o ka Naauao
Ma kahi noiʻi liʻiliʻi liʻiliʻi i hana ʻia ma Kina, ua loiloi nā mea noiʻi i ka hoʻohana ʻana i ka Epigallocatechin-3-gallate (EGCG), he flavonoid i loaʻa i loko o ka mea inu kaulana loa - Green kī, i nā poʻe maʻi maʻi maʻi esophageal me ka mālama ʻana i ka radiation i hoʻokomo ʻia i nā pilikia ʻona (esophagitis). Ua ʻike lākou he pōmaikaʻi paha ʻo EGCG i ka hōʻemi ʻana i ka mālama ʻana i ka radiation i ka ʻai ʻana i nā pilikia i kēia mau maʻi i mālama ʻia me ka chemoradiation a i ʻole ka lāʻau radiation me ka ʻole o ka hopena maikaʻi ʻole i ka maikaʻi o kēia mau lāʻau lapaʻau. Hiki ke hoʻohana ʻia ke kī ʻōmaʻomaʻo, i lawe pinepine ʻia ma ke ʻano he meaʻai maikaʻi / meaʻai, e hōʻemi i nā hopena ʻaoʻao chemo-induced i ka esophageal Ka maʻi 'aʻai.
Hoʻokomo ʻia ka Esophagal Cancer a me ka hoʻomaʻamaʻa ʻana i ka uila
Ua manaʻo ʻia ʻo ka maʻi ʻaʻai esophage ka ʻehiku kumu maʻamau o Ka maʻi 'aʻai honua a he 5.3% o ka make maʻi maʻi ma ka honua holoʻokoʻa (GLOBOCAN, 2018). ʻO ka hoʻomaʻamaʻa ʻana a me ka chemoradiation (chemotherapy me ka radiation) nā lāʻau lapaʻau maʻamau i hoʻohana ʻia no ka maʻi maʻi esophageal. Eia nō naʻe, pili kēia mau lāʻau lapaʻau me nā hopena ʻaoʻao koʻikoʻi me ka acute radiation induced esophagitis (ARIE). ʻO ka esophagitis ka mumū o ka esophagus, kahi puʻupuʻu muscular hollow e hoʻopili ai i ka puʻu me ka ʻōpū. ʻO ka hoʻomaka ʻana o ka esophagitis i hoʻoulu ʻia e ka radiation acute (ARIE) hiki ke hana maʻamau i loko o 3 mau mahina ma hope o ka radiotherapy a hiki ke alakaʻi pinepine i nā pilikia ʻona / pilikia. No laila, ke ʻimi ʻia nei nā hoʻolālā like ʻole no ka hoʻomaha ʻana i nā pilikia o ka ʻai ʻana i ka radiation no ka mea he mea koʻikoʻi ia i nā oncologists no ka mālama pono ʻana i nā maʻi i hoʻopilikia ʻia.
Nā Mea ʻai e ʻAi ai Ma hope o ka ʻike maʻi ʻaʻai!
ʻAʻohe ʻelua maʻi ʻaʻai. E hele i waho o nā kulekele meaʻai maʻamau no kēlā me kēia kanaka a hoʻoholo i nā koho pilikino e pili ana i ka meaʻai a me nā mea hoʻopihapiha me ka hilinaʻi.
Ke aʻo e pili ana i ka hopena o ka Green Tea ʻeleu EGCG ma ka hoʻomaʻamaʻa ʻana i ka radiation radiophic i loko o Esophageal Cancer
ʻO ka Epigallocatechin-3-gallate (EGCG) he flavonoid me ka ikaika antioxidant a me nā waiwai anti-inflammatory a hoʻohana pū ʻia no ka hōʻemi ʻana i ka hopena o nā maʻi maʻi maʻi. ʻO ia kekahi o nā meaʻai nui loa i loaʻa i ke kī ʻōmaʻomaʻo a loaʻa pū i nā kī keʻokeʻo, oolong, a me nā ʻeleʻele. Ua alakaʻi ʻia kahi noiʻi lapaʻau ʻāpana II e nā mea noiʻi ma Shandong Cancer Hospital a me Institute ma Kina, e loiloi i ka hopena o uliuli kī ʻāpana EGCG (maʻa mau ʻia ma ke ʻano he ʻāpana o ka meaʻai olakino) ma ka chemoradiation/radiation treatment induced esophagitis (ka ʻai ʻana i nā pilikia) i nā maʻi maʻi maʻi esophageal i hoʻokomo ʻia ma waena o 2014 a 2016 (Xiaoling Li et al, Ka Nūpepa o nā Meaʻai Medicinal, 2019). Ua hoʻokomo ʻia he 51 mau maʻi i loko o ke aʻo ʻana, a mai loko mai o 22 mau maʻi i loaʻa i ka chemoradiation therapy (14 mau maʻi i mālama ʻia me ka docetaxel + cisplatin ukali ʻia e radiotherapy a me 8 me fluorouracil + cisplatin ukali ʻia e radiotherapy) a me 29 mau maʻi i loaʻa i ka radiation radiation a kiaʻi ʻia i kēlā me kēia pule no ka esophagitis hoʻokomo ʻia i ka radiation radiation (ARIE) / nā pilikia e ale. Hoʻoholo ʻia ka paʻakikī o ka ARIE me ka hoʻohana ʻana i ka Score Radiation Therapy Oncology Group (RTOG). Ua hoʻonui ʻia nā mea maʻi me ka helu 1 RTOG helu me 440 µM EGCG a me nā helu RTOG ma hope o ka hoʻohana ʻia ʻana o EGCG me nā helu o nā helu kumu (ke mālama ʻia me radiation a chemoradiation).
ʻO nā ʻike nui o ka hoʻopaʻa ʻana i helu ʻia ma lalo (Xiaoling Li et al, Ka Nūpepa o nā Meaʻai Medicinal, 2019):
- ʻO ka hoʻohālikelike o nā helu RTOG i ka pule mua, ʻelua, ʻekolu, ʻehā, ʻelima, a ʻeono ma hope o ka hoʻopili ʻana o EGCG (green tea active) a me ka pule mua a me ka lua ma hope o ka hōʻike ʻana o ka radiotherapy i ka hoʻoliʻiliʻi nui o ka hoʻolele ʻana i nā pilikia / radiation radiation induced esophagitis ( ARIE).
- 44 o 51 mau maʻi i hōʻike i ka pane olakino, me ka pane pane ma 86.3%, me 10 Piha pane a me 34 hapa ʻaoʻao.
- Ma hope o 1, 2, a me 3 mau makahiki, ua loaʻa ka huina ola i 74.5%, 58%, a me 40.5% pākahi.
Panina: ʻO ke kī ʻōmaʻomaʻo (EGCG) e hōʻemi ana i nā pilikia paʻakikī i ka maʻi ʻaʻai Esophageal
Ma muli o kēia mau ʻike koʻikoʻi, ua hoʻoholo ka poʻe noiʻi e hōʻemi ana ka supplementation EGCG i ka ʻai ʻana i nā pilikia / esophagitis me ka ʻole o ka hopena maikaʻi ʻole i ka maikaʻi o ka mālama radiation. Ka inu ʻana ʻO ka'ōmaʻa Green ma ke ʻano he ʻāpana o ka ʻai i kēlā me kēia lā he mea kōkua ia i ka hōʻemi ʻana i ka pilikia o ka ʻai ʻana, ma laila e hoʻomaikaʻi ai i ka maikaʻi o ke ola o nā poʻe maʻi maʻi maʻi esophageal. ʻO ia mau noiʻi lapaʻau, ʻoiai i hana ʻia i loko o kahi pūʻulu liʻiliʻi o nā mea maʻi, ke hoʻohiki nei a kōkua i ka ʻike ʻana i nā hoʻolālā hou e mālama ai i ka chemotherapy a i ʻole ka radiation therapy i hoʻokomo ʻia i nā hopena ʻaoʻao. Eia nō naʻe, pono e loiloi hou ʻia nā hopena o ka EGCG i ka hoʻohaʻahaʻa ʻana i ka lāʻau lapaʻau i hoʻokomo ʻia i ka esophagitis a hōʻoia ʻia i loko o kahi noiʻi lapaʻau nui randomized me kahi pūʻulu hoʻomalu (ua nalowale ka pūʻulu mana i ka haʻawina o kēia manawa) ma mua o ka hoʻokō ʻana ma ke ʻano he protocol lapaʻau.
He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.
ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.
E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.
Mea 'ai pilikino no ka ma'i 'a'ai!
Hoʻololi ka maʻi kanesa me ka manawa. Hoʻopilikino a hoʻololi i kāu meaʻai e pili ana i ka hōʻailona maʻi maʻi, ka mālama ʻana, ke ʻano o ka nohona, nā makemake meaʻai, nā allergies a me nā mea ʻē aʻe.
ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy e pili ana i ko lākou ola a nānā aku no nā hoʻoponopono ʻē aʻe no ka maʻi ʻaʻai ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.