highlights
Kev tshawb pom los ntawm cov kev tshawb fawb sib txawv tau qhia tias kev noj cov hlau ntau dhau / heme hlau yuav ua rau muaj kev pheej hmoo rau mob qog noj ntshav xws li Cancer Cancer thiab Pancreatic Cancer; Txawm li cas los xij, tag nrho cov hlau tau txais los yog cov hlau tsis muaj heme yuav muaj kev tiv thaiv kab mob qog noj ntshav thiab esophageal. Raws li cov kev tshawb fawb soj ntsuam hauv qhov blog no, hauv Cancer xws li mob ntsws cancer thiab mob qog nqaij hlav prostate, tsis pom muaj kev koom tes tseem ceeb. Cov kev tshawb fawb zoo tshaj plaws yog xav tau los tsim cov kev tshawb pom no. Iron supplements intake with Erythropoiesis-stimulating agents for cancer chemotherapy-induced anemia (low hemoglobin levels) tej zaum yuav muaj qee yam txiaj ntsig. Txawm hais tias kev noj zaub mov kom zoo yog qhov tseem ceeb rau kev ua haujlwm ntawm peb lub cev, nws qhov kev noj ntau dhau tuaj yeem ua rau muaj kev phiv thiab tuaj yeem ua rau tuag taus rau menyuam yaus. Yog li ntawd, nrog ib tus kws kho mob ua ntej noj cov zaub mov muaj hlau.
Hlau - Qhov tseem ceeb khoom noj khoom haus
Hlau yog ib qho tseem ceeb ntxhia uas tseem ceeb heev rau kev ua haujlwm ntawm hemoglobin kom zoo, cov protein uas yuav tsum tau thauj cov pa oxygen hauv cov ntshav, thiab rau kev loj hlob thiab kev loj hlob. Ua ib qho khoom noj tseem ceeb, hlau yuav tsum tau txais los ntawm peb cov khoom noj. Nws kuj tseem ua lub luag haujlwm tseem ceeb hauv ntau lwm cov txheej txheem xws li tsim cov serotonin, cov leeg ua haujlwm, lub zog tsim khoom, cov txheej txheem hauv plab hnyuv, kev tswj hwm ntawm lub cev kub, DNA synthesis thiab txhawb kev tiv thaiv kab mob.
Hlau feem ntau khaws cia hauv daim siab thiab pob txha pob txha li ferritin lossis hemosiderin. Nws kuj tseem tuaj yeem khaws cia hauv spleen, duodenum thiab cov leeg pob txha.
Khoom noj khoom haus ntawm Hlau
Qee qhov piv txwv ntawm cov khoom noj ntawm cov hlau muaj xws li:
- Liab Nqaij
- siab
- Taum
- Ceev
- Cov txiv hmab txiv ntoo qhuav xws li cov hnub qhuav thiab apricots
- Taum taum
Hom Kev Noj Qab Haus Huv Hlau
Dietary hlau muaj nyob rau hauv ob hom:
- Hlau hlau
- Tsis muaj hlau
Heme hlau muaj kwv yees li 55-70% ntawm tag nrho cov hlau los ntawm cov khoom tsiaj xws li nqaij liab, nqaij qaib thiab ntses thiab muaj kev ua haujlwm zoo dua ntawm kev nqus.
Cov hlau uas tsis yog-heme muaj xws li cov hlau thiab cov hlau uas muaj nyob hauv cov khoom noj xws li legumes thiab cereals, thiab cov khoom siv hlau. Nws yog ib qho nyuaj rau nqus hlau los ntawm cov khoom noj uas cog qoob loo. Thov nco ntsoov tias kev siv cov vitamin C yuav pab kom nqus tau cov hlau.
Hlau Deficiency
Cov hlau tsis muaj peev xwm, hu ua anemia, yog ib qho mob uas tsis muaj hlau nyob hauv lub cev ua rau cov qe ntshav liab noj qab haus huv tsawg dua uas tuaj yeem nqa oxygen mus rau cov ntaub so ntswg.
Qhov pom zoo pub nyiaj txhua hnub ntawm Iron txawv raws hnub nyoog thiab poj niam txiv neej:
- 8.7mg ib hnub rau cov txiv neej tshaj 18 xyoo
- 14.8mg ib hnub rau cov poj niam hnub nyoog 19 txog 50
- 8.7mg ib hnub rau cov poj niam tshaj 50
Cov nyiaj no feem ntau tuaj yeem tau los ntawm peb cov khoom noj.
Hlau deficiency yog qhov tsis muaj zaub mov ntau tshaj plaws hauv ntiaj teb. Yog li ntawd, yav tas los tsom ntsoov rau kev noj zaub mov muaj hlau ntau dua rau cov tsis muaj hlau. Txawm li cas los xij, yav dhau los tsis ntev los no, cov kws tshawb fawb kuj tau tshawb nrhiav qhov cuam tshuam ntawm cov hlau ntau hauv lub cev. Hauv blog no, peb yuav tsom mus rau qee qhov kev tshawb fawb uas ntsuas kev sib koom ua ke ntawm cov hlau thiab kev pheej hmoo ntawm ntau hom qog noj ntshav.
Cov zaub mov noj tom qab kuaj mob qog noj ntshav!
Tsis muaj ob yam mob qog noj ntshav zoo ib yam. Mus dhau qhov txheej txheem kev noj zaub mov zoo rau txhua tus thiab txiav txim siab tus kheej txog zaub mov thiab tshuaj ntxiv nrog kev ntseeg siab.
Kev koom tes ntawm Iron thiab Breast Cancer Risk
Serum thiab qog nqaij hlav hlau thiab mob cancer mis
Ib qho kev ntsuam xyuas meta-ua los ntawm cov kws tshawb fawb los ntawm Golestan University of Medical Sciences, Ilam University of Medical Sciences, Shahid Beheshti University of Medical Sciences thiab Birjand University of Medical Sciences tau soj ntsuam kev koom tes ntawm cov hlau thiab kev pheej hmoo mob qog noj ntshav. Cov kev tshuaj xyuas suav nrog 20 kab lus (suav nrog 4,110 tus neeg nrog 1,624 tus neeg mob qog noj ntshav mis thiab 2,486 kev tswj hwm) uas tau luam tawm thaum xyoo 1984 thiab 2017 thiab tau los ntawm kev tshawb fawb cov ntaub ntawv hauv PubMed, Scopus, Embase, Web of Science, thiab Cochrane Library. (Akram Sanagoo et al, Caspian J Intern Med., Lub caij ntuj no 2020)
Kev tshuaj ntsuam pom pom muaj kev pheej hmoo siab ntawm mob qog noj ntshav nrog cov hlau ntau hauv cov pab pawg uas ntsuas hlau hauv cov ntaub so ntswg ntawm lub mis. Txawm li cas los xij, lawv tsis pom muaj kev sib raug zoo ntawm cov hlau concentration thiab lub mis cancer txaus ntshai nyob rau hauv cov pab pawg uas tau ntsuas hlau nyob rau hauv tawv taub hau plaub hau.
Kev noj cov hlau, lub cev hlau, thiab kev pheej hmoo mob qog noj ntshav mis
Cov kws tshawb fawb los ntawm University of Toronto thiab Cancer Care Ontario, Canada tau ua ib qho kev tshuaj ntsuam xyuas los ntsuas cov kev sib koom ua ke ntawm ob qho tib si ntawm kev noj hlau thiab lub cev hlau thiab kev pheej hmoo mob qog noj ntshav. 23 cov kev tshawb fawb tau suav nrog rau kev tshuaj xyuas tom qab kev tshawb fawb cov ntaub ntawv hauv MEDLINE, EMBASE, CINAHL, thiab Scopus databases txog Lub Kaum Ob Hlis 2018. (Vicky C Chang li al, BMC Cancer., 2019)
Lawv pom tias thaum piv rau cov neeg uas tau txais heme hlau qis tshaj plaws, muaj 12% nce hauv kev pheej hmoo mob qog noj ntshav hauv cov neeg uas muaj heme hlau ntau tshaj. Txawm li cas los xij, lawv tsis pom muaj kev koom tes tseem ceeb ntawm kev noj haus, ntxiv lossis tag nrho cov hlau kom tsawg thiab muaj feem yuav mob qog noj ntshav. Cov kev tshawb fawb soj ntsuam zoo ntxiv yog xav tau los ua kom paub tseeb txog kev sib raug zoo ntawm cov hlau thiab kev pheej hmoo mob qog noj ntshav mis.
Kev cuam tshuam ntawm Antioxidant Supplementation ntawm kev koom tes ntawm kev noj zaub mov noj hlau thiab kev pheej hmoo mob qog noj ntshav mis
Ib txoj kev tshawb fawb ua los ntawm cov kws tshawb fawb hauv Fab Kis xyoo 2016 tau soj ntsuam kev sib koom ua ke ntawm kev noj zaub mov noj hlau thiab kev pheej hmoo mob qog noj ntshav ntawm lub mis, thiab nws qhov kev hloov pauv muaj peev xwm los ntawm kev siv tshuaj tua kab mob antioxidant thiab lipid kom tsawg hauv 4646 tus poj niam los ntawm SU.VI.MAX mus sib hais. Thaum lub sij hawm nruab nrab ntawm kev soj ntsuam ntawm 12.6 xyoo, 188 tus mob cancer mis tau tshaj tawm. (Abou Diallo li al, Oncotarget., 2016)
Txoj kev tshawb nrhiav pom tias kev noj zaub mov muaj hlau tau cuam tshuam nrog kev pheej hmoo mob qog noj ntshav ntawm lub mis, tshwj xeeb tshaj yog nyob rau hauv cov poj niam uas tau noj cov lipids ntau dua, txawm li cas los xij, lub koom haum no tau pom tsuas yog rau cov neeg uas tsis tau ntxiv nrog cov tshuaj antioxidants thaum lub sijhawm sim. Txoj kev tshawb no xaus lus tias kev pheej hmoo mob qog noj ntshav mis yuav tau nce ntxiv los ntawm cov hlau-induced lipid peroxidation.
NIH-AARP Kev Noj Qab Haus Huv thiab Kev Tshawb Fawb Txog Kev Noj Qab Haus Huv
Hauv lwm qhov kev tshuaj xyuas ntawm cov ntaub ntawv noj zaub mov los ntawm 193,742 cov poj niam tom qab yug menyuam uas yog ib feem ntawm NIH-AARP Kev Noj Qab Haus Huv thiab Kev Tshawb Fawb Txog Kev Noj Qab Haus Huv, nrog rau 9,305 qhov xwm txheej mob qog noj ntshav tau txheeb xyuas (1995-2006), nws tau pom tias kev noj cov hlau heme siab tau cuam tshuam nrog kev mob qog noj ntshav. nce kev pheej hmoo ntawm mob qog noj ntshav mis, tag nrho thiab ntawm txhua theem mob qog noj ntshav. (Maki Inoue-Choi et al, Int J Cancer., 2016)
Kev sib koom ua ke ntawm Iron thiab Colorectal Cancer Risk
Iron Intake, Serum Iron Indices thiab Risk of Colorectal Adenomas
Cov kws tshawb fawb los ntawm Zhejiang Provincial Cov Tsev Kho Mob thiab Thawj Cov Tsev Kho Mob ntawm Fuyang District hauv Suav teb, tau soj ntsuam kev sib koom ua ke ntawm kev noj cov hlau, cov piam thaj hauv cov ntshav thiab cov kev pheej hmoo ntawm kev mob plab adenoma, siv cov ntaub ntawv los ntawm 10 kab lus, suav nrog 3318 tus neeg mob plab adenoma, tau los ntawm cov ntaub ntawv. nrhiav hauv MEDLINE thiab EMBASE txog 31 Lub Peb Hlis 2015. (H Cao et al, Eur J Cancer Care (Engl)., 2017)
Txoj kev tshawb nrhiav pom tias kev noj zaub mov ntau ntxiv ntawm heme hlau yog cuam tshuam nrog kev pheej hmoo ntawm cov kab mob hauv lub plab adenoma, thaum noj cov hlau tsis muaj heme los yog cov hlau ntxiv txo qhov kev pheej hmoo ntawm cov pob txha adenomas. Raws li cov ntaub ntawv txwv tsis pub muaj, tsis muaj kev sib koom ua ke ntawm cov piam thaj hauv cov ntshav thiab qhov kev pheej hmoo ntawm kev mob plab adenoma.
Kev noj cov tshuaj heme hlau thiab zinc thiab mob qog noj ntshav hauv plab
Ib txoj kev tshawb fawb ua los ntawm cov kws tshawb fawb los ntawm Shengjing Tsev Kho Mob ntawm Tuam Tshoj Medical University hauv Suav teb tau soj ntsuam cov kev sib koom ua ke ntawm kev noj cov heme hlau thiab zinc thiab cov pob qij txha. cancer xwm txheej. Yim qhov kev tshawb fawb txog heme hlau kom tsawg thiab rau qhov kev tshawb fawb txog zinc kom tsawg tau siv rau kev soj ntsuam uas tau los ntawm kev tshawb nrhiav cov ntaub ntawv hauv PubMed thiab EMBASE databases txog rau lub Kaum Ob Hlis 2012. (Lei Qiao li al, Cancer Causes Control., 2013)
Qhov kev tshuaj ntsuam meta no tau pom tias muaj kev pheej hmoo mob qog noj ntshav hauv plab hnyuv loj nrog nce heme hlau kom tsawg thiab txo qis hauv kev pheej hmoo mob qog nqaij hlav hauv plab nrog nce zinc kom tsawg.
Kev sib koom ua ke ntawm Iron thiab Esophageal Cancer Risk
Cov kws tshawb fawb los ntawm Zhengzhou University thiab Zhejiang University Tsev Kawm Ntawv Tshuaj Kho Mob hauv Suav teb tau ua qhov kev tshuaj ntsuam xyuas meta-kev ntsuas kev sib koom ua ke ntawm kev noj cov hlau tag nrho thiab zinc thiab qis heme hlau thiab kev pheej hmoo ntawm Esophageal Cancer. Cov ntaub ntawv rau kev tshuaj xyuas tau txais los ntawm 20 kab lus nrog 4855 tus neeg mob los ntawm 1387482 tus neeg koom, tau los ntawm kev tshawb fawb cov ntaub ntawv hauv Embase, PubMed, thiab Web of Science databases txog lub Plaub Hlis 2018. (Jifei Ma e al, Nutr Res., 2018)
Txoj kev tshawb nrhiav pom tias txhua txhua 5 mg / hnub nce ntxiv ntawm tag nrho cov hlau tau txuam nrog 15% txo kev pheej hmoo ntawm Esophageal Cancer. Qhov kev pheej hmoo txo tau pom tshwj xeeb hauv cov neeg Esxias. Hloov pauv, txhua txhua 1 mg / hnub nce hauv heme hlau kom tsawg tau cuam tshuam nrog 21% nce hauv Esophageal Cancer.
Kev sib koom ua ke ntawm Iron thiab Pancreatic Cancer Risk
Ib txoj kev tshawb fawb luam tawm xyoo 2016 tau soj ntsuam kev sib koom ua ke ntawm kev noj cov nqaij, cov nqaij ua noj thiab ua tiav thiab heme hlau thiab mutagen noj nrog pancreatic cancer hauv NIH-AARP Kev Noj Qab Haus Huv thiab Kev Tshawb Fawb Kev Noj Qab Haus Huv nrog 322,846 tus neeg koom nrog uas 187,265 yog txiv neej thiab 135,581 yog poj niam. Tom qab kev soj ntsuam raws li 9.2 xyoo, 1,417 pancreatic cancer cov xwm txheej tau tshaj tawm. (Pulkit Taunk et al, Int J Cancer., 2016)
Txoj kev tshawb nrhiav pom tias mob qog noj ntshav muaj peev xwm nce ntxiv nrog rau kev noj tag nrho cov nqaij, nqaij liab, kub-kub nqaij siav, grilled / barbequed nqaij, zoo / ua tau zoo heev nqaij thiab heme hlau los ntawm cov nqaij liab. Cov kws tshawb fawb tau tawm tswv yim ntau cov kev tshawb fawb kom paub meej tias lawv qhov kev tshawb pom.
Kev sib koom ua ke ntawm Iron thiab Prostate Cancer Risk
Hauv kev tshawb fawb luam tawm los ntawm cov kws tshawb fawb los ntawm EpidStat Institutes hauv Michigan thiab Washington hauv Teb Chaws Asmeskas, lawv tau soj ntsuam kev sib koom ua ke ntawm cov nqaij ua noj, heme hlau, thiab heterocyclic amine (HCA) noj thiab mob qog noj ntshav raws li 26 cov ntawv tshaj tawm los ntawm 19 cov kev tshawb fawb sib txawv. . (Lauren C Bylsma et al, Nutr J., 2015)
Lawv qhov kev soj ntsuam tsis pom muaj kev sib koom ua ke ntawm cov nqaij liab lossis cov nqaij ua tiav thiab mob qog nqaij hlav prostate; Txawm li cas los xij, lawv pom muaj kev pheej hmoo me me nrog kev noj cov nqaij ua tiav.
Kev sib koom ua ke ntawm Cov Qib Iron Levels thiab Mob ntsws Cancer Risk
Ib txoj kev tshawb fawb los ntawm cov kws tshawb fawb los ntawm Tsev Kho Mob Zhejiang Rongjun, Zhejiang Cancer Tsev Kho Mob, Fujian Medical University Cancer Tsev Kho Mob thiab Lishui Tsev Kho Mob ntawm Zhejiang University hauv Suav teb tau soj ntsuam kev sib koom ua ke ntawm qib hlau hlau thiab kev pheej hmoo mob qog noj ntshav. Cov ntaub ntawv rau kev tshuaj xyuas tau muab los ntawm PubMed, WanFang, CNKI, thiab SinoMed cov ntaub ntawv mus txog Lub Peb Hlis 1, 2018. Txoj kev tshawb fawb pom tias cov qib hlau hauv cov ntshav tsis muaj feem cuam tshuam nrog kev pheej hmoo mob qog noj ntshav. (Hua-Fei Chen et al, Cell Mol Biol (Noisy-le-grand)., 2018)
Kev Siv Cov Khoom Siv Hlau Hauv Kev Tswj Xyuas Tshuaj Khomob-induced Anemia (tsawg hemoglobin) hauv Cov Neeg Mob Cancer
Ib txoj kev tshawb fawb los ntawm Lub Tsev Haujlwm Saib Xyuas Kev Tshawb Fawb thiab Kev Tshawb Fawb Txog Kev Noj Qab Haus Huv, University of South Florida, Tampa, Florida, Tebchaws Asmeskas tau soj ntsuam cov txiaj ntsig thiab kev phom sij ntsig txog kev siv cov tshuaj hlau nrog rau Erythropoiesis-stimulating agents (ESAs), uas feem ntau siv. los kho mob kheesxaws chemotherapy-induced anemia (tsawg hemoglobin qib) - CIA, thiab Cochrane Database Syst hlau ib leeg piv nrog ESA ib leeg hauv kev tswj hwm CIA. (Rahul Mhaskar et al, Rev., 2016) Txoj kev tshawb fawb pom tau hais tias suav nrog cov tshuaj ntxiv hlau nrog rau ESAs rau kev kho mob qog noj ntshav uas ua rau mob ntshav qab zib tuaj yeem ua rau cov lus teb hematopoietic zoo dua, txo qis kev pheej hmoo ntawm cov ntshav ntshav ntshav, thiab txhim kho cov qib hemoglobin tsawg.
Yog li, kev noj cov hlau ntxiv tuaj yeem muaj txiaj ntsig zoo rau cov neeg mob qog noj ntshav uas muaj tshuaj kho mob ntshav qab zib (tsawg hemoglobin).
xaus
Cov kev tshawb fawb no pom tias muaj kev cuam tshuam ntawm cov hlau sib txawv Cancer. Cov hlau ntau dhau tau pom tias yog qhov muaj feem cuam tshuam rau cov qog nqaij hlav xws li Cancer Cancer thiab Pancreatic Cancer, tejzaum nws vim nws cov kev ua oxidant uas tuaj yeem ua rau oxidative DNA puas; Txawm li cas los xij, tag nrho cov hlau tau txais thiab tsis-heme hlau tau txais, tau pom tias muaj kev tiv thaiv kab mob qog noj ntshav thiab esophageal. Hauv cov qog nqaij hlav xws li mob ntsws cancer thiab mob qog nqaij hlav prostate, tsis muaj kev koom tes tseem ceeb tau tshaj tawm. Iron supplements nrog rau ESAs rau kev kho mob kheesxaws-xws li ntshav ntshav (tsis tshua muaj hemoglobin) yuav pab tau. Txawm hais tias kev noj zaub mov kom zoo yog qhov tseem ceeb rau kev ua haujlwm ntawm peb lub cev, nws qhov kev noj ntau dhau ntawm cov tshuaj yuav ua rau muaj kev phiv xws li cem quav thiab mob plab thiab tuaj yeem ua rau tuag taus rau menyuam yaus. Yog li ntawd, sab laj nrog kws kho mob ua ntej noj cov tshuaj hlau. Qhov xav tau ntawm cov hlau tuaj yeem tau los ntawm cov khoom noj.
Yam zaub mov twg koj noj thiab cov khoom noj uas koj noj yog qhov kev txiav txim siab koj ua. Koj qhov kev txiav txim siab yuav tsum suav nrog kev txiav txim siab ntawm kev hloov pauv noob caj noob ces, uas mob qog noj ntshav, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua qhov ua xua, qhia txog kev ua neej nyob, hnyav, qhov siab thiab tus cwj pwm.
Kev npaj zaub mov noj rau mob qog noj ntshav los ntawm addon tsis yog los ntawm kev tshawb fawb hauv internet. Nws siv qhov kev txiav txim siab rau koj raws li kev tshawb fawb molecular siv los ntawm peb cov kws tshawb fawb thiab software engineers. Tsis hais seb koj puas mob siab rau nkag siab cov hauv paus txheej txheem biochemical molecular lossis tsis - rau kev npaj zaub mov noj rau mob qog noj ntshav uas xav tau kev nkag siab.
Pib tam sim no nrog koj cov phiaj xwm kev noj zaub mov zoo los ntawm kev teb cov lus nug ntawm lub npe mob qog noj ntshav, kev hloov pauv caj ces, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua yam kev ua xua, tus cwj pwm, lub neej, pab pawg hnub nyoog thiab poj niam txiv neej.
Khoom noj khoom haus tus kheej rau Cancer!
Cancer hloov nrog lub sijhawm. Kho thiab hloov kho koj cov khoom noj khoom haus raws li kev qhia mob qog noj ntshav, kev kho mob, kev ua neej, kev nyiam zaub mov, kev ua xua thiab lwm yam.
Cov neeg mob cancer feem ntau yuav tsum tau ua nrog sib txawv kev kho mob tshuaj phiv uas cuam tshuam rau lawv lub neej zoo thiab saib rau lwm cov kev kho mob qog noj ntshav. Noj cov khoom noj khoom haus zoo thiab pabcuam ntxiv raws li kev txiav txim siab science (Tsis txhob twv thiab xaiv xaiv) yog cov tshuaj zoo tshaj plaws rau mob qog noj ntshav thiab kho mob cuam tshuam nrog kev phiv.