Iimbalasane
Uphononongo lwakutsha nje olupapashwe kwijenali yesayensi lubonakalisile ukuba iiseli ezinomhlaza omnyama xa zinyangwa unyango lomhlaza ekujoliswe kulo NjengoCetuximab okanye iDabrafenib ikhulisa ukunganyangeki ngokutshintsha ii-genes ezithile kunye neendlela ezenza ukuba iiseli zomhlaza zitshintshe ngakumbi kwaye zibe ndlongondlongo kwaye zinganyangeki.
Rhoqo ngonyaka, izigidi zabantu kwihlabathi liphela ziyakhuthazwa kwaye ngamanye amaxesha kufuneka zithathe ugonyo lwemihla ngemihla oluchasene nokuqhambuka kwezifo. Nangona kunjalo, ukudutyulwa nje kube kanye akunakuwuphelisa ngokupheleleyo umngcipheko webhaktiriya okanye intsholongwane ethile kuba iintsholongwane ziyakwazi ukuvela kwaye zomelele ngakumbi, yiyo loo nto izazinzulu kunye noochwephesha bezonyango kufuneka bahlale bebeka esweni kwaye beyila izitofu ezintsha nezihlaziyiweyo. Ngokufanayo, kukho uluvo lokuba unyango lomhlaza olujoliswe kuyo, uhlobo lwechemotherapy apho amayeza ahlasela ngokuthe ngqo imfuza ethile okanye indawo engqonge ithumba, ingcono kunonyango oluqhelekileyo lwechemotherapy kuba luthe ngqo kuhlaselo lwayo. I-Chemotherapy kulo mxholo ibandakanya zombini amachiza ekhemikhali kunye ne-biological antibody. Cancer iiseli, ezifana neebhaktheriya kunye neentsholongwane, zikwanakho ukuqhubeka nokuguqula nokuguqula iinkqubo zazo zangaphakathi ukuze zithintele uhlaselo kwaye zinganyangeki kwiikhemotherapies ekujoliswe kuzo.
Ukutya okuTyiwa emva kokuChongwa koMhlaza!
Akukho mhlaza mibini ifanayo. Yiya ngaphaya kwezikhokelo zesondlo esiqhelekileyo kuwo wonke umntu kwaye wenze izigqibo ezizezakho malunga nokutya kunye nezongezo ngokuzithemba.
Iithagethi Zokuchasana Nonyango
Ngokusisiseko, xa naluphi na uhlobo lwechemotherapy, kubandakanywa unyango lwechemotherapy ekujoliswe kulo luqaliswa kwisigulana, lusebenza ekuqaleni kwaye lutshayela uninzi lweeseli zomhlaza, ngaphandle kwezimbalwa ezixhathisayo ngenxa yotshintsho oluqhubekayo. Umbuzo ngowokuba ingaba ezi seli zixhathisayo ziyakwazi na ukuguquka ngesantya esikhawulezayo kunesantya sokubulawa kweeseli zomhlaza ezisabelayo, ngaloo ndlela zanda ngepesenti kwaye zenza ithumba libe ndlongondlongo kwaye lixhathise kunyango ekujoliswe kulo. Kwaye ukuvavanya oku, abaphandi bezonyango abavela e-Italiya ngokubambisana ne-Harvard School of Public Health, benza uphando olubandakanya i-colorectal. umhlaza iiseli ziphathwe ngonyango olujoliswe kuyo i-Cetuximab, ichiza le-antibody elijoliswe ngokukodwa kwi-EGFR (i-epidermal growth factor) receptors, kunye ne-Dabrafenib, ichiza elincinci le-molecule elijoliswe kwi-oncogene ye-BRAF. Kolu pho nonongo, bafumanise ukuba ngokuthotywa kofuzo olubandakanyekayo ekulungiseni umonakalo we-DNA kunye nokuguqulwa kofuzo kunye nokulawulwa kwezakhi zofuzo eziza kukopisha i-DNA nangona zonakaliswe, "iiseli ze-tumor zibaleka uxinzelelo lwezonyango ngokunyusa ukuguqulwa"URusso M okqhubekayo, iSayensi. 2019).
Iimpembelelo zolu phononongo zibaluleke kakhulu ngokwendlela umntu azijonga ngayo iziphumo zonyango lwamva nje lomhlaza. Isizathu sokuba kutheni unyango lwe-chemo ekujoliswe kulo luye lwafumana ukuthandwa kukuba amanye amachiza sele ehambele phambili kakhulu kangangokuba ayakwazi ukuba neziphumo ezinetyhefu kuphela kwiiseli zomhlaza ezitshintshiweyo kwaye angonakalisi iiseli eziqhelekileyo zesigulana, ngaloo ndlela ehlisa iziphumo ebezingalindelekanga ezibi. yechemotherapy yesiqhelo. Ngokubhekiselele kwinto eyayinokwenzeka kwiminyaka engama-20-30 eyadlulayo, unyango olufana nolu lutshintsho. Nangona kunjalo, ngaphandle kwendlela yonyango eyenzelwe wena kunye nejolise kuyo eye yanceda ukujongana nomhlaza onganyangekiyo kakhulu, uphuhliso lonyango oluqhubekayo noluqhubekayo lube ngumqobo omkhulu kunyango ekujoliswe kulo. Yintoni efunekayo yindlela yobuntu yokuba endaweni yokusebenzisa unyango olujoliswe kuyo ngabanye, ngokucwangcisiweyo idibanisa unyango olusekelwe kwiimpawu ezizodwa ze-genomic kunye ne-molecular yesigulane ngasinye. umhlaza njengohlaselo olunamacala amaninzi olulungisa zonke iindlela zokuxhathisa ezinokuthi zisetyenziswe yiseli yomhlaza ukubaleka ukutshatyalaliswa.
Kukuphi ukutya okutyayo kwaye okuncedisayo kukuthatha sisigqibo osithathayo. Isigqibo sakho kufuneka sibandakanye ukuthathelwa ingqalelo kotshintsho lomhlaza kuhlobo lomhlaza, unyango oluqhubekayo kunye nezongezelelo, nakuphi na ukwaliwa, ulwazi ngobomi bakho, ubunzima, ukuphakama kunye nemikhwa.
Isicwangciso sesondlo somhlaza esivela kwi-addon asisekelwanga kukhangelo lwe-Intanethi. Isebenza ngokuzenzekelayo ukwenza izigqibo zakho kusekwe kwisayensi yemolekyuli ephunyezwe ngoososayensi kunye neenjineli zesoftware. Nokuba ukhathalele na ukuqonda iindlela ezisisiseko seemolekyuli okanye hayi - zokucwangciswa kwesondlo somhlaza ukuqonda kuyafuneka.
Qalisa NGOKU ngokucwangciswa kwesondlo ngokuphendula imibuzo ngegama lomhlaza, uguquko kwimfuza, unyango oluqhubekayo kunye nezincedisi, nakuphi na ukwaliwa, imikhwa, indlela yokuphila, iqela lobudala kunye nesini.
ISondlo esiSiqu soMhlaza!
Umhlaza uyatshintsha ngokuhamba kwexesha. Yenza ngokwezifiso kwaye uguqule isondlo sakho ngokusekwe kwisalathiso somhlaza, unyango, indlela yokuphila, ukhetho lokutya, i-allergies kunye nezinye izinto.
Izigulana ezinomhlaza zihlala zisebenza ngeendlela ezahlukeneyo iziphumo ebezingalindelekanga ezichaphazela umgangatho wobomi babo kwaye bajonge ezinye iindlela zonyango lomhlaza. Ukuthatha isondlo esifanelekileyo kunye nezongezelelo ezisekwe kuqwalaselo lwenzululwazi (ukunqanda ukuqikelela kunye nokukhetha okungahleliwe) sesona sixhobo sendalo somhlaza kunye neziphumo ebezingalindelekanga zonyango.