Ukudla Okusabalalisa I-Midline Glioma!

Isingeniso

Ukudla Okusabalalisa I-Midline Glioma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Mayelana ne-Diffuse Midline Glioma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza onjenge-Diffuse Midline Glioma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjenge-Diffuse Midline Glioma?

Isibonelo, ingabe kunendaba ukuthi iButterbur yemifino idliwa kakhulu uma iqhathaniswa ne-Oyster Mushroom? Ingabe kuyawenza umehluko uma isithelo iSapodilla sithandwa kuneNance? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Butternut phezu kwe-Chestnut kanye nama-pulses afana no-Broad Bean phezu kwe-Catjang Pea. Futhi uma lokho engikudlayo kunendaba - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Diffuse Midline Glioma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ubungozi bofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Diffuse Midline Glioma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo iSapodilla iqukethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Delphinidin. Futhi i-Nance iqukethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Delphinidin futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-Diffuse Midline Glioma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Diffuse Midline Glioma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Ukuze Uhlukanise I-Midline Glioma?

Ukondleka komuntu siqu komdlavuza njenge-Diffuse Midline Glioma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Diffuse Midline Glioma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Diffuse Midline Glioma

Yonke imidlavuza efana ne-Diffuse Midline Glioma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Diffuse Midline Glioma. Izindlela zamakhemikhali ezinto eziphilayo njenge-DNA Repair, Angiogenesis, Hypoxia, PI3K-AKT-MTOR Signaling ziyingxenye yencazelo yesiginesha ye-Diffuse Midline Glioma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Diffuse Midline Glioma zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kuyanconywa ku-Diffuse Midline Glioma lapho uthatha ukwelashwa komdlavuza i-Temozolomide, futhi okunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-IDH1, TP53, H3F3B, TERT kanye ne-ATRX yizakhi zofuzo ezisezingeni eliphezulu ezibikiwe ze-Diffuse Midline Glioma. I-IDH1 ibikwa ku-35.7 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-TP53 ibikwa ku-35.1%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. I-% yedatha yesiguli ikhonjwa njengabesilisa. I-Diffuse Midline Glioma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithasiselo Zokusabalalisa I-Glioma Midline

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha iVegetable GIANT BUTTERBUR noma OYSTER MUSHROOM?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Delphinidin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, NFKB Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Giant Butterbur iyanconywa nge-Diffuse Midline Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi i-Butterbur Enkulu iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Oyster Mushroom yemifino yi-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Delphinidin. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana Ne-Extracellular Matrix Remodelling, i-NFKB Signaling, Cell Cycle kanye ne-P53 Signaling nezinye. I-Oyster Mushroom ayinconyelwe i-Diffuse Midline Glioma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

IBUTTERBUR ENKULU YEZINJINI INCONYWA NGAPHEZU KWE-OYSTER MUSHROOM UKUZE I-Diffuse Midline Glioma KANYE NOKWELASHWA I-Temozolomide.

Khetha Isithelo NANCE noma SAPODILLA?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Delphinidin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR Signaling ne-Hypoxia nezinye. I-Nance inconywa nge-Diffuse Midline Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi uNance ulungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni iSapodilla yiCurcumin, Apigenin, Formononetin, Lupeol, Delphinidin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, i-Extracellular Matrix Remodelling, i-TGFB Signaling kanye nokulungiswa kwe-DNA nokunye. I-Sapodilla ayinconyelwe i-Diffuse Midline Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO NANCE KUNCONYWA NGENXA YE-SAPODILLA YE-Diffuse Midline Glioma KANYE NOKWELASHWA I-Temozolomide.

Khetha Nut BUTTERNUT noma CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Delphinidin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling, JAK-STAT Signaling, PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Butternut iyanconywa nge-Diffuse Midline Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Ellagic Acid, i-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling, Oxidative Stress kanye ne-TWEAK Signaling nezinye. I-Chestnut ayinconyelwe i-Diffuse Midline Glioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-CHESTNUT UKUZE I-Diffuse Midline Glioma KANYE NOKWELASHWA I-Temozolomide.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abasengozini yofuzo ye-Diffuse Midline Glioma noma umlando womndeni uthi "Yini Okufanele Ngidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GARDEN CRESS noma i-BROCCOLI?

I-Vegetable Garden Cress iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, Cell Cycle, PI3K-AKT-MTOR Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Garden Cress inconyelwa engcupheni ye-Diffuse Midline Glioma lapho ubungozi bofuzo obuhlobene kuyi-ATRX. Lokhu kungenxa yokuthi i-Garden Cress inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli besiginesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Broccoli yemifino yi-Curcumin, i-Quercetin, i-Resveratrol, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling, i-Cell Cycle Checkpoints kanye ne-P53 Signaling nezinye. I-Broccoli ayinconywa uma ingozi ye-Diffuse Midline Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-VEGETABLE GARDEN CRESS INCONYISWA NGAPHEZU KWE-BROCCOLI YE-ATRX GENETIC RISK OF CANCER.

Khetha isithelo se-PAPAYA noma i-PUMMELO?

I-Fruit Papaya iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, Cell Cycle, JAK-STAT Signaling kanye ne-MYC Signaling nezinye. I-Papaya inconywa ngengozi ye-Diffuse Midline Glioma lapho ubungozi bofuzo obuhambisanayo kuyi-ATRX. Lokhu kungenxa yokuthi i-Papaya inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling kanye ne-Cell Cycle Checkpoints nezinye. I-Pummelo ayinconywa uma ingozi ye-Diffuse Midline Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-PAPAYA YESITHELO INCONYISWA NGAPHEZU KWE-PUMMELO YE-ATRX GENETIC RISK OF CANCER.

Khetha Nut COMMON WALNUT noma EUROPEAN CHESTNUT?

I-Walnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin, i-Ellagic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, Cell Cycle, JAK-STAT Signaling kanye ne-P53 Signaling nezinye. I-Walnut evamile inconywa engozini ye-Diffuse Midline Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX. Lokhu kungenxa yokuthi i-Common Walnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling nezinye. I-Chestnut yaseYurophu ayinconywa uma ingozi ye-Diffuse Midline Glioma uma ingozi yofuzo ehlotshaniswa nayo i-ATRX ngoba inyusa izindlela zayo zokusayina.

I-WALNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT YAseYurophu NGENGOZI YOFUZO YE-ATRX YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njenge-Diffuse Midline Glioma. Iziguli ezisabalalisa i-Midline Glioma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithasiselo zokudla okunempilo enginconyelwe zona futhi okungakunconyelwe?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Diffuse Midline Glioma, ngayinye enezakhi zofuzo zesimila esinokwehlukahlukana kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Giant Butterbur kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Diffuse Midline Glioma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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