Ukutya kwePancreatobiliary Ampullary Carcinoma!

intshayelelo

Ukutya kwePancreatobiliary Ampullary Carcinoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

KwiPancreatobiliary Ampullary Carcinoma ingaba inomsebenzi ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje ngePancreatobiliary Ampullary Carcinoma ingaba ayinamsebenzi ukuba kukutya ntoni na endingakutyiyo okanye endingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngePancreatobiliary Ampullary Carcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno iWild Leek ityiwa kakhulu xa ithelekiswa nespinatshi? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyathandwa kunerharnati? Kwakhona ukuba ukhetho olufanayo lwenzelwe amandongomane/imbewu efana neButternut ngaphezulu kweChestnut yaseYurophu kunye nezityalo ezifana neHyacinth Bean phezu kweCatjang Pea. Kwaye ukuba into endiyityayo ibalulekile - ke umntu uchonga njani ukutya okucetyiswayo kwiPancreatobiliary Ampullary Carcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiPancreatobiliary Ampullary Carcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo iCurcumin, iLycopene, iQuercetin, iNaringenin, iProtocatechuic Acid. Kwaye iPomegranate iqulethe izithako ezisebenzayo i-Curcumin, i-Ellagic Acid, i-Quercetin, i-Daidzein, i-Lupeol kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwiPancreatobiliary Ampullary Carcinoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo ukwenza isigqibo sesondlo sePancreatobiliary Ampullary Carcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiPancreatobiliary Ampullary Carcinoma?

Isondlo esilungiselelwe wena somhlaza njengePancreatobiliary Ampullary Carcinoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Pancreatobiliary Ampullary Carcinoma biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okuhambelana nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana nePancreatobiliary Ampullary Carcinoma

Zonke ii-cancer ezifana ne-Pancreatobiliary Ampullary Carcinoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya zePancreatobiliary Ampullary Carcinoma. Iindlela ze-Biochemical ezifana ne-RAS-RAF Ukubonakaliswa, ukulungiswa kwe-DNA, i-PI3K-AKT-MTOR Ukubonakaliswa, ii-Cell Cycle Checkpoints ziyingxenye yenkcazo yesignesha ye-Pancreatobiliary Ampullary Carcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Pancreatobiliary Ampullary Carcinoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwiPancreatobiliary Ampullary Carcinoma xa uthatha unyango lomhlaza IRadiation, kunye nokunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-KRAS, i-SMAD4, i-MED12 kunye ne-CTNNB1 zezona ziphezulu iigenes ezixeliweyo ze-Pancreatobiliary Ampullary Carcinoma. I-TP53 ixelwe kwi-71.4% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-KRAS ibikwa kwi-42.9%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-62.5% yedatha yesigulane ichongwa njengamadoda. I-Pancreatobiliary Ampullary Carcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo zePancreatobiliary Ampullary Carcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable WILD LEEK okanye ISIPINACH?

I-Vegetable Wild Leek iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Protocatechuic Acid, i-Daidzein, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Epithelial kwi-Mesenchymal Transition, i-MAPK Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Wild Leek icetyiswa ngePancreatobiliary Ampullary Carcinoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba i-Wild Leek ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo soMbane.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno Isipinashi yi-Curcumin, i-Quercetin, i-Protocatechuic Acid, i-Alpha Lipoic Acid, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-MAPK yokuSayina kunye nabanye. Isipinatshi asikhuthazwa kwi-Pancreatobiliary Ampullary Carcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-LEEK YASEMTHETHO YEMIFUNO IYAKUCEBISWA PHEZU KWESIPINACH SEPancreatobiliary Ampullary Carcinoma KUNYE NONYANGO LWERadiation.

Khetha iSiqhamo sePOMEGRANATE okanye iPUMMELO?

Iziqhamo zePomegranate ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Daidzein, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial ukuya kwi-Mesenchymal Transition, i-TGFB Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. Irharnathi iyacetyiswa kwiPancreatobiliary Ampullary Carcinoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba irharnathi ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo yiCurcumin, iLycopene, iQuercetin, iNaringenin, iProtocatechuic Acid. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-TGFB Signaling kunye nabanye. IPummelo ayikhuthazwa kwiPancreatobiliary Ampullary Carcinoma xa unyango lomhlaza oluqhubekayo iRadiation kuba ilungisa ezo ndlela zebiochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO IGORGRANATE IYAKUNIKEZWA NGAPHEZU KWE-PUMMELO YE-Pancreatobiliary Ampullary Carcinoma KUNYE NONYANGO LWERadiation.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lycopene, i-Protocatechuic Acid, i-Caffeine, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial ukuya kwi-Mesenchymal Transition, i-RAS-RAF yokuSayina kunye ne-MYC yokuSayina kunye nabanye. I-Butternut iyacetyiswa kwi-Pancreatobiliary Ampullary Carcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation. Oku kungenxa yokuba i-Butternut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Curcumin, i-Ellagic Acid, i-Quercetin, i-Protocatechuic Acid, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-TGFB Signaling kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa kwiPancreatobiliary Ampullary Carcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-EUROPA CHESTNUT YE-Pancreatobiliary Ampullary Carcinoma KUNYE NONYANGO lweRadiation.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuzo ye-Pancreatobiliary Ampullary Carcinoma okanye imbali yosapho uthi "Yintoni endifanele nditye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR okanye IKHABHAGEJI EMHLOPHE?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Myricetin, i-Apigenin, i-Lupeol, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition, i-TGFB yokuSayina kunye ne-Stem Cell Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko wePancreatobiliary Ampullary Carcinoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeKhaphetshu emhlophe yi-Curcumin, i-Quercetin, i-Lupeol, i-Isoliquiritigenin, i-Benzyl Isothiocyanate. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. Ikhaphetshu emhlophe ayikhuthazwa xa umngcipheko wePancreatobiliary Ampullary Carcinoma xa umngcipheko wemfuzo unxulunyaniswa neCTNNB1 kuba yonyusa iindlela zayo zokutyikitya.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA NGAPHEZU KWEKHABHUJI EMHLOPHE NGE-CTNNB1 GENETIC RISK YOMHLAZA.

Khetha iFruit NANCE okanye iJUJUBE?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Myricetin, i-Apigenin, i-Lupeol, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition, i-TGFB yokuSayina kunye ne-Stem Cell Signaling kunye nabanye. UNance ucetyiswa kumngcipheko wePancreatobiliary Ampullary Carcinoma xa umngcipheko wemfuzo onxulumeneyo yiCTNNB1. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeJujube yi-Curcumin, i-Quercetin, i-Myricetin, i-Apigenin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, Epithelial to Mesenchymal Transition kunye ne-Oxidative Stress kunye nabanye. IJujube ayikhuthazwa xa umngcipheko wePancreatobiliary Ampullary Carcinoma xa umngcipheko wezofuzo uhambelana ne-CTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWEJUJUBE NGE-CTNNB1 GENETIC RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lupeol, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-Angiogenesis kunye ne-MAPK yokuSayina kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko wePancreatobiliary Ampullary Carcinoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Curcumin, i-Ellagic Acid, i-Myricetin, i-Apigenin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-WNT Beta Catenin Signaling kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Pancreatobiliary Ampullary Carcinoma xa umngcipheko wemfuzo uhambelana ne-CTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWE-CHESTNUT NGE-CTNNB1 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana nePancreatobiliary Ampullary Carcinoma. Izigulana zePancreatobiliary Ampullary Carcinoma kunye nabantu abasengozini yemfuzo bahlala benombuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezinje ngePancreatobiliary Ampullary Carcinoma, nganye ineemfuza ezahlukeneyo zethumba ezinolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neWild Leek kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Pancreatobiliary Ampullary Carcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• I-Protocatechuic acid inqanda iiseli zomhlaza wemiphunga ngokumodareyitha i-FAK, i-MAPK, kunye neendlela ze-NF-κB.
• I-Betulinic Acid iNxinzelela iMetastasis yoMhlaza wamabele ngokuJonga i-GRP78-Mediated Glycolysis kunye ne-ER Stress Apoptotic Pathway.
• I-asidi ye-Gallic ixhokonxa umonakalo we-DNA kwaye icinezela i-DNA yokulungisa i-gene expression kwi-prostate cancer yomntu iiseli ze-PC-3.
• I-Retinol inciphisa amanqanaba eprotheyini ye-beta-catenin kwimigca yeseli ye-retinoic acid-resistant colon cancer.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.
• I-Lycopene ngokwahlukileyo idala i-quiescence kunye ne-apoptosis kwi-androgen-esabelayo kunye ne-independent ye-prostate cancer celllines.
• I-Chemoprevention of intestinal tumorigenesis yindalo yokutya i-flavonoid myricetin kwi-APCMin/+ iimpuku.