Ukutya kwe-Ocular Melanoma!

intshayelelo

Ukutya kwe-Ocular Melanoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Ocular melanoma, uhlobo olunqabileyo kodwa olunzima lomhlaza wamehlo, lunika imiceli mngeni eyahlukileyo ekuxilongeni nasekunyangeni. Iifoto ze-ocular melanoma zibonisa ukubonakala kwayo ngokomzimba, inceda ekubhaqweni kwangoko. Uluhlu lwe-ICD-10 lubonelela ngekhowudi esemgangathweni yokuxilongwa kunye neenjongo ze-inshurensi. Kwiradiology, ubuchule bokucinga bubalulekile ekuchongeni nasekuvavanyeni ubungakanani bethumba. Izinga lokusinda kunye ne-prognosis ye-ocular melanoma inokwahluka, iphenjelelwa zizinto ezinjengeentlobo ze-ocular melanoma kunye nenqanaba lokuxilongwa. Iinketho zonyango zisusela kunyango lwemitha, oluqhele ukusetyenziswa, ukuya kunyango olusakhulayo oluphononongwayo kulingo lwezonyango. Inkcazo kunye nenkcazo ye-pathology ye-ocular melanoma ibalulekile ekuqondeni ubunjani bayo kunye nophuhliso. Uphando luyaqhubeka nokuphonononga imiba efana ne-ocular melanoma genetics kunye nobume besifo esinokubakho. I-Immunotherapy kunye neendlela ezintsha zonyango ze-ocular melanoma zizifundo eziqhubekayo, ezinika ithemba lolawulo olusebenzayo. Ukubaluleka kokuxilongwa kwangaphambili akukwazi ukugqithiswa, njengoko i-melanoma ye-ocular enobungozi inokukhokelela kwiingxaki ezinkulu. Izigulane kunye nababoneleli bezempilo bahlala bebhenela kwizibonelelo ezifana ne-PowerPoint presentations (PPT) ukuze bazifundise ngale meko, begxininisa imfuneko yokufunda okuqhubekayo kunye nokuqhubela phambili kunyango lwe-ocular melanoma.

Kwi-Ocular Melanoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana ne-Ocular Melanoma ingaba ibalulekile into yokutya endikutyayo kwaye ndingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje nge-Ocular Melanoma?

Umzekelo ingaba inomsebenzi ukuba imifuno ye-Giant Butterbur ityiwa kakhulu xa ithelekiswa neChicory? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyathandwa kuneRed Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neHazelnut eqhelekileyo ngaphezu kweChestnut yaseYurophu kunye nezityalo ezifana nePea enamehlo aMnyama phezu kweYardlong Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu ukuchonga njani ukutya okucetyiswayo kwi-Ocular Melanoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Ocular Melanoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo iQuercetin, Formononetin, Curcumin, Daidzein, Phloretin. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Quercetin, i-Ellagic Acid, i-Formononetin, i-Curcumin, i-Daidzein kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo nokukhetha ukutya oza kukutya kwi-Ocular Melanoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungahoyi ezinye. Kuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Ocular Melanoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Ocular Melanoma?

Isondlo somntu somhlaza onje nge-Ocular Melanoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubungcali kwi-Ocular Melanoma biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Ocular Melanoma

Yonke imihlaza efana ne-Ocular Melanoma inokuphawulwa ngeseti eyodwa yeendlela ze-biochemical - iindlela zokutyikitya ze-Ocular Melanoma. Iindlela ze-Biochemical ezifana ne-RAS-RAF Signaling, i-mRNA Splicing, i-G-protein-coupled Receptor Signaling, i-Platelet aggregation iyingxenye yenkcazo yesignesha ye-Ocular Melanoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Ocular Melanoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali enxulumene nesigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Ocular Melanoma xa uthatha unyango lomhlaza Imitha, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-GNAQ, i-GNA11, i-SF3B1, i-BAP1 kunye ne-EIF1AX zezona ziphezulu iigenes ezixeliweyo ze-Ocular Melanoma. I-GNAQ ixelwe kwi-30.3% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-GNA11 ixelwe kwi-27.3%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-52.0% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji ye-Ocular Melanoma kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeOcular Melanoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR or CHICORY?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Formononetin, i-Curcumin, i-Daidzein, i-Phloretin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayokhemikhali ezifana noMjikelo weSeli, i-Angiogenesis, ukusinda kweeseli kunye nokuSayina kwe-MYC kunye nezinye. I-Giant Butterbur iyacetyiswa kwi-Ocular Melanoma xa unyango lomhlaza oluqhubekayo luyiRadiation. Oku kungenxa yokuba i-Giant Butterbur ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zazise isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeChicory yiQuercetin, Formononetin, Curcumin, Daidzein, Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Focal Adhesion kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chicory ayikhuthazwa kwi-Ocular Melanoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba ilungisa ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYINGXAKI YEMIFUNO INCEBISWA NGAPHEZU KWECHICORY YEOcular Melanoma KUNYE NONYANGO LWERadiation.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Ellagic Acid, i-Formononetin, i-Curcumin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, uMjikelo weSeli, i-Angiogenesis kunye nokuSayina kwe-MAPK kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Ocular Melanoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba i-Red raspberry iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yiQuercetin, Formononetin, Curcumin, Daidzein, Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye noxinzelelo lwe-Oxidative kunye nezinye. IPummelo ayikhuthazwa kwi-Ocular Melanoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba ilungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU IRASPBHARI IYACEBISWA NGAPHEZU KWE-PUMMELO YE-Ocular Melanoma KUNYE NONYANGO LWERadiation.

Khetha i-Nutt EQHELEKILEYO IHAZELNUT okanye i-EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Formononetin, i-Curcumin, i-Daidzein, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-Angiogenesis kunye nokulungiswa kwe-DNA kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kwiOcular Melanoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba iHazelnut eqhelekileyo iguqula ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Ellagic Acid, i-Formononetin, i-Curcumin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Ocular Melanoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba ilungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IHAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-EUROPE-CHESTNUT YE-Ocular Melanoma KUNYE NONYANGO LWEmitha.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuza ye-Ocular Melanoma okanye imbali yosapho uthi "Yintoni endifanele nditye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable WILD LEEK okanye MOUNTAIN YAM?

Imifuno ye-Wild Leek iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Delphinidin, i-Vitamin C. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-Oncogenic Cancer Epigenetics kunye ne-MYC Signaling kunye nabanye. I-Wild Leek icetyiswa kumngcipheko we-Ocular Melanoma xa ingozi yemfuzo eyayanyaniswa nayo yi-BAP1. Oku kungenxa yokuba iWild Leek yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Mountain Yam yi-Lycopene, i-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-G-protein-coupled Receptor Signaling kunye nezinye. I-Mountain Yam ayikhuthazwa xa umngcipheko we-Ocular Melanoma xa umngcipheko wezofuzo uhambelana ne-BAP1 kuba yonyusa iindlela zokutyikitya kuyo.

I-LEEK YASEMTHETHO YOMFUNO ICEBISIWE PHEZU KWENTABA YAM NGE-BAP1 YOMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iSiqhamo SOURSOP okanye BAYBERRY?

I-Fruit Soursop iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Emodin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Phospholipase Signaling, i-G-protein-coupled Receptor Signaling kunye ne-MYC Signaling kunye nabanye. I-Soursop icetyiswa kumngcipheko we-Ocular Melanoma xa umngcipheko wemfuzo ohambelana ne-BAP1. Oku kungenxa yokuba i-Soursop yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo ze-Bayberry yi-Lycopene, i-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-G-protein-coupled Receptor Signaling kunye nezinye. I-Bayberry ayikhuthazwa xa umngcipheko we-Ocular Melanoma xa umngcipheko wezofuzo uhambelana ne-BAP1 kuba yonyusa iindlela zokutyikitya.

ISIQHAMO SOURSOP KUCEBISWA PHEZU KWE-BAYBERRY FOR BAP1 GENETIC RISK YOMHLAZA.

Khetha Nut HAZELNUT okanye HICKORY NUT?

I-Hazelnut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Delphinidin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling kunye ne-MYC Signaling kunye nezinye. IHazelnut icetyiswa kumngcipheko we-Ocular Melanoma xa umngcipheko wemfuzo ohambelana ne-BAP1. Oku kungenxa yokuba iHazelnut yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Hickory Nut yi-Lycopene, i-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-G-protein-coupled Receptor Signaling kunye nezinye. I-Hickory Nut ayikhuthazwa xa umngcipheko we-Ocular Melanoma xa umngcipheko wezofuzo uhambelana ne-BAP1 kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT IYAKUNCEBISWA PHEZU KWE-HICKORY NUT YE-BAP1 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Ocular Melanoma. Izigulana ze-Ocular Melanoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Ocular Melanoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo se-addon sesondlo somntu senza ukuba isigqibo sibe lula kwaye sisuse lonke uqikelelo ekuphenduleni umbuzo, "Kukuphi ukutya endimele ndikukhethe okanye ndingakukhethi kwi-Ocular Melanoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

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