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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Does Omega-3 Fatty Acid intake reduce the risk of Colorectal Adenomas?

Jul 23, 2021

Estimated reading time: 4 minutes
Home » Blogs » Does Omega-3 Fatty Acid intake reduce the risk of Colorectal Adenomas?

Highlights

A clinical trial named the VITAL study found that omega-3 fatty acid supplementation/intake is not associated with a reduced risk of colorectal cancer precursors such as colorectal adenomas and serrated polyps. The potential benefit of omega-3 fatty acid supplements/sources for reducing colorectal polyps in individuals with low blood levels of omega-3 fatty acids and African Americans requires confirmation in future studies.



Omega-3 Fatty Acids

Omega-3 Fatty Acids are a class of fatty acids which are not produced by the body and are obtained from our daily diet or dietary supplements. The three main types of omega-3 fatty acids are eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and alpha-linolenic acid (ALA). The omega-3 fatty acids EPA and DHA are mostly found in marine sources such as fishes and fish oil supplements while ALA is commonly obtained from plant sources such as walnuts, vegetable oils and seeds like Chia seeds and flax seeds.

Omega-3 Fatty Acid supplements have been in the spotlight for many years for their anti-inflammatory effects and benefits on cardiovascular health, brain and mental health, joint pain, etc. However, the role of omega-3 fatty acid or fish oil supplements in the prevention of different types of cancers is still unclear. Let us have a closer look into one of the studies published recently which evaluated the association of marine omega-3 fatty acid and the risk of colorectal adenomas.

Omega-3 Fatty Acid and Colorectal

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Omega-3 Fatty Acid and Colorectal Adenoma Risk


Researchers from the Harvard T.H. Chan School of Public Health, Boston, United states conducted an ancillary study within a large scale randomized clinical trial named the VITAL (Vitamin D and Omega-3 Trial) Study (Clinical Trial ID : NCT01169259), in order to evaluate the association of omega-3 fatty acid supplementation and the risk of colorectal adenomas and polyps. (Mingyang Song et al, JAMA Oncol. 2019) Polyps are small growths found on the inner lining of the colon or rectum.In this study, colorectal adenomas and polyps are considered as the precursors for colorectal cancer. Studying the effects of omega-3 fatty acid on these cancer precursors is beneficial, as it generally takes time for the cancer to develop and the effects of these supplements on the risk of cancer may become prominent only after several years. The study was done on 25,871 adults in the United States without cancer or cardiovascular disease, and included 12,933 adults who received 1g marine omega-3 fatty acid and 12938 control subjects, with a medium follow-up of 5.3 years.

Palliative Care Nutrition for Cancer | When Conventional Treatment is not Working

Towards the end of the study period, the researchers collected medical records from 999 participants who reported a diagnosis of colorectal adenomas/polyps. (Mingyang Song et al, JAMA Oncol. 2019) The key findings from this study are listed below:

  • 294 people from the group who received marine omega-3 fatty acid and 301 from the control group reported a diagnosis of colorectal adenomas.
  • 174 people from the omega-3 fatty acid group and 167 from the control group reported a diagnosis of serrated polyps.
  • According to a subgroup analysis, supplementation of marine omega-3 fatty acid was associated with a 24% reduced risk of conventional colorectal adenomas in individuals with low blood levels of omega-3 fatty acids.
  • Supplementation of marine omega-3 fatty acids appeared to have a potential benefit in the African American population but not in other groups.

Conclusion

In short, the study suggests that omega-3 fatty acid supplementation/intake is not associated with a reduced risk of colorectal cancer precursors such as colorectal adenomas and serrated polyps. More research is needed to confirm the potential benefits of this supplementation in individuals with low blood levels of omega-3 fatty acids and African Americans. Omega-3 fatty acids or fish oil supplements may still be beneficial for our heart, brain and mental health and will have to be taken in the right quantities to stay healthy. However, excessive supplementation/intake of omega-3 fatty acid/sources can be detrimental due to its blood-thinning effect, especially if you are already taking a blood-thinner or aspirin. Hence, before consuming the dietary supplements, always make it a point to discuss with your nutritionist or health care provider and understand the dosage of the supplement that suits you the best.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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