa mankhwala a Paclitaxel kapena Epirubicin?
Pepper Wakuda - Chowonjezera Chakudya
Black Pepper, wotchedwanso Piper Nigrum, ndi wa banja la Piperaceae. Chipatso cha Black Pepper chimadziwikanso kuti peppercorn chomwe chimauma ndikugwiritsidwa ntchito ngati zonunkhira. Zina mwazabwino zakudya tsabola wakuda ndi izi: (Murlidhar Meghwal et al, Phytother Res., 2013)
- Wolemera ndi antioxidant
- Ali ndi mphamvu yotsutsa-yotupa
- Ali ndi chitetezo cha mthupi
- Kuchulukitsa mayamwidwe ndi kupezeka kwa mankhwala ndi zitsamba mkati mwa thupi.
- Amachepetsa mphumu
- Amachepetsa cholesterol (Gabriel A Agbor ku al, Chakudya Chem., 2012)
- Amazilamulira shuga (Chetna Kharbanda ku al, Chem Biol Mankhwala Osokoneza Bongo. 2016)
- Ali ndi katundu wa khansa (Azadeh Manayi et al, Curr Med Chem, 2018)
Mavitamini a Black Pepper ali ndi zinthu zambiri zothandiza kuphatikiza Piperine, Retinol, Vitamini C ndi Folic Acid m'magulu osiyanasiyana. Njira zama cell zomwe zimayendetsedwa ndi Black Pepper zimaphatikizira Focal Adhesion, Cell Cycle, Nucleotide metabolism, Stem Cell Signaling ndi NFKB Signaling. Njira zamaguluzi zimayendetsa mwachindunji kapena m'njira zina mayendedwe am'magazi am'mimba monga kukula, kufalikira ndi kufa. Chifukwa cha lamuloli - pakudya zakudya zabwino za khansa, kusankha koyenera kwa zowonjezera monga Black Pepper payekha kapena kuphatikiza ndichofunikira kupanga. Mukamapanga zisankho pakugwiritsa ntchito chowonjezera cha Black Pepper cha khansa - ganizirani izi ndi mafotokozedwe onse. Chifukwa monga momwe zimakhalira ndi khansa - Kugwiritsa ntchito Pepper Wakuda sikungakhale kusankha kwakukulu pamitundu yonse ya khansa.
Kusankha Zowonjezera Zakudya Zam'mimba pa Khansa Yanu
Chifukwa chomwe palibe njira yosavuta yoyankhira funso "Kodi ndiyenera kupewa liti Tsabola Wakuda Khansa" ndichifukwa "Zimadalira!". Monga momwe chithandizo chimodzimodzi sichigwira ntchito kwa wodwala khansa aliyense, kutengera momwe inu mukuonera kuti Black Pepper ikhoza kukhala yowopsa kapena yotetezeka. Pamodzi ndi khansa komanso ma genetiki omwe amagwirizana nawo - mankhwala omwe akupitilizidwa, zowonjezera mavitamini, zizolowezi za moyo, BMI ndi ziwengo zonse ndizomwe zimasankha ngati Pepper wakuda ayenera kupewedwa kapena ayi ndipo chifukwa chiyani.
1. Kodi Black Pepper Supplements idzapindulitsa Odwala a Khansa omwe ali ndi Adenoid Cystic / Adenocystic Carcinoma akulandira chithandizo cha Paclitaxel?
Adenoid Cystic / Adenocystic Carcinoma amadziwika ndi kuyendetsedwa ndi masinthidwe enieni amtundu monga NFIB ndi MYB zomwe zimatsogolera ku kusintha kwa biochemical pathway mu Focal Adhesion, PI3K-AKT-MTOR Signaling, Notch Signaling ndi Cholesterol Metabolism. Chithandizo cha khansa ngati Paclitaxel chimagwira ntchito mwanjira inayake. Cholinga chake ndikukhala ndi kulumikizana kwabwino pakati pa chithandizo chamankhwala ndi njira zoyendetsera khansa panjira yamunthu yomwe ili yothandiza. Zikatero, chakudya chilichonse kapena chowonjezera chopatsa thanzi chomwe chili ndi zotsatira zotsutsana ndi mankhwalawa kapena kuchepetsa kuphatikizika kuyenera kupewedwa. Mwachitsanzo, Black Pepper supplement iyenera kupewedwa chifukwa cha Adenoid Cystic/Adenocystic Carcinoma pamodzi ndi chithandizo cha Paclitaxel. Black Pepper supplement imakhudza njira/njira monga Focal Adhesion yomwe imalimbikitsa oyendetsa adenoid Cystic/Adenocystic Carcinoma ndi/kapena kulepheretsa chithandizo. Kuphatikiza apo, zowonjezera tsabola wakuda zili ndi zosakaniza zogwira ntchito monga Piperine yomwe ili ndi CYP2C8 ndi CYP3A4 yolumikizana ndi chithandizo cha Paclitaxel, motero ziyenera kupewedwa. (Pius S. Fasinu et al. Kutsogolo Oncol., 2019; Chakudya ndi Mankhwala Osokoneza Bongo, Mhaske et al., Pharm Anal Acta, 2018Zina mwa zinthu zomwe ziyenera kuganiziridwa posankha zakudya ndi mtundu wa khansa, mankhwala ndi zowonjezera zomwe zikugwiritsidwa ntchito pakadali pano (ngati zilipo), zaka, jenda, BMI, moyo komanso chidziwitso chilichonse chokhudza kusintha kwa majini (ngati alipo).
2. Kodi Black Pepper Supplements ingapindulitse Cancer Patients Primary Central Nervous System Lymphoma (PCNSL) yochiritsidwa ndi Epirubicin Treatment?
Primary Central Nervous System Lymphoma (PCNSL) imadziwika ndi kuyendetsedwa ndi masinthidwe enieni a majini monga MYD88 ndi CD79B zomwe zimatsogolera ku kusintha kwa biochemical pathway mu Cell Cycle, NFKB Signaling, Apoptosis, B Cell Receptor Signaling ndi RAS-RAF Signaling. Chithandizo cha khansa monga Epirubicin chimagwira ntchito m'njira zinazake. Cholinga chake ndi kukhala ndi kulumikizana kwabwino pakati pa chithandizo ndi njira zoyendetsera khansa panjira yokhazikika. Zikatero, chakudya chilichonse kapena chowonjezera chopatsa thanzi chomwe chimagwirizana ndi chithandizo kapena kuchepetsa kuphatikizika chiyenera kuganiziridwa. Mwachitsanzo, Black Pepper supplement iyenera kuganiziridwa pa Primary Central Nervous System Lymphoma (PCNSL) pamodzi ndi chithandizo cha Epirubicin. Black Pepper supplement imakhudza njira/njira monga Cell Cycle ndi NFKB Signaling zomwe zimalepheretsa madalaivala a Primary Central Nervous System Lymphoma (PCNSL) ndi/kapena kupititsa patsogolo chithandizo.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
3. Kodi Zakudya Zam'madzi Zakuda Zimakhala Zosungika Kwa Anthu Amathanzi Okhala Ndi Chiwopsezo Chokhala Ndi TERT?
Makampani osiyanasiyana amapereka magulu amtundu kuti ayesedwe kuti awone ngati ali ndi khansa zosiyanasiyana. Izi zimaphimba majini omwe amapezeka ndi khansa ya m'mawere, ovary, chiberekero, prostate, m'mimba ndi ena. Kuyesedwa kwa majini amtunduwu kumatha kutsimikizira kuti munthu ali ndi matendawa ndikuthandizira kuwongolera chithandizo cha kasamalidwe. Kuzindikiritsa zomwe zimayambitsa matenda kungathandizenso kuyesa ndi kuzindikira abale omwe ali pachiwopsezo.
TERT ndi imodzi mwamajini omwe amapezeka nthawi zambiri m'magulu oyesa kuopsa kwa khansa. Kusintha kwa TERT kumayambitsa njira zama biochemical Nucleotide metabolism, MAPK Signaling, Stem Cell Signaling, Hypoxia ndi RUNX Signaling kuti ikhudzidwe. Njira izi ndi zoyendetsa mwachindunji kapena zosalunjika khansa mapeto a maselo. Tsabola Wakuda sayenera kupewedwa pamene gulu la majini likuwonetsa kusintha kwa TERT kwa Khansa ya Hematological. Black Pepper supplement imakhudza njira / njira monga Nucleotide metabolism ndi MAPK Signaling ndipo imapanga zotsatira zoipa ndi TERT ndi zina zokhudzana nazo.
4. Kodi Zakudya Zam'madzi Zakuda Zimakhala Zosungika Kwa Anthu Amathanzi Okhala Ndi Chiwopsezo Chosokonekera cha SDHAF2?
SDHAF2 ndi imodzi mwazomwe zimapezeka m'magulu oyeserera kuyesa khansa. Kusintha kwa SDHAF2 kumayambitsa njira zamagetsi za Stem Cell Signaling, Hypoxia, Carbohydrate Metabolism, Signature ya MAPK ndi Angiogenesis kuti zikhudzidwe. Njirazi ndi zoyendetsa molunjika kapena zosawonekera zamagulu am'mapeto am'mimba mwa khansa. Ganizirani kutenga chowonjezera cha Black Pepper pomwe majini azindikiritsa kusintha kwa SDHAF2 kwa Khansa ya Chithokomiro ndi Khansa ya Neuroendocrine. Black Pepper imakhudza njira / njira monga Stem Cell Signaling ndi Hypoxia ndipo zimathandizira omwe ali ndi SDHAF2 ndi zina zokhudzana nazo.
* Zinthu Zina zimaphatikizidwanso ngati BMI, Kuchiza, Zizolowezi Zaumoyo
Pomaliza
Zinthu ziwiri zofunika kwambiri kukumbukira ndi izi khansa mankhwala ndi zakudya sizili zofanana kwa aliyense. Zakudya zopatsa thanzi zomwe zimaphatikizapo zakudya ndi zakudya zopatsa thanzi monga Black Pepper, ndi chida chothandiza chomwe mutha kuwongolera mukakumana ndi khansa.
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.