Ukufa kukaChadwick Boseman: I-Colorectal Cancer ku-Spotlight

Amaphuzu avelele

I-Colorectal Cancer isibuyile ekugqanyisweni ngokufa okudabukisayo kwesihlabani se-"Black Panther", u-Chadwick Boseman. Funda kabanzi mayelana nomdlavuza ka-Chadwick Boseman okubandakanya izinga lokushona kwawo kanye namazinga okufa, izimpawu, ukwelashwa kanye nezici eziyingozi kanye nomthelela ongaba khona ohlanganisa ukudla okuhlukahlukene kanye nezithako zokudla njengengxenye yokudla okungaba nawo ku-colorectal. umdlavuza ingozi kanye nokwelashwa.

Ukufa okubuhlungu nokungazelelwe kukaChadwick Boseman, owaziwa kakhulu ngendima yakhe njenge “King T'Challa” kumdlalo we-movie ka-2018 "Black Panther" ovela kwi-Marvel Cinematic Universe, kuthumele ama-shockwaves emhlabeni wonke. Ngemuva kwempi yeminyaka emine nomdlavuza wamathumbu, umlingisi waseHollywood washona ngomhlaka-28 Agasti 2020 ngenxa yezinkinga ezihlobene nokugula. UBoseman wayeneminyaka engama-43 kuphela lapho ahlaselwa yilesi sifo. Izindaba zokushona kwakhe zashiya umhlaba ubambe ongezansi, njengoba uBoseman agcina impi yakhe nomdlavuza wamathumbu ngasese futhi wakhuthazelela konke lokho. 

Ngokwesitatimende esikhishwe wumndeni wakhe ezinkundleni zokuxhumana, uChadwick Boseman watholakala enomdlavuza we-Stage 3 colon ngo-2016 ogcine udlulele ku-Stage 4, okukhombisa ukuthi umdlavuza ususabalele nakwezinye izingxenye zomzimba ngale komgudu wokugaya ukudla. Ngesikhathi elashwa umdlavuza okwakuhilela ukuhlinzwa okuningi nokwelashwa ngamakhemikhali, uBoseman uqhubeke nokusebenza wasilethela amafilimu amaningana ahlanganisa iMarshall, Da 5 Bloods, Ma Rainey's Black Bottom namanye amaningi. Ngenkathi elwa nomdlavuza wakhe ngasese, uChadwick Boseman onomusa kakhulu futhi othobekile wayevakashele izingane ezitholwe zinomdlavuza eSt.Jude Children's Research Hospital eMemphis, e2018.

UChadwick Boseman ushonele kwakhe nonkosikazi wakhe nomndeni wakhe eceleni kwakhe. Ngemuva kwezindaba ezishaqisayo ngokushona kwakhe, kuthuthuzelwe ezinkundleni zokuxhumana kubalingani bakhe nakubalandeli bakhe emhlabeni wonke.

Ukushona kabuhlungu kukaBoseman esemncane eneminyaka engama-43, kubuyise umdlavuza wamathumbu emuva obala. Nakhu konke okufanele sikwazi ngomdlavuza kaChadwick Boseman.

Konke Mayelana Nomdlavuza KaBoseman

Yini iCancer kanye neColorectal Cancers?

Umdlavuza wamakholoni wuhlobo lomdlavuza ovela odongeni lwangaphakathi lwamathumbu amakhulu olwaziwa nge-colon. Umdlavuza wamakholoni uvame ukuhlanganiswa nomdlavuza we-rectal ovela ku-rectum (indlela engemuva) futhi ubizwa ngokuthi ngama-colorectal cancer noma umdlavuza wamathumbu. 

Emhlabeni jikelele, umdlavuza obala ngokwezibalo ungowesithathu umdlavuza owenzeka kakhulu emadodeni futhi ungowesibili umdlavuza owenzeka kakhulu kwabesifazane (i-World Cancer Research Fund). Futhi ungumdlavuza wesithathu obulala kakhulu futhi owesine otholakala kakhulu emhlabeni (GLOBOCAN 2018). 

I-National Cancer Institute ilinganisela ukuthi amacala omdlavuza osanda kutholakala e-1,47,950 asanda kutholakala e-United States ngonyaka wezi-2020, kufaka phakathi umdlavuza wamakholoni angu-104,610 namacala womdlavuza onxenxela angama-43,340. (URebecca L Siegel et al, CA Cancer J Clin., 2020)

Ziyini izimpawu zeColorectal Cancer?

Umdlavuza we-Colorectal ikakhulu uqala njengokukhula okuncane kulwelwesi lwangaphakathi lwekholoni noma i-rectum ebizwa ngama-polyps. Kunezinhlobo ezimbili zama-polyps:

• Ama-polyps adenomatous noma ama-adenomas - angajika abe ngumdlavuza 
• Ama-polyp Hyperplastic and inflammatory - ngokuvamile angaguquki abe ngumdlavuza.

Njengoba ama-polyps evame ukuba mancane, abantu abaningi abanomdlavuza obala ngokwebala kungenzeka bangazitholi izimpawu ngesikhathi sokuqala komdlavuza. 

Ezinye zezimpawu nezimpawu ezibikwe ngomdlavuza obala ngokwezibalo yilezi: ukushintsha imikhuba yamathumbu efana nohudo, ukuqunjelwa, noma ukuncipha kwesitokisi okuqhubeka izinsuku eziningi, igazi esitokisini, amajaqamba esiswini, ubuthakathaka nokukhathala kanye nokwehla kwesisindo ebengahlosiwe. Eziningi zalezi zimpawu zingadalwa yizimo zezempilo ngaphandle komdlavuza obala ngamangqamuzana, njenge-irritable bowel syndrome. Kodwa-ke, kubalulekile ukuthi ubonane nodokotela wakho uma uhlangabezana nanoma yiziphi zalezi zimpawu nezimpawu ezihambisana nomdlavuza wobala.

Ayini amathuba okuba nomdlavuza weColorectal?

Ngokwe-American Cancer Society, owesilisa oyedwa kwabangu-1 nowesifazane oyedwa kwabangu-23 basengozini yokuba nomdlavuza wobala. Abantu asebekhulile abaneminyaka engaphezu kwengama-1 ubudala bathambekele kakhulu ekungenweni ngumdlavuza obomvu. Ngokuthuthuka kwakamuva kwezesayensi yezokwelapha, ama-polyps acolorectal manje atholakala kaningi ngokuhlolwa nokususwa ngaphambi kokuba akhule abe ngumdlavuza. 

Kodwa-ke, i-American Cancer Society yengeze ukuthi, ngenkathi izinga lezehlakalo kubantu asebekhulile abaneminyaka engama-55 noma ngaphezulu lehle ngo-3.6% unyaka nonyaka, lenyuke ngo-2% unyaka nonyaka eqenjini elincane elineminyaka engaphansi kwengama-55. Izinga lesifo somdlavuza esikhuphukile kubantu abasha lingabangelwa ukuhlolwa okuncane okujwayelekile kuleli qembu ngenxa yokuntuleka kwezimpawu, indlela yokuphila engenampilo kanye nokudla okunamafutha aphezulu, ukudla okuphansi kwe-fiber. 

Ngabe umuntu osemncane njengoChadwick Boseman angabulawa yiColon Cancer?

Ake sibone ukuthi izibalo zithini!

Ngokwelashwa okuthuthukisiwe komdlavuza obala ngokobulili kanye nokuhlolwa okujwayelekile ukuthola umdlavuza kusenesikhathi (okulula ukuselapha), izinga lokufa lilonke liye laqhubeka ukwehla eminyakeni edlule. Kodwa-ke, ngokwe-American Cancer Society, ukufa kwabantu ababulawa ngumdlavuza obala ngokobulili phakathi kwabantu abaneminyaka engaphansi kwengama-55 kukhuphuke ngo-1% ngonyaka kusuka ngo-2008 kuya ku-2017. 

I-American Cancer Society ibuye yaqokomisa ukuthi phakathi kwazo zonke izinhlanga e-United States, abantu base-Afrika baseMelika banesibalo esiphezulu somdlavuza namazinga okufa kwabantu. Umuntu ubuye abe sengozini uma esinye sezihlobo zakhe zegazi sinomdlavuza obomvu. Uma amalungu angaphezu kwelilodwa avela emndenini abenomdlavuza omuncu, lowo muntu usengozini enkulu yokuthola lesi sifo.

Ngokwemininingwane okwabelwana ngayo ezinkundleni zokuxhumana, ngesikhathi kutholakala ukuthi umdlavuza kaChadwick Boseman wahlukaniswa njengomdlavuza wekoloni weSigaba III. Lokhu kusho ukuthi umdlavuza usuvele ukhulile ngokusebenzisa ulwelwesi lwangaphakathi noma ezingxenyeni zemisipha yamathumbu futhi ususabalalele kuma-lymph node noma ku-nodule of tumor in izicubu ezizungeze ikholoni ezingabonakali njengama-lymph node. Amathuba okusinda kulo mdlavuza axhomeke kakhulu ekutheni utholakale nini. Ukube uChadwick Boseman wabhekana nezimpawu phambilini nokuhlolwa kwenziwa ngaphambili kakhulu, mhlawumbe, odokotela bebengasusa ama-polyps ngaphambi kokuthi aphenduke umdlavuza obala noma bangabamba umdlavuza kusenesikhathi okulula kakhulu ukuselapha. 

I-American Cancer Society incoma ukuthi abantu abasengozini emaphakathi yomdlavuza obala ngokobulili kufanele baqale ukuhlolwa njalo beneminyaka engama-45.

Singazilawula yini izinto ezithile eziyingozi ukuze siqhelelane neCancer of Chadwick Boseman?

Ezinye zezinto eziyingozi zomdlavuza obala okubandakanya iminyaka yobudala, ubuhlanga nobuzwe, umlando womuntu siqu nowomndeni wama-polyps acolorectal noma umdlavuza we-colorectal, umlando wesifo samathumbu esivuthayo, uhlobo lwesifo sikashukela sohlobo lwesibili kanye nama-syndromes azuzwe njengefa axhumene nomdlavuza we-colorectal cancer, awekho ngaphansi kwethu ( I-American Cancer Society). 

Kodwa-ke, ezinye izinto ezinobungozi njengokukhuluphala ngokweqile / ukukhuluphala ngokweqile, ukungasebenzi komzimba, amaphethini wokudla angenampilo, ukudla ukudla okungalungile nezithasiselo, ukubhema nokuphuza utshwala, kungalawulwa / kulawulwe yithi. Ukulandela indlela yokuphila enempilo kanye nokudla ngendlela efanele nokuzivocavoca umzimba njalo kungasisiza sinciphise amathuba okuba nomdlavuza. 

Ngabe ukuhlolwa kweGenomic kungasiza ekuboneni amathuba okuba nomdlavuza weColorectal?

Ngokusho kwe-American Cancer Society, cishe abantu ababalelwa ku-5% ababa nomdlavuza obala ngamakhanda bazuze izakhi zofuzo ezidala ama-syndromes ahlukene axhumene nomdlavuza obomvu. Ukuhlolwa kofuzo kungasiza ukukhomba ukuthi ngabe umuntu uzuze njengelifa yini izakhi zofuzo ezingadala ama-syndromes anjalo angaholela kumdlavuza obala i-Lynch syndrome, i-familial adenomatous polyposis (FAP), i-Peutz-Jeghers syndrome ne-polyposis ehlobene ne-MUTYH.

• I-Lynch syndrome, ebanga cishe u-2% kuya ku-4% wawo wonke umdlavuza obala ngokwezibalo, ikakhulu idalwa yisici esizuzwe njengefa kuzinhlobo zofuzo ze-MLH1, MSH2 noma i-MSH6 ngokuvamile ezisiza ukulungisa i-DNA eyonakele.

• Ukuguqulwa okuzuzwe njengefa kuhlobo lwe-adenomatous polyposis coli (APC) kuxhunyaniswe nomndeni we-adenomatous polyposis (FAP) obala u-1% wawo wonke umdlavuza onemibala egqamile. 

• I-Peutz-Jeghers syndrome, isifo esingajwayelekile esizuzwe njengefa esixhunyaniswe nomdlavuza obomvu, sibangelwa ukuguqulwa kohlobo lwe-STK11 (LKB1).

• Esinye isifo esingajwayelekile esizuzwa njengefa esibizwa ngokuthi yi-MUTYH-polyposis esivame ukuholela kumdlavuza sisencane futhi sidalwa ukuguquka kwezakhi zofuzo ku-MUTYH gene, isakhi sofuzo esibambe iqhaza “ekuhloleni” i-DNA nokulungisa noma yimaphi amaphutha.

Imiphumela yokuhlolwa kofuzo inganikeza ochwepheshe bakho bokunakekelwa kwempilo imininingwane ebalulekile engabasiza bakuhlelele futhi bakwenzele izinqumo ezingcono, ngisho nangaphambi kokuqala kwesifo. Lokhu kungasiza futhi abantu abasha abanomlando womndeni womdlavuza obala ngokobulili, ukugwema ukutholakala ezinyangeni ezizayo lapho umdlavuza ususabalele nakwezinye izingxenye zomzimba.

Ingabe Ukudla / Ukudla / Izithasiselo Kungaba Nethonya Kubungozi Bomdlavuza KaChadwick Boseman noma Ukwelashwa Komdlavuza Okhanyayo?

Abaphenyi emhlabeni jikelele benze ucwaningo oluningi kanye nokuhlaziywa kwe-meta ukuhlola inhlangano yokufaka ukudla okuhlukahlukene nezithasiselo njengengxenye yokudla okunobungozi bokuthola i-Colorectal Cancer kaChadwick Boseman kanye nomthelela wazo ezigulini zomdlavuza. Ake sibheke kokutholakele okuyinhloko kwezinye zalezi zifundo! 

Ukudla / Ukudla / Izithasiselo ezinganciphisa ubungozi bomdlavuza weColorectal Cancer kaChadwick Boseman

Ukubandakanya ukudla okulungile ngokwesayensi kanye nezithasiselo njengengxenye yokudla kungasiza ekunciphiseni ubungozi bomdlavuza obusabekayo kaChadwick Boseman.

1. I-Fiber Yokudla / Izinhlamvu Eziphelele / I-Rice bran

• Ocwaningweni lwakamuva olwenziwe abacwaningi baseHenan, eChina, bathole ukuthi uma beqhathaniswa nalabo abadla okusanhlamvu okuphansi kakhulu, abantu abadla kakhulu bangase babe nokuncipha okukhulu kwe-colorectal, gastric and esophageal. zomdlavuza. (Xiao-Feng Zhang et al, Nutr J., 2020)

• Kokunye ukuhlaziywa kwe-meta okwenziwe ngabaphenyi baseNingizimu Korea nase-United States ngonyaka ka-2019, bathole ukuthi yonke imithombo ye-fiber yokudla inganikeza izinzuzo ekuvikeleni umdlavuza obala, ngenzuzo enamandla kunazo zonke etholakala nge-fiber yokudla okusanhlamvu / okusanhlamvu okuphelele. Oh et al, Br J Nutr., 2019)

• Ucwaningo olushicilelwe kwiNutrition and Cancer Journal ngo-2016 luye lwaphakamisa ukuthi ukwengeza i-rice bran ne-navy bean powder ekudleni kungashintsha i-gut microbiota ngendlela engasiza ekwehliseni ubungozi bomdlavuza obomvu. (U-Erica C Borresen et al, Umdlavuza weNutr., 2016)

2. imidumba

Ekuhlaziyweni kwe-meta okwenziwe ngabaphenyi baseWuhan, eChina, bathole ukuthi ukusetshenziswa okuphezulu kwemidumba njengophizi, ubhontshisi kanye nobhontshisi kungahle kuhlotshaniswe nengozi encishisiwe yomdlavuza obala ngokombala, ikakhulukazi kwabase-Asiya. (Beibei Zhu et al, Sci Rep., 2015)

3. Ukudla kwamaProbiotic / iyogathi

• Abaphenyi abavela eChina nase-United States bahlaziye idatha evela emadodeni angama-32,606 ku-Health Professionals Follow-up Study (HPFS) kanye nabesifazane abangama-55,743 e-Nurses 'Health Study (NHS) futhi bathola ukuthi ukuthatha iyogathi kabili noma ngaphezulu ngesonto kwehliswe ngo-19%. engozini yama-polyps ajwayelekile we-colorectal kanye nokuncipha kwe-26% engcupheni yama-polyps afriziwe emadodeni, kepha hhayi kwabesifazane. (Xiaobin Zheng et al, Gut., 2020)

• Kwesinye isifundo, abacwaningi abavela e-United States bahlaziya idatha evela emadodeni angama-5446 esifundweni saseTennessee Colorectal Polyp Study kanye nabesifazane abayi-1061 esifundweni iJohns Hopkins Biofilm Study futhi baphetha ngokuthi ukudla i-yogurt kungahle kuhlotshaniswe nokwehla kwengozi ye-hyperplastic ne-adenomatous (umdlavuza) polyps. (USamara B Rifkin et al, Br J Nutr., 2020)

4. Imifino ye-Allium / Garlic

• Ukuhlaziywa kwe-meta okwenziwe ngabaphenyi base-Italy kutholakale ukuthi ukutholakala okuphezulu kwegalikhi kungasiza ekwehliseni ubungozi bomdlavuza obumbala nokudla okuphezulu kwemifino ehlukene ye-allium kungahle kuhlotshaniswe nokwehla kwengozi yama-polyps adolovu (umdlavuza) . (UFederica Turati et al, Mol Nutr Food Res., 2014)

• Ucwaningo olususelwa esibhedlela olwenziwe ngabaphenyi beSibhedlela iChina Medical University phakathi kukaJuni 2009 noNovemba 2011, luthole ukwehla kwengozi yomdlavuza obala kumadoda nabesifazane abasebenzisa kakhulu imifino ye-allium ehlanganisa ugalikhi, izingongolo zikagalikhi, ilikhi, u-anyanisi , no-anyanisi wasentwasahlobo. (Xin Wu et al, Asia Pac J Clin Oncol., 2019)

5. Isaqathe

Abacwaningi abavela eNyuvesi yase-Southern Denmark bahlaziye idatha yocwaningo lweqembu elikhulu elihlanganisa abantu baseDenmark abangu-57,053 futhi bathola ukuthi ukudla okuphezulu kakhulu izaqathi eziluhlaza, ezingaphekiwe kungase kube wusizo ekwehliseni i-colorectal. umdlavuza ingozi, kodwa ukudla izaqathi eziphekiwe kungase kungayinciphisi ingozi. (Deding U et al, Nutrients., 2020)

6. Izithako zeMagnesium

• Ukuhlaziywa kwe-meta kwezifundo ezizayo ze-7 cohort kutholakale ukuhlangana okuphawulekayo kwezibalo zokwehlisa ingozi yomdlavuza obala nge-Magnesium engxenyeni ye-200-270mg / ngosuku. (Qu X et al, Eur J Gastroenterol Hepatol, 2013; Chen GC et al, Eur J Clin Nutr., 2012)  

• Ucwaningo olubheke ukuhlangana okuzayo kwe-serum kanye ne-Magnesium yokudla enezehlakalo zomdlavuza obala, kuthole ingozi ephezulu yomdlavuza obala nge-serum ephansi iMagnesium phakathi kwabesifazane, kodwa hhayi abesilisa. (UPolter EJ et al, iCancer Epidemiol Biomarkers Prev, 2019)

7. Nuts

Ekuhlaziyweni kwe-meta okwenziwe ngabaphenyi baseKorea, bathole ukuthi ukusetshenziswa kakhulu kwamantongomane afana nama-alimondi, amakinati kanye nama-walnuts kungasiza ekwehliseni ingozi yomdlavuza obala phakathi kwabesifazane nabesilisa. (Jeeyoo Lee et al, Nutr J. , 2018)

Umthelela Wezidlo / Ukudla / Izithasiselo ezahlukahlukene ezigulini ezinomdlavuza weColorectal kaChadwick Boseman

1. ICurcumin isiza ukuthuthukisa impendulo ye-FOLFOX chemotherapy

Isivivinyo somtholampilo sakamuva esenziwe ezigulini ezinomdlavuza we-metastatic colorectal (NCT01490996) sithole ukuthi inhlanganisela yeCurcumin, isithako esiyinhloko esitholakala ku-spice Turmeric, kanye nokwelashwa ngamakhemikhali e-FOLFOX kungaphepha futhi kubekezeleleke kwiziguli ezinomdlavuza, ngokuqhubeka ngokukhululeka kusinde Izinsuku ezingama-120 ubude nokusinda okuphelele kuphindwe kabili eqenjini lesiguli elithole le nhlanganisela, uma kuqhathaniswa neqembu elithole i-FOLFOX chemotherapy yodwa (UHowells LM et al, J Nutriti, 2019).

2. UGenistein angahle aphephe ukuhambisana ne-FOLFOX chemotherapy

Olunye ucwaningo lwakamuva olwenziwe ngabaphenyi e-Icahn School of Medicine eNtabeni iSinayi, eNew York lukhombise ukuthi kuphephile ukusebenzisa isengezo se-soy isoflavone Genistein kanye ne-FOLFOX chemotherapy ekwelapheni umdlavuza we-metastatic colorectal, ongcono kakhulu ukuphendula okuphelele (BOR) ezigulini ezithatha i-chemotherapy kanye noGenistein (61.5%), uma kuqhathaniswa ne-BOR ebikiwe ezifundweni zangaphambili kulabo abelashwa i-chemotherapy bodwa (38-49%). (NCT01985763; Pintova S et al, Cancer Chemotherapy & Pharmacol., 2019; USaltz LB et al, J Clin Oncol, 2008)

3. Ukuxhaswa kweFisetin kunganciphisa ama-Pro-Inflammatory Markers

Ucwaningo oluncane lomtholampilo lwabaphenyi bezokwelapha abavela e-Iran lukhombise izinzuzo ze-flavonoid fisetin, kusuka kwizithelo ezinjengama-strawberry, ama-apula kanye namagilebhisi, ekwehliseni izimpawu zomdlavuza ezivuvukala kanye nezimpawu zemetastatic ezifana ne-IL-8, hs-CRP ne-MMP-7 ezigulini ezinomdlavuza lapho zinikezwa kanye nokwelashwa kwazo ngamakhemikhali okusiza. (UFarsad-Naeimi A et al, Umsebenzi Wokudla. 2018)

4. Ijusi le-Wheatgrass linganciphisa ukulimala kwe-chemotherapy okuhambisana nemithambo yegazi

Ucwaningo lwakamuva olwenziwe ngabaphenyi beRambam Health Care Campus kwa-Israel lubonise ukuthi ijusi le-wheatgrass elinikezwe iziguli ezinomdlavuza wesigaba II-III kanye nokwelashwa kwazo ngamakhemikhali okunciphisayo kunganciphisa i-chemotherapy ehambisana nokulimala kwemithambo, kuyilapho kungenamthelela ekusindeni jikelele. (UGil Bar-Sela et al, Ijenali ye-Clinical Oncology, 2019).

5. I-Magnesium kanye namazinga anele e-Vitamin D3 kunganciphisa zonke izimbangela zokufa kwabantu

Ucwaningo lwakamuva luthole ukwehla kwengozi yokufa kwabantu kuzo zonke izifo ezigulini ezinomdlavuza onamazinga aphezulu okudla iMagnesium kanye namazinga anele eVitamin D3 uma kuqhathaniswa neziguli ezazintula iVitamin D3 futhi ezazidla kancane iMagnesium. (UWesselink E, u-Am J woMtholampilo Wezempilo., 2020) 

6. Ama-Probiotic angasiza ekuvimbeleni ukutheleleka kwangemva kokuhlinzwa

Ukuhlaziywa kwe-meta okwenziwe ngabaphenyi baseChina kutholakale ukuthi ukutholakala kwama-probiotic kungaba nomthelela ekwehliseni izinga lokutheleleka jikelele ngemuva kokuhlinzwa ngokwebala. Baphinde bathola ukuthi izehlakalo zokutheleleka kwamanxeba okuhlinzwa kanye nenyumoniya zincishisiwe ngama-probiotic. (UXiaojing Ouyang et al, Int J Colorectal Dis., 2019)

7. I-Probiotic Supplementation inganciphisa isifo sohudo esibangelwa imisebe

Ucwaningo olwenziwe ngabaphenyi baseMalaysia luthole ukuthi, uma kuqhathaniswa nalabo abangawasebenzisi ama-probiotic, iziguli ezithathe ama-probiotic zihlotshaniswa nengozi ephansi yohudo olubangelwa yimisebe. Kodwa-ke, lolu cwaningo alutholanga kuncishiswa okuphawulekayo kuhudo olwenziwe ngemisebe ezigulini ezithola ukwelashwa ngemisebe kanye ne-chemotherapy. (UNavin Kumar Devaraj et al, Amakhemikhali., 2019)

8. I-Polyphenol Rich Foods / Pomegranate Extract inganciphisa i-Endotoxemia

Ukudla okungenampilo namazinga okuxineka kungakhuphula ukukhishwa kwama-endotoxin egazini adala ukuvuvukala futhi angaba yisandulela somdlavuza obala ngokwezifo. Ucwaningo lomtholampilo olwenziwe yisibhedlela eMurcia, eSpain luthole ukuthi ukudla ukudla okune-polyphenol okunothile njengehalananda kungasiza ekwehliseni i-endotoxemia ezigulini ezinomdlavuza ezisanda kutholakala. (UGonzález-Sarrías et al, Ukudla nomsebenzi we-2018)

Ukudla / Ukudla / Izithasiselo ezingakhuphula iChadwick Boseman's Colorectal Cancer Risk noma zilimaze Ukwelashwa Komdlavuza

Ukufaka ukudla okungalungile nezithasiselo njengengxenye yokudla kungakhuphula ubungozi besifo somdlavuza ongafani nse kaChadwick Boseman.

1. Inyama Ebomvu Neyenziwe 

• Ukuhlaziywa kwemininingwane evela kwabesifazane abangama-48,704 abaneminyaka ephakathi kuka-35 kuya kwengu-74 ababengabahlanganyeli base-US nasePuerto Rico abazinze ezweni lonke abazoba yiqembu loDade Study bathola ukuthi ukudla okuphezulu kwansuku zonke kwenyama ecutshiwe kanye nemikhiqizo yenyama ebomvu ebiwe / eyosiwe kufaka phakathi ama-steaks nama-hamburger kuhlotshaniswa ngengozi eyengeziwe yomdlavuza onobala kwabesifazane. (USuril S Mehta et al, I-Cancer Epidemiol Biomarkers Prev., 2020)

• Abaphenyi baseChina bahlole izimbangela zomdlavuza obala e-China bathola ukuthi imbangela enkulu yesithathu kwaba wukudla okuphezulu kwenyama ebomvu nocutshungulwayo okwabalelwa ku-8.6% wesigameko somdlavuza ombaxambili. (UGu MJ et al, iBMC Cancer., 2018)

2. Iziphuzo / Iziphuzo ezineshukela

Ukuphuza njalo iziphuzo neziphuzo ezinoshukela kuholela emazingeni aphezulu kashukela egazini. Esifundweni sokubuyela emuva esenziwe ngabaphenyi eTaiwan, bathole ukuthi amazinga aphezulu kashukela egazi angathinta imiphumela yokwelashwa kwe-oxaliplatin ezigulini zomdlavuza weColorectal. (Yang IP et al, Ther Adv Med Oncol., 2019)

3. Izambane 

Abaphenyi be-University of Tromsø-I-Arctic University yaseNorway kanye neDanish Cancer Society Research Center, eDenmark bahlole imininingwane evela kwabesifazane abangama-79,778 abaneminyaka ephakathi kuka-41 no-70 eminyakeni yocwaningo lwaseNorway Women and Cancer futhi bathola ukuthi ukusetshenziswa okuphezulu kwamazambane kungahle kuhlotshaniswe ingozi ephezulu yomdlavuza obala. (ULene A lisli et al, Umdlavuza Wezakhi., May-Jun 2017) 

4. Izithako ze-Vitamin B12 ne-Folic Acid

Ukuhlaziywa kwedatha evela ocwaningweni lwesilingo somtholampilo okuthiwa yi-B-PROOF (B Vitamins for the Prevention of Osteoporotic Fractures) isilingo esenziwe eNetherlands sathola ukuthi i-folic acid ne-vitamin-B12 supplementation yesikhathi eside yayihlotshaniswa nengozi ephezulu kakhulu yomdlavuza onobala. (U-Oliai Araghi S et al, iCancer Epidemiol Biomarkers Prev., 2019).

5. Utshwala

Ukuhlaziywa kwe-meta okwenziwe ngabaphenyi beZhejiang University School of Public Health, eChina kutholakale ukuthi ukuphuza utshwala obuningi okulingana ne- ≥50 g / ngosuku lwe-ethanol kungakhuphula ubungozi bokufa komdlavuza obuluhlaza. (UShaofang Cai et al, i-Eur J Cancer Prev., 2014)

Ukuhlaziywa kwe-meta kwakamuva kwezifundo eziyi-16 ezihlanganisa i-colorectal eyi-14,276 umdlavuza amacala kanye nezilawuli eziyi-15,802 zithole ukuthi ukuphuza kakhulu (ngaphezu kweziphuzo ezi-3/ngosuku) kungase kuhlotshaniswe nokwanda okuphawulekayo engozini yomdlavuza we-colorectal. (USara McNabb, Int J Cancer., 2020)

Isiphetho

Ukushona okudabukisayo kuka-Chadwick Boseman kusuka kukholoni/colorectal umdlavuza eneminyaka engu-43 uye waqwashisa ngengozi yokuba nalesi sifo ekuqaleni kwempilo (enezimpawu ezincane ezinyathelweni zokuqala). Uma unomlando womndeni womdlavuza, thola ukuhlolwa kofuzo ukuze uqinisekise ukuthi awuzuzanga ukuguqulwa kwezakhi zofuzo ezihlobene nama-syndromes athile angaholela kumdlavuza we-colorectal.

Ngenkathi elashwa noma ezama ukuziqhelelanisa nomdlavuza onjengaleyo uChadwick Boseman anqotshwa kuyo, ethatha umsoco / ukudla okulungile okubandakanya ukudla okulungile nezindaba ezenezelayo. Ukulandela indlela yokuphila enempilo kanye nokudla okubandakanya ukudla okune-fiber okufana nokusanhlamvu okuphelele, okusanhlamvu, imifino, amantongomane nezithelo, kanye nokwenza izivivinyo ezijwayelekile kungasiza ekwehliseni ubungozi bomdlavuza onjengomdlavuza omubi kaChadwick Boseman, ukusekela ukwelashwa nokunciphisa izimpawu zayo.

Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.

Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.

Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.

Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy ezithinta ikhwalithi yempilo yazo futhi zibheke ezinye izindlela zokwelapha umdlavuza ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.

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