Highlights
No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Mucosal Melanoma Of The Urethra when undergoing chemotherapy or when you determine you have a genetic risk for developing Mucosal Melanoma Of The Urethra because of ERBB2 and EPHA3 gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.
There is no one answer to this question for cancers such as Mucosal Melanoma Of The Urethra which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.
In short – the process to answer questions like “Should I Avoid eating fruit Quince” or “Include fruit Partridgeberry in my diet” or “Should I reduce consumption of vegetable Swede” or “Can I take Rutaecarpine and Maqui supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.
RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO MUCOSAL MELANOMA OF THE URETHRA, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.
The overall objective of personalized nutrition for Mucosal Melanoma Of The Urethra is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.
RECOMMENDATION: UPDATE YOUR NUTRITION FOR MUCOSAL MELANOMA OF THE URETHRA, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.
About Mucosal Melanoma Of The Urethra
cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.
Following key highlights are derived from clinical data for Mucosal Melanoma Of The Urethra from cBioPortal. 12.5% of males and 87.5% of females were the distribution of gender in these clinical studies. From a patient sample size of 9; the top genes with mutations and other abnormalities for Mucosal Melanoma Of The Urethra include genes TP53, ERBB2, EPHA3, ATRX and MTOR. The occurrence frequency distribution for these genes respectively is 33.3%, 16.7%, 16.7%, 16.7% and 16.7%. These tumor genetic details of Mucosal Melanoma Of The Urethra are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Mucosal Melanoma Of The Urethra.
Significance of Nutrition for Mucosal Melanoma Of The Urethra
All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Mucosal Melanoma Of The Urethra. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.
For example Quince includes active ingredients Oleic Acid, Vitamin C, Chlorogenic Acid, Modified Citrus Pectin, Quercitrin and others. And Partridgeberry contains active ingredients Resveratrol, Beta-sitosterol, Stigmasterol and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.
For cancers like Mucosal Melanoma Of The Urethra, activation or inhibition of selected biochemical pathways like Angiogenesis, MAPK Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Mucosal Melanoma Of The Urethra, while eating some other foods and supplements may not be recommended.
One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR MUCOSAL MELANOMA OF THE URETHRA – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.
Foods for Mucosal Melanoma Of The Urethra undergoing chemotherapy treatment
In Mucosal Melanoma Of The Urethra – the genes TP53, ERBB2, EPHA3, ATRX and MTOR have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Mucosal Melanoma Of The Urethra are Angiogenesis, MAPK Signaling, PI3K-AKT-MTOR Signaling and others. Pazopanib is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers Angiogenesis, MAPK Signaling, PI3K-AKT-MTOR Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.
RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.
Eat more pulses, Winged Bean?
Pulses are an important part of many diets. The active ingredients contained in Winged Bean are Vitamin C, Oleic Acid, Betulinic Acid, Linolenic Acid, Linoleic Acid among others.
Betulinic Acid can manipulate biochemical pathways MAPK Signaling, Angiogenesis and MYC Signaling. Vitamin C has biological action on biochemical pathways RAS-RAF Signaling, PI3K-AKT-MTOR Signaling and MAPK Signaling.
When treating Mucosal Melanoma Of The Urethra with chemotherapy Pazopanib – Foods like Winged Bean are recommended. This is because the active ingredients Betulinic Acid and Vitamin C contained in Winged Bean support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: WINGED BEAN IS RECOMMENDED FOR MUCOSAL MELANOMA OF THE URETHRA ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.
Eat more vegetables, Giant Butterbur or Swede?
Vegetables are an important part of many diets. The active ingredients contained in Giant Butterbur are Vitamin C, Beta-sitosterol, Melatonin, Kaempferol, Vitamin A among others. While the active ingredients contained in Swede are Lycopene, Oleic Acid, Linolenic Acid, Linoleic Acid, Folic Acid and others.
Vitamin C can manipulate biochemical pathways MAPK Signaling, Angiogenesis and RAS-RAF Signaling. Beta-sitosterol has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and Angiogenesis.
Linoleic Acid can manipulate biochemical pathways Angiogenesis. Folic Acid has biological action on biochemical pathways MAPK Signaling, MYC Signaling and RAS-RAF Signaling. And so on.
When treating Mucosal Melanoma Of The Urethra with chemotherapy Pazopanib – Foods like Giant Butterbur are recommended compared to Swede. This is because the active ingredients Linoleic Acid and Folic Acid in Swede interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Vitamin C and Beta-sitosterol contained in Giant Butterbur support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: GIANT BUTTERBUR IS RECOMMENDED OVER SWEDE FOR MUCOSAL MELANOMA OF THE URETHRA ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.
Eat more fruits, Partridgeberry or Quince?
Fruits are an important part of many diets. The active ingredients contained in Partridgeberry are Resveratrol, Beta-sitosterol, Stigmasterol among others. While the active ingredients contained in Quince are Oleic Acid, Vitamin C, Chlorogenic Acid, Modified Citrus Pectin, Quercitrin and others.
Resveratrol can manipulate biochemical pathways Angiogenesis, MYC Signaling and RAS-RAF Signaling. Beta-sitosterol has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, Angiogenesis and MYC Signaling.
Quercitrin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Linoleic Acid has biological action on biochemical pathways Angiogenesis. And so on.
When treating Mucosal Melanoma Of The Urethra with chemotherapy Pazopanib – Foods like Partridgeberry are recommended compared to Quince. This is because the active ingredients Quercitrin and Linoleic Acid in Quince interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Resveratrol and Beta-sitosterol contained in Partridgeberry support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: PARTRIDGEBERRY IS RECOMMENDED OVER QUINCE FOR MUCOSAL MELANOMA OF THE URETHRA ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.
Eat more nuts, Walnut or Brazil Nut?
Nuts are an important part of many diets. The active ingredients contained in Walnut are Ellagic Acid, Quercetin, D-limonene, Juglone, Protocatechuic Acid among others. While the active ingredients contained in Brazil Nut are Oleic Acid, Vitamin E, Linolenic Acid, Folic Acid, Lecithin and others.
Ellagic Acid can manipulate biochemical pathways Angiogenesis, MAPK Signaling and RAS-RAF Signaling. D-limonene has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and Growth Factor Signaling.
Lecithin can manipulate biochemical pathways MAPK Signaling, Angiogenesis and MYC Signaling. Folic Acid has biological action on biochemical pathways RAS-RAF Signaling, PI3K-AKT-MTOR Signaling and MAPK Signaling. And so on.
When treating Mucosal Melanoma Of The Urethra with chemotherapy Pazopanib – Foods like Walnut are recommended compared to Brazil Nut. This is because the active ingredients Lecithin and Folic Acid in Brazil Nut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Ellagic Acid and D-limonene contained in Walnut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: WALNUT IS RECOMMENDED OVER BRAZIL NUT FOR MUCOSAL MELANOMA OF THE URETHRA ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.

Foods for Genetic Risk of Mucosal Melanoma Of The Urethra
One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. ERBB2 and EPHA3 are two genes whose abnormalities are risk factors for Mucosal Melanoma Of The Urethra. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Mucosal Melanoma Of The Urethra can be used as a guide for coming up with a recommended personalized nutrition plan. For Mucosal Melanoma Of The Urethra gene ERBB2 has causative impact on biological pathways like Growth Factor Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling. And EPHA3 has a causative impact on biological pathways like . Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like ERBB2 and EPHA3 should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes ERBB2 and EPHA3 should be avoided.
Eat more pulses, Mung Bean or Black-eyed Pea?
The active ingredients contained in Mung Bean are Oleic Acid, Linolenic Acid, Quercetin, Vitamin C, Stigmasterol among others. While the active ingredients contained in Black-eyed Pea are Daidzein, Oleic Acid, Linolenic Acid, Vitamin C, Stigmasterol and others.
Quercetin can manipulate biochemical pathways Cell Cycle Checkpoints, P53 Signaling and MYC Signaling. Vitamin C has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, Growth Factor Signaling and Apoptosis.
Beta-carotene can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Vitamin A has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.
For genetic risk of Mucosal Melanoma Of The Urethra due to abnormalities in genes ERBB2 and EPHA3 – Foods like Mung Bean are recommended compared to Black-eyed Pea. This is because the active ingredients Beta-carotene and Vitamin A in Black-eyed Pea further promote the effects of genes on the biochemical pathways. While the active ingredients Quercetin and Vitamin C contained in Mung Bean together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: MUNG BEAN IS RECOMMENDED OVER BLACK-EYED PEA FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE URETHRA DUE TO GENES ERBB2 AND EPHA3
Eat more vegetables, Cassava or Lotus?
The active ingredients contained in Cassava are Oleic Acid, Linolenic Acid, Beta-sitosterol, Vitamin C, Linoleic Acid among others. While the active ingredients contained in Lotus are Oleic Acid, Linolenic Acid, Quercetin, Beta-sitosterol, Vitamin C and others.
Vitamin C can manipulate biochemical pathways Cell Cycle Checkpoints, P53 Signaling and MYC Signaling. Beta-sitosterol has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, Apoptosis and Cell Cycle Checkpoints.
Fisetin can manipulate biochemical pathways MYC Signaling. Linoleic Acid has biological action on biochemical pathways Growth Factor Signaling. And so on.
For genetic risk of Mucosal Melanoma Of The Urethra due to abnormalities in genes ERBB2 and EPHA3 – Foods like Cassava are recommended compared to Lotus. This is because the active ingredients Fisetin and Linoleic Acid in Lotus further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Cassava together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: CASSAVA IS RECOMMENDED OVER LOTUS FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE URETHRA DUE TO GENES ERBB2 AND EPHA3
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
Eat more fruits, Currant or Peach?
The active ingredients contained in Currant are Cianidanol, Oleic Acid, Delphinidin, Linolenic Acid, Quercetin among others. While the active ingredients contained in Peach are Oleic Acid, Linolenic Acid, Beta-sitosterol, Vitamin C, Modified Citrus Pectin and others.
Cianidanol can manipulate biochemical pathways Cell Cycle Checkpoints, P53 Signaling and MYC Signaling. Delphinidin has biological action on biochemical pathways Growth Factor Signaling, PI3K-AKT-MTOR Signaling and MYC Signaling.
Fisetin can manipulate biochemical pathways MYC Signaling. Vitamin A has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.
For genetic risk of Mucosal Melanoma Of The Urethra due to abnormalities in genes ERBB2 and EPHA3 – Foods like Currant are recommended compared to Peach. This is because the active ingredients Fisetin and Vitamin A in Peach further promote the effects of genes on the biochemical pathways. While the active ingredients Cianidanol and Delphinidin contained in Currant together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: CURRANT IS RECOMMENDED OVER PEACH FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE URETHRA DUE TO GENES ERBB2 AND EPHA3
Eat more nuts, Pistachio or Macadamia Nut?
The active ingredients contained in Pistachio are Vitamin E, Oleic Acid, Resveratrol, Linolenic Acid, Beta-sitosterol among others. While the active ingredients contained in Macadamia Nut are Beta-sitosterol, Palmitic Acid, Lauric Acid, Folic Acid, Myristic Acid and others.
Beta-sitosterol can manipulate biochemical pathways Cell Cycle Checkpoints, P53 Signaling and MYC Signaling. Vitamin E has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, Growth Factor Signaling and Apoptosis.
Palmitic Acid can manipulate biochemical pathways Growth Factor Signaling. Lauric Acid has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and Growth Factor Signaling. And so on.
For genetic risk of Mucosal Melanoma Of The Urethra due to abnormalities in genes ERBB2 and EPHA3 – Foods like Pistachio are recommended compared to Macadamia Nut. This is because the active ingredients Palmitic Acid and Lauric Acid in Macadamia Nut further promote the effects of genes on the biochemical pathways. While the active ingredients Beta-sitosterol and Vitamin E contained in Pistachio together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: PISTACHIO IS RECOMMENDED OVER MACADAMIA NUT FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE URETHRA DUE TO GENES ERBB2 AND EPHA3

In Summary
An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.
“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.
The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.
You can get started NOW and design a personalized nutrition plan for Mucosal Melanoma Of The Urethra by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

References
- Msk Impact 2017
- Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
- Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors.
- Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7.
- Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition.
- β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation.
- Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution.
- Role of phospholipase D in migration and invasion induced by linoleic acid in breast cancer cells.
- Sequential protooncogene expression in regenerating kidney following acute renal injury.
- Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors.
- D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis.
- New concepts in phospholipase D signaling in inflammation and cancer.
- Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin.
- β-carotene Inhibits Expression of c-Myc and Cyclin E in Helicobacter pylori-infected Gastric Epithelial Cells.
- Vitamin A regulates Akt signaling through the phospholipid fatty acid composition.
- Molecular docking analysis of Cianidanol fromGinkgo biloba with HER2+ breast cancer target.
- Identification of new potent phthalazine derivatives with VEGFR-2 and EGFR kinase inhibitory activity.
- Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression.
- EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice.
- Clinical pharmacodynamics of antihistamines.
- HyperFoods: Machine intelligent mapping of cancer-beating molecules in foods.
- Resveratrol, pterostilbene, and piceatannol in vaccinium berries.
- Fisetin: a dietary antioxidant for health promotion.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.