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What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Foods for Mucosal Melanoma Of The Urethra!

Jul 24, 2023

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Introduction

Foods for Mucosal Melanoma Of The Urethra should be personalized for each individual and also must adapt when cancer treatment or tumor genetic change. The personalization and adaptation must consider all the active ingredients or bioactives contained in different foods with respect to cancer tissue biology, genetics, treatments, lifestyle conditions and diet preferences. Hence while nutrition is one of the very important decisions for a cancer patient and individual at risk of cancer to make – how to choose foods to eat is not an easy task.

Mucosal melanoma of the urethra is an extremely rare and aggressive form of cancer that arises in the mucous membrane lining of the urethra. Staging is crucial for determining the extent of mucosal melanoma and guiding treatment decisions. Symptoms of mucosal melanoma can vary, but they may include changes in urinary patterns, bleeding, discomfort, and the presence of a mass. The survival rate for mucosal melanoma is generally low due to its aggressive nature and limited treatment options. Treatment approaches for mucosal melanoma often involve a combination of surgery, radiation therapy, and immunotherapy. Accurate coding using the ICD-10 system ensures proper documentation of mucosal melanoma for medical records. The cause of mucosal melanoma is not well understood, although certain risk factors such as genetics and exposure to UV radiation may contribute. Immunotherapy has emerged as a promising treatment option for mucosal melanoma, and clinical trials continue to explore innovative therapies. The prognosis and life expectancy for patients with mucosal melanoma are generally poor due to late-stage diagnosis and limited treatment efficacy. Early diagnosis through thorough clinical examination and proper diagnostic tests is crucial for improving outcomes. Guidelines provide valuable recommendations for the management of mucosal melanoma. Participating in clinical trials can potentially provide access to experimental treatments. It is important to raise awareness about the signs, symptoms, and management options for mucosal melanoma to improve early detection and treatment outcomes.



For Mucosal Melanoma Of The Urethra does it matter what vegetables, fruits, nuts, seeds one eats?

A very common nutrition question asked by cancer patients and individuals at-genetic risk of cancer is – for cancers like Mucosal Melanoma Of The Urethra does it matter what foods I eat and which I do not? Or if I follow a plant-based diet is that enough for cancer like Mucosal Melanoma Of The Urethra?

For example does it matter if vegetable Calabash is consumed more compared to Black Cabbage? Does it make any difference if fruit Common Grape is preferred over Java Plum? Also if similar choices are made for nuts/seeds like Common Hazelnut over European Chestnut and for pulses like Moth Bean over Mung Bean. And if what I eat matters – then how does one identify foods which are recommended for Mucosal Melanoma Of The Urethra and is it the same answer for everyone with the same diagnosis or genetic risk?

Yes! Foods you eat matters for Mucosal Melanoma Of The Urethra!

Food recommendations may not be the same for everyone and can be different even for the same diagnosis and genetic risk.

All cancers like Mucosal Melanoma Of The Urethra can be characterized by a unique set of biochemical pathways - the signature pathways of Mucosal Melanoma Of The Urethra. Biochemical pathways like Angiogenesis, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, Apoptosis are part of the signature definition of Mucosal Melanoma Of The Urethra.

All foods (vegetables, fruits, nuts, seeds, pulses, oils etc.) and nutritional supplements are made up of more than one active molecular ingredient or bio-actives in different proportions and quantities. Each active ingredient has a unique mechanism of action – which can be activation or inhibition of different biochemical pathways. Simply stated foods and supplements which are recommended are those which do not cause an increase of molecular drivers of cancer but reduce them. Else those foods should not be recommended. Foods contain multiple active ingredients – hence when evaluating foods and supplements you need to consider the impact of all active ingredients cumulatively rather than individually.

For example Common Grape contains active ingredients Curcumin, Linalool, Daidzein, Formononetin, Ellagic Acid. And Java Plum contains active ingredients Curcumin, Apigenin, Daidzein, Formononetin, Ellagic Acid and possibly others.

A common mistake made when deciding and choosing foods to eat for Mucosal Melanoma Of The Urethra – is to evaluate only selected active ingredients contained in foods and ignore the rest. Because different active ingredients contained in foods may have opposing effects on cancer drivers – you cannot cherry pick active ingredients in foods and supplements for making a nutrition decision for Mucosal Melanoma Of The Urethra.

YES – FOOD CHOICES MATTER FOR CANCER. NUTRITION DECISIONS MUST CONSIDER ALL ACTIVE INGREDIENTS OF FOODS.

Skills Needed for Nutrition Personalization for Mucosal Melanoma Of The Urethra?

Personalized nutrition for cancers like Mucosal Melanoma Of The Urethra consists of recommended foods / supplements; not recommended foods / supplements with example recipes which prioritize use of recommended foods. An example of personalized nutrition can be seen at this link.

Deciding which foods are recommended or not is extremely complicated, requiring expertise in Mucosal Melanoma Of The Urethra biology, food science, genetics, biochemistry along with good understanding of how cancer treatments work and associated vulnerabilities by which the treatments could stop being effective.

MINIMUM KNOWLEDGE EXPERTISE NEEDED FOR NUTRITION PERSONALIZATION FOR CANCER ARE: CANCER BIOLOGY, FOOD SCIENCE, CANCER TREATMENTS AND GENETICS.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Characteristics of cancers like Mucosal Melanoma Of The Urethra

All cancers like Mucosal Melanoma Of The Urethra can be characterized by a unique set of biochemical pathways – the signature pathways of Mucosal Melanoma Of The Urethra. Biochemical pathways like Angiogenesis, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, Apoptosis are part of the signature definition of Mucosal Melanoma Of The Urethra. Each individual’s cancer genetics can be different and hence their specific cancer signature could be unique.

The treatments which are effective for Mucosal Melanoma Of The Urethra need to be cognizant of the associated signature biochemical pathways for each cancer patient and individual at genetic risk. Therefore different treatments with different mechanisms of actions are effective for different patients. Similarly and for the same reasons foods and supplements need to be personalized for each individual. Hence some foods and supplements are recommended for Mucosal Melanoma Of The Urethra when taking cancer treatment Doxorubicin, and some foods and supplements are not recommended.

Sources like cBioPortal and many others provide population representative patient anonymized data from clinical trials for all cancer indications. This data consists of clinical trial study details like sample size / number of patients, age groups, gender, ethnicity, treatments, tumor site and any genetic mutations.

TP53, ERBB2, EPHA3, ATRX and MTOR are the top ranked reported genes for Mucosal Melanoma Of The Urethra. TP53 is reported in 33.3 % of the representative patients across all clinical trials. And ERBB2 is reported in 16.7 %. The combined population patient data cover ages from to . 12.5 % of the patient data are identified as men. The Mucosal Melanoma Of The Urethra biology along with reported genetics together define the population represented signature biochemical pathways for this cancer. If the individual cancer tumor genetics or genes contributing to the risk are also known then that should also be used for nutrition personalization.

NUTRITION CHOICES SHOULD MATCH WITH EACH INDIVIDUAL’S CANCER SIGNATURE.

Foods for Mucosal Melanoma Of The Urethra!

Food and Supplements for Mucosal Melanoma Of The Urethra

For Cancer Patients

Cancer patients on treatment or on palliative care need to make decisions on food and supplements – for the needed dietary calories, for managing any treatment side effects and also for improved cancer management. All plant-based foods are not equal and choosing and prioritizing foods which are personalized and customized to ongoing cancer treatment is important and complicated. Here are some examples providing guidelines for making nutrition decisions.

Choose Vegetable CALABASH or BLACK CABBAGE?

Vegetable Calabash contains many active ingredients or bioactives such as Curcumin, Apigenin, Daidzein, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like MAPK Signaling, MYC Signaling, Angiogenesis and PI3K-AKT-MTOR Signaling and others. Calabash is recommended for Mucosal Melanoma Of The Urethra when ongoing cancer treatment is Doxorubicin. This is because Calabash modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Doxorubicin.

Some of the active ingredients or bioactives in vegetable Black Cabbage are Curcumin, Apigenin, Daidzein, Formononetin, Lupeol. These active ingredients manipulate various biochemical pathways like MAPK Signaling and PI3K-AKT-MTOR Signaling and others. Black Cabbage is not recommended for Mucosal Melanoma Of The Urethra when ongoing cancer treatment is Doxorubicin because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

VEGETABLE CALABASH IS RECOMMENDED OVER BLACK CABBAGE FOR Mucosal Melanoma Of The Urethra AND TREATMENT Doxorubicin.

Choose Fruit JAVA PLUM or COMMON GRAPE?

Fruit Java Plum contains many active ingredients or bioactives such as Curcumin, Apigenin, Daidzein, Formononetin, Ellagic Acid. These active ingredients manipulate various biochemical pathways like MAPK Signaling, MYC Signaling, Angiogenesis and PI3K-AKT-MTOR Signaling and others. Java Plum is recommended for Mucosal Melanoma Of The Urethra when ongoing cancer treatment is Doxorubicin. This is because Java Plum modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Doxorubicin.

Some of the active ingredients or bioactives in fruit Common Grape are Curcumin, Linalool, Daidzein, Formononetin, Ellagic Acid. These active ingredients manipulate various biochemical pathways like MAPK Signaling and Angiogenesis and others. Common Grape is not recommended for Mucosal Melanoma Of The Urethra when ongoing cancer treatment is Doxorubicin because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

FRUIT JAVA PLUM IS RECOMMENDED OVER COMMON GRAPE FOR Mucosal Melanoma Of The Urethra AND TREATMENT Doxorubicin.

Choose Nut COMMON HAZELNUT or EUROPEAN CHESTNUT?

Common Hazelnut contains many active ingredients or bioactives such as Curcumin, Daidzein, Formononetin, Lupeol, Lycopene. These active ingredients manipulate various biochemical pathways like MAPK Signaling, MYC Signaling, Angiogenesis and PI3K-AKT-MTOR Signaling and others. Common Hazelnut is recommended for Mucosal Melanoma Of The Urethra when ongoing cancer treatment is Doxorubicin. This is because Common Hazelnut modifies those biochemical pathways which have been scientifically reported to sensitize the effect of Doxorubicin.

Some of the active ingredients or bioactives in European Chestnut are Curcumin, Apigenin, Daidzein, Formononetin, Ellagic Acid. These active ingredients manipulate various biochemical pathways like PI3K-AKT-MTOR Signaling and others. European Chestnut is not recommended for Mucosal Melanoma Of The Urethra when ongoing cancer treatment is Doxorubicin because it modifies those biochemical pathways which make the cancer treatment resistant or less responsive.

COMMON HAZELNUT IS RECOMMENDED OVER EUROPEAN CHESTNUT FOR Mucosal Melanoma Of The Urethra AND TREATMENT Doxorubicin.

For Individuals with Genetic Risk of Cancer

The question asked by individuals who have genetic risk of Mucosal Melanoma Of The Urethra or familial history is “What Should I Eat Differently from Before?” and how they should choose foods and supplements to manage risks of the disease. Since for cancer risk there is nothing actionable in terms of treatment – decisions of foods and supplements become important and one of the very few actionable things which can be done. All plant-based foods are not equal and based on identified genetics and pathway signature – the choices of food and supplements should be personalized.

Choose Vegetable BITTER GOURD or LEEK?

Vegetable Bitter Gourd contains many active ingredients or bioactives such as Curcumin, Apigenin, Catechol, Delphinidin, Formononetin. These active ingredients manipulate various biochemical pathways like MAPK Signaling, Hypoxia, EPHRIN Signaling and PI3K-AKT-MTOR Signaling and others. Bitter Gourd is recommended for risk of Mucosal Melanoma Of The Urethra when associated genetic risk is ATRX. This is because Bitter Gourd increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in vegetable Leek are Curcumin, Apigenin, Catechol, Delphinidin, Formononetin. These active ingredients manipulate various biochemical pathways like PI3K-AKT-MTOR Signaling and others. Leek is not recommended when risk of Mucosal Melanoma Of The Urethra when associated genetic risk is ATRX because it increases the signature pathways of it.

VEGETABLE BITTER GOURD IS RECOMMENDED OVER LEEK FOR ATRX GENETIC RISK OF CANCER.

Choose Fruit NANCE or PUMMELO?

Fruit Nance contains many active ingredients or bioactives such as Curcumin, Apigenin, Catechol, Delphinidin, Formononetin. These active ingredients manipulate various biochemical pathways like MAPK Signaling, Hypoxia and PI3K-AKT-MTOR Signaling and others. Nance is recommended for risk of Mucosal Melanoma Of The Urethra when associated genetic risk is ATRX. This is because Nance increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in fruit Pummelo are Curcumin, Quercetin, Apigenin, Catechol, Delphinidin. These active ingredients manipulate various biochemical pathways like Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling and others. Pummelo is not recommended when risk of Mucosal Melanoma Of The Urethra when associated genetic risk is ATRX because it increases the signature pathways of it.

FRUIT NANCE IS RECOMMENDED OVER PUMMELO FOR ATRX GENETIC RISK OF CANCER.

Choose Nut BUTTERNUT or PUMPKIN SEEDS?

Butternut contains many active ingredients or bioactives such as Curcumin, Apigenin, Catechol, Delphinidin, Formononetin. These active ingredients manipulate various biochemical pathways like MAPK Signaling, Hypoxia, PI3K-AKT-MTOR Signaling and EPHRIN Signaling and others. Butternut is recommended for risk of Mucosal Melanoma Of The Urethra when associated genetic risk is ATRX. This is because Butternut increases those biochemical pathways which counteract the signature drivers of it.

Some of the active ingredients or bioactives in Pumpkin Seeds are Beta-sitosterol, Oleic Acid, Gamma-linolenic Acid, Linolenic Acid, Stigmasterol. These active ingredients manipulate various biochemical pathways like MAPK Signaling, EPHRIN Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling and others. Pumpkin Seeds is not recommended when risk of Mucosal Melanoma Of The Urethra when associated genetic risk is ATRX because it increases the signature pathways of it.

BUTTERNUT IS RECOMMENDED OVER PUMPKIN SEEDS FOR ATRX GENETIC RISK OF CANCER.


In Conclusion

Foods and Supplements chosen are important decisions for cancers like Mucosal Melanoma Of The Urethra. Mucosal Melanoma Of The Urethra patients and individuals with genetic-risk always have this question: “What foods and nutritional supplements are recommended for me and which are not?” There is a common belief which is a misconception that all plant-based foods could be beneficial or not but would not be harmful. Certain foods and supplements can interfere with cancer treatments or promote molecular pathway drivers of cancer.

There are different types of cancer indications like Mucosal Melanoma Of The Urethra, each with different tumor genetics with further genomic variations across each individual. Further every cancer treatment and chemotherapy has a unique mechanism of action. Each food like Calabash contains various bioactives in different quantities, which have an impact on different and distinct sets of biochemical pathways. The definition of personalized nutrition is individualized food recommendations for the cancer indication, treatments, genetics, lifestyle and other factors. Nutrition personalization decisions for cancer require knowledge of cancer biology, food science and an understanding of different chemotherapy treatments. Finally when there are treatment changes or new genomics is identified – the nutrition personalization needs re-evaluation.

The addon nutrition personalization solution makes the decision making easy and removes all the guesswork in answering the question, “What foods should I choose or not choose for Mucosal Melanoma Of The Urethra?”. The addon multi-disciplinary team includes cancer physicians, clinical scientists, software engineers and data scientists.


Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.

References

Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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