Ngowuphi umhlaza onokuzuza ngokuquka i-Agaricus Mushroom ekutyeni kwabo?

Iimbalasane

I-Agaricus Mushroom yamkelwa ngokubanzi ngezibonelelo zayo zempilo kwaye isetyenziswa rhoqo zizigulana ezinomhlaza kunye nezo zisengozini yemfuzo. Nangona kunjalo, ukhuseleko kunye nokusebenza kwe-Agaricus Mushroom kwizigulana ezinomhlaza kuxhomekeke kwizinto ezininzi ezifana nesalathiso somhlaza, ichemotherapy, olunye unyango, kunye nemfuzo yethumba. Ukwazi ukuba ezinye ukutya kunye nezongezelelo, ezinje ngegrapefruit kunye nesipinatshi, zinokusebenzisana kakubi namayeza omhlaza kwaye zibangele ukusabela okubi kubalulekile.

Ukutya kubaluleke kakhulu kunyango lomhlaza njengoko kunokuchaphazela iziphumo zonyango. Izigulana ezinomhlaza kufuneka zikhethe ngononophelo kwaye zifake ukutya okufanelekileyo kunye nezongezo kwizidlo zabo. Umzekelo, i-Agaricus Mushroom inokuba luncedo kwabo banePrayimari yePenile Squamous Cell Carcinoma ephantsi kweMitomycin, kodwa isenokungabi ilungile kwizigulana ezifumana iRadiation yePrimary Sclerosing Epithelioid Fibrosarcoma. Ngaphaya koko, ngexa i-Agaricus Mushroom inokunceda abantu abane-genetic risk factor "CDKN2A", ayinakucetyiswa kwabo banobungozi bofuzo obahlukileyo "KMT2D". Ukwenza izicwangciso zokutya ezisekelwe kwimpilo, unyango, kunye nofuzo kubalulekile.

Ukuqonda ukuba ukwenza isigqibo malunga nokufaneleka kwe-Agaricus Mushroom kwisigulana somhlaza kufuneka kube ngumntu ngamnye kubalulekile. Imiba ebalulekileyo njengodidi lomhlaza, iindlela zonyango, ukwakheka kwemfuzo, imingcipheko yemfuza, ubudala, ubunzima bomzimba, kunye nendlela yokuphila zibalulekile ekuthatheni isigqibo sokuba i-Agaricus Mushroom lolona khetho lufanelekileyo. I-Genomics kunye ne-genomics, ngokukodwa, yingqwalasela ebalulekileyo. Kuba ezi zinto zinokuvela, kubalulekile ukuphonononga rhoqo kwaye ulungelelanise ukhetho lokutya ukuhambelana notshintsho kwisimo sempilo kunye nonyango.

Ukuqukumbela, indlela epheleleyo yokhetho lokutya ibalulekile, ijolise kwiziphumo ezipheleleyo zazo zonke iinxalenye ezisebenzayo ekutyeni / izongezo ezifana ne-Agaricus Mushroom endaweni yokuvavanya isithako ngasinye esisebenzayo ngokwahlukileyo okanye ukungayinaki ngokupheleleyo. Lo mbono ubanzi ukhuthaza indlela enengqiqo nenzululwazi kwisicwangciso sokutya somhlaza.

Uluhlu olufutshane

Ukusetyenziswa kokutya okusekelwe kwizityalo kunye nezongezelelo, ezinje ngeevithamini, imifuno, iiminerali, iiprobiotics, kunye nezongezelelo ezahlukeneyo ezikhethekileyo, ziyenyuka phakathi kwabaguli abanomhlaza. Ezi zongezo ziyilelwe ukuhambisa ugxininiso oluphezulu lwezithako ezithile ezisebenzayo, uninzi lwazo zikwakukutya okwahlukeneyo. Ugxininiso kunye nokwahlukana kwezithako ezisebenzayo ziyahluka phakathi kokutya okupheleleyo kunye nezongezelelo. Ukutya ngokuqhelekileyo kunika uluhlu lwezithako ezisebenzayo kodwa kwiindawo ezisezantsi, ngelixa izongezelelo zibonelela ngoxinzelelo oluphezulu lwezithako ezithile.

Ukuthathela ingqalelo imisebenzi eyahlukeneyo yesayensi kunye neyebhayoloji yesithako ngasinye esisebenzayo kwinqanaba leemolekyuli, kubalulekile ukunika ingxelo ngeziphumo ezidityanisiweyo zala malungu xa uthatha isigqibo malunga nokutya kunye nezongezo eziza kutyiwa okanye hayi.

Umbuzo obalulekileyo ovelayo: Ngaba kufuneka udibanise i-Agaricus Mushroom kwisidlo sakho njengento yokutya okanye isongezelelo? Ngaba kuyacetyiswa ukuba utye i-Agaricus Mushroom ukuba une-genetic predisposition to cancer edibene ne-CDKN2A gene? Kuthekani ukuba endaweni yoko umngcipheko wakho wemfuza usuka kumfuza we-KMT2D? Ngaba kunenzuzo ukuquka i-Agaricus Mushroom ekutyeni kwakho ukuba ufunyaniswe unePrimary Sclerosing Epithelioid Fibrosarcoma, okanye ukuba uxilongo lwakho yiPrimary Penile Squamous Cell Carcinoma? Ngaphezu koko, kufuneka kuhlengahlengiswe njani ukusela kwakho i-Agaricus Mushroom ukuba ufumana unyango lwe-Mitomycin okanye ukuba isicwangciso sakho sonyango siyatshintsha sisuka kwi-Mitomycin siye kwiRadiation? Kubalulekile ukuqonda ukuba iintetho ezilula ezifana 'neAgaricus Mushroom yindalo, ngoko ke isoloko iluncedo' okanye 'I-Agaricus Mushroom yomeleza ukhuselo lomzimba' akonelanga kukhetho lokutya/ lokongezelela.

Ukongeza, kubalulekile ukuvavanya kwakhona ukufaneleka kokubandakanya i-Agaricus Mushroom kwisidlo sakho ukuba kukho utshintsho kwirejimeni yonyango lwakho. Isishwankathelo, xa usenza izigqibo malunga nokubandakanya ukutya okanye izongezo ezifana ne-Agaricus Mushroom kwisidlo sakho ngenxa yezibonelelo zayo, kuya kufuneka uqwalasele iziphumo ezipheleleyo ze-biochemical yazo zonke izithako, uqwalasela izinto ezifana nohlobo lomhlaza, unyango oluthile olwenzayo, imfuzo. izinto ezilindelekileyo, kunye nokukhetha indlela yokuphila.

Cancer

Umhlaza usengumceli mngeni obalulekileyo kwicandelo lezonyango, ngokufuthi ubangela unxunguphalo oluxhaphakileyo. Nangona kunjalo, ukuqhubela phambili kwamva nje kuye kwaphucula iziphumo zonyango, ngakumbi ngeendlela zonyango zomntu, iindlela zokujonga ezingaphazamisiyo kusetyenziswa igazi kunye neesampulu zamathe, kunye nophuhliso lwe-immunotherapy. Ukufunyaniswa kwangethuba kunye nokungenelela kwangethuba kuye kwaba yinto ebalulekileyo ekuphembeleleni ngokufanelekileyo iziphumo zonyango ngokubanzi.

Uvavanyo lwemfuzo lunikeza isithembiso esibalulekileyo ekuvavanyeni umngcipheko womhlaza kunye nokuba sesichengeni kwangoko. Nangona kunjalo, kubantu abaninzi abaneemeko zosapho kunye nemfuzo kumhlaza, ukhetho longenelelo lonyango, nokuba lubekwe esweni rhoqo, luhlala lulinganiselwe okanye alukho. Emva kokuba ufumene uhlobo oluthile lomhlaza, njenge-Primary Penile Squamous Cell Carcinoma okanye i-Primary Sclerosing Epithelioid Fibrosarcoma, izicwangciso zonyango kufuneka zenziwe ngokwezifiso ngokusekelwe kwi-tumor genetics yomntu, isigaba sesifo, kunye nezinto ezifana nobudala kunye nesini. ”

Emva konyango, ukubeka iliso okuqhubekayo kubalulekile ukuze kubonwe naziphi na iimpawu zokubuyela kwakhona komhlaza kunye nokwazisa izigqibo ezilandelayo. Uninzi lwezigulana ezinomhlaza kunye nabo basemngciphekweni bahlala befuna iingcebiso malunga nokubandakanya ukutya okuthile kunye nezongezo kwizidlo zabo, ezidlala indima ebalulekileyo kwinkqubo yabo yokuthatha isigqibo malunga nolawulo lwezempilo.

Umbuzo obalulekileyo ngowokuba ingaba kubandakanyeke kwimingcipheko yemfuza kunye noxilongo oluthile lomhlaza xa uthatha isigqibo malunga nokhetho lokutya, olufana ne-Agaricus Mushroom. Ngaba umngcipheko wemfuzo womhlaza osuka kutshintsho kwi-CDKN2A uneempembelelo zendlela yebhayoloji efanayo njengotshintsho kwi-KMT2D? Ukusuka kwimbono yesondlo, ngaba umngcipheko ohambelana nePrayimari yePenile Squamous Cell Carcinoma ilingana nePrimary Sclerosing Epithelioid Fibrosarcoma? Ngaphaya koko, ngaba uqwalaselo lokutya luhlala lufana kwabo baphantsi kweRadiation njengabo bafumana iMitomycin? Ezi ngqwalasela zibalulekile ekwenzeni ukhetho lokutya olunolwazi lwabantu abaneengozi ezahlukeneyo zemfuza kunye nonyango lomhlaza.

I-Agaricus Mushroom-Isongezelelo seZondlo

I-Agaricus Mushroom eyongezelelweyo ibandakanya uluhlu lwezithako ezisebenzayo, ezibandakanya i-Vitamin E, i-Ergosterol, i-Vitamin B3, i-Vitamin C kunye ne-Linoleic Acid, nganye ekhoyo kwiimpawu ezahlukeneyo. Ezi zithako zinefuthe kwiindlela ze-molekyuli, ngokukodwa i-Cell Cycle Checkpoints, i-TGFB Signaling, i-Growth Factor Signaling kunye ne-MAPK Signaling, elawula imiba ebalulekileyo yomhlaza kwinqanaba leeselula, ezifana nokukhula kwe-tumor, ukusasazeka, kunye nokufa kweeseli. Ukunikezelwa kwale mpembelelo yebhayoloji, ukukhetha izongezo ezifanelekileyo njenge-Agaricus Mushroom, iyodwa okanye ngokudibeneyo, iba sisigqibo esibalulekileyo kumxholo wesondlo somhlaza. Xa ucinga ukusebenzisa i-Agaricus Mushroom yomhlaza, kubalulekile ukuqwalasela ezi zinto zahlukeneyo kunye neendlela. Oku kungenxa yokuba, ngokufanayo nonyango lomhlaza, ukusetyenziswa kwe-Agaricus Mushroom ayisosigqibo sehlabathi lonke esifanelekileyo kuwo onke ama-cancer kodwa kufuneka ibe yeyomntu.

Ukukhetha iAgaricus Mushroom Supplements

Ukuphendula umbuzo othi 'Ndingaliphepha nini i-Agaricus Mushroom kwimeko yoMhlaza' kulucelomngeni kuba impendulo yeyomntu ngamnye kakhulu - ngokulula 'Kuxhomekeke!'. Ngokufana nendlela naluphi na unyango lomhlaza olunokuthi lungasebenzi kwisigulana ngasinye, ukubaluleka kunye nokhuseleko okanye iinzuzo ze-Agaricus Mushroom ziyohluka ngokuxhomekeke kwiimeko zomntu. Izinto ezifana nohlobo oluthile lomhlaza, i-genetic predispositions, unyango lwangoku, ezinye izongezo ezithathwayo, iindlela zokuphila, i-BMI, kunye naluphi na uhlobo oluthile lomzimba, zonke zidlala indima ekuqinisekiseni ukuba i-Agaricus Mushroom ifanelekile okanye kufuneka igwenywe, igxininisa ukubaluleka koqwalaselo lomntu. kwizigqibo ezinjalo.

1. Ingaba iAgaricus Mushroom Supplements izakuxhamla iPrimary Sclerosing Epithelioid Fibrosarcoma Izigulana eziphantsi konyango lweRadiation?

I-Primary Sclerosing Epithelioid Fibrosarcoma ibonakaliswe ngokuguqulwa kofuzo oluthile, oko kukuthi, i-PBRM1, i-ATRX kunye ne-PIK3C2G, ekhokelela ekutshintsheni kwiindlela ze-biochemical, ngokukodwa i-TGFB yoMbonakaliso kunye ne-Inositol Phosphate Signaling. Ukusebenza konyango lomhlaza, njengeRadiation, kuxhomekeke kwindlela yokusebenza kwezi ndlela zikhethekileyo. Esona sicwangciso sifanelekileyo siquka ukulungelelanisa isenzo sonyango kunye neendlela eziqhuba umhlaza, ngaloo ndlela kuqinisekiswa indlela yobuqu nesebenzayo. Kwiimeko ezinjalo, ukuphepha ukutya okanye izongezo zesondlo ezinokuchasa iziphumo zonyango okanye ukunciphisa olu lungelelwaniso kubalulekile. Ngokomzekelo, i-Agaricus Mushroom supplement, echaphazela i-TGFB Signaling, isenokungabi yinto efanelekileyo yokuzikhethela kwimeko ye-Primary Sclerosing Epithelioid Fibrosarcoma xa i-Radiation. Oku kungenxa yokuba isenokuthi iqhubele phambili ngakumbi isifo okanye iphazamise ukusebenza konyango. Xa ukhetha isicwangciso sesondlo, kubalulekile ukuqwalasela izinto ezifana nohlobo lomhlaza, unyango oluqhubekayo, ubudala, isini, i-BMI, indlela yokuphila, kunye naluphi na utshintsho lwemfuza olwaziwayo.

2. Ingaba izongezo ze-Mushroom ze-Agaricus ziya kuxhamla kwiZigulana eziphantsi kwe-Penile Squamous Cell Carcinoma eziphantsi koNyango lwe-Mitomycin?

I-Primary Penile Squamous Cell Carcinoma ichongiwe ngeenguqu ezithile zofuzo, ezifana ne-ABRAXAS1, i-PIK3CB kunye ne-NUP93, ebangela utshintsho kwiindlela ze-biochemical pathways, ngokukodwa i-Cell Cycle Checkpoints, i-Hematopoiesis kunye ne-Inositol Phosphate Signaling. Ukusebenza konyango lomhlaza, njengeMitomycin, kumiselwa kukudibana kwayo nezi ndlela. Injongo kukuqinisekisa ukuba unyango luhambelana kakuhle neendlela eziqhuba umhlaza, okwenza kube nendlela yonyango lomntu. Kulo mxholo, ukutya okanye izongezo ezihambelana nonyango okanye ukuphucula oku kulungelelaniswa kufuneka kuthathelwe ingqalelo. Ngokomzekelo, i-Agaricus Mushroom isongezelelo lukhetho olunengqiqo kulabo abanePrayimari yePenile Squamous Cell Carcinoma ehamba neMitomycin. Oku kungenxa yokuba i-Agaricus Mushroom inefuthe kwiindlela ezinje ngeCell Cycle Checkpoints, ezinokuthi zithintele izinto eziqhuba iPrimary Penile Squamous Cell Carcinoma okanye zizuze ukusebenza kweMitomycin.

3. Ingaba iAgaricus Mushroom Supplements ikhuselekile kuBantu abasempilweni abane-KMT2D Uguquko oluNxulunyaniswe neMngcipheko yeMfuzo?

Iinkampani ezahlukeneyo zibonelela ngeephaneli zemfuza zokuvavanya umngcipheko wemfuza weentlobo ezahlukeneyo zomhlaza. Ezi panels ziquka imizila yemfuza enxulunyaniswa nebele, i-ovarian, i-uterine, i-prostate, kunye nomhlaza wesisu. Ukuvavanya ezi genes kunokuqinisekisa ukuxilongwa kunye nokwazisa unyango kunye nezicwangciso zokulawula. Ukuchonga umahluko obangela isifo kunokuncedisa ngakumbi ekuvavanyeni nasekuxilongweni kwezalamane ezinokuba sengozini. Ufuzo lwe-KMT2D luqhele ukubandakanywa kwezi panels zovavanyo lomngcipheko womhlaza.

Ukuguqulwa kwe-gene ye-KMT2D kuchaphazela iindlela ze-biochemical okanye iinkqubo, ezifana ne-Growth Factor Signaling kunye ne-Oncogenic Histone Methylation, ebandakanyeka ngokuthe ngqo okanye ngokungathanga ngqo ekuqhubeni umhlaza kwinqanaba le-molecular. Xa iphaneli yofuzo ichonga utshintsho kwi-KMT2D ehambelana nomngcipheko owongeziweyo we-Bladder Urothelial Carcinoma, ingqiqo yenzululwazi icebisa ukuphepha ukusetyenziswa kwe-Agaricus Mushroom. Oku kungenxa yokuba ukongeza i-Agaricus Mushroom inefuthe kwiindlela ezifana ne-Growth Factor Signaling, enokukhokelela kwimiphumo emibi kumxholo wenguqu ye-KMT2D kunye neemeko zomhlaza ezinxulumene nazo.

4. Ingaba iAgaricus Mushroom Supplements ikhuselekile kuBantu abasempilweni abaneCDKN2A Mutation Associated Genetic Risk?

I-CDKN2A idlala indima ebalulekileyo kuvavanyo lomngcipheko womhlaza. Ukuguqulwa kwe-CDKN2A kunokuphazamisa iindlela ezibalulekileyo ze-biochemical, kuquka i-MAPK Signaling, i-Cell Cycle Checkpoints kunye ne-Cell Cycle, echaphazela ukuphuhliswa komhlaza. Ukuba iphaneli yakho yemfuza ityhila utshintsho kwi-CDKN2A ehambelana noMhlaza woLusu, cinga ngokubandakanya izongezo ze-Agaricus Mushroom kwisicwangciso sakho sesondlo. Ezi zongezo zinokuphembelela ngendlela eyiyo iindlela ezifana ne-MAPK yokuSayina, inzuzo ngokubonelela ngenkxaso efanelekileyo kubantu abaneenguqu ze-CDKN2A kunye neenkxalabo zempilo ezinxulumeneyo.

Ukuququmbela

Ezona zinto zimbini zibalulekileyo ekufuneka uzikhumbule kukuba unyango lomhlaza kunye nesondlo azinakuze zifane kumntu wonke. Isondlo, kubandakanywa ukutya kunye nezongezo ezifana ne-Agaricus Mushroom, sisixhobo esisebenzayo esinokulawulwa nguwe ngelixa ujongene nomhlaza.

"Ndingatya ntoni?" ngowona mbuzo udla ngokubuzwa ngabaguli abanomhlaza kunye nabo basemngciphekweni womhlaza. Impendulo echanekileyo kukuba ixhomekeke kwizinto ezifana nohlobo lomhlaza, imfuzo yethumba, unyango lwangoku, ukungezwani komzimba, indlela yokuphila, kunye ne-BMI.

Fumana isondlo sakho somhlaza kwi-addon ngokucofa ikhonkco elingezantsi kwaye uphendule imibuzo malunga nohlobo lomhlaza wakho, unyango, indlela yokuphila, i-allergies, ubudala, kunye nesini.

Ucaphulo

• Ukusetyenziswa kwe-PPAR gamma kunye ne-delta nge-conjugated linoleic acid ilamla ukhuseleko kwisifo sesibindi sokudumba.
• Iiseti ezichazwe ngokwemfuza zomhlaza wepancreatic womntu zibonisa eyodwa kwi-vitro chemosensitivity.
• cBioPortal for Cancer Genomics
• Ukwandiswa kwempendulo ye-glutamate ngeprotein kinase exhomekeke kwi-cAMP kwi-hippocampal neurons.
• Ukuphanda inhibition yokufuduka kunye neziphumo ze-apoptotic ze-Fomitopsis pinicola chloroform isicatshulwa kumhlaza womhlaza we-colorectal SW-480 iiseli.
• Unyango lomhlaza lubumba ubume bokuqina be-clonal hematopoiesis.
• Ukumelana nonomathotholo kwiiseli zomhlaza webele kulamlwa nge-TGF-β yokubonisa, i-hybrid epithelial-mesenchymal phenotype kunye neeseli ze-cancer stem.
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• Indima ye-phospholipase D ekufudukeni kunye nokuhlasela okubangelwa yi-linoleic acid kwiiseli zomhlaza webele.