Ukutya koMhlaza weMiphunga yeSeli engeNcinci!

intshayelelo

Ukutya kwiSeli yoMhlaza weMiphunga engeNcinci kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

KuMhlaza weMiphunga yeSeli engeNcinane ingaba ayinamsebenzi ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana noMhlaza weMiphunga yeSeli engeNcinci ingaba ibalulekile into yokuba kokuphi ukutya endikutyayo kwaye ndingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwizityalo ngaba oko kwanele kumhlaza ofana noMhlaza weLung weSeli engeNcinci?

Umzekelo ingaba inomsebenzi ukuba iCauliflower yemifuno ityiwa kakhulu xa ithelekiswa neRocket Salad (ssp.)? Ngaba kuyawenza umahluko ukuba isiqhamo iMalus (unonkala weApile) sikhethwa ngaphezu kweBlack Mulberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kumandongomane/imbewu efana neButternut ngaphezulu kweChestnut yaseYurophu kunye neepulses ezifana neGram Bean phezu kweMung Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kuMhlaza weMiphunga yeSeli encinci kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kuyingxaki kuMhlaza weMiphunga yeSeli encinci!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo i-Malus (i-crab Apple) iqulethe izithako ezisebenzayo i-Curcumin, i-Delphinidin, i-Lycopene, i-Isoliquiritigenin, i-Formononetin. Kwaye i-Black Mulberry iqulethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Delphinidin, i-Isoliquiritigenin, i-Formononetin kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwayo xa kusenziwa isigqibo nokukhetha ukutya okuza kutyiwa kuMhlaza Womhlaza weMiphunga yeSeli engeyincinci - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungazihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo soMhlaza ongeNcinci weCell Lung.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kuMhlaza weMiphunga yeSeli engeNcinci?

Isondlo esilungiselelwe wena somhlaza onjengoMhlaza weMiphunga yeSeli engeNcinane siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yoMhlaza wamaLung eSeli engeNcinci, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana noMhlaza weMiphunga yeSeli engeyincinci

Yonke imihlaza efana noMhlaza weMiphunga yeSeli engeNcinane inokuphawulwa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya zoMhlaza weMiphunga yeSeli engeNcinci. Iindlela ze-Biochemical ezifana ne-RAS-RAF Signaling, i-Apoptosis, i-Molekyuli encinci yezoThutho, i-Extracellular Matrix Remodeling iyingxenye yenkcazo yesiginesha ye-Cancer yeLung ye-Cell encinci. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kuMhlaza ongeNcinci weSeli yeMiphunga kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwiCancer yeLung yeSeli encinci xa uthatha unyango lomhlaza i-Erlotinib, kunye nokutya okunye kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-LRP2, i-CACNA1E, i-SI, i-TIAM1 kunye ne-COL6A3 zezona zakhi zofuzo zibekwe kwindawo ephezulu kuMhlaza ongeNcinci weSeli yemiphunga. I-LRP2 ixelwe kwi-10.1 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-CACNA1E ixelwe kwi-9.4%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-37 ukuya kuma-88. Ama-49.4% edatha yezigulane ichongwe njengamadoda. Ibhayoloji yoMhlaza weMiphunga yeSeli engeNcinci kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo zoMhlaza weMiphunga yeSeli engeNcinci

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CAULIFLOWER okanye ROCKET SALAD (SSP.)?

I-Cauliflower yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Delphinidin, i-Isoliquiritigenin, i-Formononetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition, i-P53 Signaling, i-WNT Beta Catenin Signaling kunye ne-MYC Signaling kunye nabanye. ICauliflower iyacetyiswa kuMhlaza weMiphunga yeSeli engeNcinci xa unyango lomhlaza oluqhubekayo yi-Erlotinib. Oku kungenxa yokuba iCauliflower iguqula ezo ndlela zebhayomichimi ekuye kwaxelwa ngokwenzululwazi ukuba zinike impembelelo ye-Erlotinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Rocket Salad (ssp.) I-Quercetin, i-Curcumin, i-Delphinidin, i-Lycopene, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. Isaladi ye-Rocket (ssp.) ayikhuthazwa kwi-Non-small Lung Cancer xa unyango lomhlaza oluqhubekayo yi-Erlotinib kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

I-CAULIFLOWER YOMFUNO INCEBISWA NGAPHEZU KWE-ROCKET SALAD (SSP.) NGENXA Engeyiyo encinci yeCell Lung Cancer KUNYE NONYANGO i-Erlotinib.

Khetha iSiqhamo seMULBERRY EMNYAMA okanye i-MALUS (I-APPLE YOMHLABA)?

Iziqhamo ze-Mulberry eziMnyama ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Delphinidin, i-Isoliquiritigenin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition, i-Extracellular Matrix Remodelling, i-Apoptosis kunye ne-MAPK yokuSayina kunye nabanye. Black Mulberry kucetyiswa Non-incinci Cell Lung Cancer xa unyango umhlaza oluqhubekayo Erlotinib. Oku kungenxa yokuba i-Black Mulberry ilungisa ezo ndlela ze-biochemical ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Erlotinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeMalus (i-crab Apple) yi-Curcumin, i-Delphinidin, i-Lycopene, i-Isoliquiritigenin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Malus (i-Apile yoononkala) ayikhuthazwa kwi-Non-incinci ye-Cell Lung Cancer xa unyango lomhlaza oluqhubekayo yi-Erlotinib kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO OMNYAMA EMNYAMA KUNCEBISWA NGAPHEZU KWE-MALUS (I-APPLE YOMHLABA) KUMhlaza ongengowomncinci weSeli weMiphuphu KUNYE NONYANGO i-Erlotinib.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Delphinidin, i-Lycopene, i-Isoliquiritigenin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, P53 Signaling, MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Butternut icetyiswa kwi-Non-small Lung Cancer xa unyango lomhlaza oluqhubekayo yi-Erlotinib. Oku kungenxa yokuba i-Butternut ilungisa ezo ndlela zebhayochemicals ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Erlotinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Ellagic Acid, i-Curcumin, i-Delphinidin, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, Epithelial to Mesenchymal Transition kunye ne-WNT Beta Catenin Signaling kunye nabanye. I-Chestnut yaseYurophu ayicetyiswa kuMhlaza weMiphunga yeSeli engeNcinci xa unyango lomhlaza oluqhubekayo yi-Erlotinib kuba lulungisa ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISIWE NGAPHEZU KWE-EUROPA CHESTNUT FOR Umhlaza wemiphunga yeSeli engeyincinci KUNYE NONYANGO Erlotinib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwayo ngabantu abasengozini yemfuza yoMhlaza ongeNcinci weCell Lung Cancer okanye imbali yosapho uthi "Yintoni endifanele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nesignesha yendlela - ukhetho lokutya kunye nezongezelelo kufuneka lube lomntu.

Khetha iVegetable GIANT BUTTERBUR or OYSTER MUSHROOM?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Adherens junction, i-P53 Signaling, i-Cell Junctions kunye ne-RAS-RAF Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko woMhlaza weMiphunga yeSeli engeyincinci xa ingozi yemfuzo eyayanyaniswa nayo yi-CACNA1E. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Oyster Mushroom yemifuno yi-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Molecule yoThutho encinci kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Oyster Mushroom ayikhuthazwa xa umngcipheko woMhlaza weMiphunga yeSeli engeNcinci xa umngcipheko wemfuzo unxulunyaniswa ne-CACNA1E kuba yonyusa iindlela zokutyikitya.

IBHUTTERBURE EYISINXIBA YOMFUNO IYAKUNCEBISWA NGAPHEZU KWE-OYSTER MUSHROOM NGE-CACNA1E genetic RISK YOMHLAZA.

Khetha iSiqhamo CLOUDBERRY okanye iPUMMELO?

Isiqhamo se-Cloudberry siqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Quercetin, i-Ellagic Acid, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Adherens junction, i-P53 Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Cloudberry iyacetyiswa kumngcipheko we-Non-small Cell Lung Cancer xa umngcipheko wemfuzo ohambelana ne-CACNA1E. Oku kungenxa yokuba i-Cloudberry yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi batyikityo lwayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Extracellular Matrix Remodelling, i-Moleculi encinci yoThutho, i-Cytoskeletal Dynamics kunye ne-Cell Junctions kunye nabanye. IPummelo ayikhuthazwa xa umngcipheko woMhlaza weMiphunga yeSeli engeNcinci xa umngcipheko wemfuzo unxulunyaniswa ne-CACNA1E kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO ICLOUDBERRY IYACEBISWA NGAPHEZU KWE-PUMMELO NGE-CACNA1E genetic RISK YOMHLAZA.

Khetha Nut CHIA okanye PISTACHIO?

I-Chia iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-P53 Signaling, i-Focal Adhesion, iiJunctions zeCell kunye ne-Molecule yoThutho encinci kunye nabanye. I-Chia icetyiswa kumngcipheko woMhlaza weMiphunga yeSeli engeNcinci xa umngcipheko wemfuzo onxulumeneyo yi-CACNA1E. Oku kungenxa yokuba i-Chia yonyusa ezo ndlela zebhayoloji ezichasana nabaqhubi abatyikityayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Pistachio yi-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Focal Adhesion, i-Cytoskeletal Dynamics kunye ne-Cell Junctions kunye nabanye. I-Pistachio ayikhuthazwa xa umngcipheko woMhlaza weMiphunga yeSeli engeyincinci xa umngcipheko wemfuzo ohambelana ne-CACNA1E kuba yonyusa iindlela zokutyikitya kuyo.

I-CHIA ICEBISIWE PHEZU KWE-PISTACHIO YE-CACNA1E genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana noMhlaza weMiphunga yeSeli engeNcinci. Izigulana zoMhlaza weMiphuphu engeyiyo encinci kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana noMhlaza weMiphunga yeSeli engeNcinci, nganye inemfuza eyahlukileyo yethumba enolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neCauliflower kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo se-addon yesondlo somntu senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kuMhlaza ongeNcinci weCell Lung?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• I-Pan Origised 2020
• I-Molecular Deteminants of Respents to Anti-Programmed Cell Death (PD)-1 kunye ne-Anti-Programmed Death-Ligand 1 (PD-L1) iBhlokhi kwizigulane ezinoMhlaza ongeNcinci weMiphunga eNcinciweyo echazwe ngokulandelelana kwesizukulwana esilandelayo.
• I-Morsin ibangela ukufa kweeseli ngokungasebenzisi umqondiso we-STAT3 kwiiseli zomhlaza wedlala lobudoda.
• I-Vitamin C iphucula ukuguqulwa kwe-epigenetic eyenziwa yi-5-azacytidine kunye nokubanjwa komjikelo weseli kwi-hepatocellular carcinoma celllines HLE kunye ne-Huh7.
• I-Brassinin icinezela amandla okuHlabaza okuHlangeneyo kweeSeli ze-Lung Carcinoma ngoKucinywa kwe-PI3K/Akt/mTOR I-Signaling Cascade.
• I-β-Sitosterol kunye neGemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity ngokuModulating i-Apoptosis kunye ne-Inhibiting Epithelial-Mesenchymal Transition ngo-Deactivating Akt / GSK-3β Signaling.
• Impembelelo ye-Antiproliferative ye-p-Coumaric acid ijolise ekusebenzeni kwe-UPR ngokunciphisa i-Grp78 kumhlaza wekoloni.