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Royal Jelly and Chemo Induced Mucositis

Jul 7, 2021

Estimated reading time: 4 minutes
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Cancer patients often seek ways to treat chemo-induced mouth sores naturally. Clinical studies have shown that the use of natural bee products- royal jelly or honey, can reduce the frequency and duration of oral mucositis- formation of open sores in the mouth- a common chemo and radiotherapy related adverse side-effect in cancer patients. For cancer related side-effects such as chemo-induced mucositis, right nutrition matters.

Royal Jelly and Honey

Royal jelly, or bee’s milk, is a special secretion made by nurse bees of the colony specifically for the larvae of the queen bee, who is exclusively fed and surrounded by this jelly, instead of the regular honey and pollen fed to the other bees. Although it is disputed if it is the sole access to the jelly or not having access to the normal honey and pollen that leads to the superior characteristics of a queen bee, it is believed that because of its antioxidant and anti-microbial properties, royal jelly has been able to significantly increase the lifespan of queen bees. Thus, it is without surprise that royal jelly is commonly used around the globe in cosmetics (valiant effort to reverse aging), and as dietary supplements. While it is still being proven through more recent studies, these special properties of natural bee products are showing signs of greatly aiding patients from the toxic effects of chemotherapy.

Royal-Jelly for Chemotherapy Side-Effect Mucositis  : natural remedy for cancer

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Can we use Royal Jelly to help treat Chemo-induced Oral Mucositis/ Mouth Sores Naturally?

One of the most common side effects of both chemotherapy and radiation is oral mucositis. Oral mucositis, which essentially results in open sores in the mouth, can severely decrease a patient’s quality of life because of the pain, inability to eat, and an increased risk of subsequent infection. In addition, this can increase the length of one’s chemo treatment because if someone is experiencing severe mucositis, then their chemo dosages will be reduced. In a study done by medical researchers from the Nagasaki Graduate School of Biomedical Sciences, the researchers did a holistic study on royal jelly and its effects in relation to cancer as well as its specific toxicities to the body. After analyzing a range of studies on the matter, the researchers found that royal jelly supplementation can lead to anti-tumor growth as well as in aiding against anti-cancer induced toxicities. For example, in a randomized single blind study done on head and neck cancer patients testing out royal jelly’s effect in reducing oral mucositis, the “results showed that all patients in the control group experienced grade 3 mucositis, which progressed to grade 4 in one patient at 1 month after treatment but that grade 3 mucositis was observed in only 71.4% of patients in the royal jelly treated group” (Miyata Y et al, Int J Mol Sci. 2018).

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Can we use Honey to help treat Chemo-induced Oral Mucositis/ Mouth Sores Naturally?

In addition to royal-jelly, other natural bee products such as regular honey are also proving to be effective in hampering painful toxicities/chemo side-effect such as oral mucositis/mouth sores in cancer patients. And the beauty of such products is that they are widely accessible to all financial groups unlike some of the current treatment options which include cryotherapy, or cold therapy, and low-level light therapy. In a study done by researchers from the United Kingdom, testing if honey is an appropriate treatment option for chemo induced mucositis, the researchers found four scientifically published papers which show that “honey reduces the frequency, duration, and stage of mucositis in children receiving chemotherapy” (Friend A et al, J Trop Pediatr. 2018). 

Are there any Side Effects for Royal Jelly Capsules?

When taken in right doses, Royal jelly in the form of food or capsules is safe in most people. However, being a bee product, in certain people with asthma or allergies, royal jelly in either food or capsule form can lead to very serious allergic reactions.

In Conclusion

In essence, while a lot more research and medical trials are needed, natural remedy such as the use of royal jelly and honey seem to be especially beneficial when it comes to reducing the effects of chemotherapy induced oral mucositis or mouth sores. And being that these are widely consumed natural products as part of diet/nutrition, no harsh toxicities have been recorded in cancer, stemming from products like honey itself.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.


Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.

Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer.Taking the right nutrition and supplements based on scientific considerations  (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.

Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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