Ukutya kwePrayimari yeNervous System Lymphoma!

intshayelelo

Ukutya kuMbindi weNervous System Lymphoma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Primary central nervous system lymphoma (PCNSL) luhlobo lwe-non-Hodgkin lymphoma echaphazela ngokukodwa inkqubo ye-nervous central. Ukuxilongwa ngokuchanekileyo kunye nokumisela i-prognosis ye-PCNSL kubalulekile ekuphuhliseni isicwangciso sonyango. Izinga lokusinda kwi-PCNSL liyahluka ngokuxhomekeka kwizinto ezahlukeneyo, ezifana nesiteji kunye ne-subtype ye-lymphoma. Ikhowudi ye-ICD-10 efanelekileyo iqinisekisa ikhowudi yonyango efanelekileyo kunye namaxwebhu. I-PCNSL ihluke kwi-systemic lymphomas njengoko ibandakanya ngokukodwa inkqubo ye-nervous central. Iindlela ezahlukeneyo zokucinga, ezinje nge-imaging resonance magnetic (MRI), zidlala indima ebalulekileyo ekuxilongeni i-PCNSL kunye nokuchonga iimpawu zayo. Usulelo lwe-HIV lunokubangela ukuba umntu abe ne-PCNSL. Ukuxilongwa kwe-PCNSL kufuna uvavanyo olubanzi, kubandakanywa ne-biopsy kunye nohlalutyo lwe-histopathological. I-National Comprehensive Cancer Network (NCCN) ibonelela ngezikhokelo zolawulo lwe-PCNSL. Iimpawu ze-PCNSL zinokubonwa kwizifundo ze-radiological. Ukuqonda i-epidemiology kunye nokunikezelwa kweklinikhi ye-PCNSL kubalulekile ekubhaqweni kwangaphambili kunye nolawulo olufanelekileyo. Ngokuhlala unolwazi kunye nokusebenza ngokusondeleyo kunye nabasebenzi bezempilo, abantu abane-PCNSL banokuphucula iziphumo zabo zonke kwaye bafumane unyango olufanelekileyo.

KwiSixokelelwano esiPhambili seNervous yeLymphoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, iindongomane, iimbewu umntu azityayo?

Umbuzo oxhaphake kakhulu ngesondlo obubuzwa zizigulane ezinomhlaza kunye nabantu abakumngcipheko wemfuzo womhlaza ngowomhlaza - kwimihlaza efana nePrimary Central Nervous System Lymphoma ingaba iyabaluleka na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba oko kwanele kumhlaza onje ngePrimary Central Nervous System Lymphoma?

Umzekelo ingaba inomsebenzi ukuba imifuno iMushroom eqhelekileyo ityiwa kakhulu xa kuthelekiswa neSwede? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyakhethwa kuneCranberry yaseYurophu? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut ngaphezu kweCashew Nut kunye nezityalo ezifana neBroad Bean phezu kweLentils. Kwaye ukuba into endiyityayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Primary Central Nervous System Lymphoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Primary Central Nervous System Lymphoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo Apigenin, Curcumin, Quercetin, Lycopene, Naringin. Kwaye i-Cranberry yaseYurophu iqulethe izithako ezisebenzayo Apigenin, Curcumin, Quercetin, Lycopene, Ellagic Acid kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Primary Central Nervous System Lymphoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo kwi-Primary Central Nervous System Lymphoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Primary Central Nervous System Lymphoma?

Izondlo zomntu zomhlaza ezifana nePrimary Central Nervous System Lymphoma ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Primary Central Nervous System Lymphoma biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle indlela unyango lomhlaza olusebenza ngayo kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana nePrimary Central Nervous System Lymphoma

Zonke ii-cancer ezifana ne-Primary Central Nervous System Lymphoma inokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Primary Central Nervous System Lymphoma. Iindlela ze-Biochemical ezifana ne-Apoptosis, i-MAPK Signaling, i-NFKB Signaling, i-Focal Adhesion iyingxenye yenkcazo yesiginesha ye-Primary Central Nervous System Lymphoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Primary Central Nervous System Lymphoma kufuneka ithathelwe ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulane ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwiPrimary Central Nervous System Lymphoma xa uthatha unyango lomhlaza i-Epirubicin, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-MYD88, i-PIM1, i-CD79B, i-FAT4 kunye ne-TCL1A zezona ntlobo zemfuza ezixeliweyo eziphezulu kwi-Primary Central Nervous System Lymphoma. I-MYD88 ixelwe kwi-70.0 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-PIM1 ichazwe kwi-40.0%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-54 ukuya kuma-83. Ama-44.4 % edatha yezigulane ichongwe njengamadoda. I-Primary Central Nervous System Lymphoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela ze-biochemical kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo zeSistim yeNervous ePhambili yeLymphoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable MUSHROOM EQHELEKILEYO okanye iSWEDE?

I-Vegetable Common Mushroom iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Luteolin, i-Daidzein, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA, uMjikelo weSeli, umqondiso we-MAPK kunye nokusinda kweeseli kunye nabanye. I-Common Mushroom iyacetyiswa kwi-Primary Central Nervous System Lymphoma xa unyango lomhlaza oluqhubekayo i-Epirubicin. Oku kungenxa yokuba i-Common Mushroom iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zenze impembelelo ye-Epirubicin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseSweden yi-Apigenin, i-Curcumin, i-Daidzein, i-Phloretin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye noxinzelelo lwe-Oxidative kunye nezinye. I-Swede ayikhuthazwa kwi-Primary Central Nervous System Lymphoma xa unyango lomhlaza oluqhubekayo yi-Epirubicin kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IKHOWA ELIQHELEKILEYO ELIQHELEKILEYO IYANCEBISWA PHEZU KWESWEDE KWIPrayimari yeNervous System Lymphoma KUNYE NONYANGO I-Epirubicin.

Khetha iSiqhamo eYurophu CRANBERRY okanye iPUMMELO?

Isiqhamo seCranberry yaseYurophu iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Ellagic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA, uMjikelo weSeli, umqondiso we-MAPK kunye nokusinda kweeseli kunye nabanye. I-Cranberry yaseYurophu icetyiswa kwi-Primary Central Nervous System Lymphoma xa unyango lomhlaza oluqhubekayo yi-Epirubicin. Oku kungenxa yokuba i-Cranberry yaseYurophu iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zikhuthaze umphumo we-Epirubicin.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Naringin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Glutathione Metabolism kunye nabanye. IPummelo ayikhuthazwa kwiPrimary Central Nervous System Lymphoma xa unyango lomhlaza oluqhubekayo i-Epirubicin kuba lulungisa ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO SEKRANBERRY YASEYUROYA IYAKUCEBISWA NGAPHEZU KWE-PUMMELO KWI-Primary Central Nervous System Lymphoma KUNYE NONYANGO I-Epirubicin.

Khetha i-Nutt BUTTERNUT okanye i-CASHEW NUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lycopene, i-Luteolin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA, uMjikelo weSeli, umqondiso we-MAPK kunye nokusinda kweeseli kunye nabanye. I-Butternut icetyiswa kwi-Primary Central Nervous System Lymphoma xa unyango lomhlaza oluqhubekayo i-Epirubicin. Oku kungenxa yokuba iButternut ilungisa ezo ndlela zebhayochemicals ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Epirubicin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Cashew Nut yi-Curcumin, i-Quercetin, i-Daidzein, i-Phloretin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-Oxidative Stress kunye ne-MYC Signaling kunye nezinye. I-Cashew Nut ayikhuthazwa kwi-Primary Central Nervous System Lymphoma xa unyango lomhlaza oluqhubekayo i-Epirubicin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

IBHUTTERNUT IYAYINGCEBISWA NGAPHEZU KWE-CASHEW UT FOR Primary Central Nervous System Lymphoma KUNYE NONYANGO IEpirubicin.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza ye-Primary Central Nervous System Lymphoma okanye imbali yentsapho "Yintoni endimele ndiyidle ngokwahlukileyo ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha i-anyanisi yemifuno yegadi okanye i-GROUNDCHERRY?

I-anyanisi yaseGadini yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-P53 Signaling, i-B Cell Receptor Signaling, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nabanye. I-Garden Onion icetyiswa kumngcipheko we-Primary Central Nervous System Lymphoma xa umngcipheko wezofuzo uhambelana ne-CD79B. Oku kungenxa yokuba iGarden Onion yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeGroundcherry yi-Apigenin, Curcumin, Lycopene, Formononetin, Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Extracellular Matrix Remodeling kunye ne-NFKB Signaling kunye nezinye. IGroundcherry ayikhuthazwa xa umngcipheko wePrimary Central Nervous System Lymphoma xa umngcipheko wezofuzo unxulumene ne-CD79B kuba yonyusa iindlela zokutyikitya kuyo.

Itswele LEGADI YEMIFUNO KUCEBISWA NGAPHEZU KWEGROUNCERRY KWI-CD79B genetic RISK YOMHLAZA.

Khetha iFruit BILBERRY okanye IMBEWU YOMTHI YEBREADNUT?

I-Fruit Bilberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Resveratrol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-P53 Signaling, i-NFKB yokuSayina kunye ne-MYC Signaling kunye nabanye. I-Bilberry icetyiswa kumngcipheko we-Primary Central Nervous System Lymphoma xa ingozi yemfuzo ehambelana nayo yi-CD79B. Oku kungenxa yokuba iBilberry yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo Imbewu ye-Breadnut Tree yi-Apigenin, i-Curcumin, i-Lycopene, i-Formononetin, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Extracellular Matrix Remodeling kunye ne-NFKB Signaling kunye nezinye. Imbewu ye-Breadnut Tree ayikhuthazwa xa umngcipheko we-Primary Central Nervous System Lymphoma xa umngcipheko wezofuzo uhambelana ne-CD79B kuba yonyusa iindlela zokutyikitya.

I-FRUIT BILBERRY IYAYINGCEBISWA NGAPHEZU KWEMBEWU YOMTHI YEBREADNUT NGE-CD79B genetic RISK YOMHLAZA.

Khetha i-Nutt EQHELEKILEYO WALNUT okanye iWALNUT YASEJAPANE?

I-Walnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Formononetin, i-Beta-sitosterol, i-Psoralen. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-NFKB Signaling, i-P53 Signaling, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nabanye. I-Walnut eqhelekileyo icetyiswa kumngcipheko we-Primary Central Nervous System Lymphoma xa umngcipheko wemfuzo ohambelana ne-CD79B. Oku kungenxa yokuba iWalnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Walnut yaseJapan yi-Apigenin, i-Curcumin, i-Lycopene, i-Formononetin, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Extracellular Matrix Remodeling kunye ne-NFKB Signaling kunye nezinye. IWalnut yaseJapan ayinconywa xa umngcipheko wePrimary Central Nervous System Lymphoma xa umngcipheko wezofuzo unxulunyaniswa ne-CD79B kuba yonyusa iindlela zokutyikitya kuyo.

IWALNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWEWALNUT YASEJAPANE NGE-CD79B YOMNGCIPHEKO WEMFUZO YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana nePrimary Central Nervous System Lymphoma. I-Primary Central Nervous System izigulane zeLymphoma kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana nePrimary Central Nervous System Lymphoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Common Mushroom kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Primary Central Nervous System Lymphoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Pcnsl May 2015
• I-Daidzein yenza umsebenzi wokulwa ne-tumor ngokuchasene neeseli zomhlaza wesinyi ngokunqanda indlela ye-FGFR3.
• I-Myricetin ibangela i-apoptosis ngokuvimbela i-P21 i-activated kinase 1 (PAK1) i-cascade yomqondiso kwi-hepatocellular carcinoma.
• Indlela yemolekyuli ye-luteolin-induced apoptosis inokunxulumana nokuthintelwa kwe-angiogenesis kwiiseli ze-pancreatic carcinoma zabantu.
• I-Protocatechuic acid inqanda ukukhula kweeseli zomhlaza we-ovarian ngokubangela i-apoptosis kunye ne-autophagy.