Ukutya kwe-Oligoastrocytoma!

intshayelelo

Ukutya kwe-Oligoastrocytoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Oligoastrocytoma, i-tumor yengqondo equlethe zombini i-astrocytic kunye ne-oligodendroglial components, ihlelwa ngamabakala, kunye nebakala le-2 lingaphantsi kobudlova xa lithelekiswa ne-3 kunye ne-4. I-pathology outlines kunye ne-histology ye-oligoastrocytoma zingundoqo ekunqumeni ibakala kunye nesicwangciso sonyango esilandelayo. I-radiological imaging idlala indima ebalulekileyo ekuxilongweni, ehlelwa phantsi kwenkqubo ye-ICD-10 yekhowudi. Izinga lokusinda kunye ne-prognosis ye-oligoastrocytoma iyahluka ngokuxhomekeka kwibakala layo; I-oligoastrocytoma yebakala lesi-3 inezinga elisezantsi lokusinda xa lithelekiswa nebanga lesi-2, kwaye ubude bokuphila buyancipha ngakumbi ngebakala lesi-4. Unyango lubandakanya indibaniselwano yotyando, ngemitha, kunye nechemotherapy, elungelelaniswe neempawu zethumba. I-Oligoastrocytoma inokuba ngumhlaza, kunye nendalo yayo ukusuka kwi-benign kumabanga asezantsi ukuya kwi-malignant kumabanga aphezulu. Ukuqonda umahluko phakathi kwe-oligoastrocytoma kunye namathumba afana ne-glioblastoma kunye ne-oligodendroglioma kubalulekile kuxilongo oluchanekileyo kunye nolawulo olusebenzayo.

Kwi-Oligoastrocytoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana ne-Oligoastrocytoma ingaba ibalulekile na into yokutya endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje nge-Oligoastrocytoma?

Umzekelo ingaba iyabaluleka na into yokuba umnqathe wemifuno utyiwa kakhulu xa uthelekiswa nekhaphetshu emhlophe? Ngaba kuyawenza umahluko ukuba isiqhamo uAbiyuch siyakhethwa kuneBlackberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut ngaphezu kweChestnut yaseYurophu kunye nezityalo ezifana neCowpea ngaphezu kweCommon Bean. Kwaye ukuba into endiyityayo ibalulekile - ke umntu uchonga njani ukutya okucetyiswayo kwi-Oligoastrocytoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kubalulekile kwi-Oligoastrocytoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo i-Abiyuch iqulethe izithako ezisebenzayo iCatechol, i-Curcumin, i-Apigenin, i-Daidzein, i-Caffeine. Kwaye iBlackberry iqulethe izithako ezisebenzayo iCinnamaldehyde, Ellagic Acid, Linalool, Myricetin, Quercetin kunye nezinye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Oligoastrocytoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungayihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Oligoastrocytoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Oligoastrocytoma?

Isondlo esilungiselelwe wena somhlaza njenge-Oligoastrocytoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchule kwibhayoloji ye-Oligoastrocytoma, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Oligoastrocytoma

Yonke imihlaza efana ne-Oligoastrocytoma inokubonakaliswa ngeseti eyodwa yeendlela ze-biochemical - iindlela zokutyikitya ze-Oligoastrocytoma. Iindlela ze-Biochemical ezifana ne-Hypoxia, i-Notch Signaling, i-Oncogenic Cancer Epigenetics, i-Energy Metabolism iyingxenye yenkcazo yesignesha ye-Oligoastrocytoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Oligoastrocytoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulane ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwi-Oligoastrocytoma xa uthatha unyango lomhlaza weProcarbazine, kunye nokutya okunye kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-IDH1, i-ATRX, i-ABL1, i-ARID2 kunye ne-ASXL1 zezona ntlobo zemfuza ezixeliweyo eziphezulu ze-Oligoastrocytoma. I-IDH1 ixelwe kwi-100.0% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-ATRX ixelwe kwi-50.0%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-50.0% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji ye-Oligoastrocytoma kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo ze-Oligoastrocytoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CARROT okanye IKHABHAGEJI EMHLOPHE?

I-Carrot yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana neCatechol, i-Curcumin, i-Apigenin, i-Isorhamnetin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Notch Signaling, i-Hypoxia kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. Umnqathe uyacetyiswa kwi-Oligoastrocytoma xa unyango lomhlaza oluqhubekayo yiProcarbazine. Oku kungenxa yokuba i-Carrot iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze umphumo weProcarbazine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno emhlophe yeKhaphetshu yiCatechol, Curcumin, Daidzein, Cinnamaldehyde, Benzyl Isothiocyanate. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. Ikhaphetshu emhlophe ayikhuthazwa ukuba i-Oligoastrocytoma xa unyango lomhlaza oluqhubekayo yi-Procarbazine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

I-CARROT YOMFUNO INCEBISWA PHEZU KWEKHABHAGEJI EMHLOPHE YE-Oligoastrocytoma KUNYE NONYANGO I-Procarbazine.

Khetha iFruit BLACKBERRY okanye i-ABIYUCH?

I-Fruit Blackberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana neCinnamaldehyde, i-Ellagic Acid, i-Linalool, i-Myricetin, i-Quercetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Hypoxia kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Blackberry iyacetyiswa kwi-Oligoastrocytoma xa unyango lomhlaza oluqhubekayo yiProcarbazine. Oku kungenxa yokuba i-Blackberry iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze umphumo weProcarbazine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo uAbiyuch yiCatechol, Curcumin, Apigenin, Daidzein, Caffeine. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Abiyuch ayikhuthazwa kwi-Oligoastrocytoma xa unyango lomhlaza oluqhubekayo yi-Procarbazine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO EMNYAMA KUNCEBISWA NGAPHEZU KWE-ABIYUCH YE-Oligoastrocytoma KUNYE NONYANGO I-Procarbazine.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana neCatechol, i-Apigenin, i-Curcumin, i-Daidzein, i-Cinnamaldehyde. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Hypoxia kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Butternut iyacetyiswa kwi-Oligoastrocytoma xa unyango lomhlaza oluqhubekayo yi-Procarbazine. Oku kungenxa yokuba i-Butternut iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze umphumo weProcarbazine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yiCatechol, i-Curcumin, i-Apigenin, i-Daidzein, i-Cinnamaldehyde. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Oligoastrocytoma xa unyango lomhlaza oluqhubekayo yi-Procarbazine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-EUROPA CHESTNUT YE-Oligoastrocytoma KUNYE NONYANGO I-Procarbazine.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza ye-Oligoastrocytoma okanye imbali yosapho "Yintoni endimele ndiyitye ngokwahlukileyo ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable CELERY STLKS okanye CHICORY?

Imifuno ye-Celery Stalks iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Hypoxia, i-P53 Signaling kunye ne-Glutathione Metabolism kunye nabanye. Izikhondo zeCelery zicetyiswa kumngcipheko we-Oligoastrocytoma xa umngcipheko wemfuzo ohambelana ne-ABL1. Oku kungenxa yokuba i-Celery Stalks yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi abasayiniweyo bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Chicory yi-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Glutathione Metabolism kunye nabanye. I-Chicory ayikhuthazwa xa umngcipheko we-Oligoastrocytoma xa umngcipheko wezofuzo uhambelana ne-ABL1 kuba yongeza iindlela zokutyikitya kuyo.

IZIDLA ZEMIFUNO YECEREY IYAKUNQITSHISWA PHEZU KWECHICORY YE-ABL1 genetic RISK YOMHLAZA.

Khetha iSiqhamo se-BAEL okanye iGRAPEFRUIT?

I-Fruit Bael iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Beta-sitosterol, i-Vitamin C, i-Linolenic Acid, i-Oleic Acid, i-Auraptene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-Hypoxia, i-P53 Signaling kunye ne-MYC Signaling kunye nabanye. I-Bael icetyiswa kumngcipheko we-Oligoastrocytoma xa umngcipheko wemfuzo onxulumeneyo yi-ABL1. Oku kungenxa yokuba iBael yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGrapefruit yiCurcumin, iLupeol, iDaidzein, iBeta-sitosterol, iLycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Glutathione Metabolism kunye nabanye. I-Grapefruit ayikhuthazwa xa umngcipheko we-Oligoastrocytoma xa umngcipheko wezofuzo uhambelana ne-ABL1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO IBHAEL IYANCEBISWA NGAPHEZU KWEGRAPEFRUIT NGE-ABL1 genetic RISK YOMHLAZA.

Khetha Nut COLORADO PINYON okanye JAPANESE CHESTNUT?

I-Colorado Pinyon iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Apoptosis, i-P53 yokuSayina kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Colorado Pinyon iyacetyiswa kumngcipheko we-Oligoastrocytoma xa umngcipheko wemfuzo ohambelana ne-ABL1. Oku kungenxa yokuba iColorado Pinyon yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseJapan yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Glutathione Metabolism kunye nabanye. I-Chestnut yaseJapan ayikhuthazwa xa umngcipheko we-Oligoastrocytoma xa umngcipheko wezofuzo unxulunyaniswa ne-ABL1 kuba yonyusa iindlela zokutyikitywa kwayo.

I-COLORADO PINYON INCEBISWA NGAPHEZU KWE-CHESTNUT YASEJAPANE NGE-ABL1 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Oligoastrocytoma. Izigulana ze-Oligoastrocytoma kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Oligoastrocytoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okunjengoMnqathe kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Oligoastrocytoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
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• I-asidi ye-Shikimic ikhuthaza i-estrogen receptor (ER) -iiseli zomhlaza webele ezintle zikhula ngokusebenza kwe-NF-κB yokubonisa.
• Uhlalutyo lwe-molecular docking ye-Cianidanol esuka kwi-Ginkgo biloba kunye ne-HER2 + ekujoliswe kuyo kumhlaza webele.
• I-Eugenol ithintela iCancer Stem Cell ngokuthotywa kwe-β-catenin nge-N-terminal Ser37 phosphorylation-an in vivo kunye novavanyo lokulinga lwe-in vitro.
• I-Paederia foetida yenza umsebenzi we-anticancer ngokumodareyitha i-chromatin modification enzymes kunye nokuguqula i-pro-inflammatory cytokine gene expression kwiiseli zomhlaza we-prostate.
• I-lipidomics esebenzayo: I-Palmitic acid iphazamisa uphuhliso lwe-hepatocellular carcinoma ngokumodareyitha ulwelo lwe-membrane kunye ne-glucose metabolism.
• I-Luteolin ikhuthaza ukufa kweeseli ze-apoptotic ngokunyuswa kwe-Nrf2 inkcazo nge-DNA demethylase kunye nokusebenzisana kwe-Nrf2 kunye ne-p53 kwiiseli zomhlaza wekholoni yomntu.