Zotsatira Zotsutsa Khansa za "Apigenin"

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Apigenin, chowonjezera chachilengedwe chochokera ku zomera chomwe chimapezeka m'masamba odziwika bwino, zipatso, zitsamba ndi zakumwa amadziwika kuti ali ndi ubwino wosiyanasiyana wa thanzi chifukwa cha zotsatira zake zotsutsana ndi khansa ndi zotupa. Kafukufuku wambiri wa labotale awonetsa momwe Apigenin ingathandizire kuletsa ma cell a khansa komanso momwe angagwirizanitse ndi chemotherapy mu mitundu ya khansa monga prostate, pancreatic, gastric ndi khansa zina..

Mliri wa matenda a khansa ndizochitika zosintha moyo zomwe zimatsogolera munthu kuti abwererenso ndikusintha moyo wawo komanso zomwe amasankha. Ngakhale kuti chemotherapy akadali njira imodzi yabwino kwambiri yochizira khansa, odwala amakhala osamala ndi zinthu zingapo zokhudzana ndi chemo makamaka zotsatira zake zoyipa komanso momwe moyo wawo uliri. Wodwala khansa amayang'ana njira zina zilizonse ndi chemotherapy, kuti apititse patsogolo 'zovuta' zawo. Njira imodzi yotere ndikuwonjezera zowonjezera zachilengedwe ndi zitsamba zomwe zakhala zikugwiritsidwa ntchito muzamankhwala azikhalidwe padziko lonse lapansi, kuti chitetezo chawo chiwonjezeke ndikuchiritsa katundu (mankhwala achilengedwe a khansa). Modus operandi kwa ambiri khansa Odwala ndi kusankha mwachisawawa kwa zomera izi zomwe zimachokera kuzinthu zachilengedwe zomwe zimakhala ndi zotsatira zotsutsana ndi khansa zomwe amayamba kuzitenga, ndi lingaliro lakuti zidzawathandiza kuthana ndi zotsatira zake popanda kuwonjezera katundu wa poizoni ndikuwonjezera mwayi wawo wopanda khansa. kupulumuka. Chimodzi mwazinthu zachilengedwe zotere ndi flavonoid yotchedwa Apigenin.

Apigenin ndi Magwero Ake Chakudya

Apigenin ndi flavonoid yazakudya (flavone) yomwe imapezeka muzomera zambiri, zipatso, ndiwo zamasamba ndi zakumwa kuphatikiza:

• Chamomile tiyi
• Parsley
• Selari
• sipinachi
• Date
• makangaza
• spearmint
• Basil
• oregano
• Fenugreek
• Adyo
• Vinyo wofiyira

Apigenin amagwira ntchito yofunika kwambiri pakuchiritsa kwa zitsamba zaku China.

Zolinga Zogwiritsidwa Ntchito / Ubwino Wathanzi wa Apigenin

Monga zinthu zambiri zachilengedwe zomwe zimagwiritsidwa ntchito mwamwambo, zimadziwika kuti Apigenin ali ndi anti-yotupa, antioxidant, antibacterial ndi antiviral zochita ndipo chifukwa chake amawonedwa kuti ali ndi maubwino ambiri azaumoyo. Zina mwazabwino zomwe zimagwiritsidwa ntchito / thanzi la Apigenein ndi monga:

• Atha kuchepetsa kukhumudwa/nkhawa komanso kusowa tulo (kusagona tulo)
• Itha kukhala ndi zotsatira za anti-diabetes
• Itha kukhala ndi neuroprotective effect
• Mutha kukhala ndi zida zotsutsa khansa
• Zitha kuthandiza kuchepetsa kuthamanga kwa magazi

Anti-Cancer Effects/Ubwino wa Apigenin

Mfundo zazikuluzikulu zachitika pamitundu yosiyanasiyana ya khansa ma cell ndi zitsanzo za nyama zogwiritsa ntchito Apigenin zawonetsa zotsatira zake zotsutsana ndi khansa. Kukongola kwa ma flavonoids ngati Apigenin ndikuti sikungothandiza popewera khansa kuti achepetse chiopsezo chamtsogolo chokhala ndi chotupa, komanso amatha kugwira ntchito mogwirizana ndi ma chemotherapies kuti apititse patsogolo mphamvu ya mankhwalawa.Yan et al, Cell Biosci., 2017).

Zitsanzo Zochepa Zotsutsana ndi Khansa ya Apigenin

Zina mwa zitsanzo za khansa zopewera za Apigenin ndi mgwirizano wake ndi chemotherapy mumitundu ina ya khansa zafotokozedwa pansipa.

Zotsatira za Apigenin mu Khansa ya Gastro-M'mimba

Pankhani ya khansa ya m'mimba, Apigenin adapezeka kuti amayambitsa kufa kwa maselo ndikulepheretsa kukula kwa mitsempha yatsopano yomwe imathandiza chotupacho kukula. Kuphatikiza apo, Apigenin idapangitsa kuti chilengedwe cha chotupacho chikhale choyipa kwambiri pochepetsa kutengeka kwa shuga ndi maselo a khansa, kusokoneza kukonzanso kwa matrix kunja ndi kuzungulira cell ya khansa, ndikuletsa njira zomwe zimathandizira kukula kwa khansa ndikufalikira.Lefort EC et al, Mol Nutr Food Res., 2013). 

Zotsatira za kumwa Apigenin pamodzi ndi Gemcitabine Chemotherapy ya Pancreatic Cancer - Maphunziro Oyesera

• Kafukufuku wa labotale wopangidwa ndi ofufuza ochokera ku Seoul National University College of Medicine ku Korea adapeza kuti apigenin imakulitsa mphamvu ya anti-tumor ya gemcitabine mu khansa ya kapamba. (Lee SH et al, Cancer Lett., 2008)
• Kafukufuku wina wopangidwa ndi ofufuza a Feinberg School of Medicine ku Chicago adapezanso kuti kugwiritsa ntchito apigenin limodzi ndi gemcitabine kumalepheretsa kukula kwa khansa ya kapamba ndikupangitsa kufa kwa maselo a khansa (apoptosis). (Strouch MJ et al, Pancreas, 2009)

Mwachidule, kafukufuku wambiri pogwiritsa ntchito chikhalidwe cha maselo ndi zinyama adapeza kuti Apigenin imapangitsa kuti gemcitabine chemotherapy ikhale yovuta pochiza khansa ya kapamba.

Zotsatira za kumwa Apigenin pamodzi ndi Cisplatin Chemotherapy - Maphunziro Oyesera

Mu kafukufuku wopangidwa ndi ofufuza ochokera ku yunivesite ya Trakya ku Turkey, Apigenin ataphatikizidwa ndi mankhwala a chemo a Cisplatin adakulitsa kwambiri mphamvu yake ya cytotoxic m'maselo a khansa ya prostate (anti-cancer effect of Apigenin), ndipo machitidwe a maselo a Apigenin adatsimikiziridwa. (Erdogan S et al, Biomed Pharmacother., 2017).

Kutsiliza

Kafukufuku wosiyanasiyana akuwonetsa kuthekera kwa anti-cancer / phindu la apigenin. Komabe, zotsatira za maphunziro oyeserawa sizimatsimikiziridwa m'mayesero aumunthu. Komanso, pochenjeza, kuti mankhwala achilengedwe monga Apigenin amatha kukhudza kwambiri ma cell a cell amatanthauzanso kuti amatha kukhala ndi zotsatira zoyipa pamankhwala a khansa ngati atagwiritsidwa ntchito molakwika ndi mankhwala a chemo. Kuphatikiza apo, Apigenin kukhala antioxidant imatha kusokoneza mankhwala a chemo omwe amagwiritsa ntchito njira yowonjezeretsa kuwonongeka kwa ma cell a khansa akamatengedwa nthawi imodzi ndi chemo, pomwe kafukufuku wasonyeza kuti chithandizo chamankhwala ndi Apigenin chisanachitike chemo chinali ndi zotsatira zabwino. Choncho, m'pofunika kuti khansa odwala nthawi zonse amafunsana ndi akatswiri awo azaumoyo pazakudya komanso kugwiritsa ntchito mankhwala owonjezera achilengedwe akamapatsidwa mankhwala amphamvu m'malo mosankha mwachisawawa potengera zomwe achibale awo komanso anzawo anganene.

Chakudya chomwe mumadya komanso chomwe chimakupatsani thanzi ndi chisankho chomwe mumapanga. Lingaliro lanu liyenera kuphatikizapo kulingalira za kusintha kwa majini a khansa, khansa, chithandizo chamankhwala chopitilira muyeso, zovuta zilizonse, zidziwitso za moyo, kulemera, kutalika ndi zizolowezi.

Kukonzekera kwa khansa kuchokera ku addon sikudalira pakusaka kwa intaneti. Zimakusankhirani zomwe mungasankhe malinga ndi sayansi yamayendedwe omwe asayansi athu ndi akatswiri a mapulogalamu. Mosasamala kanthu kuti mumasamala kumvetsetsa zomwe zimayambira zamagulu am'thupi kapena ayi - pakukonzekera zakudya za khansa kumvetsetsa kumafunikira.

Yambirani TSOPANO ndikukonzekera zakudya zanu poyankha mafunso okhudzana ndi khansa, kusintha kwa majini, mankhwala opitilira muyeso ndi zowonjezera, chifuwa chilichonse, zizolowezi, moyo, gulu la zaka komanso jenda.

Odwala khansa nthawi zambiri amakhala ndi zovuta zosiyanasiyana chemotherapy mavuto zomwe zimakhudza moyo wawo ndikuyang'ana njira zina zochiritsira khansa. Kutenga chakudya choyenera ndi zowonjezera zowonjezera kutengera zomwe asayansi amalingalira (kupewa kuyerekezera ndi kusankha mwachisawawa) ndiye njira yabwino kwambiri yachilengedwe ya khansa ndi zovuta zina zokhudzana ndi chithandizo.

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