I-Hip, Joint, Lower Back kanye ne-Bone Pain ezigulini zomdlavuza

Amaphuzu avelele

Ubuhlungu bezinqulu, obuhlangene, obuphansi noma obuphansi buwuphawu oluvame kakhulu/uphawu/umphumela ongaseceleni ohambisana nezimo eziningi zezokwelapha ezihlanganisa imidlavuza efana nomdlavuza wamathambo oyisisekelo nowesibili, umdlavuza osezingeni eliphezulu onemetastasis emathanjeni, i-chondrosarcoma kanye ne-leukemia. Izifundo zelebhu ezihlukene kanye nezivivinyo ezimbalwa zabantu ziphakamisa i-Omega-3 fatty acids, i-Curcumin, Vitamin D3 kanye ne-Glucosamine ene-Chondroitin njengezithako ezithembisayo ezingase zibe namandla okunciphisa ubuhlungu be-musculoskeletal okuhlanganisa ubuhlungu bamalunga, i-hip, amathambo kanye nomgogodla ezigulini ezinomdlavuza, ikakhulukazi umdlavuza webele. Ngaphambi kokuthatha ngokungahleliwe lezi zithako zokudla ngenxa yobuhlungu bethambo, iziguli ezinomdlavuza kufanele zixoxisane nochwepheshe bazo bezempilo ukuze ziqhelelane nokusebenzelana okungafuneki nokwelashwa okuqhubekayo.

Ngabe ithambo, inqulu, amalunga okuhlangana kanye naphansi iqolo kuwuphawu lweCancer?

Ubuhlungu bemisipha obufaka phakathi i-hip, ijoyini, iqolo elingezansi kanye nobuhlungu bethambo kuyinkinga ejwayelekile yezempilo emhlabeni jikelele. Ngokusho kwe-World Health Organisation, ukusabalala kwesikhathi sokuphila kwezinhlungu ezingemuva ezingemuva kuzungeze ama-60% kuye kuma-70%. 

Ubuhlungu be-Hip, ijoyini, iqolo elingezansi kanye nethambo bungahlotshaniswa nezimo eziningi zezokwelapha ezibandakanya isifo samathambo, ukulimala, izinzwa ezicindezelwe nomdlavuza. 

Ubuhlungu beMisculoskeletal kufaka phakathi i-hip, ithambo nobuhlungu obuphansi emuva kuyisibonakaliso / uphawu olujwayelekile kakhulu kumdlavuza onjenge:

• Umdlavuza wethambo: Ubuhlungu ethanjeni elithintekile lomdlavuza ngenye yezimpawu ezivame kakhulu zomdlavuza wamathambo (umdlavuza oyinhloko nowesibili).

• I-leukemia noma i-Myelodysplastic syndromes (MDS): Emdlavuzeni onjenge-leukemia ne-MDS, umnkantsha ugcwala ngokweqile ngenxa yokukhiqizwa okungalawulwa kohlobo lwamaseli amhlophe egazi okuholela ebuhlungwini bamathambo obuqala ekuqaleni ezingalweni nasemilenzeni bese kuthi esinqeni.

• Umdlavuza we-Metastatic noma umdlavuza ophakeme: Kuma-cancer aphakeme noma umdlavuza one-metastasis (njengasesimweni se-metastatic prostate noma umdlavuza webele), umdlavuza uvame ukusabalala uye emathanjeni omgogodla, izimbambo, i-hip noma i-pelvis okubangela ubuhlungu be-hip.

• I-Chondrosarcoma: Luhlobo lomdlavuza olungandile oluvame ukuqala emathanjeni noma izicubu ezithambile eziseduze kwamathambo. Izicubu ze-chondrosarcoma zithinta kakhulu izizinda ze-pelvis, hip kanye nehlombe yingakho ubuhlungu kulezi zindawo kuyisibonakaliso esivamile salo mdlavuza. Kodwa-ke, kwezinye izimo isisekelo sogebhezi siyathinteka.

• Umdlavuza Wamaphaphu: Uma kwenzeka isimila sivela ohlangothini olungemuva lwephaphu, ubuhlungu bungadlulela kuze kufike emuva engezansi 

Ukuhlangana phakathi kwe-Hip Pain ne-Prostate, umdlavuza webele namaphaphu

Ngaphezulu kwamaphesenti angama-60% eziguli ezinomdlavuza wesibeletho ezithuthukile ezithuthukisa imethastasis yamathambo kanye nobuhlungu obulandelayo emathanjeni nasinqeni.

Ocwaningweni olwenziwe ngabantu phakathi kweziguli zase-United Kingdom ezinakekelwa ngokuyinhloko olwenziwe ngabaphenyi baseKeele University e-United Kingdom, bagqamise ukuthi izinkinga ezintsha zangasemuva, zesinqe nezentamo zitholakale zihambisana nokutholakala kwesifo sendlala, isifuba kanye Umdlavuza wamaphaphu, ikakhulukazi unyaka ngemuva kokubonisana ngezinkinga zangemuva, zenyonga nezentamo. Bathola ukuthi ingozi yomdlavuza wendlala yesinye iphakeme ngokuphindwe kahlanu ngonyaka olandelayo, phakathi kwalawo madoda abonisana nobuhlungu beqolo. (UKelvin P Jordan e al, Int J Cancer., 2013)

Ukuhlangana phakathi kweHip / Back Pain kanye neCancer yeBele neMetastasis

Ithambo yindawo evame kakhulu yomdlavuza webele we-metastasis noma ukusabalala. Ama-70% azo zonke iziguli ezinomdlavuza webele we-metastatic anethambo njengendawo ejwayelekile yomdlavuza esakazeka / i-metastasis engaholela ebuhlungwini bamathambo noma beqolo.

Umgogodla, izimbambo, ugebhezi, i-pelvis kanye namathambo angaphezulu ezingalo nemilenze kuvame ukuthinteka ngesikhathi somdlavuza webele. I-13.6% yeziguli ezinomdlavuza webele ezitholwe ngesikhathi sesigaba I-III zizoba ne-bone metastasis (ukusabalala kwe umdlavuza) eminyakeni eyi-15 yokulandelela. (UCaroline Goupille et al, Nutrients., 2020)

Ukungenelela Okungaba Nomsoco Okungenzeka Kwezinhlungu ze-Hip neBone ku-Cancer 

Okulandelayo yizibonelo zokudla / izengezo ezimbalwa ezethembisayo ezinganciphisa ubuhlungu bamalunga, okhalweni nobethambo ezigulini zomdlavuza.

I-Omega 3 Fatty Acids ingasiza ekunciphiseni i-Bone Metastasis ezigulini zomdlavuza webele

Ucwaningo olushicilelwe ngabaphenyi beCentre Hospitalier Régional Universitaire de Tours, eFrance luthole ukuthi amazinga aphansi e-omega-3 long-chain polyunsaturated fatty acids angahlotshaniswa ne-bone metastasis kubantu besifazane bangaphambi kokuya esikhathini abanomdlavuza webele. (UCaroline Goupille et al, Izakhi., 2020)

Ucwaningo lukhombisa ukuthi ukwengeza i-omega-3 fatty acids kungaba ukungenelela kokudla okunomsoco ukunciphisa i-bone metastasis (futhi mhlawumbe nomdlavuza wamathambo wesibili) ekugcineni kunciphise ubuhlungu bethambo ne-hip kwiziguli ezinomdlavuza, ikakhulukazi ezigulini zomdlavuza webele.

Ngokwengeziwe, ukusetshenziswa kwe-Omega 3 fatty acids kukhombisile ukunciphisa ubuhlungu obuhlangene bokuvuvukala ku-rheumatoid arthritis, ubuhlungu obungapheli bomgogodla kwizifo ezizimele kanye nobuhlungu be-neuropathic.

Imithombo Yokudla Ecebile eyi-Omega 3: Izinhlanzi ezinamafutha ezinjenge-salmon nokudla okususelwa ezitshalweni njengama-walnuts, uwoyela wemifino nembewu efana nembewu yeChia nembewu yefilakisi.

UVitamin D3 angasiza Ekunciphiseni Ubuhlungu Bemisipha Kwiziguli Ezinomdlavuza Webele

Ucwaningo olwenziwe ngabaphenyi abavela e-University of Nebraska Medical Center, eLincoln e-United States, iziguli ezinomdlavuza webele ezinamazinga aphansi ka-Vitamin D3 zibike ubuhlungu bamalunga nokuqina, ubuhlungu bamathambo nobuhlungu bemisipha entanyeni nasemhlane / okhalweni, ne ubuhlungu bukhula kakhulu ngamazinga anciphayo e-serum Vitamin D3. (UNancy L Waltman et al, Umhlengikazi Womdlavuza., Mar-Apr 2009)

Ucwaningo lukhombisa ukuthi ukwengeza i-Vitamin D3 kungaba ukungenelela kokudla okunempilo ukunciphisa izinhlungu ezihlangene nokuqina, ubuhlungu bamathambo nobuhlungu bemisipha entanyeni nasemuva ezigulini zomdlavuza, ikakhulukazi lezo ezinomdlavuza webele.

Imithombo Yokudla Ecebile ka-Vitamin D: Izinhlanzi ezinamafutha ezinjenge-salmon, i-tuna ne-mackerel, inyama, amaqanda, imikhiqizo yobisi, amakhowe.

ICurcumin ingaba namandla okuvimbela umdlavuza wamathambo futhi inciphise izinhlungu ezihlangene ezigulini zomdlavuza

ICurcumin iyisithako esiyinhloko esisebenzayo se-spice Turmeric.

Ucwaningo lokuhlola olwenziwe abacwaningi baseChina Medical University Hospital, eTaichung, eTaiwan bathola lokho Curcumin kungase kubangele i-apoptosis (ukufa kweseli) ye-chondrosarcoma yomuntu (umdlavuza oqala emathanjeni) imigqa yamaseli. (Hsiang-Ping Lee et al, Int Immunopharmacol., 2012)

Ngenxa yamandla okulwa nokuvuvukala nokulwa nomdlavuza weCurcumin, iCity of Hope Medical Center yenza ucwaningo lomtholampilo lokuphenya ukuthi isebenza kanjani kahle i-curcumin ekwehliseni ubuhlungu obuhlangene ezigulini ezisinde kumdlavuza webele futhi ezinezifo ezihlangene ezidalwa ukwelashwa i-aromatase inhibitors. (NCT03865992)

ICurcumin ingaba isengezo esithembisayo esinamandla okuvimbela umdlavuza wamathambo oyinhloko nasesekondari futhi sinciphise ubuhlungu obuhlangene ezigulini zomdlavuza.

I-Glucosamine kanye neChondroitin kungahle Kwehlise I-Aromatase Inhibitor Ebangelwa Ubuhlungu Joint Ezigulini Zomdlavuza Webele

Ucwaningo lwesigaba II olwenziwe yiColumbia University e-United States luhlolisise umthelela wokusebenzisa i-glucosamine-sulphate ne-chondroitin-sulfate amasonto angama-24 ebuhlungwini obuqinile / ekuqineni kwabesifazane abangemva kokuya esikhathini nabanomdlavuza webele wesigaba sokuqala ababa nobuhlungu obuhlanganyelwe obuqinile ngemuva kokuqala i-aromatase inhibitors. Ucwaningo luthole ukuthi ukwesekwa kwe-glucosamine / chondroitin kuholele ekuthuthukisweni okulinganiselayo kubuhlungu obuhlangene obenziwe nge-aromatase inhibitor kanye nokuqina, kube nemiphumela engemihle ezigulini zomdlavuza webele. (UHeather Greenlee et al, Umdlavuza Wokunakekela Ukusekela., 2013)

Isiphetho

Ubuhlungu okhalweni, ejoyintini, emhlane ongezansi noma ethanjeni kuwuphawu/uphawu/umphumela ovame kakhulu ezinhlotsheni zomdlavuza ezihlukene. Ukudla kanye nezithako ezihlanganisa i-Omega-3 fatty acids, i-Curcumin, i-Vitamin D3 ne-Glucosamine ene-Chondroitin ingase ibe namandla okunciphisa ubuhlungu be-musculoskeletal okuhlanganisa ubuhlungu bamalunga, i-hip, amathambo kanye nomgogodla ezigulini ezinomdlavuza, ikakhulukazi kumdlavuza webele. Izivivinyo zomtholampilo ezinkulu kufanele zenziwe ukuze kuqinisekiswe lokhu okutholakele. Gwema ngokungahleliwe ukuthatha lezi zithako ngaphandle kokuthintana nomhlinzeki wakho wezempilo ukuze ugweme noma yikuphi ukusebenzisana okungafuneki nokuqhubekayo umdlavuza ukwelashwa.

Ukudla okudlayo nokuthi yikuphi okunezelayo okwenzayo yisinqumo osithathayo. Isinqumo sakho kufanele sifake ukucutshungulwa kwezakhi zofuzo zomdlavuza, okuwumdlavuza, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imininingwane yokuphila, isisindo, ubude nemikhuba.

Ukuhlelela okunomsoco komdlavuza kusuka ku-addon akususelwa ekusesheni kwe-inthanethi. Kwenzela wena ukuthathela izinqumo ngokuya ngesayensi yamangqamuzana eyenziwe ososayensi bethu nonjiniyela be-software. Kungakhathalekile ukuthi ngabe uyakukhathalela ukuqonda okuyisisekelo kwamakhemikhali amakhemikhali noma cha - wokuhlelela umsoco ukuhlela lokho kudinga ukuqonda.

Qalisa MANJE ngokuhlela kwakho okunomsoco ngokuphendula imibuzo egameni lomdlavuza, ukuguquka kwezakhi zofuzo, ukwelashwa okuqhubekayo kanye nezithasiselo, noma yikuphi ukungezwani komzimba, imikhuba, indlela yokuphila, iqembu lobudala nobulili.

Iziguli ezinomdlavuza ngokuvamile kufanele zibhekane nokuhlukile imiphumela emibi ye-chemotherapy okuthinta ikhwalithi yempilo yabo futhi babheke ezinye izindlela zokwelapha umdlavuza. Ukuthatha ukudla okunomsoco nezithasiselo ezisuselwa ekucabangeni kwesayensi (ukugwema ukuqagela nokukhetha okungahleliwe) yikhambi elingcono kakhulu lemvelo lomdlavuza nemiphumela emibi ehlobene nokwelashwa.

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