Mfundo
Kufotokozera zamayesero azachipatala a mankhwala a cytotoxic chemotherapy kumachepetsa kuwopsa ndi poizoni wa mankhwalawa kudzera m'mafotokozedwe okhwima komanso osocheretsa. Kafukufuku yemwe mankhwalawa adanenedwa kuti amalekerera adalengeza kuti oposa theka la odwalawo adasiya kumwa mankhwalawa chifukwa cha zovuta zina. Kulankhulana molakwika ndi mankhwala osokoneza bongo kuyenera kupewedwa ndipo zoyipa zomwe zingachitike chifukwa cha mankhwala ziyenera kunenedwa molondola.
Kodi mudawonapo malonda a mankhwala atsopano omwe abwera pamsika omwe ali odzaza ndi anthu osangalala panthawi yamalonda kenako pamapeto pake, chifukwa makampani azamankhwala ali ndi udindo wovomerezeka kuchita izi, mawu ofulumira komanso otsika amawerengedwa mndandanda wowopsa wazotsatira zomwe nthawi zambiri zimathera ndiimfa? Zachidziwikire, makampani azamankhwala ayesa kuchepetsa zovuta zilizonse zomwe mankhwala osokoneza bongo angayambitse ngakhale, ndipo nthawi zambiri izi ndi zowona, zotsatirapo zake zitha kukhala zoyipa kuposa vuto loyambirira lomwe mankhwala akuyesera kukonza. Mofananamo, mayesero ambiri azachipatala amagwiritsa ntchito chilankhulo chomwe sichimafotokozera kwathunthu za kuwopsa kwa poizoni (komwe kumabweretsa kulumikizana molakwika) ndi zotsatirapo zamankhwala omwe apatsidwa.
Chifukwa chomwe kuwonongeka kwa mankhwala osokoneza bongo kumatsika pang'ono kwa wodwala chifukwa cha chilankhulo chonyenga komanso chophatikizira chomwe chimagwiritsidwa ntchito ndi makampani a pharma. Ndipo kuti amve alamu kwa asing'anga anzawo komanso ofufuza zamankhwala pankhaniyi, ofufuza zamankhwala ochokera ku Massachusetts General Hospital ku Boston adasindikiza nkhani mu New England Journal of Medicine. Munkhaniyi, apeza kuti mayesero azachipatala nthawi zambiri amafotokoza zovuta zoyipa za mankhwala a chemo ngati 'osamalika,' 'otetezeka komanso othandiza' kapena 'olekerera' pomwe palibe chilichonse chafotokozeretu kukula kwa vutoli. Mwachitsanzo, mu khansa colorectal kafukufuku pakati pa magulu awiri omwe amaonedwa kuti ndi 'olekerera bwino,' "zochitika zoyipa zidapangitsa kuti chemotherapy isachiritsidwe mu 39% ya odwala mgulu limodzi la mankhwala ndi 27% mu inayo. Onse, anthu 13 adamwalira ndi choipa "Chana A. Sacks et al, N ENGL J MED., 2019). Kuyika chizindikiro chofezeka chotere pamankhwala omwe zoopsa zake zidapangitsa kuti anthu ena amwalire ndizolakwika. Zomwe zimakhudza moyo wamunthu zikuwunikidwabe ndi maphunziro osawerengeka koma chofunikira ndichakuti maphunziro azachipatala amafunikira njira yatsopano momwe adzawadziwitsire omwe angawagwiritse ntchito ndi asing'anga za zomwe zingachitike chifukwa cha mankhwalawa.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Regorafenib monga chitsanzo cha mankhwala omwe ali ndi poizoni wofunikira
Regorafenib ndi chandamale khansa mankhwala omwe avomerezedwa ndi FDA kuti azichiza khansa ya colorectal ya metastatic pokhapokha ngati odwala alephera mitundu ingapo ya chemotherapy monga OXA, fluoropyridine, IRN based chemotherapies ndi anti-VEGF therapy. Mankhwala monga Regorafenib adalumikizidwa ndi poizoni wofunikira pamiyezo yovomerezeka, zomwe zidalamula kuunikanso kwadongosolo lake la mlingo ndi kuvomereza mbiri ya kawopsedwe pambuyo pake. Chifukwa chake ngakhale mankhwalawa atsimikiziridwa kuti ndi othandiza pothana ndi zotupa, madokotala amayenera kukhala osamala kwambiri popereka Mlingo komanso kudziwitsa odwala za poizoni omwe angabwere ndikumwa mankhwalawa. Mu kafukufuku wa ofufuza zachipatala ochokera ku yunivesite ya Columbia ku New York pa mphamvu ndi zotsatira za Regorafenib, kuyesa kwa GRID kunachitika ndikulembetsa anthu 199 omwe aliyense anatenga 160mg ya Regorafenib pakamwa kwa masabata 3 mwa 4 mkombero uliwonse ndi zotsatira zake zoipa 98% ya odwala komanso "zotsatira zoyipa zomwe zimanenedwa kuti zinali zowopsa pakhungu (56%), matenda oopsa (48.5%), kutsegula m'mimba (40%) ndi kutopa (38.6%)"Demetri GD et al, Lancet, 2013; Krishnamoorthy SK et al, Therap Adv Gastroenterol., 2015). Pamwamba pa izi, panali ngozi yowonongeka m'manja yomwe amanenedwa ndi odwala.
Chachikulu ndichakuti odwala amafunika kudziwa zomwe akulowa ndipo izi sizingatheke ngati angasocheretsedwe ndi mawu achinyengo kapena osachita mwadala (kusamvana) omwe amalephera kulongosola molondola zovuta zomwe zingakhalepo ngati poyizoni, kuti mankhwalawa atha kubweretsa .
Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.
Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.
Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kulosera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe khansa ndi zotsatira zake zokhudzana ndi chithandizo.