Ukutya kwePancreatic Neuroendocrine Tumor!

intshayelelo

Ukutya kwePancreatic Neuroendocrine Tumor kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-pancreatic neuroendocrine tumor (PNET) luhlobo olunqabileyo lomhlaza ovela kwiiseli ze-neuroendocrine kwi-pancreas. Ukubhalwa kwekhowudi okuchanekileyo kunye namaxwebhu e-PNET aququzelelwa yinkqubo yokuhlelwa kwe-ICD-10. Iradiyoloji idlala indima ebalulekileyo ekubhaqweni nasekubekeni i-PNET, ngelixa i-pathology ichaza uncedo ekuqondeni iimpawu kunye neempawu zeli thumba. Ubomi obulindelekileyo kwi-pancreatic neuroendocrine tumors iyahluka ngokuxhomekeke kwizinto ezahlukeneyo ezifana nenqanaba kunye nobundlongondlongo bomhlaza. Ukuqaphela iimpawu ze-PNET kubalulekile ukuxilongwa ngexesha elifanelekileyo, elinokubandakanya intlungu yesisu, ukulahlekelwa kwesisindo, kunye nokungalingani kwehomoni. Amazinga okusinda kwi-pancreatic neuroendocrine tumors ixhomekeke kwinqanaba lokuxilongwa kunye nokusebenza kakuhle kwonyango. Iinketho zonyango ze-PNET zinokubandakanya utyando, unyango lwemitha, ichemotherapy, kunye nonyango olujoliswe kuyo. Iindidi ezahlukeneyo ze-PNET zingenzeka, kubandakanywa nezo zihambelana ne-multiple endocrine neoplasia uhlobo lwe-1 (MEN1). Ulawulo lwe-pancreatic neuroendocrine tumors ludinga indlela ye-multidisciplinary kunye nokuthobela izikhokelo zonyango. Ukuxilongwa kwe-PNET kubandakanya indibaniselwano yokucinga, i-biopsy, kunye nohlalutyo lweempawu zethumba. Unyango lwemichiza, olufana nokusebenzisa i-sunitinib, lunokuqeshwa kwiimeko eziphambili okanye ezingenakuchaswa. Ukuqonda nokulawula i-PNET kubalulekile ekuphuculeni iziphumo zezigulane kunye nomgangatho wobomi.

KwiPancreatic Neuroendocrine Tumor ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu wesondlo obubuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza we-cancer onje ngePancreatic Neuroendocrine Tumor ingaba ayinamsebenzi ukuba kukutya ntoni na endikutyileyo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngePancreatic Neuroendocrine Tumor?

Umzekelo ingaba inomsebenzi ukuba imifuno yeButterbur ityiwa kakhulu xa ithelekiswa neBrokholi yaseTshayina? Ngaba kuyawenza umahluko ukuba isiqhamo seStrobheli seGuava sikhethwa ngaphezu kweRed raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neButternut ngaphezu kweChestnut yaseYurophu kunye nemifuno efana neGram Bean phezu kwePigeon Pea. Kwaye ukuba into endiyityayo ibalulekile - ke umntu uchonga njani ukutya okucetyiswayo kwi-Pancreatic Neuroendocrine Tumor kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo imiba yePancreatic Neuroendocrine Tumor!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo I-Strawberry Guava iqulethe izithako ezisebenzayo i-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Lycopene. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Phloretin kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Pancreatic Neuroendocrine Tumor - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo sePancreatic Neuroendocrine Tumor.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kwiSondlo soMntu kwiPancreatic Neuroendocrine Tumor?

Izondlo zomntu zomhlaza ezifana nePancreatic Neuroendocrine Tumor ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Pancreatic Neuroendocrine Tumor biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana nePancreatic Neuroendocrine Tumor

Zonke i-cancer ezifana ne-Pancreatic Neuroendocrine Tumor inokubonakaliswa ngeseti ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya zePancreatic Neuroendocrine Tumor. Iindlela ze-Biochemical ezifana ne-Apoptosis, i-RAS-RAF Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Cell Cycle iyingxenye yenkcazo yesignesha ye-Pancreatic Neuroendocrine Tumor. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Pancreatic Neuroendocrine Tumor kufuneka ithathelwe ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwi-Pancreatic Neuroendocrine Tumor xa uthatha unyango lomhlaza i-Sunitinib, kunye nokunye ukutya kunye nezongezelelo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-MEN1, i-TP53, i-KRAS, i-DYNC1I1 kunye ne-KMT2A zezona ziphezulu iijene ezixeliweyo ze-Pancreatic Neuroendocrine Tumor. I-MEN1 ixelwe kwi-3.3% yezigulane ezimele kuzo zonke iimvavanyo zeklinikhi. Kwaye i-TP53 ichazwe kwi-2.1%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kwi-17 ukuya kuma-87. I-55.2 % yedatha yesigulane ichongwa njengamadoda. I-Pancreatic Neuroendocrine Tumor biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo zePancreatic Neuroendocrine Tumor

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR or CHINESE BROCCOLI?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Formononetin, i-Lycopene, i-Phloretin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Epithelial ukuya kwi-Mesenchymal Transition, i-Angiogenesis kunye ne-Focal Adhesion kunye nabanye. I-Giant Butterbur iyacetyiswa kwi-Pancreatic Neuroendocrine Tumor xa unyango oluqhubekayo lomhlaza yi-Sunitinib. Oku kungenxa yokuba i-Giant Butterbur iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Sunitinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Broccoli yaseTshayina yi-Curcumin, i-Formononetin, i-Phloretin, i-Lupeol, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Brokholi yaseTshayina ayikhuthazwa kwi-Pancreatic Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yi-Sunitinib kuba iguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYINGXAKI YOMFUNO INCEBISWA NGAPHEZU KWE-BROCCOLI YASECHINESE YEPancreatic Neuroendocrine Tumor KUNYE NONYANGO I-Sunitinib.

Khetha iSiqhamo RED RASPBERRY okanye STRAWBERRY GUAVA?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Epithelial ukuya kwi-Mesenchymal Transition, i-Angiogenesis kunye ne-Focal Adhesion kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Pancreatic Neuroendocrine Tumor xa unyango oluqhubekayo lomhlaza yi-Sunitinib. Oku kungenxa yokuba i-Red raspberry iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Sunitinib.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwiziqhamo ze-Strawberry Guava yi-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Strawberry Guava ayikhuthazwa kwi-Pancreatic Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yi-Sunitinib kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU ESIQINISEKISO SIYANXUSWA NGAPHEZU KWESTRAWBERRY GUAVA YEPancreatic Neuroendocrine Tumor KUNYE NONYANGO I-Sunitinib.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Formononetin, i-Lycopene, i-Phloretin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Growth Factor Signaling, i-Angiogenesis kunye ne-Focal Adhesion kunye nabanye. I-Butternut iyacetyiswa kwi-Pancreatic Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yi-Sunitinib. Oku kungenxa yokuba i-Butternut iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwenzululwazi ukuze zikhuthaze isiphumo se-Sunitinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Pancreatic Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yi-Sunitinib kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-EUROPA CHESTNUT YE-Pancreatic Neuroendocrine Tumor KUNYE NONYANGO I-Sunitinib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuza ye-Pancreatic Neuroendocrine Tumor okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable WILD LEEK okanye iRADISH?

I-Vegetable Wild Leek iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-Angiogenesis kunye ne-MYC Signaling kunye nezinye. I-Wild Leek icetyiswa kumngcipheko wePancreatic Neuroendocrine Tumor xa umngcipheko wemfuzo onxulumeneyo yi-DYNC1I1. Oku kungenxa yokuba iWild Leek yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeRadish yi-Curcumin, i-Apigenin, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling, i-Oxidative Stress kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. IRadish ayikhuthazwa xa umngcipheko wePancreatic Neuroendocrine Tumor xa umngcipheko wemfuzo uhambelana neDYNC1I1 kuba yonyusa iindlela zokutyikitya kuyo.

IMIFUNO YASEMDLENI IYACEBISWA NGAPHEZU KWERADISHI NGE-DYNC1I1 GENETIC RISK YOMHLAZA.

Khetha iSiqhamo se-NANCE okanye UMdiliya OQHELEKILEYO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-Angiogenesis kunye ne-MYC Signaling kunye nezinye. UNance ucetyiswa kumngcipheko wePancreatic Neuroendocrine Tumor xa umngcipheko wemfuzo ohambelana neDYNC1I1. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo soMdiliya oqhelekileyo yi-Curcumin, i-Ellagic Acid, i-Quercetin, i-Linalool, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. Umdiliya oqhelekileyo awukhuthazwa xa umngcipheko wePancreatic Neuroendocrine Tumor xa umngcipheko wemfuzo uhambelana ne-DYNC1I1 kuba yonyusa iindlela zokutyikitya.

ISIQHAMO NANCE IYACEBISWA NGAPHEZU KOMdiliya OQHELEKILEYO KWI-DYNC1I1 GENETIC RISK YOMHLAZA.

Khetha i-Nutt EQHELEKILEYO I-HAZELNUT okanye i-CASHEW NUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko wePancreatic Neuroendocrine Tumor xa umngcipheko wemfuzo ohambelana neDYNC1I1. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Cashew Nut yi-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Growth Factor Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Cashew Nut ayikhuthazwa xa umngcipheko we-Pancreatic Neuroendocrine Tumor xa umngcipheko wemfuzo uhambelana ne-DYNC1I1 kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWE-CASHEW NUT NGE-DYNC1I1 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana nePancreatic Neuroendocrine Tumor. I-Pancreatic Neuroendocrine Izigulana zeTumor kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Pancreatic Neuroendocrine Tumor, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Pancreatic Neuroendocrine Tumor?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Uhlalutyo lwe-pan-cancer lwe-genomes epheleleyo.
• Iziphumo kunye nokubaluleka kwe-formononetin kumanqanaba okubonakaliswa kwe-HIF-1α kunye ne-VEGF kwizicubu zomhlaza womlomo wesibeleko.
• I-Geraniol inqanda i-tumorigenesis yesikhumba se-murine ngokumodareyitha intetho ye-COX-2, i-Ras-ERK1 / 2 indlela yokubonisa kunye ne-apoptosis.
• I-α-Terpineol inciphisa intlungu yomhlaza ngokumodareyitha uxinzelelo lwe-oxidative kunye nokuvinjelwa kwe-iNOS.
• Ulawulo olubi lwe-transducer yesignali kunye ne-activator ye-transcription-3 yokubonisa i-cascade yi-lupeol inqanda ukukhula kwaye yenza i-apoptosis kwiiseli ze-hepatocellular carcinoma.
• https://my.clevelandclinic.org/health/diseases/21970-pancreatic-neuroendocrine-tumors
• https://www.cancer.gov/types/pancreatic/patient/pnet-treatment-pdq