highlights
Ib daim ntawv qhib, ib lub koom haum, theem kuv kawm ua los ntawm cov kws tshawb fawb los ntawm Nyij Pooj tau hais tias ib hnub koob tshuaj 12 g ntawm GBS-01, muaj kwv yees li 4g burdock txiv hmab txiv ntoo extract nplua nuj nyob rau hauv arctigenin, tej zaum yuav muaj kev nyab xeeb thiab tej zaum yuav muaj txiaj ntsig zoo hauv cov neeg mob uas muaj mob pancreatic cancer refractory rau Gemcitabine therapy. Txawm li cas los xij, cov kev sim loj loj uas tau hais tseg yuav tsum tau tsim los tsim cov kev tshawb pom no.
Burdock thiab nws Txoj Kev Sib Raug
Arctium lappa, feem ntau hu ua burdock, yog tsob nroj uas ib txwm muaj rau Asia thiab Europe. Burdock yog tam sim no nrov thoob ntiaj teb thiab tau cog thiab siv los ua zaub hauv ntau qhov chaw ntawm lub ntiaj teb. Cov hauv paus hniav, nplooj thiab noob ntawm cov nroj tsuag no yog siv hauv Cov Tshuaj Hauv Tebchaws Suav los ua tshuaj kho rau ntau yam mob. Cov hauv paus hniav Burdock tau ntim nrog tshuaj tua kab mob antioxidant thiab kuj tau suav tias yog muaj tshuaj los tiv thaiv qog.
Cov kev tshawb fawb sib txawv hais txog yav dhau los tau qhia tias burdock yuav muaj kev tiv thaiv kev tiv thaiv, tua kab mob, tiv thaiv kab mob, antiulcerogenic, hepatoprotective, thiab anticancer cov yam ntxwv. Lub tebchaw tseem ceeb ntawm burdock cia suav nrog caffeoylquinic acid derivatives, lignans thiab ntau yam flavonoids.
Cov nplooj ntawm burdock feem ntau muaj ob hom lignans:
- Arctiin
- Arctigenin
Sib nrug ntawm cov no, cov phenolic acids, quercetin, quercitrin thiab luteolin kuj tseem muaj nyob hauv nplooj nraws.
Cov noob Burdock muaj cov phenolic acids xws li Caffeic acid, Chlorogenic acid thiab Cynarin.
Lub tebchaw tseem ceeb hauv Burdock cag yog Arctiin, Luteolin thiab Quercetin rhamnoside uas tuaj yeem ua rau lawv muaj peev xwm tiv thaiv mob qog noj ntshav.
Kev Siv Cov Dab Tsi Ntawm Burdock Extract
Burdock tau siv dav dav hauv Suav Tshuaj hauv Suav rau cov laj thawj hauv qab no, txawm hais tias tsis muaj pov thawj dab tsi los txhawb nws qhov kev siv rau ntau yam mob no:
- Purifying cov ntshav
- Txo ntshav siab
- Txo gout
- Txo cov kab mob siab
- Txo cov kab mob microbial
- Txo cov ntshav qab zib hauv cov neeg mob ntshav qab zib
- Kho cov tawv nqaij muaj teeb meem xws li eczema thiab psoriasis
- Txo wrinkles
- Kho cov mob cuam tshuam
- Kho Cov Mob AIDS
- Kho Cancer
- Raws li cov diuretic
- Raws li antipyretic tshuaj yej rau kev kho mob kub taub hau
Cov zaub mov noj tom qab kuaj mob qog noj ntshav!
Tsis muaj ob yam mob qog noj ntshav zoo ib yam. Mus dhau qhov txheej txheem kev noj zaub mov zoo rau txhua tus thiab txiav txim siab tus kheej txog zaub mov thiab tshuaj ntxiv nrog kev ntseeg siab.
Yuav Burdock Extracts Pab Tau Pancreatic Cancer cov neeg mob refractory rau Gemcitabine?
Raws li American Cancer Society, mob qog nqaij hlav pancreatic yog cuaj feem ntau cancer Hauv cov poj niam thiab thib kaum feem ntau mob qog noj ntshav hauv cov txiv neej thiab suav txog 7% ntawm tag nrho cov mob qog noj ntshav.
Nws tseem yog qhov thib plaub ua rau muaj mob cancer tuag taus rau txiv neej thiab poj niam.
Gemcitabine yog tus qauv ua ntej-kab tshuaj kho mob rau tus kabmob qog nqaij hlav. Txawm li cas los xij, kab mob pancreatic cancer microenvironment paub zoo tias yuav muaj cov yam ntxwv ntawm hypoxia, qhov mob uas lub cev tsis txaus ua kom muaj pa oxygen txaus nyob rau ntawm daim ntaub so ntswg, thiab kev noj zaub mov tsis zoo, tshwj xeeb tshaj yog cov piam thaj. Hypoxia ua rau kom muaj zog ntawm cov tshuaj tiv thaiv kab mob gemcitabine, yog li ua rau cov txiaj ntsig zoo ntawm cov tshuaj tua kab mob no.
Li no, cov kws tshawb nrhiav los ntawm National Cancer Center Tsev Kho Mob Sab Hnub Tuaj, Meiji Pharmaceutical University, National Cancer Center, Kracie Pharma, Ltd. hauv Toyama, thiab Tokyo University of Science, Nyijpooj tau soj ntsuam cov sib txawv sib txawv uas tuaj yeem pom kev ua siab ntev rau cov qog ntshav qog ntshav qab zib mus rau cov ntshav qab zib thiab hypoxia, thiab txheeb xyuas arctigenin, ib qho tseem ceeb sib xyaw pom hauv Burdock extracts, yog qhov zoo tshaj plaws tus neeg sib tw rau kev kuaj mob, vim nws cov kev ua haujlwm tiv thaiv kab mob pom muaj nyob hauv ntau xenograft cov qauv mob qog noj ntshav thiab muaj kev nyab xeeb txaus thaum muab ntawm koob tshuaj ntau txog 100 lub sijhawm txhua hnub koob tshuaj yuav tsum muaj rau kev ua haujlwm tiv thaiv kab mob hauv nas. (Masafumi Ikeda li al, Cancer Sci., 2016)
Cov kws tshawb fawb tau siv cov tshuaj hauv qhov ncauj GBS-01, ib qho extract los ntawm cov txiv hmab txiv ntoo ntawm Burdock, nplua nuj nyob rau hauv arctigenin, nyob rau hauv 15 cov neeg mob nrog pancreatic siab heev. cancer refractory rau gemcitabine. Hauv kev sim, lawv tau tshawb xyuas qhov siab tshaj plaws ntawm koob tshuaj GBS-01 thiab saib xyuas rau Dose-limiting toxicities. Dose-limiting toxicities (DLTs) yog hais txog cov tsos mob ntawm qib 4 hematological / ntshav toxicity thiab qib 3 lossis 4 uas tsis yog hematological / ntshav toxicity thaum thawj 28 hnub ntawm kev kho mob.
Hauv txoj kev tshawb nrhiav, lawv pom tias tsis muaj cov cim ntawm qib 4 ntshav toxicities thiab qib 3 lossis 4 tsis muaj tshuaj lom ntshav nyob hauv ib qho ntawm cov neeg mob tau tso npe, ntawm ib qho ntawm peb koob tshuaj uas tau siv (txhua hnub 3.0 g, 7.5 g lossis 12.0 g) Cov. Txawm li cas los xij, cov tshuaj lom me me tau pom tias muaj xws li nce ntshav ntau ntxiv glutamyl transpeptidase, ntshav nce ntxiv, thiab cov ntshav ntau ntxiv bilirubin.
Txoj kev tshawb nrhiav tau txiav txim pom zoo koob tshuaj pom zoo ntawm GBS ‐ 01, cov extract nplua nuj nyob hauv arctigenin los ntawm Burdock, yuav tsum yog 12.0 g txhua hnub, vim tias tsis muaj DLTs tau pom ntawm ib qho ntawm peb koob. Qhov koob tshuaj txhua hnub ntawm 12.0 g GBS ‐ 01 tau kwv yees li ntawm 4.0 g burdock txiv hmab txiv ntoo extract.
Tawm ntawm cov neeg mob uas haus cov Burdock extract, 4 cov neeg mob tau mob ruaj khov thiab 1 pom tias teb ib nrab thaum lub sijhawm soj ntsuam. Yuav kom paub meej, cov lus teb tau yog 6.7% thiab tus nqi tiv thaiv kabmob yog 33.3%. Txoj kev tshawb no kuj pom tias qhov mob siab nruab nrab ‐ pub dawb thiab tag nrho kev ua neej nyob ntawm cov neeg mob yog 1.1 lub hlis thiab 5.7 hli, feem.
xaus
Burdock extracts thiab cov hauv paus hniav raug suav hais tias muaj tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, thiab tshuaj tiv thaiv kab mob. Ib xyoo 2016 theem kuv kev tshawb fawb soj ntsuam ua los ntawm cov kws tshawb fawb los ntawm Nyij Pooj tau pom tias ib hnub koob tshuaj 12 g ntawm GBS-01 (muaj kwv yees li 4.0 g burdock txiv hmab txiv ntoo extract nplua nuj nyob rau hauv arctigenin) yuav muaj kev nyab xeeb thiab tej zaum yuav muaj txiaj ntsig zoo rau cov neeg mob pancreatic siab. Cancer refractory rau Gemcitabine therapy. Txawm li cas los xij, ntau qhov kev txiav txim siab loj dua yog qhov tsim nyog los tsim cov kev tshawb pom no, ua ntej pom zoo siv arctigenin hauv cov neeg mob qog noj ntshav pancreatic.
Yam zaub mov twg koj noj thiab cov khoom noj uas koj noj yog qhov kev txiav txim siab koj ua. Koj qhov kev txiav txim siab yuav tsum suav nrog kev txiav txim siab ntawm kev hloov pauv noob caj noob ces, uas mob qog noj ntshav, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua qhov ua xua, qhia txog kev ua neej nyob, hnyav, qhov siab thiab tus cwj pwm.
Kev npaj zaub mov noj rau mob qog noj ntshav los ntawm addon tsis yog los ntawm kev tshawb fawb hauv internet. Nws siv qhov kev txiav txim siab rau koj raws li kev tshawb fawb molecular siv los ntawm peb cov kws tshawb fawb thiab software engineers. Tsis hais seb koj puas mob siab rau nkag siab cov hauv paus txheej txheem biochemical molecular lossis tsis - rau kev npaj zaub mov noj rau mob qog noj ntshav uas xav tau kev nkag siab.
Pib tam sim no nrog koj cov phiaj xwm kev noj zaub mov zoo los ntawm kev teb cov lus nug ntawm lub npe mob qog noj ntshav, kev hloov pauv caj ces, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua yam kev ua xua, tus cwj pwm, lub neej, pab pawg hnub nyoog thiab poj niam txiv neej.
Khoom noj khoom haus tus kheej rau Cancer!
Cancer hloov nrog lub sijhawm. Kho thiab hloov kho koj cov khoom noj khoom haus raws li kev qhia mob qog noj ntshav, kev kho mob, kev ua neej, kev nyiam zaub mov, kev ua xua thiab lwm yam.
Cov neeg mob cancer feem ntau yuav tsum tau ua nrog sib txawv kev kho mob tshuaj phiv uas cuam tshuam rau lawv lub neej zoo thiab saib rau lwm cov kev kho mob qog noj ntshav. Noj cov khoom noj khoom haus zoo thiab pabcuam ntxiv raws li kev txiav txim siab science (Tsis txhob twv thiab xaiv xaiv) yog cov tshuaj zoo tshaj plaws rau mob qog noj ntshav thiab kho mob cuam tshuam nrog kev phiv.