o ka Naauao
Ua hōʻike ʻia kahi noiʻi lāʻau lapaʻau ʻo ka hoʻohana ʻana (infusion) o ka ascorbate kiʻekiʻe (vitamina C) i hiki ke hoʻomaikaʻi i ke ola holoʻokoʻa o nā maʻi maʻi maʻi lolo (GBM) i loaʻa ka wānana maikaʻi ʻole. ʻO ka Vitamin C infusions (a me nā mea hoʻohui paha) i hāʻawi ʻia me ke ʻano o ka radiation mālama mālama a me ka mālama ʻana o Temozolomide no ka lolo. Ka maʻi 'aʻai hiki nō hoʻi ke hoʻohaʻahaʻa i nā hopena ʻaoʻao, pēlā e hoʻomaikaʻi ai i ka maikaʻi o ke ola o ka mea maʻi.
Ka maʻi ʻaʻai lolo - Glioblastoma
ʻO Glioblastoma (GBM) ka maʻi ʻaʻai nui o ka lolo mua. ʻO ke kūlana o ka mālama mālama ʻana no GBM me kahi hui pū ʻana o ka ʻoki ʻana o ka lolo i ukali ʻia e ka radiation radiation (RT) a me temozolomide (TMZ). I nā manawa he nui, ukali ʻia kēia e nā pōʻaiapuni hou aʻe o ka adjuvant TMZ post radiation. ʻOiai ke hoʻomohala ʻia ʻana o nā lāʻau lapaʻau maʻi ʻaʻai a me nā holomua a pau i ka mālama ʻana, hoʻomau mau ka wānana no nā mea maʻi GBM, me ke ola holoʻokoʻa o 14-16 mau mahina a me kahi ola 5 mau makahiki ma lalo o 10%. (ʻO Stupp R et al, ʻO ka Lancet Oncol., 2009; Gilbert MR et al, New Engl. ʻO J Med., 2014)
Nā Mea ʻai e ʻAi ai Ma hope o ka ʻike maʻi ʻaʻai!
ʻAʻohe ʻelua maʻi ʻaʻai. E hele i waho o nā kulekele meaʻai maʻamau no kēlā me kēia kanaka a hoʻoholo i nā koho pilikino e pili ana i ka meaʻai a me nā mea hoʻopihapiha me ka hilinaʻi.
ʻO ka Vitamin C / Ascorbic Acid Hoʻohana i ka maʻi ʻaʻai Brain
Nā haʻawina preclinical a me nā hoʻokolohua lapaʻau ma nā mea ʻē aʻe Ka maʻi 'aʻai Ua hōʻike nā hōʻailona i ka hopena maikaʻi o ka hoʻohana ʻana i nā infusion Vitamin C kiʻekiʻe e palekana a hoʻomaikaʻi i ka maikaʻi a me ka haʻahaʻa haʻahaʻa ke hoʻohana pū ʻia me nā lāʻau lapaʻau a me ka chemotherapy.
Ua hana ʻia kahi mea mua i loko o ka noiʻi hoʻokolohua kanaka ma 11 mau maʻi GBM hou ʻia e ka ʻOihana o Radiation Oncology ma ka haukapila o Iowa hospital, e nānā i ka palekana a me ka hopena o ka infusion ascorbate pharmacological, hāʻawi ʻia me ke kūlana o ka mālama mālama no GBM. (ʻO Allen BG et al, ʻo Clin Cancer Res., 2019) Hoʻokomo ʻia ka ascorbate mahele lāʻau he 3 mau manawa i ka pule i ka wā o ka pōʻai mālama RT / TMZ a ʻelua manawa i kēlā me kēia pule i ka wā o ka cyjuvant TMZ pōʻaiapuni. ʻO nā kumuhana 11 i kēia noi ʻana, 8 o lākou i loaʻa ka wānana maikaʻi ʻole e pili ana i ke kūlana unmethylated o kā lākou MGMT enzyme, kahi mea i ʻike ʻia no ka pane haʻahaʻa o TMZ. Hōʻike ka ʻikepili mōʻaukala i ke ola ʻana o nā mea maʻi GBM me ka ʻole o ka methylation promoter MGMT i nā mahina he 12 wale nō, ʻoiai ʻo nā mea i loko o kēia noi me ka ʻole o ka methylation hoʻolaha MGMT i ola holoʻokoʻa he 23 mau mahina me nā mea 3 e ola nei. ʻO nā hopena maikaʻi ʻole i ʻike ʻia e nā kumuhana ka waha maloʻo a me nā haʻalulu e pili ana i ka inforbate infusion, ʻoiai nā hopena ʻē aʻe iʻoi aku ka nui o ka luhi, nausea a me nā hanana hematological e pili ana me TMZ a me RT i hoʻemi ʻia.
Panina
Ke hōʻike nei kēia noi i ka hoʻokomo ʻana i nā lāʻau Vitamin C a ascorbate kiʻekiʻe paha i ka maʻi ʻaʻai lolo (GBM) e mālama ʻia me RT / TMZ therapy cycle hiki ke hoʻomaikaʻi i ke ola holoʻokoʻa, keu hoʻi i nā kumuhana me ka marker MGMT unmethylated i ʻike ʻia he prognosis maikaʻi ʻole. . Ke hōʻike nei ka noiʻi ʻaʻole hiki i ka infusion pharmacological ascorbate ke hoʻomaikaʻi wale i ka hoʻomanawanui o RT a me TMZ, akā hiki i ka hoʻonui ʻana i ka maikaʻi o ke ola o nā mea maʻi a me ka hoʻemi ʻana i ka lāʻau o ka radiation a me ka chemotherapy. Hōʻike ka infusion vitamin C (ascorbate) kiʻekiʻe i ka hoʻohiki i ka hoʻohaʻahaʻa ʻana i nā mea ʻino o nā chemotherapies e like me gemcitabine, carboplatin a me paclitaxel i nā maʻi pancreatic a me ovarian. (ʻO Welsh JL et al, Cancer Chemother Pharmacol., 2013; ʻO Ma Y et al, ʻo Sci. Unuhi. Med., 2014) Manaʻo nā mea noiʻi ʻo nā hopena o kā lākou noiʻi ʻana ma kēia pūʻulu liʻiliʻi loa o nā maʻi e hoʻohiki mau nei e loaʻa i kahi hoʻokolokolo hoʻokolohua hou aʻe i ka hopena o nā infusions Vitamin C a me nā mea hoʻohui i ka lolo. Ka maʻi 'aʻai.
He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.
ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.
E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.
Mea 'ai pilikino no ka ma'i 'a'ai!
Hoʻololi ka maʻi kanesa me ka manawa. Hoʻopilikino a hoʻololi i kāu meaʻai e pili ana i ka hōʻailona maʻi maʻi, ka mālama ʻana, ke ʻano o ka nohona, nā makemake meaʻai, nā allergies a me nā mea ʻē aʻe.
ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy kahi e hoʻopili ai i ko lākou ola o ke ola a nānā i nā hoʻoponopono ʻokoʻa no ka maʻi ʻaʻai. Lawe ana i ka ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.