Hoʻokomo i ka hao Nutrient a me ka makaʻu o ka maʻi ʻaʻai

o ka Naauao

ʻO nā ʻike mai nā haʻawina like ʻole i manaʻo ʻia ka nui o ka hao/heme iron e lilo i mea pilikia no nā maʻi maʻi e like me ka maʻi maʻi umauma a me ka maʻi maʻi pancreatic; akā naʻe, hiki ke loaʻa ka hopena pale i ka nui o ka hao a i ʻole ka ʻai ʻole heme i nā maʻi maʻi maʻi colorectal a me esophageal. Ma muli o nā haʻawina i loiloi ʻia ma kēia blog, ma maʻi pū e like me ka ma'i ma'i 'a'ai a me ka ma'i 'a'ai prostate, 'a'ohe hui nui i 'ike 'ia. Pono nā haʻawina i wehewehe maikaʻi ʻia e hoʻokumu i kēia mau ʻike. ʻO ka lawe ʻana i nā mea hoʻohui hao me ka Erythropoiesis-stimulating agents for cancer chemotherapy-induced anemia (haʻahaʻa hemoglobin haʻahaʻa) hiki ke loaʻa kekahi mau pono. ʻOiai he mea nui ka ʻai ʻana i ka nui o ka hao no ka hana pono ʻana o ko mākou kino, ʻo kona ʻai nui ʻana hiki ke alakaʻi i nā hopena ʻaoʻao a hiki ke make i nā keiki. No laila, e nīnau i ke kauka ma mua o ka lawe ʻana i nā mea hoʻohui hao.

ʻO ka hao - ka mea pono nui

ʻO ka hao kahi mineral pono nui e pono ai no ka hana pono ʻana o hemoglobin, kahi protein i makemake ʻia no ka lawe ʻana i ka oxygen i loko o ke koko, a no ka ulu a me ke kūkulu ʻana. ʻOiai he mea waiwai nui, pono ke loaʻa ka hao mai kā mākou papaʻai. He mea nui ia i nā hana ʻē aʻe e like me ka hoʻokumu ʻana i ka serotonin, ka hana ʻana i nāʻiʻo, ka hana ʻana i ka ikehu, nā ʻōnaehana gastrointestinal, ka mālama ʻana i ka mahana o ke kino, ka synthes DNA a me ka hoʻoikaika ʻana i ka ʻōnaehana pale. 

Mālama nui ʻia ka hao i ke akepaʻa a me ka iwi o ka iwi ma ke ʻano he ferritin a i ʻole hemosiderin. Hiki ke mālama ʻia i loko o ka spleen, duodenum a me nā mākala iwi. 

Nā Kumuwaiwai Mea hao

ʻO kekahi o nā laʻana o nā kumu meaʻai no ka hao:

• ʻO ka meaʻai 
• ake
• mohihi
• kukui
• Nā hua maloʻo e like me nā lā maloʻo a me nā apricots
• Pī piʻa

Nā ʻano o ka Meaʻai Meaʻai

Aia ka haoʻai i nā ʻano ʻelua:

• Heme hao
• Hao hao ʻole

Loaʻa ka hao Heme ma kahi o 55-70% o ka huina hao mai nā huahana holoholona e like me ka ʻulaʻula, nā moa a me nā iʻa a ʻoi aku ka maikaʻi o ka lawe. 

Aia ka hao non-heme i ke koena o ka hao a me ka hao i loaʻa i nā mea kanu i hoʻokumu ʻia e like me nā legume a me nā palaoa, a me nā mea hoʻohui hao. He mea paʻakikī ke omo i ka hao mai nā meaʻai mea kanu. E ʻoluʻolu e hoʻohana i ka wikamina C e kōkua i ka omo hao.

Hōʻemi hao

ʻO ka hemahema o ka hao, i kapa ʻia he anemia, kahi ʻano kahi o ka nele o ka hao i loko o ke kino e hopena ai i kahi helu liʻiliʻi o nā kaola ʻulaʻula olakino hiki ke lawe i ka oxygen i nā aʻa. 

Hoʻololi ka ʻāpono o ka hao i kēlā me kēia lā me ka makahiki a me ke kāne.

• 8.7mg i ka lā no nā kāne ma mua o 18
• 14.8mg i ka lā no nā wahine mai 19 a 50 mau makahiki
• 8.7mg i ka lā no nā wahine ma mua o 50

Hiki ke loaʻa maʻamau kēia mau kālā mai kā mākou papaʻai.

ʻO ka hemahema hao ka mea nui o ka momona o ka honua. No laila, ma mua ka nānā nui e pili ana i ka haoʻai i ʻoi aku ka nui o ka hao. Eia nō naʻe, i nā wā i hala iho nei, e ʻimi pū ana nā mea noiʻi i nā hopena o ka nui o ka hao i loko o ke kino. Ma kēia blog, e nānā mākou i kekahi o nā noiʻi i loiloi i ka pilina ma waena o ka hao a me ka pilikia o nā ʻano maʻi ʻaʻai.

ʻO ka hui ma waena o ka Iron a me ka maʻi maʻi ʻaʻai

ʻO ka Iron a me ka Tumor Tissue Iron a me ka maʻi maʻi ʻaʻai o ka umauma

ʻO kahi meta-analysis i hana ʻia e nā mea noiʻi mai ke Kulanui ʻepekema ʻo Golestan, Ilam University of Medical Science, Shahid Beheshti University of Medical Science a me Birjand University of Medical Science i loiloi i ka hui ma waena o ka hao a me ka maʻi ʻaʻai o ka umauma. Ua komo ka ʻanalike me nā ʻatikala he 20 (e pili ana i ka poʻe 4,110 me 1,624 mau maʻi maʻi ʻaʻai umauma a me nā kāʻei 2,486) i paʻi ʻia ma waena o 1984 a me 2017 a loaʻa ma o ka ʻimi palapala ʻana ma PubMed, Scopus, Embase, Pūnaewele ʻepekema, a me Cochrane Library. (Akram Sanagoo et al, Caspian J Intern Med., Hoʻoilo 2020)

Ua ʻike ʻia ka loiloi i ka nui o ka maʻi kanesa o ka umauma me ka nui o ka hao i loko o nā pūʻulu kahi i ana ʻia ai ka hao i nā ʻiʻo umauma. Eia naʻe, ʻaʻole lākou i ʻike i kahi pilina ma waena o ka hao a me ka umauma Ka maʻi 'aʻai pilikia i nā pūʻulu kahi i ana ʻia ai ka hao ma ka lauoho poʻo. 

ʻO ka lawe hao, ke kūlana hao o ke kino, a me ka maʻi ʻaʻai umauma

Ua hana nā kānaka noiʻi mai ke Kulanui o Toronto a me ka mālama maʻi maʻi maʻi ʻo Kanada, ʻo Kanada i kahi hana me ka nānā ʻana e loiloi i nā hui ma waena o ka hao a me ke kūlana o ka hao a me ka maʻi ʻaʻai o ka umauma. Ua hoʻokomo ʻia 23 mau noiʻi no ka ʻimi noiʻi moʻomanaʻo moʻomanaʻo moʻomanaʻo ma MEDLINE, EMBASE, CINAHL, a me Scopus database a hiki i Kekemapa 2018. (Vicky C Chang et al, BMC Cancer., 2019)

Ua ʻike lākou i ka hoʻohālikelike ʻia me ka poʻe me ka ʻai heme hao haʻahaʻa loa, aia he 12% ka piʻi ʻana o ka maʻi ʻaʻai umauma i kēlā me nā mea heme hao kiʻekiʻe loa. Eia nō naʻe, ʻaʻole i loaʻa iā lākou kahi pilina koʻikoʻi ma waena o nā meaʻai, nā mea kōkua a i ʻole ka nui o ka lawe ʻana i ka hao a me ka maʻi maʻi maʻi umauma. Pono e wehewehe hou ʻia nā noiʻi hoʻokolohua e elucidate ʻoi aku ka pilina ma waena o ka hao a me ka maʻi ʻaʻai umauma.

Ka hopena o ka hoʻohui Antioxidant ma ka hui ma waena o kaʻai haoʻai a me ka maʻi maʻi ʻaʻai

ʻO kahi noiʻi i hana ʻia e nā mea noiʻi ma Palani ma 2016 i loiloi i ka hui ma waena o kaʻai a me ka maʻi ʻaʻai umauma maʻi, a me ka hiki ke hoʻololi ʻia e kahi hoʻopili antioksantant a me ka lawe lipid i nā wahine 4646 mai ka SU.VI.MAX hoʻokolokolo. Ma kahi o ka ukali maʻamau o 12.6 mau makahiki, ua hōʻike ʻia ʻo 188 mau maʻi maʻi ʻaʻai. (Abou Diallo et al, Oncotarget., 2016)

Ua ʻike ʻia ua hoʻopaʻa ʻia ka pilina o ka hao me ka hoʻonui ʻana i ka maʻi ʻaʻai o ka umauma, ʻoi aku hoʻi i nā wahine i hoʻopau i ka nui o nā lipid, akā naʻe, ua ʻike ʻia kēia hui no nā poʻe i kī ʻole ʻia me nā antioxidants i ka wā o ka hoʻokolokolo. Ua hoʻopau ka noiʻi ʻana ua hoʻonui ʻia paha ka makaʻu o ka umauma e ka hao-induced lipid peroxidation.

NIH-AARP Diet a me ke aʻo olakino

Ma kahi ʻimi ʻikepili ʻē aʻe o ka ʻike papaʻai mai 193,742 wahine postmenopausal i ʻāpana o ka ma ka NIH-AARP Diet a me ke aʻo olakino, me 9,305 hanana i loaʻa ʻia i nā maʻi maʻi umauma (1995-2006), ua ʻike ʻia ua pili ka lawe ʻana o ka hao heme kiʻekiʻe me kahi hoʻonui i ka makaʻu o ka umauma maʻi 'aʻai, ma ka laulā a ma nā maʻi ʻaʻai. (Maki Inoue-Choi et al, Int J Ka maʻi ʻaʻai., 2016)

ʻO ka hui ma waena o Iron a me Colorectal Cancer Risk

ʻO ka hao hao, nā mea hao hao a me ka makaʻu o nā Colectal Adenomas

Ua loiloi nā kānaka noiʻi mai ka Halemai o ka Lehulehu Zhejiang a me ka Haukapila Mua o ka Apana ʻo Fuyang ma Kina, i ka pilina ma waena o ka lawe hao, nā ʻikepili serum a me ka makaʻu o ka colorenal adenoma, e hoʻohana ana i ka ʻikepili mai nā ʻatikala he 10, e pili ana i nā hihia adenoma colorectal 3318, i loaʻa ma o ka palapala. ʻimi ma MEDLINE a me EMBASE a hiki i ka 31 Malaki 2015. (H Cao et al, Eur J Cancer Care (Engl)., 2017)

Ua ʻike ʻia ka noiʻi ʻana ua pili ka hoʻonui ʻia ʻana o ka hao heme me ka nui o ka makaʻu o ka colorectal adenoma, ʻoiai ʻo ka lawe ʻana i ka non-heme a i ʻole ka hao mea hoʻonui i hoʻemi ai i ka makaʻu o nā adenomas colorectal. Ma muli o ka palena o ka ʻikepili i loaʻa, ʻaʻohe hui ma waena o nā ʻikepili serum a me nā pilikia adenoma kala.

Loaʻa i ka hao hao a me ka zinc a me ka maʻi ʻaʻai kala

ʻO kahi haʻawina i hana ʻia e nā mea noiʻi mai ka Halemai Shengjing o ke Kulanui Lapaʻau Kina ma Kina i loiloi i nā pilina ma waena o ka lawe ʻana i ka hao heme a me ka zinc a me ka colorectal. Ka maʻi 'aʻai hanana. ʻEwalu mau haʻawina e pili ana i ka ʻai hao heme a me ʻeono mau haʻawina e pili ana i ka lawe ʻana i ka zinc i hoʻohana ʻia no ka nānā ʻana i loaʻa ma o ka huli palapala ma PubMed a me EMBASE waihona a hiki i Dekemaba 2012. (Lei Qiao et al, Cancer Causes Control., 2013)

Ua loaʻa kēia meta-analysis i ka hoʻonui nui ʻana o ka maʻi ʻaʻai maʻi colorectal me ka hoʻonui ʻia ʻana o ka hao heme a me ka hōʻemi nui ʻana o ka maʻi maʻi maʻi maʻi me ka hoʻonui ʻia o ka zinc.

ʻO ka hui ma waena o Iron a me Esophageal Cancer Risk

Ua hana nā kānaka noiʻi mai ke Kulanui ʻo Zhengzhou a me ke kula ʻo Zhejiang University ma Medicine i kahi ʻōnaehana ʻōnaehana e loiloi i ka pilina ma waena o ka lawe ʻana o ka hao a me ka zinc a me ka hao heme haʻahaʻa a me ka makaʻu o Esophageal Cancer. Ua loaʻa nā ʻikepili no ke kālailai mai nā ʻatikala 20 me 4855 mau hihia mai 1387482 poʻe i komo, i loaʻa mai i ka ʻimi noiʻi moʻokalaleo ma Embase, PubMed, a me nā pūnaewele ʻikepili pūnaewele ma o ʻApelila 2018. (Jifei Ma e al, Nutr Res., 2018)

Ua ʻike ʻia ke aʻo ʻana i kēlā me kēia hoʻonui ʻana o 5 mg / lā i ka huina nui o ka lawe hao i hoʻopili ʻia me kahi 15% hoʻēmi i ka makaʻu o ka Esophageal Cancer. Ua loaʻa ka hoʻoliʻiliʻi pilikia i nā heluna nui o ʻAsia. ʻO ka mea ʻē aʻe, ʻo kēlā me kēia hoʻonui ʻana o 1 mg / lā o ka lawe heme hao i pili me ka 21% hoʻonui i ka hopena o ka maʻi ʻaʻai Esophageal. 

ʻO ka hui ma waena o Iron a me Pancreatic Cancer Risk

ʻO kahi noiʻi i paʻi ʻia ma 2016 i loiloi i ka hui ʻana o ka ʻai ʻana o ka ʻiʻo, nā ʻano hana kuke ʻai a me ka hana ʻana a me ka hao heme a me ka ʻai mutagen me ka maʻi maʻi pancreatic ma ka NIH-AARP Diet and Health Study cohort e pili ana i 322,846 poʻe i komo he 187,265 mau kāne a he 135,581 wahine. Ma hope o ka hahai ʻana o 9.2 mau makahiki, 1,417 pancreatic Ka maʻi 'aʻai ua hōʻike ʻia nā hihia. (Pulkit Taunk et al, Int J Cancer., 2016)

Ua ʻike ʻia ua hoʻonui ʻia ka pilikia o ka maʻi ʻaʻai pancreatic me ka lawe ʻana o ka ʻiʻo holoʻokoʻa, ka ʻiʻo ʻulaʻula, ka ʻai i hoʻomoʻa ʻia me ka mahana wela, kaʻiʻo i hoʻomoʻa ʻia / barbequed, maikaʻi / maikaʻi maikaʻi kaʻiʻo a me ka hao heme mai ka ʻulaʻula. Ua ʻōlelo ʻia e nā kānaka noiʻi he nui nā noiʻi i wehewehe ʻia e hōʻoia i kā lākou loaʻa.

ʻO ka hui ma waena o ka Iron a me ka Prostate Cancer Risk

I loko o kahi noiʻi i paʻi ʻia e nā mea noiʻi mai nā EpidStat Institutes ma Michigan a me Wakinekona i ka US, ua loiloi lākou i ka pilina ma waena o nā hana kuke ʻai, heme iron, a me ka heterocyclic amine (HCA) a me ka maʻi ʻaʻai prostate e pili ana i nā paʻi 26 mai nā 19 ʻokoʻa cohort Studies . (Lauren C Bylsma et al, Nutr J., 2015)

ʻAʻole i loaʻa i kā lākou kālailai kahi pilina ma waena o ka ʻulaʻula a i ʻole ka hana ʻana i ka ʻiʻo a me ka maʻi ʻaʻai prostate; akā naʻe, ua ʻike lākou i kahi piʻi iki o ka makaʻu me ka ʻai ʻana i ka ʻino i hana ʻia.

ʻO ka hui ma waena o nā pae kiʻekiʻe o ka Serum a me ka maʻi ʻaʻa maʻi ʻaʻa

ʻO kahi noiʻi i hana ʻia e nā mea noiʻi mai ka Halemai ʻo Zhejiang Rongjun, ka Halemai ʻo Zhejiang Cancer, ka haukapila ʻo Cancer University University maʻi maʻi a me ka haukapila ʻo Lishui o ke Kulanui ʻo Zhejiang ma Kina i loiloi i ka hui ma waena o nā pae hao serum a me nā pilikia o ka maʻi ʻaʻa maʻi. Ua kiʻi ʻia ka ʻikepili no ka ʻikepili mai PubMed, WanFang, CNKI, a me SinoMed a hiki i Mar 1, 2018. Ua ʻike ʻia ka noiʻi ʻana ʻaʻole i pili ka nui o nā pae o ke serum me ka hopena o ka maʻi ʻaʻa maʻi. (Hua-Fei Chen et al, Cell Mol Biol (Noisy-le-grand)., 2018)

Hoʻohana o nā mea hoʻohui hao i ka hoʻokele o Chemotherapy-induced Anemia (haʻahaʻa pae hemoglobin) i nā maʻi maʻi maʻi.

ʻO kahi noiʻi i hana ʻia e ka Center for Evidence Base Medicine and Health Resulta Research, University of South Florida, Tampa, Florida, USA ua loiloi i nā pono a me nā mea ʻino e pili ana i ka hoʻohana ʻana o nā mea hoʻohui hao me nā ʻākoʻakoʻa stimulate Erythropoiesis (ESAs), i hoʻohana mau ʻia. e mālama i ka anemia chemotherapy-i hoʻokomo ʻia (hemoglobin pae haʻahaʻa) - CIA, a me Cochrane Database Syst hao wale i hoʻohālikelike ʻia me ESA wale nō i ka hoʻokele o CIA. (Rahul Mhaskar et al, Rev., 2016) Ua ʻike ʻia ka noiʻi ʻana me ka hoʻopili ʻia ʻana o ka hao me nā ESA no ka chemotherapy a ka chemotherapy-induced cancer e alakaʻi ai i ka pane hematopoietic kiʻekiʻe, hoʻēmi i ka makaʻi o ka transfusions o ka Blood Blood, a hoʻomaikaʻi i nā pae hemoglobin haʻahaʻa.

No laila, loaʻa paha nā hopena maikaʻi i ka lawe lāʻau hoʻopihapiha ma nā maʻi maʻi ʻaʻai me ka anemia kemo-i hoʻokomo ʻia (pae hemoglobin haʻahaʻa).

Panina

Hōʻike kēia mau haʻawina i nā hopena like ʻole o ka hao ma nā ʻano like ʻole maʻi pū. Ua ʻike ʻia ka hao nui i mea pilikia no nā maʻi kanesa e like me ka Breast Cancer a me ka Pancreatic Cancer, ma muli paha o kāna hana pro-oxidant e hiki ai ke alakaʻi i ka pōʻino DNA oxidative; akā naʻe, ʻike ʻia ka nui o ka hao a me ka hao ʻole heme, i loaʻa nā hopena pale i ka maʻi maʻi colorectal a me esophageal. I nā maʻi maʻi e like me ka maʻi kanesa a me ka maʻi maʻi prostate, ʻaʻohe hui nui i hōʻike ʻia. ʻO nā mea hoʻohui hao me nā ESA no ka maʻi maʻi chemotherapy-induced anemia (haʻahaʻa hemoglobin haʻahaʻa) hiki ke pōmaikaʻi. ʻOiai he mea nui ka ʻai ʻana i ka nui o ka hao no ka hana pono ʻana o ko mākou kino, ʻo kāna ʻai nui ʻana ma o nā mea hoʻopihapiha hiki ke alakaʻi i nā hopena ʻaoʻao e like me ka constipation a me ka ʻeha ʻōpū a hiki ke make i nā keiki. No laila, e nīnau i ke kauka ma mua o ka lawe ʻana i nā mea hoʻohui hao. Hiki ke loaʻa ka nui o ka hao mai nā meaʻai. 

He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.

ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.

E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.

ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy kahi e hoʻopili ai i ko lākou ola o ke ola a nānā i nā hoʻoponopono ʻokoʻa no ka maʻi ʻaʻai. Lawe ana i ka ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.

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